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List of works by Margaret A Goodell

A gallon of sweat to make a pint of blood

scientific article published on June 2014

A new allele of Lyl1 confirms its important role in hematopoietic stem cell function

scientific article

Acute loss of TET function results in aggressive myeloid cancer in mice

scientific article

Adenoviral transduction of mouse hematopoietic stem cells

scientific article published in March 2003

Ageing and rejuvenation of tissue stem cells and their niches

scientific article published in 2022

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

scientific article

Altered phenotype and reduced function of muscle-derived hematopoietic stem cells

scientific article published in September 2003

An Argument against a Role for Oct4 in Somatic Stem Cells

scientific article published on 01 October 2007

An in vivo propagated human acute myeloid leukemia expressing ABCA3.

scientific article published in March 2004

Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation

scientific article published on 14 November 2002

Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery

scientific journal article

Bridge over troubled stem cells

scientific article

Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting

scientific article published on May 2007

CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells

scientific article

CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation

scientific article

CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway

scientific article

Chk1 haploinsufficiency results in anemia and defective erythropoiesis

scientific article

Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis

scientific article

Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells

scientific article

Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man.

scientific article published in May 2003

Confounding by repetitive elements and CpG islands does not explain the association between hypomethylation and genomic instability

scientific article

Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis

scientific article published on 30 May 2022

Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

scientific article published in 2024

DNA methylation and de-methylation using hybrid site-targeting proteins

scientific article published on 06 November 2018

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias

scientific article published on 08 August 2016

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

scientific article published on June 2016

DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells.

scientific article published on 12 July 2018

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

scientific article published on 18 July 2016

DNMT3A in haematological malignancies

scientific article

DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia

scientific article published on 22 June 2016

Detection of hematopoietic stem cells by flow cytometry.

scientific article published on January 2011

Differential mRNA processing in hematopoietic stem cells

scientific article published on 22 December 2005

Direct conversion of skin cells into blood: alchemy or science?

scientific article published on February 2011

Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

scientific article

Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells

scientific article published on 14 August 2014

Dnmt3a is essential for hematopoietic stem cell differentiation

scientific article

Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation.

scientific article

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

scientific article published on December 1997

Dynamic DNA methylation discovered during HSC differentiation

scientific article published on January 2015

EDITORIAL RETRACTION

article

Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics

scientific article

Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2

scientific article

Epigenetics in hematology: introducing a collection of reviews

scientific article published on 01 April 2013

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

scientific article

Erratum: Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

scientific article published in Nature

Evidence for diversity in transcriptional profiles of single hematopoietic stem cells

scientific article

Failure of bone marrow cells to transdifferentiate into neural cells in vivo

scientific article published in August 2002

Flow cytometry analysis of murine hematopoietic stem cells

scientific article

Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome

scientific article

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

scientific article published on 15 January 2019

Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors

scientific journal article

Hematopoietic fingerprints: an expression database of stem cells and their progeny

scientific article

Hematopoietic stem cell characterization and isolation

scientific article

Hematopoietic stem cell development: an epigenetic journey

scientific article published on January 2014

Hematopoietic stem cells do not engraft with absolute efficiencies

scientific article published on 4 October 2005

Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.

scientific article published on October 2016

Identification and characterization of side population cells in embryonic stem cell cultures

scientific article

Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells

scientific article

Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response ⬇️

scientific article published on September 9, 2011

Inflammatory signals regulate hematopoietic stem cells

scientific article published on 11 January 2011

Introduction to a review series on hematopoietic stem cells.

scientific article published on 11 March 2015

Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro

scientific article

Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling

scientific article

LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner

scientific article

Large conserved domains of low DNA methylation maintained by Dnmt3a

scientific article published on 24 November 2013

Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice

scientific article published on September 2012

Long non-coding RNAs control hematopoietic stem cell function

scientific article published on 12 March 2015

Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome

scientific article published on 11 March 2020

MOABS: model based analysis of bisulfite sequencing data

scientific article

Mechanisms of hematopoietic stem cell aging

scientific article

Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes

scientific article published on 18 May 2016

Molecular signatures of proliferation and quiescence in hematopoietic stem cells

scientific article

Mouse hematopoietic stem cell identification and analysis

scientific article published on January 2009

Multipotential stem cells and 'side population' cells.

scientific article

Muscle-derived hematopoietic stem cells are hematopoietic in origin

scientific article

New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells

scientific article

New insights into the biology of acute myeloid leukemia with mutated NPM1

scientific article published on 10 January 2019

Noncoding Regulatory RNAs in Hematopoiesis.

scientific article published on 23 February 2016

Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.

scientific article published on 31 August 2016

Parental permissions: H19 and keeping the stem cell progeny under control

scientific article published in August 2013

Perspectives and future directions for epigenetics in hematology

scientific article published on 21 May 2013

Phenotype and hematopoietic potential of side population cells throughout embryonic development

scientific article published on 12 June 2003

Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator

scientific article published on 12 July 2007

Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans

scientific article

Primitive adult hematopoietic stem cells can function as osteoblast precursors

scientific article

Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells

scientific article

Purification of hematopoietic stem cells using the side population

scientific article

Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection

scientific article

Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

scientific article published on 30 January 2012

Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways

scientific article published on 21 November 2006

Rising from the crypt: decreasing DNA methylation during differentiation of the small intestine

scientific article published on 28 May 2013

Roles of Sca-1 in hematopoietic stem/progenitor cell function

scientific article

Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

scientific article

Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population

scientific article published in May 2002

Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression

scientific article published on 18 November 2009

Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates

scientific article published on 16 November 2003

Single-cell technology meets hematology: introduction to a review series

article

Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments

scientific article published on May 2015

Somatic stem cell plasticity: current evidence and emerging concepts.

scientific article

Stem Cells and Aging: What's Next?

scientific article

Stem cell plasticity: from transdifferentiation to macrophage fusion.

scientific article published on February 2004

Stem cells and healthy aging

scientific article

Stem cells: is there a future in plastics? ⬇️

scientific article published on December 1, 2001

Stem-cell “plasticity”: befuddled by the muddle ⬇️

scientific article published on May 1, 2003

TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs

scientific article

Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system

scientific article published on April 2004

Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells

scientific article published on 31 May 2013

The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool

scientific article published on 09 May 2012

The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation

scientific article published on 11 August 2010

The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging

scientific article published on 10 October 2006

The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells

scientific article

The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation

scientific article published on January 2008

The pogo transposable element family of Drosophila melanogaster

scientific article published on March 1992

The stem cell parade

The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors

scientific article

Transient RNA interference in hematopoietic progenitors with functional consequences

scientific article published in August 2003

Use of CD9 expression to enrich for porcine hematopoietic progenitors

scientific article

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome

scientific article

mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert)

scientific article

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