List of works by Mark W. Kieran

A POETIC Phase II study of continuous oral everolimus in recurrent, radiographically progressive pediatric low-grade glioma

scientific article published on 02 November 2020

A Phase I and Pharmacokinetic Study of Oral Dabrafenib in Children and Adolescent Patients with Recurrent or Refractory BRAF V600 Mutation-Positive Solid Tumors

scientific article published on 10 September 2019

A Phase II Study of Continuous Oral mTOR Inhibitor Everolimus for Recurrent, Radiographic-Progressive Neurofibromatosis Type 1-Associated Pediatric Low-Grade Glioma: A Neurofibromatosis Clinical Trials Consortium Study

scientific article published on 01 April 2020

A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.

scientific article published on 12 January 2017

A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer

scientific article

A five-gene hedgehog signature developed as a patient preselection tool for hedgehog inhibitor therapy in medulloblastoma.

scientific article published on 3 December 2014

A monoclonal antibody against chicken MHC class I (B-F) antigens

scientific article published on 01 January 1985

A multi-disciplinary consensus statement concerning surgical approaches to low-grade, high-grade astrocytomas and diffuse intrinsic pontine gliomas in childhood (CPN Paris 2011) using the Delphi method

scientific article published on 15 March 2013

A novel GIT2-BRAF fusion in pilocytic astrocytoma.

scientific article published on 15 November 2017

A novel method for rapid molecular subgrouping of medulloblastoma.

scientific article

A pediatric trial of radiation/cetuximab followed by irinotecan/cetuximab in newly diagnosed diffuse pontine gliomas and high-grade astrocytomas: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study.

scientific article

A phase I and biology study of gefitinib and radiation in children with newly diagnosed brain stem gliomas or supratentorial malignant gliomas

scientific article

A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors

scientific article

A phase I trial of etanidazole and hyperfractionated radiotherapy in children with diffuse brainstem glioma

scientific article published in April 2003

A phase II trial of a multi-agent oral antiangiogenic (metronomic) regimen in children with recurrent or progressive cancer.

scientific article

A phase-1 pharmacokinetic optimal dosing study of intraventricular topotecan for children with neoplastic meningitis: a Pediatric Brain Tumor Consortium study

scientific article published on 21 September 2012

A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase

scientific article published on 28 April 2006

A prospective phase II trial of vinblastine and methotrexate in multivessel intraluminal pulmonary vein stenosis in infants and children

scientific article published on 11 November 2011

A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome

scientific article

A prospective, blinded analysis of A-PROTEIN (recoverin or CAR protein) levels in pediatric patients with central nervous system tumors

scientific article published in September 2009

A small-molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo

scientific article

A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

scientific article published on 31 October 2003

AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma

scientific article published on September 2006

ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients

scientific article published on 24 January 2020

Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors.

scientific article published on 19 September 2012

Adjunct Targeted Biologic Inhibition Agents to Treat Aggressive Multivessel Intraluminal Pediatric Pulmonary Vein Stenosis.

scientific article published on 23 March 2018

Advances in pediatric neuro-oncology.

scientific article

An international study evaluating the epidemiology of intracranial germ cell tumors in the native versus immigrant Japanese populations: the need for an international registry

scientific article published in 2022

Angiogenesis inhibitors and hypoxia.

scientific article published in September 2003

Anti-angiogenic therapy in pediatric neuro-oncology.

scientific article

Anti-apoptosis mechanisms in malignant gliomas.

scientific article published on January 2008

Antiangiogenic (metronomic) chemotherapy for brain tumors: current and future perspectives.

scientific article published on July 2009

Antiangiogenic metronomic therapy for children with recurrent embryonal brain tumors

scientific article published on 6 December 2011

Aspirin-triggered proresolving mediators stimulate resolution in cancer

scientific article published on 12 March 2019

Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome.

scientific article

Association of rapidly progressive moyamoya syndrome with bevacizumab treatment for glioblastoma in a child with neurofibromatosis type 1.

