Search filters

List of works by Satoru Koyanagi

24-hour oscillation of mouse methionine aminopeptidase2, a regulator of tumor progression, is regulated by clock gene proteins

scientific article published in November 2004

24-hour rhythm of aquaporin-3 function in the epidermis is regulated by molecular clocks.

scientific article published on 13 January 2014

A disruption mechanism of the molecular clock in a MPTP mouse model of Parkinson's disease.

scientific article

A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells.

scientific article published in November 2003

Accumulation of sorbitol in the sciatic nerve modulates circadian properties of diabetes-induced neuropathic pain hypersensitivity in a diabetic mouse model

scientific article published on 08 June 2018

Alteration of circadian machinery in monocytes underlies chronic kidney disease-associated cardiac inflammation and fibrosis

scientific article published on 13 May 2021

Alteration of intrinsic biological rhythms during interferon treatment and its possible mechanism

scientific article published in December 2002

Alterations of Hepatic Metabolism in Chronic Kidney Disease via D-box-binding Protein Aggravate the Renal Dysfunction

scientific article published on 4 January 2016

An attempt to promote neo-vascularization by employing a newly synthesized inhibitor of protein tyrosine phosphatase

scientific article

Anti-apoptotic roles of plasminogen activator inhibitor-1 as a neurotrophic factor in the central nervous system.

scientific article published in December 2008

Application of Hamiltonian of ray motion to room acoustics

scientific article published on 01 August 2008

Aryl hydrocarbon receptor-mediated Cyp1a1 expression is modulated in a CLOCK-dependent circadian manner

scientific article published on 29 September 2011

Asthma: Chronopharmacotherapy and the molecular clock

scientific article published on 30 March 2010

Basic-helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates vascular endothelial growth factor expression

scientific article published on February 2008

Basis for dosing time-dependent change in the anti-tumor effect of imatinib in mice

scientific article published on 14 September 2006

Basis for dosing time-dependent changes in the antiviral activity of interferon-alpha in mice

scientific article published on 01 August 2000

Bezafibrate induces plasminogen activator inhibitor-1 gene expression in a CLOCK-dependent circadian manner.

scientific article published on 16 April 2010

Bile acid-regulated peroxisome proliferator-activated receptor-α (PPARα) activity underlies circadian expression of intestinal peptide absorption transporter PepT1/Slc15a1.

scientific article published on 11 July 2014

Cell-cycle-dependent pharmacology of methotrexate in HL-60.

scientific article published on 3 December 2005

Changing the dosing schedule minimizes the disruptive effects of interferon on clock function

scientific article published in March 2001

Chronic treatment with prednisolone represses the circadian oscillation of clock gene expression in mouse peripheral tissues

scientific article published on 3 November 2005

Chrono-drug delivery system based on the circadian rhythm of transferrin receptor

scientific article published in December 2013

Chronopharmacological study of antidepressants in forced swimming test of mice

scientific article published on 3 August 2005

Chronopharmacological study of interferon-alpha in mice.

scientific article published on October 1997

Chronopharmacology.

scientific article published on March 2011

Circadian Clock in a Mouse Colon Tumor Regulates Intracellular Iron Levels to Promote Tumor Progression

scientific article published on 21 January 2016

Circadian changes of D-alanine and related compounds in rats and the effect of restricted feeding on their amounts

scientific article published in November 2008

Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function.

scientific article published on 13 June 2018

Circadian clock-controlled intestinal expression of the multidrug-resistance gene mdr1a in mice

scientific article

Circadian mRNA expression of coagulation and fibrinolytic factors is organ-dependently disrupted in aged mice

scientific article published on 21 September 2011

Circadian modulation in the intestinal absorption of P-glycoprotein substrates in monkeys

scientific article published on 21 April 2015

Circadian regulation of mTOR by the ubiquitin pathway in renal cell carcinoma

scientific article published on 19 November 2013

Circadian regulation of mouse topoisomerase I gene expression by glucocorticoid hormones

scientific article published on 14 February 2006

Circadian rhythm of transferrin receptor 1 gene expression controlled by c-Myc in colon cancer-bearing mice

scientific article published on 14 July 2010

Clock gene dysfunction in patients with obstructive sleep apnoea syndrome

scientific article published on 5 March 2008

Clock gene mutation modulates the cellular sensitivity to genotoxic stress through altering the expression of N-methylpurine DNA glycosylase gene.

