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List of works by Hirohisa Saito

'Working' cardiomyocytes exhibiting plateau action potentials from human placenta-derived extraembryonic mesodermal cells

scientific article published on 5 May 2007

A Comparison of Self-Rated and Female Partner-Rated Scales in the Assessment of Paternal Prenatal Depression

scientific article published on 26 August 2015

A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro

scientific article

A functional polymorphism in MMP-9 is associated with childhood atopic asthma

scientific article published on 01 May 2006

A novel in vitro method for detecting undifferentiated human pluripotent stem cells as impurities in cell therapy products using a highly efficient culture system

scientific article

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

scientific article

Activated Human Mast Cells Release Factors Supporting Eosinophil Survival in vitro

Activation of basophils and mast cells for mediator release

scientific article published on January 1987

Activation of human mast cells through the platelet-activating factor receptor

scientific article published on 14 April 2010

Acute basophilic leukemia lacking basophil-specific antigens: the importance of cytokine receptor expression in differential diagnosis

scientific article

Adherence of Eosinophils to Endothelial Cells Stimulated with Human Mast Cell Supernatants

Adrenocortical function in patients with severe atopic dermatitis

scientific article published on 01 July 2000

Adrenomedullin is highly expressed in blood monocytes associated with acute Kawasaki disease: a microarray gene expression study

scientific article published on 5 November 2004

Advances in mechanisms of allergic disease in 2016.

scientific article published on 13 October 2017

Allergen-specific IgG4 over time: Observation among adults with hydrolyzed wheat protein allergy

scientific article published on 28 May 2019

Allergic profiles of mothers and fathers in the Japan Environment and Children's Study (JECS): a nationwide birth cohort study.

scientific article published on 7 August 2017

Allergy and hypersensitivity—airway inflammation and remodeling

scientific article published on 23 October 2007

Allergy: from history to today

scientific article published in March 2013

Amphiregulin is not essential for induction of contact hypersensitivity

scientific article published on 25 June 2010

Amphiregulin production by human eosinophils

scientific article published on 3 June 2009

An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.

scientific article

An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway

scientific article published on 24 January 2006

Analysis of gene expression in peripheral blood eosinophils from patients with atopic dermatitis and in vitro cytokine-stimulated blood eosinophils

article

Analysis of gene expression in peripheral blood eosinophils from patients with atopic dermatitis by differential display.

scientific article published in June 2003

Analysis of gene expressions of T cells from children with acute exacerbations of asthma.

scientific article published on 25 March 2004

Analysis of highly expressed genes in monocytes from atopic dermatitis patients.

scientific article published on October 2003

Analysis of signal transduction pathways involved in anti-CD30 mAb-induced human eosinophil apoptosis.

scientific article published on 4 June 2010

Anti-inflammatory effects of high-dose IgG on TNF-α-activated human coronary artery endothelial cells.

scientific article

Antigen-specific T-cell responses in patients with non–IgE-mediated gastrointestinal food allergy are predominantly skewed to TH2

article

Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells

scientific article

Antimicrobial peptides human β-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability

scholarly article by Xuejun Chen et al published February 2007 in European Journal of Immunology

Application of moisturizer to neonates prevents development of atopic dermatitis

article

Application to Allergic Diseases

scientific article published on 01 April 2005

Are both early egg introduction and eczema treatment necessary for primary prevention of egg allergy?

scholarly article by Kenji Matsumoto et al published June 2018 in The Journal of Allergy and Clinical Immunology

Association between genetic variation in the gene for death-associated protein-3 (DAP3) and adult asthma

scientific article

Carnoy's fixative reduces the number of chymase-positive cells in immunocytochemical staining of cord-blood-derived human cultured mast cells

scientific article published on 01 October 1998

Caspase-1, Caspase-8, and Calpain Are Dispensable for IL-33 Release by Macrophages

scientific article published on 01 December 2009

Catestatin, a neuroendocrine antimicrobial peptide, induces human mast cell migration, degranulation and production of cytokines and chemokines

scientific article

Celebration of the 50th anniversary of IgE discovery

scientific article published on 20 September 2016

Cell type-dependent effects of corticosteroid on periostin production by primary human tissue cells

article

Changes in Filament Actin Accompanying IgE-Dependent and -Independent Histamine Release from IL3-Dependent Cultured Human Basophils

