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List of works by Peter Buchwald

A general bilinear model to describe growth or decline time profiles

scientific article published on 25 August 2006

A local glucose-and oxygen concentration-based insulin secretion model for pancreatic islets

scientific article

A simple, predictive, structure-based skin permeability model.

scientific article

A three-parameter two-state model of receptor function that incorporates affinity, efficacy, and signal amplification

scientific article

Activity-limiting role of molecular size: size-dependency of maximum activity for P450 inhibition as revealed by qHTS data.

scientific article

An Open-Label, Single-Dose, Crossover Study of the Pharmacokinetics and Metabolism of Two Oral Formulations of 1-Octanol in Patients with Essential Tremor ⬇️

scientific article published on October 1, 2011

Attempts of ranking in a series of synthetic nonpsychotropic cannabinoids

scientific article published in January 2001

Barriers to remember: brain-targeting chemical delivery systems and Alzheimer's disease.

scientific article

Bilinear Model for the Size-Dependency of the CYP3A4 Inhibitory Activity of Structurally Diverse Compounds

scientific article published on 16 December 2013

Biphasic decline of β-cell function with age in euglycemic nonobese diabetic mice parallels diabetes onset

scientific article

Brain-Targeted Delivery of Estradiol

Brain-Targeting Chemical Delivery Systems and Their Cyclodextrin-Based Formulations in Light of the Contributions of Marcus E. Brewster.

scientific article published on 18 May 2016

CD40-targeting KGYY15 peptides do not efficiently block the CD40-CD40L interaction

scientific article published on 09 September 2019

Cell length growth in fission yeast: an analysis of its bilinear character and the nature of its rate change transition

scientific article

Cell length growth patterns in fission yeast reveal a novel size control mechanism operating in late G2 phase

scientific article published on 11 April 2016

Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

scientific article published on 17 June 2015

Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients

scientific article published on 29 June 2010

Comprehensive Metabolomics Study To Assess Longitudinal Biochemical Changes and Potential Early Biomarkers in Nonobese Diabetic Mice That Progress to Diabetes

scientific article

Computer-aided retrometabolic drug design: soft drugs ⬇️

scientific article published on July 1, 2007

Computer-assisted design of new drugs based on retrometabolic concepts.

scientific article

Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation

scientific article published on 10 July 2015

Corticosteroid design for the treatment of asthma: structural insights and the therapeutic potential of soft corticosteroids

scientific article published on January 2006

Design, Synthesis, and Evaluation of Novel Immunomodulatory Small Molecules Targeting the CD40⁻CD154 Costimulatory Protein-Protein Interaction

scientific article published on 11 May 2018

Designing safer (soft) drugs by avoiding the formation of toxic and oxidative metabolites.

scientific article published on February 2004

Differences in the glucocorticoid to progesterone receptor selectivity of inhaled glucocorticoids.

scientific article published on March 2006

Drug targeting by retrometabolic design: soft drugs and chemical delivery systems ⬇️

scientific article published on May 1, 2001

Drug targeting via retrometabolic approaches

scientific article published on October 1997

Effective and specific inhibition of the CD40-CD154 costimulatory interaction by a naphthalenesulphonic acid derivative

scientific article published on 15 July 2010

Effects of representative glucocorticoids on TNFα- and CD40L-induced NF-κB activation in sensor cells

scientific article

Experimental evaluation and computational modeling of the effects of encapsulation on the time-profile of glucose-stimulated insulin release of pancreatic islets

scientific article

FEM-based oxygen consumption and cell viability models for avascular pancreatic islets.

scientific article

Feasibility of Localized Metabolomics in the Study of Pancreatic Islets and Diabetes

scientific article published on 29 September 2019

Glucocorticoid receptor binding: a biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

scientific article published on 11 October 2007

Glucose-stimulated insulin release: Parallel perifusion studies of free and hydrogel encapsulated human pancreatic islets.

scientific article published on 2 September 2017

High-throughput screening for human galactokinase inhibitors

scientific article

In vitro and in vivo evaluations of dihydroquinoline- and dihydroisoquinoline-based targetor moieties for brain-specific chemical delivery systems

scientific article

Influence of the N-acetylation polymorphism on the metabolism of talampanel: an investigation in fasted and fed subjects genotyped for NAT2 variants.

