Search filters

List of works by Lars Larsson

A Proteomic Approach to Identify Alterations in the Small Ubiquitin-like Modifier (SUMO) Network during Controlled Mechanical Ventilation in Rat Diaphragm Muscle

scientific article

A myopathy-linked tropomyosin mutation severely alters thin filament conformational changes during activation

scientific article

A novel type of delayed tension reduction observed in rat motor units after intense activity

scientific article published on 01 May 1989

A porcine model of acute quadriplegic myopathy: a feasibility study

scientific article published on 25 August 2006

A technique for studies of the contractile apparatus in single human muscle fibre segments obtained by percutaneous biopsy

scientific article published on 01 December 1992

Aberrant expression of myosin isoforms in skeletal muscles from mice lacking the rev-erbAalpha orphan receptor gene

scientific article published on 16 September 2004

Aberrant post-translational modifications compromise human myosin motor function in old age.

scientific article

Actomyosin interactions in a novel single muscle fiber in vitro motility assay

scientific article published on 01 May 2000

Acute and severe trabecular bone loss in a rat model of critical illness myopathy

scientific article published on 24 August 2021

Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: Mechanisms at the cellular and molecular levels

scientific article published on 01 January 2000

Acute quadriplegic myopathy following autologous peripheral blood stem cell transplantation for breast cancer

scientific article published on 01 April 1999

Acute quadriplegic myopathy: an acquired "myosinopathy"

scientific article published on 01 January 2008

Adaptation by alternative RNA splicing of slow troponin T isoforms in type 1 but not type 2 Charcot-Marie-Tooth disease

scientific article

Adjusting data to body size: a comparison of methods as applied to quantitative trait loci analysis of musculoskeletal phenotypes

scientific article

Age related differences in diaphragm muscle fiber response to mid/long term controlled mechanical ventilation

scientific article published on 25 June 2014

Age-related abnormalities in regulation of the ryanodine receptor in rat fast-twitch muscle

scientific article published on 01 January 1996

Age-related changes in contractile properties and expression of myosin isoforms in single skeletal muscle cells

scientific article published on 01 January 1997

Aging, muscle fiber type, and contractile function in sprint-trained athletes

scientific article published on 11 May 2006

Aging-related changes in skeletal muscle. Mechanisms and interventions.

scientific article

Alterations in muscle proteome of patients diagnosed with amyotrophic lateral sclerosis.

scientific article

An age-related type IIB to IIX myosin heavy chain switching in rat skeletal muscle

article by Lars Larsson et al published 1 February 1993 in Acta Physiologica Scandinavica

An electrophysiological method for monitoring blood flow in skeletal muscle. An experimental study in the rat.

scientific article published in January 1989

An overview of carbohydrate-protein interactions with specific reference to myosin and ageing

scientific article

Anomaly of anatomical origin of soleus muscle: a mouse model.

scientific article

Application of skinned single muscle fibres to determine myofilament function in ageing and disease.

scientific article published in January 2007

Bed rest increases the amount of mismatched fibers in human skeletal muscle

scientific article published on 01 February 1999

Blood pressure and heart rate QTL in mice of the B6/D2 lineage: sex differences and environmental influences

scientific article published on 09 December 2008

Bone, muscle, and physical activity: structural equation modeling of relationships and genetic influence with age.

scientific article published on September 2009

Changes in myosin structure and function in response to glycation.

scientific article

Chaperone co-inducer BGP-15 mitigates early contractile dysfunction of the soleus muscle in a rat ICU model

scientific article published on 18 December 2019

Coherence of EMG activity and single motor unit discharge patterns in human rhythmical force production

scientific article published in March 2005

Comprehensive analysis of tropomyosin isoforms in skeletal muscles by top-down proteomics.

scientific article published on 18 April 2016

Contractile properties in single muscle fibres from chronically overused motor units in relation to motoneuron firing properties in prior polio patients

scientific article published in October 1995

Contractile properties, fatiguability and glycolytic metabolism in fast- and slow-twitch rat skeletal muscles of various temperatures.