scientific article published on 01 January 1991

Characteristics of histamine release from cultured human mast cells

scientific article published on 01 May 1996

Characterization of 'adult-type' mast cells derived from human bone marrow CD34(+) cells cultured in the presence of stem cell factor and interleukin-6. Interleukin-4 is not required for constitutive expression of CD54, Fc epsilon RI alpha and chyma

scientific article published in June 2002

Characterization of Cord-Blood-Derived Human Mast Cells Cultured in the Presence of Steel Factor and lnterleukin-6

scientific article published on 01 May 1995

Chemotactic responses of peripheral blood eosinophils to prostaglandin D2 in atopic keratoconjunctivitis

scientific article published on 28 June 2013

Childhood asthma control in Japan: A nationwide, cross-sectional, web-based survey

scientific article published on 01 March 2018

Chitin promotes antigen-specific Th2 cell-mediated murine asthma through induction of IL-33-mediated IL-1β production by DCs

scientific article published in Scientific Reports

Cholesteatoma Fibroblasts Promote Epithelial Cell Proliferation through Overexpression of Epiregulin ⬇️

scientific article published on June 24, 2013

Cimetidine Enhances Antigen-Specific IgE and Th2 Cytokine Production

article

Circulating Foxp3+CD4+ cell numbers in atopic patients and healthy control subjects

scientific article published on 12 July 2007

Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients

scientific article (publication date: 11 October 2002)

Combination of hTERT and bmi-1, E6, or E7 induces prolongation of the life span of bone marrow stromal cells from an elderly donor without affecting their neurogenic potential.

scientific article

Comparison of human tonsillar mast cell localization and ultrastructural observations between IgE-mediated allergic and nonallergic donors

scientific article published on 01 September 2006

Complications and adverse outcomes in pregnancy and childbirth among women who conceived by assisted reproductive technologies: a nationwide birth cohort study of Japan environment and children's study

scientific article published on 20 February 2019

Comprehensive examination of gene expression associated with long-term stable graft acceptance by renal transplant recipients.

scientific article

Consensus Communication on Early Peanut Introduction and Prevention of Peanut Allergy in High-Risk Infants

scientific article published on 10 September 2015

Consensus Communication on Early Peanut Introduction and the Prevention of Peanut Allergy in High-risk Infants

scientific article published on 31 August 2015

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

article

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

article published in 2015

Consensus communication on early peanut introduction and the prevention of peanut allergy in high-risk infants

Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells

scientific article

Continuous Isoproterenol Inhalation Therapy in Children with Severe Asthmatic Attack

scientific article published on 01 May 1997

Contributions of Interleukin-33 and TSLP in a papain-soaked contact lens-induced mouse conjunctival inflammation model.

scientific article published on 20 July 2017

Controlling the peripheral clock might be a new treatment strategy in allergy and immunology

scientific article published on 9 November 2015

Corneal and Conjunctival Fibroblasts Are Major Sources of Eosinophil-Recruiting Chemokines

scientific article published on 25 August 2009

Corticosteroid and cytokines synergistically enhance toll-like receptor 2 expression in respiratory epithelial cells

scientific article published on 8 July 2004

Corticosteroid enhances TNF-alpha-mediated leukocyte adhesion to pulmonary microvascular endothelial cells

scientific article

CpG Oligodeoxynucleotide Prolongs Eosinophil Survival through Activation of Contaminating B Cells and Plasmacytoid Dendritic Cells in vitro

scientific article published on 09 June 2006

CpG oligodeoxynucleotides directly induce CXCR3 chemokines in human B cells.

scientific article published on August 2004

Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.

scientific article published on 17 March 2014

Culture of human mast cells from peripheral blood progenitors

article

Cultured basophils but not cultured mast cells induce human IgE synthesis in B cells after immunologic stimulation

Cytokine requirement for the development of rat dendritic cells by in vitro culturing of bone marrow cells

article

Defining cell identity by comprehensive gene expression profiling.

scientific article published on January 2010

Detection of Diagnostic Markers for Allergic Inflammatory Diseases by a Microarray Method

scientific article published on 01 June 2007

Determination of a novel haplotype of beta2-adrenergic receptor in the Japanese population by the combination of the electronic microchip assay using the NanoChip system with allele-specific PCR.