scientific article published on 18 June 2009

Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder

scientific article

Dosing time-dependent changes in the analgesic effect of pregabalin on diabetic neuropathy in mice

scientific article published on 11 May 2015

Dysfunction of the circadian transcriptional factor CLOCK in mice resists chemical carcinogen-induced tumorigenesis

scientific article published on 30 August 2017

Effect of dosing schedule on pharmacokinetics of alpha interferon and anti-alpha interferon neutralizing antibody in mice.

scientific article published on January 2001

Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase

scientific article published in May 2003

Estradiol regulation of P-glycoprotein expression in mouse kidney and human tubular epithelial cells, implication for renal clearance of drugs

scientific article published on 17 September 2019

Glucocorticoid hormone regulates the circadian coordination of micro-opioid receptor expression in mouse brainstem

scientific article published on 18 August 2005

Glucocorticoid is involved in food-entrainable rhythm of mu-opioid receptor expression in mouse brainstem and analgesic effect of morphine

scientific article published on 9 May 2006

Glucocorticoid regulation of 24-hour oscillation in interferon receptor gene expression in mouse liver

scientific article published on 17 August 2006

Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia

scientific article published on 14 October 2016

Glucocorticoid-dependent expression of O(6)-methylguanine-DNA methyltransferase gene modulates dacarbazine-induced hepatotoxicity in mice

scientific article published on 22 March 2010

Hypoxia-response plasmid vector producing bcl-2 shRNA enhances the apoptotic cell death of mouse rectum carcinoma

scientific article published on 16 July 2010

Induction of cardiac fibrosis by β-blocker in G protein-independent and G protein-coupled receptor kinase 5/β-arrestin2-dependent Signaling pathways.

scientific article

Influence of CLOCK on cytotoxicity induced by diethylnitrosamine in mouse primary hepatocytes

scientific article published on 15 December 2010

Influence of intermittent hypoxia on the signal transduction pathways to inflammatory response and circadian clock regulation.

scientific article

Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease

scientific article (publication date: November 2016)

Intestinal Expression of Mouse Abcg2/Breast Cancer Resistance Protein (BCRP) Gene Is under Control of Circadian Clock-activating Transcription Factor-4 Pathway ⬇️

scientific article published on March 6, 2012

JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

scientific article

Large-scale production of major house dust mite allergen der f 2 mutant (C8/119S) in Escherichia coli.

scientific article

Methotrexate chronotherapy is effective against rheumatoid arthritis.

scientific article published on April 2011

Mitomycin C modulates the circadian oscillation of clock gene period 2 expression through attenuating the glucocorticoid signaling in mouse fibroblasts

scientific article published on 21 September 2015

Modulation of circadian rhythm of DNA synthesis in tumor cells by inhibiting platelet-derived growth factor signaling

scientific article

Modulation of peroxisome proliferator-activated receptor-α activity by bile acids causes circadian changes in the intestinal expression of Octn1/Slc22a4 in mice

scientific article published on 24 November 2014

Modulatory effects of 5-fluorouracil on the rhythmic expression of circadian clock genes: a possible mechanism of chemotherapy-induced circadian rhythm disturbances

scientific article published on 5 February 2008

Molecular Basis of Chronopharmaceutics ⬇️

scientific article published on 07 June 2011

Molecular basis for rhythmic expression of CYP3A4 in serum-shocked HepG2 cells

scientific article published on December 2007

Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain

scientific article published on 26 November 2010

Molecular basis of choronopharmacology

scientific article

Molecular mechanism regulating 24-hour rhythm of dopamine D3 receptor expression in mouse ventral striatum

scientific article published on 21 February 2013

Mutation of the gene encoding the circadian clock component PERIOD2 in oncogenic cells confers chemoresistance by up-regulating the Aldh3a1 gene

scientific article published on 14 November 2018

Nociceptin system does not affect MAC of volatile anaesthetics.