scientific article

Automated Processing of Dynamic Contrast-Enhanced MRI: Correlation of Advanced Pharmacokinetic Metrics with Tumor Grade in Pediatric Brain Tumors.

scientific article

BET bromodomain inhibition of MYC-amplified medulloblastoma.

scientific article published on 2 December 2013

Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.

scientific article

Biological modification strategies following marrow ablative, high-dose chemotherapy (HDCT) with autologous hematopoietic stem cell rescue (AHSCR) for pediatric brain tumors.

scientific article published on April 2010

Biology of childhood osteogenic sarcoma and potential targets for therapeutic development: meeting summary.

scientific article published on November 2003

Biopsy for diffuse intrinsic pontine glioma: a reappraisal

scientific article published on 6 May 2016

Bone density in post-pubertal adolescent survivors of childhood brain tumors.

scientific article published on 29 August 2011

Brain tumors: from childhood through adolescence into adulthood

scientific article published on 10 May 2010

Brainstem lesions in neurofibromatosis type 1.

scientific article

CRAN-11. MULTIPLEXED IMMUNOFLUORESCENCE REVEALS POTENTIAL PD-1/PD-L1 PATHWAY VULNERABILITIES IN CRANIOPHARYNGIOMA

Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome.

scientific article published on 21 February 2018

Central Versus Extraventricular Neurocytoma in Children: A Clinicopathologic Comparison and Review of the Literature

scientific article

Challenges to curing primary brain tumours

scientific article published on 01 August 2019

Challenges with defining response to antitumor agents in pediatric neuro-oncology: A report from the response assessment in pediatric neuro-oncology (RAPNO) working group

article

Characteristics of children ≤36 months of age with DIPG: A report from the international DIPG registry

scientific article published in 2022

Chemotherapy for progressive low-grade gliomas in children older than ten years: the Dana-Farber experience

scientific article published in October 2003

Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin

scientific article published on 29 June 2018

Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome

scientific article published on July 2016

Clinical and treatment factors determining long-term outcomes for adult survivors of childhood low-grade glioma: A population-based study

scientific article published on 10 March 2016

Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors.

scientific article published on 19 January 2017

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

scientific article

Clinical, Pathological, and Molecular Characterization of Infant Medulloblastomas Treated with Sequential High-Dose Chemotherapy

scientific article published on 4 May 2016

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

scientific article

Clinicopathologic study of glioblastoma in children with neurofibromatosis type 1.

scientific article published on July 2010

Concomitant Use of Panobinostat and Reirradiation in Progressive DIPG: Report of 2 Cases

scientific article

Continuous remission of newly diagnosed and relapsed central nervous system atypical teratoid/rhabdoid tumor

scientific article (publication date: March 2005)

Contribution of bone microenvironment to leukemogenesis and leukemia progression

scientific article

Contributors

Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

Correction: Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples.

scientific article published in September 2010

Correlation of erythrocytic peripheral blood chimaerism and putative bone marrow precursors bearing erythroid differentiation (B-G) antigens using monoclonal antibodies immobilized on fluorescent latex spheres

scientific article published on 01 February 1984

Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma

scientific article published on 20 December 2011

Cutaneous reactions to targeted therapies in children with CNS tumors: A cross-sectional study

scientific article published on 28 February 2019

Cutaneovisceral angiomatosis with thrombocytopenia

scientific article

DIPG-02. TRANSLATIONAL MR IMAGING CORRELATES FOR MOLECULAR ANALYSES IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

scientific article published on 23 April 2019

DIPG-06. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES.

scientific article

DIPG-29. GENOMIC LANDSCAPE OF DIFFUSE INTRINSIC PONTINE GLIOMA: AN ANALYSIS OF THE DIPG-BATS COHORT.

scientific article published on 31 May 2017

DIPG-39. UNCOUPLING CAR T CELL RECOGNITION FROM TUMOR KILLING FOR DIPG THERAPY.

