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List of works by Natalia Y. Kedishvili

13-cis-retinoic acid competitively inhibits 3 alpha-hydroxysteroid oxidation by retinol dehydrogenase RoDH-4: a mechanism for its anti-androgenic effects in sebaceous glands?

scientific article

A new family of protein kinases--the mitochondrial protein kinases.

scientific article published on January 1995

A specific inhibitor of ALDH1A3 regulates retinoic acid biosynthesis in glioma stem cells

scientific article published on 21 December 2021

Biochemical characterization of human epidermal retinol dehydrogenase 2

scientific article

Characterization of Essential Domains in HSD17B13 for Cellular Localization and Enzymatic Activity

scientific article published on 24 September 2020

Characterization of human short chain dehydrogenase/reductase SDR16C family members related to retinol dehydrogenase 10.

scientific article published on 25 October 2016

Characterization of truncated mutants of human microsomal short-chain dehydrogenase/reductase RoDH-4.

scientific article published on February 2003

Chemico-Biological Interactions. Enzymology and molecular biology of carbonyl metabolism 16. Introduction

scientific article published in February 2013

Coelimination and Survival in Gene Network Evolution: Dismantling the RA-Signaling in a Chordate.

scientific article published on 12 July 2016

Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids

scientific article

Comparative genomic and phylogenetic analysis of short-chain dehydrogenases/reductases with dual retinol/sterol substrate specificity

scientific article published on 24 July 2006

Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers

scientific article published on 02 September 2015

Coordinated expression of valine catabolic enzymes during adipogenesis: analysis of activity, mRNA, protein levels, and metabolic consequences

scientific article published on December 1994

Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo

scientific article

Dietary Control and Tissue Specific Expression of Branched-Chain α-Ketoacid Dehydrogenase Kinase

scientific article published on 01 January 1995

Differential recognition of the free versus bound retinol by human microsomal retinol/sterol dehydrogenases: characterization of the holo-CRBP dehydrogenase activity of RoDH-4.

scientific article

Disease-associated variants of microsomal retinol dehydrogenase 12 (RDH12) are degraded at mutant-specific rates

scientific article

Diversity of the pyruvate dehydrogenase kinase gene family in humans

scientific article

Effect of cellular retinol-binding protein on retinol oxidation by human class IV retinol/alcohol dehydrogenase and inhibition by ethanol

scientific article

Effect of dietary protein on the liver content and subunit composition of the branched-chain alpha-ketoacid dehydrogenase complex

scientific journal article

Effect of lipid peroxidation products on the activity of human retinol dehydrogenase 12 (RDH12) and retinoid metabolism

scientific article published on 18 March 2008

Enzymology of retinoic acid biosynthesis and degradation

scientific article published on 29 April 2013

Evidence that proteosome inhibitors and chemical chaperones can rescue the activity of retinol dehydrogenase 12 mutant T49M.

scientific article

Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1).

scientific article

Evolutionary origins of retinoid active short-chain dehydrogenases/reductases of SDR16C family

scientific article published on November 2014

Human pancreas protein 2 (PAN2) has a retinal reductase activity and is ubiquitously expressed in human tissues

scientific article (publication date: 20 November 2002)

Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity

scientific article

Identification and characterization of retinoid-active short-chain dehydrogenases/reductases in Drosophila melanogaster

scientific article published on 09 June 2009

Introduction

scientific article published on 22 March 2011

Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase

scientific article

Lipoprotein particles of intraocular origin in human Bruch membrane: an unusual lipid profile

scientific article published on 20 September 2008

Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1.

scientific article

Mice lacking the epidermal retinol dehydrogenases SDR16C5 and SDR16C6 display accelerated hair growth and enlarged meibomian glands

scientific article published on 27 September 2019

Overproduction of bioactive retinoic acid in cells expressing disease-associated mutants of retinol dehydrogenase 12.

scientific article published on 9 October 2007

Properties of short-chain dehydrogenase/reductase RalR1: characterization of purified enzyme, its orientation in the microsomal membrane, and distribution in human tissues and cell lines.

scientific article

Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin

scientific article

Retinoic Acid Synthesis and Degradation

scientific article published on January 2016

Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

scientific article

Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture

scientific article

Role of microsomal retinol/sterol dehydrogenase-like short-chain dehydrogenases/reductases in the oxidation and epimerization of 3alpha-hydroxysteroids in human tissues

scientific article

Sdr16c5 and Sdr16c6 control a dormant pathway at a bifurcation point between meibogenesis and sebogenesis

scientific article published in 2023

Short chain dehydrogenase/reductase rdhe2 is a novel retinol dehydrogenase essential for frog embryonic development.

scientific article published on 30 January 2012

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative

scientific article

The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis

scientific article published on 22 February 2017

The effect of ligand binding on the proteolytic pattern of methylmalonate semialdehyde dehydrogenase.

scientific article

The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis

scientific article

cDNA cloning and characterization of a new human microsomal NAD+-dependent dehydrogenase that oxidizes all-trans-retinol and 3alpha-hydroxysteroids

scientific article