scientific article

Contractile studies of single human skeletal muscle fibers: a comparison of different muscles, permeabilization procedures, and storage techniques

scientific article published on 01 August 1997

Contractility and myosin isoform compositions of skeletal muscles and muscle cells from rats treated with thyroid hormone for 0, 4 and 8 weeks

scientific article published on 01 June 1997

Defective regulation of contractile function in muscle fibres carrying an E41K beta-tropomyosin mutation

scientific article published on 17 April 2008

Detection of an aging-related increase in advanced glycation end products in fast- and slow-twitch skeletal muscles in the rat.

scientific article

Diaphragm muscle weakness in an experimental porcine intensive care unit model

scientific article

Disrupted myosin cross-bridge cycling kinetics triggers muscle weakness in nebulin-related myopathy.

scientific article published on 24 February 2011

Dissecting human skeletal muscle troponin proteoforms by top-down mass spectrometry

scientific article published on 23 January 2015

EMD 57033 partially reverses ventilator-induced diaphragm muscle fibre calcium desensitisation

scientific article published on 02 October 2009

Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits

scientific article published on 6 March 2012

Effective top-down LC/MS+ method for assessing actin isoforms as a potential cardiac disease marker

scientific article published on 19 July 2015

Effects of a R133W beta-tropomyosin mutation on regulation of muscle contraction in single human muscle fibres

scientific article

Effects of a preferential myosin loss on Ca2+ activation of force generation in single human skeletal muscle fibres

scientific article published on 01 February 2008

Effects of age and gender on shortening velocity and myosin isoforms in single rat muscle fibres

scientific article published in May 1998

Effects of age on calcium transport activity of sarcoplasmic reticulum in fast- and slow-twitch rat muscle fibres

scientific article published in December 1989

Effects of age on contractile and enzyme-histochemical properties of fast- and slow-twitch single motor units in the rat

scientific article published on 01 November 1987

Effects of age on enzyme-histochemical fibre spectra and contractile properties of fast- and slow-twitch skeletal muscles in the rat.

scientific article

Effects of age on physiological, immunohistochemical and biochemical properties of fast-twitch single motor units in the rat

scientific article published on 01 November 1991

Effects of age on sarcoplasmic reticulum properties and histochemical composition of fast- and slow-twitch rat muscles

scientific article published on 01 May 1995

Effects of age on the motor unit. A study on single motor units in the rat

scientific article published on 01 January 1988

Effects of ageing and gender on contractile properties in human skeletal muscle and single fibres

scientific article published on 01 July 2007

Effects of ageing on enzyme-histochemical, morphometrical and contractile properties of the soleus muscle in the rat.

scientific article published in October 1989

Effects of ageing on the motor unit.

scientific article

Effects of aging and gender on the spatial organization of nuclei in single human skeletal muscle cells.

scientific article published on 21 July 2010

Effects of aging on actin sliding speed on myosin from single skeletal muscle cells of mice, rats, and humans

scientific article published in April 2001

Effects of aging on force variability, single motor unit discharge patterns, and the structure of 10, 20, and 40 Hz EMG activity

scientific article published on 01 January 2003

Effects of aging on human skeletal muscle myosin heavy-chain mRNA content and protein isoform expression

scientific article published in June 2002

Effects of aging on regulation of muscle contraction at the motor unit, muscle cell, and molecular levels

scientific article

Effects of aging on shortening velocity and myosin isoform composition in single human skeletal muscle cells

scientific article published on 01 February 1997

Effects of chronic nicotine exposure on contractile enzyme-histochemical and biochemical properties of fast- and slow-twitch skeletal muscles in the rat

scientific article published on 01 December 1988

Effects of combined strength and sprint training on regulation of muscle contraction at the whole-muscle and single-fibre levels in elite master sprinters.

scientific article

Effects of corticosteroids in the development of limb muscle weakness in a porcine intensive care unit model

scientific article published on 19 February 2013

Effects of denervation on enzyme-histochemical and morphometrical properties of the rat soleus muscle in relation to age

scientific article published on 01 June 1990

Effects of long-term physical training and detraining on enzyme histochemical and functional skeletal muscle characteristic in man.

