Search filters

List of works by Augustine Arukwe

2nd Norwegian Environmental Toxicology Symposium: Joining Forces for an Integrated Search for Environmental Solutions

scientific article published on 01 January 2009

A protocol and cultivation system for gnotobiotic Atlantic cod larvae (Gadus morhua L.) as a tool to study host microbe interactions

Acetylcholinesterase activity in juvenile Ciona intestinalis (Ascidiacea, Urochordata) after exposure to tributyltin

Activation of estrogen receptor signaling by the dioxin-like aryl hydrocarbon receptor agonist, 3,3',4,4',5-pentachlorobiphenyl (PCB126) in salmon in vitro system

scientific article published on 13 November 2007

Alteration of brain and interrenal StAR protein, P450scc, and Cyp11beta mRNA levels in atlantic salmon after nominal waterborne exposure to the synthetic pharmaceutical estrogen ethynylestradiol

scientific article published in April 2007

Altered hepatic retinol and CYP26 levels in adult European common frogs (Rana temporaria) exposed to p,p'-DDE.

scientific article published on 7 April 2006

Androgenic modulation of early growth of Atlantic cod (Gadus morhua L.) previtellogenic oocytes and zona radiata-related genes.

scientific article

Assessing the effects of Awba dam sediment (Nigeria) on the steroidogenesis of H295R cells using different extraction methods

scientific article published on 29 August 2018

Bacterial composition and activity determines host gene-expression responses in gnotobiotic Atlantic cod (Gadus morhua) larvae.

scientific article published on 15 January 2012

Biotransformation and Oxidative Stress Responses in Captive Nile Crocodile (Crocodylus niloticus) Exposed to Organic Contaminants from the Natural Environment in South Africa

scientific article

Biotransformation and oxidative stress responses in rat hepatic cell-line (H4IIE) exposed to organophosphate esters (OPEs)

scientific article published on 08 April 2019

Biotransformation of PCBs in Arctic seabirds: characterization of phase I and II pathways at transcriptional, translational and activity levels

scientific article published on 20 February 2010

Biotransformation of PCBs in relation to phase I and II xenobiotic-metabolizing enzyme activities in ringed seals (Phoca hispida) from Svalbard and the Baltic Sea.

scientific article published in December 2008

Biotransformation of polybrominated diphenyl ethers and polychlorinated biphenyls in beluga whale (Delphinapterus leucas) and rat mammalian model using an in vitro hepatic microsomal assay

scientific article published on 2 December 2005

Biphasic modulation of neuro- and interrenal steroidogenesis in juvenile African sharptooth catfish (Clarias gariepinus) exposed to waterborne di-(2-ethylhexyl) phthalate

scientific article

Brain cytochrome P450 aromatase gene isoforms and activity levels in atlantic salmon after waterborne exposure to nominal environmental concentrations of the pharmaceutical ethynylestradiol and antifoulant tributyltin

scientific article published on 16 February 2006

Cellular and molecular responses to endocrine-modulators and the impact on fish reproduction

scientific article

Changes in morphometry and association between whole-body fatty acids and steroid hormone profiles in relation to bioaccumulation patterns in salmon larvae exposed to perfluorooctane sulfonic or perfluorooctane carboxylic acids

scientific article published on 11 January 2013

Changes in three hepatic cytochrome P450 subfamilies during a reproductive cycle in turbot (Scophthalmus maximus L.)

scientific article published in 1997

Characterization and profiling of hepatic cytochromes P450 and phase II xenobiotic-metabolizing enzymes in beluga whales (Delphinapterus leucas) from the St. Lawrence River Estuary and the Canadian Arctic

scientific article

Comparative endocrine disruptive effects of contaminants in ringed seals (Phoca hispida) from Svalbard and the Baltic Sea.

scientific article published on June 2010

Complementary DNA cloning, sequence analysis and differential organ expression of beta-naphthoflavone-inducible cytochrome P4501A in Atlantic salmon (Salmo salar).

