List of works - Stephan Ludwig

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

scientific article (publication date: September 2007)

Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

scientific article

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

scientific article published on 17 January 2007

Caspase 3 activation is essential for efficient influenza virus propagation

scientific article

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression

scientific article

NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation

scientific article published on 12 May 2004

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

scientific article

Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

scientific article

The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells

scientific article published on 9 September 2010

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence

scientific article published on August 2006

The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway

scientific article

MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1

scientific article

Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

scientific article published in Journal of Biological Chemistry

3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways

scientific article

The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

scientific article published on November 2002

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

scientific article published on 7 January 2008

A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway

scientific article published on 12 March 2009

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

scientific article

Interplay between influenza A virus and the innate immune signaling

scientific article published on 25 September 2009

Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity

scientific article (publication date: July 2007)

Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells

scientific article published on 8 January 2004

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

scientific article published on June 2004

Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase

scientific article published in March 2000

Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling

scientific article

Influenza-virus-induced signaling cascades: targets for antiviral therapy?

scientific article

Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury

scientific article published on 17 February 2012

Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses

scientific article published on August 1, 1991

Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1.

scientific article

Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells

scientific article

The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity

scientific article published in Journal of Biological Chemistry

MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells

scientific article published on May 2001

Multiple signaling pathways regulate NF-kappaB-dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells

article

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

article by Stephan Ludwig published 6 May 2009 in Journal of Antimicrobial Chemotherapy

Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death

scientific article (publication date: 26 October 2001)

Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes

scientific article published in Journal of Biological Chemistry

Ras-independent Activation of the Raf/MEK/ERK Pathway upon Calcium-induced Differentiation of Keratinocytes

scientific article published in Journal of Biological Chemistry

Antigenic and genetic analyses of H1N1 influenza A viruses from European pigs

scientific article published in March 1997

European swine virus as a possible source for the next influenza pandemic?

scientific article published in October 1995

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

scientific article published on 06 May 2009

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

scientific article published on 28 September 2009

Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway

scientific article

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo

scientific article

MEK inhibition impairs influenza B virus propagation without emergence of resistant variants

scientific article published on March 2004

Analysis of influenza A virus nucleoproteins for the assessment of molecular genetic mechanisms leading to new phylogenetic virus lineages.

scientific article published in January 1993

Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy

scientific article published on October 2008

Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice

scientific article

Polyethylenimine, a cost-effective transfection reagent

scholarly article by Christina Ehrhardt published in June 2006

The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIV

scientific article

Influenza viruses control the vertebrate type I interferon system: factors, mechanisms, and consequences

scientific article published on September 2009

The influenza virus PB1-F2 protein has interferon antagonistic activity

scientific article

List of works by Stephan Ludwig

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

Caspase 3 activation is essential for efficient influenza virus propagation

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression

NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation

MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes

Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence

The stress inducer arsenite activates mitogen-activated protein kinases extracellular signal-regulated kinases 1 and 2 via a MAPK kinase 6/p38-dependent pathway

MAPKAP kinase 3pK phosphorylates and regulates chromatin association of the polycomb group protein Bmi1

Activation of NF-κB via the IκB Kinase Complex Is Both Essential and Sufficient for Proinflammatory Gene Expression in Primary Endothelial Cells

3pK, a novel mitogen-activated protein (MAP) kinase-activated protein kinase, is targeted by three MAP kinase pathways

The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors

The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

A new player in a deadly game: influenza viruses and the PI3K/Akt signalling pathway

Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)

Interplay between influenza A virus and the innate immune signaling

Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB-inhibiting activity

Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells

Rac1 and PAK1 are upstream of IKK-epsilon and TBK-1 in the viral activation of interferon regulatory factor-3.

Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase

Membrane accumulation of influenza A virus hemagglutinin triggers nuclear export of the viral genome via protein kinase Calpha-mediated activation of ERK signaling

Influenza-virus-induced signaling cascades: targets for antiviral therapy?

Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury

Phylogenetic relationship of the nonstructural (NS) genes of influenza A viruses

Viral targeting of the interferon-{beta}-inducing Traf family member-associated NF-{kappa}B activator (TANK)-binding kinase-1.

Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells

The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity

MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells

Multiple signaling pathways regulate NF-kappaB-dependent transcription of the monocyte chemoattractant protein-1 gene in primary endothelial cells

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death

Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes

Ras-independent Activation of the Raf/MEK/ERK Pathway upon Calcium-induced Differentiation of Keratinocytes

Antigenic and genetic analyses of H1N1 influenza A viruses from European pigs

European swine virus as a possible source for the next influenza pandemic?

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

Influenza virus-induced AP-1-dependent gene expression requires activation of the JNK signaling pathway

Antiviral activity of the MEK-inhibitor U0126 against pandemic H1N1v and highly pathogenic avian influenza virus in vitro and in vivo

MEK inhibition impairs influenza B virus propagation without emergence of resistant variants

Analysis of influenza A virus nucleoproteins for the assessment of molecular genetic mechanisms leading to new phylogenetic virus lineages.

Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy

Synergistic adaptive mutations in the hemagglutinin and polymerase acidic protein lead to increased virulence of pandemic 2009 H1N1 influenza A virus in mice

Polyethylenimine, a cost-effective transfection reagent

The NS segment of an H5N1 highly pathogenic avian influenza virus (HPAIV) is sufficient to alter replication efficiency, cell tropism, and host range of an H7N1 HPAIV

Influenza viruses control the vertebrate type I interferon system: factors, mechanisms, and consequences

The influenza virus PB1-F2 protein has interferon antagonistic activity