scientific article published in January 2002

Development of IL-17-mediated Delayed-Type Hypersensitivity Is Not Affected by Down-Regulation of IL-25 Expression

article

Development of Tryptase-Positive KU812 Cells Cultured in the Presence of Steel Factor

scientific article published on 01 May 1995

Development of chronic allergic responses by dampening Bcl6-mediated suppressor activity in memory T helper 2 cells

scientific article published on 17 January 2017

Development of human mast cells in vitro

scientific article

Dexamethasone and FK506 inhibit expression of distinct subsets of chemokines in human mast cells

scientific article

Differences in lymphocyte gene expression between tolerant and syngeneic liver grafted rats

scientific article published in March 2004

Differential gene expression profile between cord blood progenitor-derived and adult progenitor-derived human mast cells

scientific article published on 4 January 2005

Differential type I IFN-inducing abilities of wild-type versus vaccine strains of measles virus

scientific article published on November 2007

Distinct Gene Expression Profiles Characterize Cellular Phenotypes of Follicle-Associated Epithelium and M Cells

article

Distinct gene expression profiles and regulation networks of nasal polyps in eosinophilic and non-eosinophilic chronic rhinosinusitis

scientific article published on 16 January 2018

Distinct response in maintenance of human naive and memory B cells via IL-21 receptor and TCL1/Akt pathways

scientific article published on 23 February 2009

Distribution and role of mast cells in human tonsil

Earlier aggressive treatment to shorten the duration of eczema in infants resulted in fewer food allergies at 2 years of age

scientific article published on 09 December 2019

Eczematous sensitization, a novel pathway for allergic sensitization, can occur in an early stage of eczema

scientific article published on 01 October 2014

Effect of Chinese herbal medicines and disodium cromoglycate on IgE-dependent histamine release from mouse cultured mast cells

scientific article published on November 1997

Effect of Th1/Th2 cytokine pretreatment on RSV-induced gene expression in airway epithelial cells.

scientific article published on 21 September 2010

Effect of a Chymotrypsin-like Inhibitor, TPCK, on Histamine Release from Cultured Human Mast Cells

scientific article published on 01 May 1997

Effect of cholera toxin on histamine release from bone marrow-derived mouse mast cells

scientific article

Effect of extracellular matrix proteins on platelet-activating factor-induced eosinophil chemotaxis

scientific article

Effect of filaggrin loss-of-function mutations on atopic dermatitis in young age: a longitudinal birth cohort study

scientific article published on 28 June 2019

Effect of heat treatment and enzymatic digestion on the B cell epitopes of cow's milk proteins

scientific article published on 10 March 2009

Effect of lidocaine on histamine release and Ca2+ mobilization from mast cells and basophils

scientific article

Effects of diesel exhaust particles on primary cultured healthy human conjunctival epithelium

scientific article

Egg antigen was more abundant than mite antigen in children's bedding: Findings of the pilot study of the Japan Environment and Children's Study (JECS)

scientific article published on 05 March 2019

Elevated granulocyte colony-stimulating factor levels predict treatment failure in patients with Kawasaki disease

scientific article published on 19 October 2008

Environmental factors associated with childhood eczema: Findings from a national web-based survey

scientific article

Enzyme replacement therapy in Japanese Fabry disease patients: the results of a phase 2 bridging study

scientific article

Eosinophil degranulation during pregnancy and after delivery by cesarean section

scientific article published in June 2003

Epicutaneous Allergic Sensitization by Cooperation between Allergen Protease Activity and Mechanical Skin Barrier Damage in Mice.

scientific article published on 14 March 2016

Epicutaneous immunity and onset of allergic diseases - per-"eczema"tous sensitization drives the allergy march

scientific article

Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma

scientific article published on 31 August 2012

Erratum: The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

article

Essentials for starting a pediatric clinical study (2): Role of environment and immunity in the development of childhood allergic and immunologic disorders.