scholarly article

Concentration of polychlorinated biphenyl (PCB) congeners in the muscle of Clarias gariepinus and sediment from inland rivers of southwestern Nigeria and estimated potential human health consequences

scientific article

Concentrations, patterns and metabolites of organochlorine pesticides in relation to xenobiotic phase I and II enzyme activities in ringed seals (Phoca hispida) from Svalbard and the Baltic Sea.

scientific article published on 28 March 2009

Corrigendum to “Activation of estrogen receptor signaling by the dioxin-like aryl hydrocarbon receptor agonist, 3,3′,4,4′,5-pentachlorobiphenyl (PCB126) in salmon in vitro system” [Toxicology and Applied Pharmacology 227 (2008) 313–324]

scholarly article by Anne Skjetne Mortensen & Augustine Arukwe published February 2011 in Toxicology and Applied Pharmacology

Corrigendum to “Estrogenic effect of dioxin-like aryl hydrocarbon receptor (AhR) agonist (PCB congener 126) in salmon hepatocytes” [Marine Environmental Research 66 (2008) 119–120]

scholarly article published in Marine Environmental Research

Detection and occurrence of microplastics in the stomach of commercial fish species from a municipal water supply lake in southwestern Nigeria

scientific article published on 12 May 2020

Detection of vitellogenin and zona radiata protein expressions in surface mucus of immature juvenile Atlantic salmon (Salmo salar) exposed to waterborne nonylphenol

scientific article published in June 2005

Developmental alterations and endocrine-disruptive responses in farmed Nile crocodiles (Crocodylus niloticus) exposed to contaminants from the Crocodile River, South Africa

scientific article published on 6 January 2016

Developmental effects related to angiogenesis and osteogenic differentiation in Salmon larvae continuously exposed to dioxin-like 3,3',4,4'-tetrachlorobiphenyl (congener 77).

scientific article published on 16 September 2011

Differential biomarker gene and protein expressions in nonylphenol and estradiol-17beta treated juvenile rainbow trout (Oncorhynchus mykiss).

scientific article published in May 2001

Differential modulation of neuro- and interrenal steroidogenesis of juvenile salmon by the organophosphates - tris(2-butoxyethyl)- and tris(2-cloroethyl) phosphate

scientific article

Differential organ expression patterns of thyroid hormone receptor isoform genes in p,p′-DDE-treated adult male common frog, Rana temporaria

scientific article published on July 11, 2005

Dimethyl sulfoxide is a potent modulator of estrogen receptor isoforms and xenoestrogen biomarker responses in primary culture of salmon hepatocytes

scientific article published on 3 June 2006

Effect of reduced food intake on toxicokinetics of halogenated organic contaminants in herring gull (Larus argentatus) chicks

scientific article

Effects of 17alpha-ethynylestradiol on hormonal responses and xenobiotic biotransformation system of Atlantic salmon (Salmo salar).

scientific article published on 17 August 2007

Effects of 17alpha-methyltestosterone exposure on steroidogenesis and cyclin-B mRNA expression in previtellogenic oocytes of Atlantic cod (Gadus morhua).

scientific article published on 17 July 2007

Effects of 2,4,6-trinitrotoluene (TNT) on phase I and phase II biotransformation enzymes in European eel Anguilla anguilla (Linnaeus, 1758).

scientific article published on 26 February 2008

Effects of Diisodecyl Phthalate on PPAR:RXR-Dependent Gene Expression Pathways in Sea Bream Hepatocytes

scientific article published on 15 April 2015

Effects of dopamine 2 receptor antagonist on sex steroid levels, oocyte maturation and spawning performances in Waigieu seaperch (Psammoperca waigiensis)

scientific article published on August 22, 2012

Effects of elevated dissolved carbon dioxide and perfluorooctane sulfonic acid, given singly and in combination, on steroidogenic and biotransformation pathways of Atlantic cod.