scientific article published in July 2005

Obesity, body fat distribution and coronary atherosclerosis among Japanese men and women

scientific article published on 01 February 2001

Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities

scientific article published on 01 January 2003

Periodic variation in bile acids controls circadian changes in uric acid via regulation of xanthine oxidase by the orphan nuclear receptor PPARα.

scientific article published on 3 November 2017

Plasminogen activator inhibitor-1 aids nerve growth factor-induced differentiation and survival of pheochromocytoma cells by activating both the extracellular signal-regulated kinase and c-Jun pathways

scientific article published on 04 May 2006

Plasminogen activator inhibitor-1 aids survival of neurites on neurons derived from pheochromocytoma (PC-12) cells

scientific article published in April 2004

Proxisome proliferator-activated receptor-α mediates high-fat, diet-enhanced daily oscillation of plasminogen activator inhibitor-1 activity in mice

scientific article published on October 2010

RNA editing enzyme ADAR1 governs the circadian expression of P-glycoprotein in human renal cells by regulating alternative splicing of the ABCB1 gene

scientific article published on 01 January 2021

Relationship between 24-hour rhythm in antiviral effect of interferon-beta and interferon-alpha/beta receptor expression in mice

scientific article published on December 2002

Relationship between diurnal rhythm of cell cycle and interferon receptor expression in implanted-tumor cells

scientific article published on 01 February 2001

Renal circadian clock regulates the dosing-time dependency of cisplatin-induced nephrotoxicity in mice

scientific article published on 24 February 2014

Rhythmic Control of the ARF-MDM2 Pathway by ATF4 Underlies Circadian Accumulation of p53 in Malignant Cells ⬇️

scientific article published on April 11, 2013

Role of activating transcription factor-4 in 24-hour rhythm of serotonin transporter expression in the mouse midbrain

scientific article published on 9 May 2012

Role of glucocorticoid receptor in the regulation of cellular sensitivity to irinotecan hydrochloride

scientific article published in February 2009

Role of prehypertension in the development of coronary atherosclerosis in Japan

scientific article published on 01 March 2004

Sequential immunization with V3 peptides from primary human immunodeficiency virus type 1 produces cross-neutralizing antibodies against primary isolates with a matching narrow-neutralization sequence motif.

scientific article

Simple and rapid genotyping of D-amino acid oxidase gene recognizing a crucial variant in the ddY strain using microchip electrophoresis

scientific article published in February 2009

Stress-regulated transcription factor ATF4 promotes neoplastic transformation by suppressing expression of the INK4a/ARF cell senescence factors

scientific article published on 18 November 2011

Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors

scientific article published on 2 November 2005

Synthesis and evaluation of multisubstrate analogue inhibitors of purine nucleoside phosphorylases.

scientific article

The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S

scientific article published on 25 September 2013

The long-term immunosuppressive effects of disulfide-linked HLA-G dimer in mice with collagen-induced arthritis

scientific article published on 29 December 2012

The molecular clock regulates circadian transcription of tissue factor gene

scientific article published on 04 January 2013

The molecular mechanism regulating 24-hour rhythm of CYP2E1 expression in the mouse liver

scientific article

Time-dependent interaction between differentiated embryo chondrocyte-2 and CCAAT/enhancer-binding protein α underlies the circadian expression of CYP2D6 in serum-shocked HepG2 cells

scientific article published on 21 February 2012

Two-dimensional high-performance liquid chromatographic determination of day-night variation of D-alanine in mammals and factors controlling the circadian changes

scientific article published on 4 June 2013

[A 21-year-old woman complaining of exertional shortness of breath]

scientific article published on 01 November 2004

[Echocardiographic findings in patients with acute coronary syndrome]

scientific article published on 01 February 2004

[Silent coronary spasm]

scientific article published on 01 September 2007

cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene

scientific journal article

Paulina is supported by:

About Paulina

Help