scientific article published on 22 June 2018

DIPG-69. CHARACTERISTICS OF PATIENTS ≥ 10 YEARS OF AGE WITH DIFFUSE INTRINSIC PONTINE GLIOMA: A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

DIPG-70. CLINICAL, RADIOLOGICAL, PATHOLOGICAL AND MOLECULAR CHARACTERISTICS OF CHILDREN <3 YEARS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): A REPORT FROM THE INTERNATIONAL DIPG REGISTRY

DNA fragmentation simulation method (FSM) and fragment size matching improve aCGH performance of FFPE tissues

scientific article

DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the Pediatric Brain Tumor Consortium.

scientific article published on 4 November 2010

Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.

scientific article published on 30 August 2011

Development of a parent-report cognitive function item bank using item response theory and exploration of its clinical utility in computerized adaptive testing

scientific article

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.

scientific article published in April 2018

Diencephalic syndrome: a cause of failure to thrive and a model of partial growth hormone resistance.

scientific article

Differences in molecular genetics between pediatric and adult malignant astrocytomas: age matters.

scientific article

Differences in vasculature between pilocytic and anaplastic astrocytomas of childhood

scientific article

Diffuse intrinsic pontine glioma: a reassessment

scientific article published on 03 May 2014

Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development.

scientific article published in October 2007

Disseminated glioneuronal tumors occurring in childhood: treatment outcomes and BRAF alterations including V600E mutation.

scientific article published on 19 March 2016

Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes

scientific article published on 26 August 2016

Don't throw out the baby with the bathwater!

scientific article published in February 2005

Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis

journal article published in 2014

EPIDEMIOLOGY

scholarly article by A. P.-Y. Liu et al published 1 June 2014 in Neuro-Oncology

EPN-14PEDIATRIC EPENDYMOMA: MULTI-INSTITUTIONAL EXPERIENCE REVEALS POOR LONG-TERM OVERALL SURVIVAL DESPITE FAVORABLE FIVE-YEAR OUTCOMES.

scientific article published on 30 May 2016

EPT-14PHASE I STUDY OF GENE MEDIATED CYTOTOXIC IMMUNOTHERAPY WITH AdV-tk AS ADJUVANT TO SURGERY AND RADIATION THERAPY FOR PEDIATRIC MALIGNANT GLIOMA AND RECURRENT EPENDYMOMA.

scientific article published on 30 May 2016

EPT-20CLINICAL TARGETED EXOME-BASED SEQUENCING IN COMBINATION WITH GENOME WIDE COPY NUMBER PROFILING: A CLIA CERTIFIED APPROACH FOR PRECISION MEDICINE IN 203 PEDIATRIC BRAIN TUMOR PATIENTS.

scientific article published on 30 May 2016

Efficacy and Safety of Dabrafenib in Pediatric Patients with BRAF V600 Mutation-Positive Relapsed or Refractory Low-Grade Glioma: Results from a Phase I/IIa Study

scientific article published on 01 December 2019

Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells

scientific article

Epigenetics in clinical management of children and adolescents with brain tumors

scientific article published on 3 February 2017

Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis

scientific article published on 3 April 2013

Epoxyeicosanoids promote organ and tissue regeneration.

scientific article published on 29 July 2013

Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice

scientific article published on 19 December 2011

Everyday cognitive function after craniopharyngioma in childhood.

scientific article published in January 2006

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

scientific article

Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma

scientific article published on 15 October 2010

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype

scientific article

Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome

scientific article published on 08 May 2019

FINAL RESULTS OF A PROSPECTIVE MULTI-INSTITUTIONAL PHASE II STUDY OF EVEROLIMUS (RAD001), AN MTOR INHIBITOR, IN PEDIATRIC PATIENTS WITH RECURRENT OR PROGRESSIVE LOW-GRADE GLIOMA. A POETIC CONSORTIUM TRIAL.

scientific article published in July 2014

Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors

scientific article

Future Clinical Trials in DIPG: Bringing Epigenetics to the Clinic

scientific article (publication date: 2015)

Future of clinical genomics in pediatric oncology.