scientific article

Effects of hydroxy-polychlorinated biphenyl (OH-PCB) congeners on the xenobiotic biotransformation gene expression patterns in primary culture of Atlantic salmon (Salmo salar) hepatocytes

article

Effects of tributyltin (TBT) on in vitro hormonal and biotransformation responses in Atlantic salmon (Salmo salar).

scientific article published in January 2009

Effects of tributyltin on salmon interrenal CYP11β, steroidogenic factor-1 and glucocorticoid receptor transcripts in the presence and absence of second messenger activator, forskolin.

scientific article published in February 2010

Effects of xenoestrogen treatment on zona radiata protein and vitellogenin expression in Atlantic salmon (Salmo salar).

scientific article

Effects on development, growth responses and thyroid-hormone systems in eyed-eggs and yolk-sac larvae of Atlantic salmon (Salmo salar) continuously exposed to 3,3',4,4'-tetrachlorobiphenyl (PCB-77).

scientific article published in January 2014

Eggshell and egg yolk proteins in fish: hepatic proteins for the next generation: oogenetic, population, and evolutionary implications of endocrine disruption

scientific article

Endocrine and developmental effects in Atlantic salmon (Salmo salar) exposed to perfluorooctane sulfonic or perfluorooctane carboxylic acids

scientific article published on 4 August 2011

Endocrine, biotransformation, and oxidative stress responses in salmon hepatocytes exposed to chemically induced hypoxia and perfluorooctane sulfonamide (PFOSA), given singly or in combination

scientific article

Endocrine-disruptor molecular responses, occurrence of intersex and gonado-histopathological changes in tilapia species from a tropical freshwater dam (Awba Dam) in Ibadan, Nigeria

scientific article

Environmental occurrence and biota concentration of phthalate esters in Epe and Lagos Lagoons, Nigeria

scientific article

Erratum to ‘In vivo and in vitro metabolism and organ distribution of nonylphenol in Atlantic salmon (Salmo salar)’

scholarly article published in Aquatic Toxicology

Estrogen receptor-hijacking by dioxin-like 3,3'4,4',5-pentachlorobiphenyl (PCB126) in salmon hepatocytes involves both receptor activation and receptor protein stability

scientific article

Estrogenic effect of dioxin-like aryl hydrocarbon receptor (AhR) agonist (PCB congener 126) in salmon hepatocytes

scientific article published on 26 February 2008

Estrogenic effects of selected hydroxy polychlorinated biphenyl congeners in primary culture of Atlantic Salmon (Salmo salar) hepatocytes

scientific article

Fish condition factor, peroxisome proliferator activated receptors and biotransformation responses in Sarotherodon melanotheron from a contaminated freshwater dam (Awba Dam) in Ibadan, Nigeria

scientific article

Fish model for assessing the in vivo estrogenic potency of the mycotoxin zearalenone and its metabolites

scientific article published on 01 September 1999

Fish zona radiata (eggshell) protein: a sensitive biomarker for environmental estrogens

scientific article published on April 1997

Food restriction in young Japanese quails: effects on growth, metabolism, plasma thyroid hormones and mRNA species in the thyroid hormone signalling pathway

scientific article published in October 2009

Gene expression patterns in estrogen (nonylphenol) and aryl hydrocarbon receptor agonists (PCB-77) interaction using rainbow trout (Oncorhynchus Mykiss) primary hepatocyte culture

scientific article

Genomic approach in evaluating the role of androgens on the growth of Atlantic cod (Gadus morhua) previtellogenic oocytes.

scientific article

Gonado-histopathological changes, intersex and endocrine disruptor responses in relation to contaminant burden in Tilapia species from Ogun River, Nigeria.

scientific article published on 31 August 2016

Gross pathology, physiological and toxicological responses in relation to metals and persistent organic pollutants (POPs) burden in tilapia species from Ogun River, Nigeria

scientific article published on 8 June 2017

Hepatic biotransformation and metabolite profile during a 2-week depuration period in Atlantic salmon fed graded levels of the synthetic antioxidant, ethoxyquin.

scientific article

Hepatic biotransformation responses in Atlantic salmon exposed to retinoic acids and 3,3',4,4'-tetrachlorobiphenyl (PCB congener 77).