scientific article published on January 2009

Evaluation of the staphylococcal exotoxins and their specific IgE in childhood atopic dermatitis☆☆☆

scientific article published on 01 August 1999

Expression of a human SOCS protein, HSOCP-1, in peripheral blood eosinophils from patients with atopic dermatitis

scientific article published on June 2004

Expression of thymus and activation-regulated chemokine (TARC) by human dermal cells, but not epidermal keratinocytes

scientific article published on 28 August 2014

Extremely rapid and intense induction of apoptosis in human eosinophils by anti-CD30 antibody treatment in vitro

scientific article published in February 2004

Factors associated with asthma control in children: findings from a national Web-based survey

scientific article published in December 2014

Factors associated with steroid phobia in caregivers of children with atopic dermatitis

scientific article published on 2 July 2012

Factors associated with the severity of childhood rhinoconjunctivitis

scientific article

Fc RI-mediated thymic stromal lymphopoietin production by interleukin-4-primed human mast cells

article

FcepsilonRI-mediated amphiregulin production by human mast cells increases mucin gene expression in epithelial cells

scientific article published in February 2005

Food protein-induced enterocolitis syndromes with and without bloody stool have distinct clinicopathologic features.

scientific article published on 16 June 2017

Four distinct subtypes of non–IgE-mediated gastrointestinal food allergies in neonates and infants, distinguished by their initial symptoms

scientific article published on 01 March 2011

Four phenotypes of atopic dermatitis in Japanese children: A general population birth cohort study

scientific article published on 30 March 2019

Functional Analysis of the Thymic Stromal Lymphopoietin Variants in Human Bronchial Epithelial Cells

article

Functional Polymorphism in theSuppressor of Cytokine Signaling 1Gene Associated with Adult Asthma

scientific article published in April 2007

Galectin-9 enhances cytokine secretion, but suppresses survival and degranulation, in human mast cell line

scientific article

Gene Expression Accompanied by Differentiation of Cord Blood-Derived CD34+ Cells to Eosinophils

article

Gene Expression Profiling of Human Mast Cell Subtypes: An In Silico Study

article

Gene Expression Profiling of the Effect of High-Dose Intravenous Ig in Patients with Kawasaki Disease

article

Gene expression profiles for Fc epsilon RI, cytokines and chemokines upon Fc epsilon RI activation in human cultured mast cells derived from peripheral blood

scientific article (publication date: 21 November 2001)

Gene expression profiles of human mast cells and basophils

article

Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.

scientific article

Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations

scientific journal article

Global DNA hypomethylation coupled to cellular transformation and metastatic ability.

scientific article published on 19 November 2015

Gremlin enhances the determined path to cardiomyogenesis

scientific article

Growth in Methylcellulose of Human Mast Cells in Hematopoietic Colonies Stimulated by Steel Factor, a c-ki t Ligand

scientific article published on 01 January 1994

HLA-DQ and RBFOX1 as susceptibility genes for an outbreak of hydrolyzed wheat allergy

scientific article published on 10 July 2019

Having small-for-gestational-age infants was associated with maternal allergic features in the JECS birth cohort

scientific article published on 19 June 2018

Hev B 6.02 is the most important allergen in health care workers sensitized occupationally by natural rubber latex gloves

scientific article

High-Density Oligonucleotide Array Analysis of mRNA Transcripts in Peripheral Blood Cells of Severe Atopic Dermatitis Patients

article

Human Mast Cell Colony-Forming Cells in Culture

Human eosinophils constitutively express a unique serine protease, PRSS33.

scientific article published on 16 February 2017

Human eosinophils produce and release a novel chemokine, CCL23, in vitro

scientific article published in June 2011

Human mast cell activation through Fc receptors and Toll-like receptors

Human mast cell progenitors in peripheral blood from atopic subjects with high IgE levels.

scientific article

Human mast cell transcriptome project.

scientific article published in May 2001

Human mast cells express receptors for IL-3, IL-5 and GM-CSF; a partial map of receptors on human mast cells cultured in vitro

scientific article published in October 2004

Human sclera maintains common characteristics with cartilage throughout evolution

scientific article

Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts

scientific article published on April 2007

Hyperexpression of FcγRI and Toll-like receptor 4 in the intestinal mast cells of Crohn’s disease patients

Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells

scientific article

Hypoproteinemia in severe childhood atopic dermatitis: a serious complication.

scientific article

IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model

article

IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice

scientific article published on 31 July 2015

IL-25 enhances TH17 cell-mediated contact dermatitis by promoting IL-1β production by dermal dendritic cells.

scientific article published on 6 March 2018

IL-25, IL-33 and TSLP receptor are not critical for development of experimental murine malaria.