scientific article published in October 1985

Effects of removal of weight-bearing function on contractility and myosin isoform composition in single human skeletal muscle cells

scientific article published in June 1996

Effects of the interval between removal and freezing of muscle biopsies on muscle fibre size

scientific article published in May 1988

Effects of thyroid hormone on fast- and slow-twitch skeletal muscles in young and old rats

scientific article published on 01 November 1994

Effects of thyroid hormone receptor gene disruption on myosin isoform expression in mouse skeletal muscles

scientific article published in June 2000

Excitability in free muscle transfers: an optimal method of monitoring tissue circulation?

scientific article published on 01 December 1986

Experimental animal models of muscle wasting in intensive care unit patients.

scientific article published on September 2007

Factors underlying the early limb muscle weakness in acute quadriplegic myopathy using an experimental ICU porcine model

scientific article

Fatigue of chronically overused motor units in prior polio patients

scientific article published on 01 June 1996

Fibre type-specific increase in passive muscle tension in spinal cord-injured subjects with spasticity

scientific article published on 24 August 2006

Firing rate of the lower motoneuron and contractile properties of its muscle fibers after upper motoneuron lesion in man

scientific article published on 01 August 1997

Force-generating capacity of human myosin isoforms extracted from single muscle fibre segments

scientific article published on 25 October 2010

Gender- and age-related differences in the regulatory influence of thyroid hormone on the contractility and myosin composition of single rat soleus muscle fibres

scientific article published in December 1998

Gender- and thyroid hormone-related transitions of essential myosin light chain isoform expression in rat soleus muscle during ageing

scientific article

Gender-related differences in the regulatory influence of thyroid hormone on the expression of myosin isoforms in young and old rats

scientific article published in January 1997

Gene expression and muscle fiber function in a porcine ICU model

scientific article published on 25 August 2009

Genetic architecture of fast- and slow-twitch skeletal muscle weight in 200-day-old mice of the C57BL/6J and DBA/2J lineage

scientific article published on 16 December 2003

Genetic determinants of weight of fast- and slow-twitch skeletal muscle in 500-day-old mice of the C57BL/6J and DBA/2J lineage

scientific article published in February 2005

Genetic determinants of weight of fast- and slow-twitch skeletal muscles in old mice

scientific article published on 12 June 2006

Glutathione reverses early effects of glycation on myosin function

scientific article published on 30 April 2003

Histochemical and biochemical changes in human skeletal muscle with age in sedentary males, age 22--65 years

scientific article published on May 1978

Histochemical characteristics of human skeletal muscle during aging

scientific article published on 01 March 1983

Hormone replacement therapy improves contractile function and myonuclear organization of single muscle fibres from postmenopausal monozygotic female twin pairs.

scientific article

Human single masseter muscle fibers contain unique combinations of myosin and myosin binding protein C isoforms

scientific article published in January 2002

Human skeletal muscle myosin function at physiological and non-physiological temperatures

scientific article published on 01 February 2006

Impact of post-synaptic block of neuromuscular transmission, muscle unloading and mechanical ventilation on skeletal muscle protein and mRNA expression

scientific article published on 26 July 2006

Impact of temperature on growth and metabolic efficiency of Penicillium roqueforti--correlations between produced heat, ergosterol content and biomass

scientific article published on 4 February 2009

Impaired Ca(2+) release contributes to muscle weakness in a rat model of critical illness myopathy

scientific article published on 10 August 2016

Impaired autophagy, chaperone expression, and protein synthesis in response to critical illness interventions in porcine skeletal muscle

scientific article published on 09 April 2013

In vitro motility speed of slow myosin extracted from single soleus fibres from young and old rats

scientific article

Increased cell death and delayed development in the cerebellum of mice lacking the rev-erbA(alpha) orphan receptor.

scientific article published in April 2000

Increasing intravenous glucose load in the presence of normoglycemia: effect on outcome and metabolism in critically ill rabbits

scientific article published in February 2010

Influence of the interval between removal and freezing of muscle samples on muscle fibre size with special reference to sample size and fibre type

scientific article published in July 1990

Is functional hypertrophy and specific force coupled with the addition of myonuclei at the single muscle fiber level?