scientific article published on 19 February 2008

Hepatic metabolism, phase I and II biotransformation enzymes in Atlantic salmon (Salmo Salar, L) during a 12 week feeding period with graded levels of the synthetic antioxidant, ethoxyquin.

scientific article

Hepatic phase I and II biotransformation responses and contaminant exposure in long-finned pilot whales from the Northeastern Atlantic

scientific article published on 19 December 2017

Hepatic retention and toxicological responses during feeding and depuration periods in Atlantic salmon ( Salmo salar ) fed graded levels of the synthetic antioxidant, butylated hydroxytoluene.

scientific article

Hormone, vitamin and contaminant status during the moulting/fasting period in ringed seals (Pusa [Phoca] hispida) from Svalbard

scientific article published on 2 October 2009

Immune-regulatory transcriptional responses in multiple organs of Atlantic salmon after tributyltin exposure, alone or in combination with forskolin.

scientific article

In vivo and in vitro metabolism and organ distribution of nonylphenol in Atlantic salmon (Salmo salar)

scientific article published on 01 July 2000

In vivo modulation of nonylphenol-induced zonagenesis and vitellogenesis by the antiestrogen, 3,3'4,4'-tetrachlorobiphenyl (PCB-77) in juvenile fish

scientific article published in June 2001

Induction of hepatic estrogen receptor in juvenile Atlantic salmon in vivo by the environmental estrogen, 4-nonylphenol

scientific article published on 01 August 1999

Interactions between estrogen- and Ah-receptor signalling pathways in primary culture of salmon hepatocytes exposed to nonylphenol and 3,3',4,4'-tetrachlorobiphenyl (congener 77).

scientific article published on 13 April 2007

Interactions of 2,4,6-trinitrotoluene (TNT) with xenobiotic biotransformation system in European eel Anguilla anguilla (Linnaeus, 1758).

scientific article published on 14 April 2008

Intersex and alterations in reproductive development of a cichlid, Tilapia guineensis, from a municipal domestic water supply lake (Eleyele) in Southwestern Nigeria

scientific article

Investigations on the Metabolism and Potentially Adverse Effects of Ethoxyquin Dimer, a Major Metabolite of the Synthetic Antioxidant Ethoxyquin in Salmon Muscle

scientific article published on 01 September 2011

Levels, Patterns, and Biomagnification Potential of Perfluoroalkyl Substances in a Terrestrial Food Chain in a Nordic Skiing Area

scientific article published on 06 November 2019

Lipid peroxidation and oxidative stress responses in juvenile salmon exposed to waterborne levels of the organophosphate compounds tris(2-butoxyethyl)- and tris(2-chloroethyl) phosphates

scientific article published on January 2016

Lipid peroxidation and oxidative stress responses of salmon fed a diet containing perfluorooctane sulfonic- or perfluorooctane carboxylic acids

scientific article

Metabolism and organ distribution of nonylphenol in Atlantic salmon (Salmo salar)

scientific article published on 01 July 2000

Mitochondrial DNA inference between European populations of Tanymastix stagnalis and their glacial survival in Scandinavia

scientific article (publication date: October 2013)

Mixtures of chemical pollutants at European legislation safety concentrations: how safe are they?

scientific article

Modulation of Neuro-Dopamine Homeostasis in Juvenile Female Atlantic Cod ( Gadus morhua) Exposed to Polycyclic Aromatic Hydrocarbons and Perfluoroalkyl Substances

scientific article published on 29 May 2019

Modulation of acute steroidogenesis, peroxisome proliferator-activated receptors and CYP3A/PXR in salmon interrenal tissues by tributyltin and the second messenger activator, forskolin.