scientific article published on 14 December 2015

IL-33 Receptor-Expressing Regulatory T Cells Are Highly Activated, Th2 Biased and Suppress CD4 T Cell Proliferation through IL-10 and TGFβ Release

scientific article

IL-33 and Airway Inflammation.

scientific article

IL-33 can promote survival, adhesion and cytokine production in human mast cells

article

IL-33 in clinical practice: Size matters?

scientific article published on 3 May 2017

IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals

scientific article published on 19 September 2007

IL-33 induces functional CCR7 expression in human mast cells

scientific article published on 19 June 2018

IL-33 is a crucial amplifier of innate rather than acquired immunity

scientific article

IL-33 mediates inflammatory responses in human lung tissue cells

scientific article

IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms

scientific article

IL-33, IL-25 and TSLP contribute to development of fungal-associated protease-induced innate-type airway inflammation

scientific article published in Scientific Reports

IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis.

scientific article

IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation.

scientific article

IQGAP1 and vimentin are key regulator genes in naturally occurring hepatotumorigenesis induced by oxidative stress

scientific article published on 16 December 2009

Identification of Highly Expressed Genes in Peripheral Blood T Cells from Patients with Atopic Dermatitis

article

Identification of Nash1, a novel protein containing a nuclear localization signal, a sterile alpha motif, and an SH3 domain preferentially expressed in mast cells

scientific article

Identification of granulocyte subtype-selective receptors and ion channels by using a high-density oligonucleotide probe array

scientific article published in March 2004

Identification of novel mast cell genes by serial analysis of gene expression in cord blood-derived mast cells

article

Identification of specific gene expression profiles in fibroblasts derived from middle ear cholesteatoma.

scientific article

Identification of specific gene expression profiles in human mast cells mediated by Toll-like receptor 4 and Fc RI

article

Identification of tryptase- and chymase-related gene clusters in human mast cells using microarrays

scientific article published in March 2006

IgE antibody concentration, specific activity, clonality, and affinity measures from future diagnostic confirmatory tests

article

IgE-class-specific immunosuppression in offspring by administration of anti-IgE to pregnant mice

scientific article published on 22 November 2018

Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients

scientific article published in May 2009

Impaired interferon-gamma production in a subset population of severe atopic dermatitis.

scientific article published in June 2004

In drug-induced, immune-mediated hepatitis, interleukin-33 reduces hepatitis and improves survival independently and as a consequence of FoxP3+ T-cell activity

scientific article published on 20 July 2018

Increased production of vascular endothelial growth factor-d and lymphangiogenesis in acute Kawasaki disease

scientific article

Induction of apoptosis in human basophils by anti-Fas antibody treatment in vitro

scientific article published on 27 May 2008

Induction of human IgE synthesis in B cells by a basophilic cell line, KU812.

scientific article published on May 1997

Infantile eczema at one month of age is associated with cord blood eosinophilia and subsequent development of atopic dermatitis and wheezing illness until two years of age.

scientific article published on 2 June 2005

Influence of antibiotic use in early childhood on asthma and allergic diseases at age 5.

scientific article

Innate Lymphoid Cells in the Airways: Their Functions and Regulators

scientific article published on 01 May 2020

Innate Lymphoid Cells in the Induction of Obesity

scientific article published on 01 July 2019

Interferon-gamma promotes the survival and FcepsilonRI-mediated histamine release in cultured human mast cells

scientific article published on 01 December 1996

Interleukin 4 induces CD4+/CD8− to CD8+/CD4− transformation of human neonatal T cells by way of a double positive intermediate

scientific article published on 01 April 1990

Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion

Interleukin-33 enhances adhesion, CD11b expression and survival in human eosinophils

scientific article

Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.

scientific article published on 21 January 2016

Interleukin-8 Concentrations in Conjunctival Epithelium Brush Cytology Samples Correlate With Neutrophil, Eosinophil Infiltration, and Corneal Damage

scientific article published on 01 October 2001

Intra-articular Injected synovial stem cells differentiate into meniscal cells directly and promote meniscal regeneration without mobilization to distant organs in rat massive meniscal defect.

scientific article

Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits.