scientific article published in February 2006

Is there a universal rule for cellular growth?--Problems in studying and interpreting this phenomenon

scientific article

Local delivery of fingolimod from three-dimensional scaffolds impacts islet graft efficacy and microenvironment in a murine diabetic model

scientific article

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

scientific article published on 28 April 2017

Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.

scientific article published on June 2010

Novel, cell-penetrating molecular transporters with flexible backbones and permanently charged side-chains

scientific article published on 01 August 2007

Octanol-water partition of nonzwitterionic peptides: predictive power of a molecular size-based model

scientific article published in January 1998

Ophthalmic drug design based on the metabolic activity of the eye: soft drugs and chemical delivery systems.

scientific article

Organic dyes as small molecule protein-protein interaction inhibitors for the CD40-CD154 costimulatory interaction.

scientific article published in January 2010

Oscillatory dynamics of Cdc42 GTPase in the control of polarized growth. ⬇️

scientific article

Pharmacokinetic and pharmacodynamic evaluations of the zwitterionic metabolite of a new series of N-substituted soft anticholinergics

scientific article published on 26 September 2005

Pharmacokinetics and delta1-cortienic acid excretion after intravenous administration of prednisolone and loteprednol etabonate in rats.

scientific article published on June 2010

Pharmacokinetics of the sequential metabolites of loteprednol etabonate in rats

scientific article

Pharmacological effects of some newly developed soft anticholinergics and a receptor-binding QSAR study.

scientific article

Phosphorylation-dependent inhibition of Cdc42 GEF Gef1 by 14-3-3 protein Rad24 spatially regulates Cdc42 GTPase activity and oscillatory dynamics during cell morphogenesis

scientific article

Quantification of the islet product: presentation of a standardized current good manufacturing practices compliant system with minimal variability

scientific article

Quantitative assessment of islet cell products: estimating the accuracy of the existing protocol and accounting for islet size distribution.

scientific article published on 9 October 2009

RNA aptamers specific for transmembrane p24 trafficking protein 6 and Clusterin for the targeted delivery of imaging reagents and RNA therapeutics to human β cells

scientific article published on 05 April 2022

Recent advances in retrometabolic drug design (RMDD) and development.

scientific article published on June 2010

Recent advances in the design and development of soft drugs

scientific article published on June 2014

Resealable, optically accessible, PDMS-free fluidic platform for ex vivo interrogation of pancreatic islets.

scientific article

Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction

scientific article

Small-molecule costimulatory blockade: organic dye inhibitors of the CD40-CD154 interaction

scientific article published on 26 August 2009

Small-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction

scientific article

Small-molecule protein-protein interaction inhibitors: therapeutic potential in light of molecular size, chemical space, and ligand binding efficiency considerations.

scientific article

Soft corticosteroids for local immunosuppression: exploring the possibility for the use of loteprednol etabonate for islet transplantation

scientific article published in March 2008

Soft drugs: design principles, success stories, and future perspectives

scientific article published on 01 June 2020

Soft quaternary anticholinergics: comprehensive quantitative structure-activity relationship (QSAR) with a linearized biexponential (LinBiExp) model

scientific article published in February 2006

Structural studies on the chiral selector capacity of cyclodextrin derivatives

scientific article published on 14 January 2008

Structure-metabolism relationships: steric effects and the enzymatic hydrolysis of carboxylic esters.

scientific article

Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects

scientific article published in April 2009

Synthesis and pharmacological effects of new, N-substituted soft anticholinergics based on glycopyrrolate.

scientific article

The Effect of Recovery Warm-up Time Following Cold Storage on the Dynamic Glucose-stimulated Insulin Secretion of Isolated Human Islets

scientific article published on 01 January 2020

The food colorant erythrosine is a promiscuous protein-protein interaction inhibitor

scientific article published on 8 January 2011

The promiscuous protein binding ability of erythrosine B studied by metachromasy (metachromasia).

scientific article published on April 2013

The quantitative characterization of free radical sources and traps by electromigration applications.

scientific article published on 7 January 2008

Unified pharmacogenetics-based parent-metabolite pharmacokinetic model incorporating acetylation polymorphism for talampanel in humans

scientific article published in August 2005

Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer

scientific article published on 27 April 2016

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