scientific article published on 6 March 2010

Modulation of brain steroidogenesis by affecting transcriptional changes of steroidogenic acute regulatory (StAR) protein and cholesterol side chain cleavage (P450scc) in juvenile Atlantic salmon (Salmo salar) is a novel aspect of nonylphenol toxici

scientific article published in December 2005

Modulation of membrane lipid composition and homeostasis in salmon hepatocytes exposed to hypoxia and perfluorooctane sulfonamide, given singly or in combination

scientific article

Modulation of salmon ovarian steroidogenesis and growth factor responses by the xenoestrogen, 4-nonylphenol

scientific article published on 22 August 2009

Modulation of steroidogenesis and xenobiotic biotransformation responses in zebrafish (Danio rerio) exposed to water-soluble fraction of crude oil.

scientific article published on 8 April 2008

Modulation of xenobiotic biotransformation system and hormonal responses in Atlantic salmon (Salmo salar) after exposure to tributyltin (TBT)

article

Molecular and biochemical biomarkers in environmental monitoring: A comparison of biotransformation and antioxidant defense systems in multiple tissues

scientific article published on June 23, 2011

Molecular and cellular detection of expression of vitellogenin and zona radiata protein in liver and skin of juvenile salmon (Salmo salar) exposed to nonylphenol

scientific article published on 21 December 2007

Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17beta-estradiol- and nonylphenol-treated fish

scholarly article

Molecular ontogenesis of digestive capability and associated endocrine control in Atlantic cod (Gadus morhua) larvae

scientific article published on 12 June 2011

Municipal landfill leachates: a significant source for new and emerging pollutants

scientific article published on 8 August 2010

Neural aromatase transcript and protein levels in Atlantic salmon (Salmo salar) are modulated by the ubiquitous water pollutant, 4-nonylphenol

scientific article published on 23 May 2009

Novel aspects of uptake patterns, metabolite formation and toxicological responses in Salmon exposed to the organophosphate esters-Tris(2-butoxyethyl)- and tris(2-chloroethyl) phosphate

scientific article published on 30 January 2018

Occurrence, Species, and Organ Differences in Bioaccumulation Patterns of Phthalate Esters in Municipal Domestic Water Supply Lakes in Ibadan, Nigeria

scientific article published on January 2015

Organ-specific patterns of P450arom gene isoforms are modulated by p,p'-DDE in adult male European common frog, Rana temporaria

scientific article published on 18 April 2006

Perfluorooctane sulfonamide-mediated modulation of hepatocellular lipid homeostasis and oxidative stress responses in Atlantic salmon hepatocytes

scientific article published on 31 May 2012

Peroxisome proliferator-activated receptors and biotransformation responses in relation to condition factor and contaminant burden in tilapia species from Ogun River, Nigeria

scientific article published on 29 December 2015

Peroxisome proliferator-activated receptors, estrogenic responses and biotransformation system in the liver of salmon exposed to tributyltin and second messenger activator

scientific article published on 24 April 2010

Persistent sex-reversal and oviducal agenesis in adult Xenopus (Silurana) tropicalis frogs following larval exposure to the environmental pollutant ethynylestradiol

scientific article published on 14 July 2006

Preliminary identification and quantification of steroid hormones in the red palm weevil, Rhynchophorus ferrugineus

Previtellogenic oocyte growth and transcriptional changes of steroidogenic enzyme genes in immature female Atlantic cod (Gadus morhua L.) after exposure to the androgens 11-ketotestosterone and testosterone.

scientific article published on 13 November 2008

Recombinant albumin and transthyretin transport proteins from two gull species and human: chlorinated and brominated contaminant binding and thyroid hormones

scientific article published in January 2010

Recombinant transthyretin purification and competitive binding with organohalogen compounds in two gull species (Larus argentatus and Larus hyperboreus).

scientific article published on 25 November 2008

Regio-specific hydroxylation of nonylphenol and the involvement of CYP2K- and CYP2M-like iso-enzymes in Atlantic salmon (Salmo salar).

scientific article published in February 2002

Reproductive cycle in female Waigieu seaperch (Psammoperca waigiensis) reared under different salinity levels and the effects of dopamine antagonist on steroid hormone levels

scholarly article by Hung Quoc Pham et al published February 2010 in Journal of Experimental Marine Biology and Ecology