scientific article

Involvement of eosinophils in the onset of asthma

scientific article published on 03 December 2007

Ion channel gene expression in human lung, skin, and cord blood-derived mast cells

scientific article published in May 2003

Lactobacillus rhamnosus GG and Lactobacillus casei suppress Escherichia coli-induced chemokine expression in intestinal epithelial cells

scientific article

Large scale genotyping study for asthma in the Japanese population

scientific article

Legends of Allergy & Immunology: KImishige Ishizaka

scientific article published on 23 August 2018

Localization of human interleukin 13 receptor in non-haematopoietic cells

scientific article

Marked increase in CC chemokine gene expression in both human and mouse mast cell transcriptomes following Fcepsilon receptor I cross-linking: an interspecies comparison

article

Mast Cell Research

Mast Cells

Mast cell-/basophil-specific transcriptional regulation of human L-histidine decarboxylase gene by CpG methylation in the promoter region

scientific article published on November 1998

Mast cell-mediated airway remodelling

Mast cells and IgE: from history to today

scientific article

Mast cells and T-cell expansion

Mast cells as sources of cytokines, chemokines, and growth factors.

scientific article published in March 2018

Measurement of allergen-specific secretory IgA in stool of neonates, infants and toddlers by protection against degradation of immunoglobulins and allergens

scientific article published in January 2015

Microarray analysis of gene expression in peripheral blood mononuclear cells derived from long-surviving renal recipients

article

Microarray-based identification of novel biomarkers in asthma

scientific article published on December 2006

Monitoring of inflammation in relation to pathophysiology

scientific article published on 01 January 1993

Much atopy about the skin: genome-wide molecular analysis of atopic eczema

scientific article

NR4A orphan nuclear receptor family in peripheral blood eosinophils from patients with atopic dermatitis and apoptotic eosinophils in vitro.

scientific article

Non-IgE-mediated gastrointestinal food allergies: distinct differences in clinical phenotype between Western countries and Japan.

scientific article published on August 2012

Novel Roles of Mast Cells in Modulating IgE-Mediated Allergic Inflammation

Nuclear expression of IL-33 in epidermal keratinocytes promotes wound healing in mice.

scientific article published on 17 October 2016

Omalizumab inhibits acceleration of FcεRI-mediated responsiveness of immature human mast cells by immunoglobulin E.

scientific article published in March 2012

Outbreak of immediate-type hydrolyzed wheat protein allergy due to a facial soap in Japan

scientific article published on 16 May 2017

Overexpression of LEDGF/DFS70 induces IL-6 via p38 activation in HaCaT cells, similar to that seen in the psoriatic condition.

scientific article published on 15 July 2010

Ovomucoid-specific IgG4 level in cord blood associates negatively with later sensitization

scientific article published on 01 October 2019

Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage activation

scientific journal article

Pathogenic role of a superantigen in Yersinia pseudotuberculosis infection

scientific article published on January 2003

Phenotypes of childhood wheeze in Japanese children: A group-based trajectory analysis

scientific article published on 05 June 2018

Platelet-Activating Factor-Induced Activation and Cytoskeletal Change in Cultured Eosinophils

scientific article published on 01 January 1990

Platelets constitutively express IL-33 protein and modulate eosinophilic airway inflammation.

scientific article published on 04 April 2016

Polyclonal IgE induces mast cell survival and cytokine production

scientific article

Preconceptional exposure to oral contraceptive pills and the risk of wheeze, asthma and rhinitis in children.

scientific article published on 30 March 2016

Presence of Eosinophils in Nasal Secretion during Acute Respiratory Tract Infection in Young Children Predicts Subsequent Wheezing within Two Months

scientific article published on 01 December 2008

Presence of eotaxin in tears of patients with atopic keratoconjunctivitis with severe corneal damage

scientific article published on 01 June 1999

Present state of Japanese cedar pollinosis: the national affliction

scientific article

Pretreatment with low levels of FcεRI-crosslinking stimulation enhances basophil mediator release

scientific article

Prevalence and impact of rhinitis in asthma. SACRA, a cross-sectional nation-wide study in Japan

scientific article published on 22 July 2011

Preventive effect of bedding encasement with microfine fibers on mite sensitization

scientific article published on 01 January 1998

Primary Immunodeficiency and Related Diseases

article

Proactive treatment appears to decrease serum immunoglobulin-E levels in patients with severe atopic dermatitis

scientific article published in November 2010

Problems to Be Resolved in the Management of Urticaria

scientific article published on 01 December 2012

Progress in allergy signal research on mast cells: systemic approach to mast cell biology in allergic diseases

