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List of works by Jamel Mankouri

A comparative cell biological analysis reveals only limited functional homology between the NS5A proteins of hepatitis C virus and GB virus B.

scientific article

Bunyavirus requirement for endosomal K+ reveals new roles of cellular ion channels during infection ⬇️

scientific article published on 19 January 2018

Bunyaviruses are Dependent on K 2p Channels to Infect Cells

Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1.

scientific article published on 19 January 2011

Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness ⬇️

scientific article published on 06 September 2018

Early events in the generation of autophagosomes are required for the formation of membrane structures involved in hepatitis C virus genome replication ⬇️

scientific article published on 04 January 2016

Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase

scientific article

Expression of the NS3 protease of cytopathogenic bovine viral diarrhea virus results in the induction of apoptosis but does not block activation of the beta interferon promoter

scientific article published on 30 September 2009

Genetic mutations in the Kir6.2 subunit of KATP channels which cause CHI

doctoral thesis

Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle ⬇️

scientific article (publication date: 15 October 2016)

Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis ⬇️

scientific article

Hepatitis C virus NS5A protein blocks epidermal growth factor receptor degradation via a proline motif- dependent interaction ⬇️

scientific article published on 13 April 2015

Hepatitis C virus NS5A protein interacts with beta-catenin and stimulates its transcriptional activity in a phosphoinositide-3 kinase-dependent fashion

scientific article published on 21 October 2009

Ion Channels as Therapeutic Targets for Viral Infections: Further Discoveries and Future Perspectives

scientific article published on 03 August 2020

Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels

scientific article

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation ⬇️

scientific article published in November 2017

Modulation of Potassium Channels Inhibits Bunyavirus Infection ⬇️

scientific article published on 16 December 2015

Molecular cell biology of KATP channels: implications for neonatal diabetes

scientific article (publication date: August 2007)

Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection ⬇️

scientific article

Potassium is a trigger for conformational change in the fusion spike of an enveloped RNA virus. ⬇️

scientific article published on 20 April 2018

Release of Infectious Hepatitis C Virus from Huh7 Cells Occurs via a trans-Golgi Network-to-Endosome Pathway Independent of Very-Low-Density Lipoprotein Secretion ⬇️

scientific article published on 25 May 2016

Requirement for chloride channel function during the hepatitis C virus life cycle ⬇️

scientific article published on 21 January 2015

Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism

scientific article published on 8 April 2009

Serine phosphorylation of the hepatitis C virus NS5A protein controls the establishment of replication complexes ⬇️

scientific article

Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence

scientific article (publication date: 15 September 2009)

TMEM16A/ANO1 calcium-activated chloride channel as a novel target for the treatment of human respiratory syncytial virus infection

scientific article published on 27 October 2020

Targeting hepatitis C virus p7 channel activity reveals prospect for bimodal antiviral prophylaxis

The Subcellular Localisation of the Human Papillomavirus (HPV) 16 E7 Protein in Cervical Cancer Cells and Its Perturbation by RNA Aptamers. ⬇️

scientific article published on 26 June 2015

The cellular chloride channels CLIC1 and CLIC4 contribute to virus-mediated cell motility ⬇️

scientific article published on 8 February 2018

The hepatitis C virus non-structural protein NS5A alters the trafficking profile of the epidermal growth factor receptor

scientific article

Trafficking of ATP-sensitive potassium channels in health and disease

scientific article published on November 2007

Viral dependence on cellular ion channels - an emerging anti-viral target? ⬇️

scientific article published on 22 January 2017

Viruses and the fuel sensor: the emerging link between AMPK and virus replication

scientific article published on 28 April 2011

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