scientific article published on 28 November 2011

Is the motor unit uniform?

scientific article published in February 1992

Isometric and dynamic endurance as a function of age and skeletal muscle characteristics

scientific article published on October 1978

Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor alpha1.

scientific article

Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness

scientific article

Lower limb skeletal muscle function after 6 wk of bed rest

scientific article published on 01 January 1997

Maintenance of muscle mass, fiber size, and contractile function in mice lacking the Z-disc protein myotilin

scientific article

Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin

scientific article published on 08 September 2020

Masseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model

scientific article

Maximum shortening velocity and myosin isoforms in single muscle fibers from young and old rats

scientific article published on 01 January 1996

Mechanical Signaling in the Pathophysiology of Critical Illness Myopathy

scientific article

Mechanisms underlying ICU muscle wasting and effects of passive mechanical loading

scientific article published on 26 October 2012

Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model

scientific article published on 18 October 2011

Mechano-signalling pathways in an experimental intensive critical illness myopathy model

scientific article

Morphological and functional characteristics of the ageing skeletal muscle in man. A cross-sectional study

scientific article published on January 1, 1978

Morphological muscle characteristics in rowers

scientific article published on 01 December 1980

Motoneuron and muscle fiber properties of remaining motor units in weak tibialis anterior muscles in prior polio

scientific article published on 01 May 1995

Motor unit fibre density in extremely hypertrophied skeletal muscles in man. Electrophysiological signs of muscle fibre hyperplasia.

scientific article

Motor units: remodeling in aged animals

scientific article published on November 1995

Muscle atrophy and preferential loss of myosin in prolonged critically ill patients

scientific article published in January 2012

Muscle cell and motor protein function in patients with a IIa myosin missense mutation (Glu-706 to Lys)

scientific article

Muscle contractility and cell motility

scientific article published on 24 February 2012

Muscle glycogen depletion and lactate concentration during downhill skiing

scientific article published on 01 January 1978

Muscle hypertrophy in bodybuilders.

scientific article

Muscle strength and fiber composition in athletes and sedentary men.

scientific article

Muscle strength and speed of movement in relation to age and muscle morphology

scientific article published on March 1979

Muscle wasting and the temporal gene expression pattern in a novel rat intensive care unit model

scientific article

Muscle-specific differences in expression and phosphorylation of the Janus kinase 2/Signal Transducer and Activator of Transcription 3 following long-term mechanical ventilation and immobilization in rats

scientific article published on 15 October 2017

Myofibrillar protein and gene expression in acute quadriplegic myopathy

scientific article

Myonuclear domain size and myosin isoform expression in muscle fibres from mammals representing a 100,000-fold difference in body size

scientific article published on 26 September 2008

Nanometric features of myosin filaments extracted from a single muscle fiber to uncover the mechanisms underlying organized motility

scientific article published on 23 June 2015

Oxidative proteome alterations during skeletal muscle ageing

scientific article published on 3 June 2015

Paramyotonia congenita (Eulenburg): clinical, neurophysiological and muscle biopsy observations in a Swedish family

scientific article published on 01 January 1993

Physical training effects on muscle morphology in sedentary males at different ages

scientific article published on 01 January 1982

Post-operative effects on insulin resistance and specific tension of single human skeletal muscle fibres

scientific article published on 01 October 1999

Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: underlying mechanisms

scientific article published on 14 February 2011

Quantitative and qualitative morphological properties of the soleus motor nerve and the L5 ventral root in young and old rats. Relation to the number of soleus muscle fibers

scientific article published on 01 May 1990

RNA-sequencing reveals altered skeletal muscle contraction, E3 ligases, autophagy, apoptosis, and chaperone expression in patients with critical illness myopathy

Regional differences in the influence of the interval between removal and freezing of muscle samples on muscle fibre size

scientific article published in December 1991

Regulation of human muscle contraction at the cellular and molecular levels.