scientific article published on March 2008

Prostaglandin A2 acts as a transactivator for NOR1 (NR4A3) within the nuclear receptor superfamily

scientific article

Prostaglandin D2 induces chemotaxis in eosinophils via its receptor CRTH2 and eosinophils may cause severe ocular inflammation in patients with allergic conjunctivitis

scientific article published on November 2005

Psychosocial factors and adherence to treatment advice in childhood atopic dermatitis

scientific article published in October 2001

RANTES production in a conjunctival epithelial cell line

scientific article published on September 1, 1997

Rapid and strong induction of apoptosis in human eosinophils by anti-CD30 mAb-coated microspheres and phagocytosis by macrophages

scientific article published in May 2007

Rationale and study design of the Japan environment and children's study (JECS)

scientific article (publication date: 10 January 2014)

Recent advances in understanding the roles of blood platelets in the pathogenesis of allergic inflammation and bronchial asthma

scientific article

Recent advances in understanding the roles of vascular endothelial cells in allergic inflammation

scientific article

Reciprocal regulation of cultured human mast cell cytokine production by IL-4 and IFN-γ

article

Regulation of IgE-dependent zinc release from human mast cells

scientific article published on 29 May 2013

Regulation of chymase production in human mast cell progenitors

article

Regulatory roles of mast cells in immune responses.

scientific article published on 6 May 2016

Relationship between Histamine Release and Leukotrienes Production from Human Basophils Derived from Atopic Dermatitis Donors

article

Relieving pain and distress during venipuncture: Pilot study of the Japan Environment and Children's Study (JECS)

scientific article published on 01 October 2015

Reply

scientific article published on 07 February 2015

Role of T cells and gamma interferon in Yersinia pseudotuberculosis-derived mitogen (YPM)-induced toxicity in mice

scientific article published on January 2003

Role of cyclic 3 ́,5 ́-adenosine monophosphate in the regulation of chemical mediator release and cytokine production from cultured human mast cells

article

Role of interleukin-33 in innate-type immune cells in allergy.

scientific article published on March 2013

Role of mast cell proteases in tissue remodeling

scientific article

Role of mast cells in airway remodeling of asthma

scientific article published on 01 August 2009

Roles of Epithelial Cell-Derived Type 2-Initiating Cytokines in Experimental Allergic Conjunctivitis.

scientific article

Roles of the transmembrane domain and the cytoplasmic domain of Fc epsilon RI alpha in immunoglobulin E-mediated up-regulation of surface Fc epsilon RI expression

scientific article published on March 2007

SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses

scientific article published on 29 June 2003

Salivary cortisol response to stress in young children with atopic dermatitis

scientific article published on 21 May 2012

Selective differentiation and proliferation of hematopoietic cells induced by recombinant human interleukins

scientific article

Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 levels

scientific article published on 02 March 2016

Shortening of human cell life span by induction of p16ink4a through the platelet-derived growth factor receptor beta.

scientific article

Silica and double-stranded RNA synergistically induce bronchial epithelial apoptosis and airway inflammation.

scientific article published on September 2014

State of the art: atopic dermatitis

scientific article published in June 2013

Stem Cell Factor Has a Suppressive Activity to IgE-Mediated Chemotaxis of Mast Cells

scientific article published on 01 March 2005

Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes

scientific article published on 21 March 2016

Suggestions for the Assessment of the Allergenic Potential of Genetically Modified Organisms

scientific article published on 08 June 2005

Superantigenic Yersinia pseudotuberculosis induces the expression of granzymes and perforin by CD4+ T cells

scientific article

Symptoms of Allergic Rhinitis in Women during Early Pregnancy Are Associated with Higher Prevalence of Allergic Rhinitis in Their Offspring

scholarly article by Miwa Shinohara et al published 2007 in Allergology International

T cell proliferation by direct cross-talk between OX40 ligand on human mast cells and OX40 on human T cells: comparison of gene expression profiles between human tonsillar and lung-cultured mast cells

scientific article

TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells

scientific article

TNF-alpha and IL-4 regulate expression of IL-13 receptor alpha2 on human fibroblasts

scientific article published on December 2003

TNF-alpha and IL-4 regulate expression of fractalkine (CX3CL1) as a membrane-anchored proadhesive protein and soluble chemotactic peptide on human fibroblasts

scientific article published in March 2004

TSLP receptor is not essential for house dust mite-induced allergic rhinitis in mice.