Salmon Eggshell Protein Expression: A Marker for Environmental Estrogens

scientific article

Screening of ovarian steroidogenic pathway in Ciona intestinalis and its modulation after tributyltin exposure

scientific article published on 7 March 2010

Solid waste deposits as a significant source of contaminants of emerging concern to the aquatic and terrestrial environments - a developing country case study from Owerri, Nigeria

scientific article published on 11 September 2012

Steroidogenic acute regulatory (StAR) protein and cholesterol side-chain cleavage (P450scc) as molecular and cellular targets for 17alpha-ethynylestradiol in salmon previtellogenic oocytes

scientific article published on 15 November 2007

Steroidogenic acute regulatory (StAR) protein and cholesterol side-chain cleavage (P450scc)-regulated steroidogenesis as an organ-specific molecular and cellular target for endocrine disrupting chemicals in fish

scientific article published on 9 April 2008

Targeted salmon gene array (SalArray): a toxicogenomic tool for gene expression profiling of interactions between estrogen and aryl hydrocarbon receptor signalling pathways

scientific article

The effects on steroidogenesis and histopathology of adult male Japanese quails (Coturnix coturnix japonica) testis following pre-pubertal exposure to di(n-butyl) phthalate (DBP).

scientific article published on 28 June 2014

The environmental estrogen, 4-nonylphenol modulates brain estrogen-receptor- and aromatase (CYP19) isoforms gene expression patterns in Atlantic salmon (Salmo salar).

scientific article

The expression of CYP1A, vitellogenin and zona radiata proteins in Atlantic salmon (Salmo salar) after oral dosing with two commercial PBDE flame retardant mixtures: absence of short-term responses

scientific article published in September 2002

The in vivo effect of combinations of octylphenol, butylbenzylphthalate and estradiol on liver estradiol receptor modulation and induction of zona radiata proteins in rainbow trout: no evidence of synergy

scholarly article by F.R. Knudsen et al published October 1998 in Environmental Pollution

The influence of dietary constituents on the molecular ontogeny of digestive capability and effects on growth and appetite in Atlantic cod larvae (Gadus morhua)

The intersex phenomenon in Sarotherodon melanotheron from Lagos lagoon (Nigeria): Occurrence and severity in relation to contaminants burden in sediment

The persistent DDT metabolite, 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene, alters thyroid hormone-dependent genes, hepatic cytochrome P4503A, and pregnane X receptor gene expressions in Atlantic salmon (Salmo salar) Parr

scientific article published in June 2006

The xenoestrogen 4-nonylphenol modulates hepatic gene expression of pregnane X receptor, aryl hydrocarbon receptor, CYP3A and CYP1A1 in juvenile Atlantic salmon (Salmo salar).

scientific article published on 6 January 2006

The xenoestrogen, 4-nonylphenol, impaired steroidogenesis in previtellogenic oocyte culture of Atlantic cod (Gadus morhua) by targeting the StAR protein and P450scc expressions

scientific article published on 4 December 2006

Thyroid hormone-dependent gene expression as a biomarker of short-term 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) exposure in European common frog (Rana temporaria) tadpoles

scientific article published in November 2006

Tissue bioaccumulation patterns, xenobiotic biotransformation and steroid hormone levels in Atlantic salmon (Salmo salar) fed a diet containing perfluoroactane sulfonic or perfluorooctane carboxylic acids

scientific article published on 26 February 2011

Toxicological housekeeping genes: do they really keep the house?

scientific article published in December 2006

Transcriptional and catalytic responses of antioxidant and biotransformation pathways in mussels, Mytilus galloprovincialis, exposed to chemical mixtures.

scientific article

Transcriptional modulation of brain and hepatic estrogen receptor and P450arom isotypes in juvenile Atlantic salmon (Salmo salar) after waterborne exposure to the xenoestrogen, 4-nonylphenol

scientific article published on 4 January 2006

Two strategies to unravel gene expression responses of host-microbe interactions in cod (Gadus morhua) larvae

article