scientific article

Relationship between in vivo muscle force at different speeds of isokinetic movements and myosin isoform expression in men and women

scientific article

Reply from Lars Larsson, Nicola Cacciani and Barry Dworkin

scientific article published on August 2015

Role of sepsis in the development of limb muscle weakness in a porcine intensive care unit model

scientific article

Sarcopenia: Aging-Related Loss of Muscle Mass and Function

scientific article published on 01 January 2019

Scaling of skeletal muscle shortening velocity in mammals representing a 100,000-fold difference in body size.

scientific article published on 7 December 2005

Signalling pathways regulating muscle mass in ageing skeletal muscle: the role of the IGF1-Akt-mTOR-FoxO pathway.

scientific article published on 19 May 2013

Skeletal muscle metabolism and ultrastructure in relation to age in sedentary men

scientific article published on 01 November 1978

Skeletal muscle metabolism, morphology and function in sedentary smokers and nonsmokers

scientific article published on 01 September 1979

Skeletal muscle morphology, metabolism and function in smokers and non-smokers. A study on smoking-discordant monozygous twins

scientific article published on 01 March 1984

Sparing of muscle mass and function by passive loading in an experimental intensive care unit model

scientific article published on 24 December 2012

Spatial distribution of motor unit fibres in fast- and slow-twitch rat muscles with special reference to age

scientific article published on 01 November 1991

Spawning induces a shift in energy metabolism from glucose to lipid in rainbow trout white muscle

scientific article published on 01 December 1995

Structural and functional effects of mechanical ventilation and aging on single rat diaphragm muscle fibers

scientific article published on 16 March 2015

TRs have common and isoform-specific functions in regulation of the cardiac myosin heavy chain genes

scientific article published in December 2001

Targeting Heat Shock Proteins Mitigates Ventilator Induced Diaphragm Muscle Dysfunction in an Age-Dependent Manner

scientific article published on 27 September 2016

The Effect of Nutritional Status in the Pathogenesis of Critical Illness Myopathy (CIM)

scientific article

The Sick and the Weak: Neuropathies/Myopathies in the Critically Ill.

scientific article

The age‐related motor disability: underlying mechanisms in skeletal muscle at the motor unit, cellular and molecular level ⬇️

scientific article published on 01 July 1998

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass.

scientific article published on 21 October 2013

The chaperone co-inducer BGP-15 alleviates ventilation-induced diaphragm dysfunction

scientific article published in August 2016

The effect of age on in vitro motility speed of slow myosin extracted from single rat soleus fibres

scientific article

The effect of excessive weight loss on skeletal muscle in man. A study of obese patients following gastroplasty

scientific article published in May 1991

The influence of thyroid hormone on myosin isoform composition and shortening velocity of single skeletal muscle fibres with special reference to ageing and gender

scientific article

The significance of muscle fibre composition to human performance capacity

scientific article published on January 1978

There is no slowing of motility speed with increased body size in rat, human, horse and rhinoceros independent on temperature and skeletal muscle myosin isoform

scientific article published on 7 May 2011

Thyroid hormone effects on contractility and myosin composition of soleus muscle and single fibres from young and old rats

scientific article published on 01 July 1996

Thyroid hormone regulation of myosin heavy chain isoform composition in young and old rats, with special reference to IIX myosin

article

Time course analysis of mechanical ventilation-induced diaphragm contractile muscle dysfunction in the rat.

scientific article

Time-dependent structure in the discharge rate of human motor units

scientific article published on 01 August 2002

Torque-velocity relations in the quadriceps muscle of smoking-discordant twins with different fibre type proportions

Transcription factors in muscle atrophy caused by blocked neuromuscular transmission and muscle unloading in rats

scientific journal article

Uncoordinated expression of myosin heavy chains and myosin-binding protein C isoforms in human extraocular muscles

scientific article published on 01 October 2006

Vamorolone treatment improves skeletal muscle outcome in a critical illness myopathy rat model

scientific article published on 06 September 2018

What determines myonuclear domain size?

scientific article

[Drug induced tetraparesis and loss of myosin. Mild types are probably overlooked]

scientific article published on 01 June 1996

Paulina is supported by:

About Paulina

Help