scientific article published on 6 June 2016

Targeting human mast cells expressing g-protein-coupled receptors in allergic diseases

scientific article published on September 2008

Th1/Th2 Cytokines Reciprocally RegulateIn VitroPulmonary Angiogenesis via CXC Chemokine Synthesis

scientific article published on 20 August 2007

Th17 and allergy.

scientific article published on June 2008

The Implications of the Upregulation of ICAM-1/VCAM-1 Expression of Corneal Fibroblasts on the Pathogenesis of Allergic Keratopathy

scientific article published on 01 December 2005

The Role of Eosinophils in Asthma: Sarastro or the Queen of the Night?

scientific article published on 01 August 2001

The effects of anti-asthma drugs on mediator release from cultured human mast cells

scientific article published on 01 October 1998

The establishment of a combined serum-free and serum-supplemented culture method of obtaining functional cord blood-derived human mast cells

article

The interaction between Lyn and FcεRIβ is indispensable for FcεRI-mediated human mast cell activation

The interleukin-33-p38 kinase axis confers memory T helper 2 cell pathogenicity in the airway.

scientific article published in February 2015

The optimal age for epicutaneous sensitization following tape-stripping in BALB/c mice.

scientific article published on 10 February 2018

The role of Staphylococcal enterotoxin in atopic keratoconjunctivitis and corneal ulceration

scientific article published on 10 April 2012

The stimuli releasing histamine from murine bone marrow-derived mast cells (BMMC). 3. Effect of coculture with 3T3 fibroblasts on the histamine releasability of BMMC

scientific article published on April 1, 1992

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

scientific article published on 19 January 2015

The unfolded protein response is activated in differentiating epidermal keratinocytes

scientific article published on 12 March 2009

Thrombospondin 1 Is an Autocrine Negative Regulator of Human Dendritic Cell Activation ⬇️

scientific article published on October 20, 2003

Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma

scientific article

Timing of eczema onset and risk of food allergy at 3 years of age: A hospital-based prospective birth cohort study.

scientific article

Tissue remodeling induced by hypersecreted epidermal growth factor and amphiregulin in the airway after an acute asthma attack

scientific article

Total serum IgE level influences oral food challenge tests for IgE-mediated food allergies

article

Trajectories of class-switching-related egg and cow's milk allergen-specific immunoglobulin isotype formation and its modification by eczema with low- and high-affinity immunoglobulin E during early infancy

scientific article published on 11 March 2019

Transepidermal water loss measurement during infancy can predict the subsequent development of atopic dermatitis regardless of filaggrin mutations

scientific article published on 29 October 2015

Transforming growth factor-beta(2) polymorphisms are associated with childhood atopic asthma.

scientific article

Two cases of pollen-food allergy syndrome to soy milk diagnosed by skin prick test, specific serum immunoglobulin E and microarray analysis

scientific article published in January 2009

Ultrastructure of eosinophils and basophils stimulated to develop in human cord blood mononuclear cell cultures containing recombinant human interleukin-5 or interleukin-3.

scientific article published in July 1989

Upregulation of the transcript level of GTPase activating protein KIAA0603 in T cells from patients with atopic dermatitis.

scientific article

Visual analog scale as a predictor of GINA-defined asthma control. The SACRA study in Japan

scientific article

Yogurt consumption in infancy is inversely associated with atopic dermatitis and food sensitization at 5 years of age: A hospital-based birth cohort study.

scientific article published on 6 January 2017

Zinc transporter Znt5/Slc30a5 is required for the mast cell-mediated delayed-type allergic reaction but not the immediate-type reaction

scientific article published on 18 May 2009

[ESTIMATED NUMBER OF PATIENTS WITH FOOD ALLERGY IN JAPAN: THE PRESENT STATUS AND ISSUES REGARDING EPIDEMIOLOGICAL INVESTIGATION]

scientific article published on 01 January 2018

[RESEARCHES NECESSARY TO BASIC LAW ON MEASURES AGAINST ALLERGIC DISEASES]

scientific article published on 01 January 2019

beta2-Adrenoceptor agonists enhance cytokine-induced release of thymic stromal lymphopoietin by lung tissue cells

scientific article published on 26 February 2010

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