scientific article published on 15 April 2013

GE-02CLINICAL TARGETED EXOME-BASED SEQUENCING FOR CHILDREN DIAGNOSED WITH BRAIN TUMORS: INITIAL RESULTS OF AN INSTITUTE-WIDE PROJECT ON PERSONALIZED MEDICINE.

scientific article

GE-05EXOME SEQUENCING REVEALS BRAF MUTATIONS IN PAPILLARY CRANIOPHARYNGIOMAS.

scientific article

GENE-07. LIQUID BIOPSY DETECTION OF GENOMIC ALTERATIONS IN PEDIATRIC BRAIN TUMORS FROM CELL-FREE DNA IN PERIPHERAL BLOOD, CSF, AND URINE

scientific article published on 23 April 2019

GENE-09. PRECISION MEDICINE ANALYSIS OF 203 PEDIATRIC BRAIN TUMORS REVEALS CLINICALLY RELEVANT GENOMIC ALTERATIONS.

scientific article published on 31 May 2017

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

scientific article

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

scientific article published on 30 April 2013

Gliomatosis cerebri: A consensus summary report from the First International Gliomatosis cerebri Group Meeting, March 26-27, 2015, Paris, France

scientific article

HG-109CONTEMPORARY SURVIVAL ENDPOINTS: AN INTERNATIONAL DIFFUSE INTRINSIC PONTINE GLIOMA REGISTRY STUDY.

scientific article published on 30 May 2016

HG-110SINGLE-CELL TRANSCRIPTOME ANALYSIS IN PEDIATRIC HEMISPHERIC AND MIDLINE HIGH-GRADE GLIOMAS.

scientific article published on 30 May 2016

HG-73SAFETY AND FEASIBILITY OF A MULTI-INSTITUTIONAL PHASE II TRIAL INCOPORATING BIOPSY AND MOLECULARLY DETERMINED TREATMENT OF CHILDREN AND YOUNG ADULTS WITH NEWLY DIAGNOSED DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPG).

scientific article published on 30 May 2016

HG-75CLINICAL, RADIOLOGICAL, AND HISTO-GENETIC CHARACTERISTICS OF LONG-TERM SURVIVORS OF DIFFUSE INTRINSIC PONTINE GLIOMA: A COLLABORATIVE REPORT FROM THE INTERNATIONAL AND SIOP-E DIPG REGISTRIES.

scientific article published on 30 May 2016

HG-93CONCURRENT USE OF PANOBINOSTAT AND RE-IRRADIATION IN CHILDREN WITH PROGRESSIVE DIPG: REPORT OF 2 CASES. ⬇️

scientific article published on 30 May 2016

Hutchinson-Gilford progeria is a skeletal dysplasia

scientific article published on July 2011

IMMU-04. IMMUNOPHENOTYPING OF PEDIATRIC BRAIN TUMORS: CORRELATING IMMUNE INFILTRATE WITH HISTOLOGY, MUTATIONAL LOAD, AND SURVIVAL AND ASSESSING CLONAL T CELL RESPONSE

IMMU-08. IMMUNOPHENOTYPING OF PEDIATRIC BRAIN TUMORS: CORRELATING IMMUNE INFILTRATE WITH HISTOLOGY, MUTATIONAL LOAD, AND SURVIVAL.

scientific article published on 31 May 2017

IMMU-13. A FAILURE TO RESOLVE INFLAMMATION: ROLE OF RESOLVINS IN THE TREATMENT OF PEDIATRIC CNS TUMORS.

scientific article published on 22 June 2018

IMMU-23. IMMUNOPHENOTYPING OF PEDIATRIC BRAIN TUMORS: CORRELATING IMMUNE INFILTRATE WITH HISTOLOGY, MUTATIONAL LOAD, AND SURVIVAL AND ASSESSING CLONAL T CELL RESPONSE.

scientific article published on 31 May 2017

INNV-22. LIQUID BIOPSY DETECTION OF GENOMIC ALTERATIONS IN PEDIATRIC BRAIN TUMORS FROM CELL FREE DNA IN PERIPHERAL BLOOD, CSF, AND URINE

Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity

scientific article

Identification of fibroblast heterogeneity in the tumor microenvironment

scientific article published on 05 December 2006

Identification of novel biologic targets in the treatment of newly diagnosed diffuse intrinsic pontine glioma

scientific article published on January 2012

Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response.

scientific article

Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.

scientific article

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

scientific article

Increasing value of autopsies in patients with brain tumors in the molecular era

scientific article published on 30 September 2019

Inhibition of neuroblastoma cell proliferation with omega-3 fatty acids and treatment of a murine model of human neuroblastoma using a diet enriched with omega-3 fatty acids in combination with sunitinib.

scientific article published on 21 December 2011

Inhibition of tumor angiogenesis by oral etoposide.

scientific article

Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome

scientific article

Innovative therapies for pediatric brain tumors

scientific article

Intensive Multimodality Treatment for Children With Newly Diagnosed CNS Atypical Teratoid Rhabdoid Tumor

scientific article (publication date: 20 January 2009)

LG-02MYB-QKI REARRANGEMENTS IN ANGIOCENTRIC GLIOMA DRIVE TUMORIGENICITY THROUGH A TRIPARTITE MECHANISM.

scientific article published on 30 May 2016

LG-03RADIATION THERAPY IS ASSOCIATED WITH INCREASED LATE MORTALITY IN LONG-TERM ADULT SURVIVORS OF CHILDHOOD LOW GRADE GLIOMA: A POPULATION BASED STUDY.

scientific article published on 21 April 2015

LG-46INFERIOR OUTCOME AND POOR RESPONSE TO CONVENTIONAL THERAPIES IN PEDIATRIC LOW-GRADE GLIOMAS HARBORING THE BRAF V600E MUTATION.

scientific article published on 30 May 2016

LG-47TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS.

scientific article published on 30 May 2016

LG-66CLINICAL AND TREATMENT FACTORS DETERMINING LONG-TERM OUTCOMES FOR ADULT SURVIVORS OF CHILDHOOD LOW-GRADE GLIOMA: A POPULATION-BASED STUDY.

scientific article published on 30 May 2016

LGG-05. SINGLE CELL RNA SEQUENCING REVEALS MITOGENIC AND PROGENITOR GENE PROGRAMS IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMAS

scientific article published on 23 April 2019

LGG-05. SINGLE-CELL RNA SEQUENCING OF PEDIATRIC LOW-GRADE GLIOMAS REVEALS INTRATUMORAL HETEROGENEITY.

scientific article

LGG-13. RESOLVING TRANSCRIPTIONAL PROFILES IN BRAF-REARRANGED PILOCYTIC ASTROCYTOMA USING SINGLE CELL RNA SEQUENCING

scientific article published on 22 June 2018

LGG-26. TYPE II BRAF INHIBITOR TAK-580 SHOWS PROMISE FOR UPCOMING CLINAL TRIAL AS EVIDENCED BY SINGLE PATIENT IND STUDY

scientific article published on 22 June 2018

LGG-44. A PHASE I DOSE ESCALATION TRIAL OF THE MEK1/2 INHIBITOR MEK162 (BINIMETINIB) IN CHILDREN WITH LOW-GRADE GLIOMAS AND OTHER RAS/RAF PATHWAY-ACTIVATED TUMORS

LGG-46. TRAMETINIB THERAPY IN PEDIATRIC PATIENTS WITH LOW-GRADE GLIOMAS (LGG) WITH BRAF GENE FUSION; A DISEASE-SPECIFIC COHORT IN THE FIRST PEDIATRIC TESTING OF TRAMETINIB

LOW GRADE GLIOMAS

Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas

scientific article published on 19 January 2011

Long-term clinical outcomes following treatment of childhood craniopharyngioma.

scientific article published on December 2010

Long-term neuropsychological follow-up of young children with medulloblastoma treated with sequential high-dose chemotherapy and irradiation sparing approach

scientific article published on 12 April 2017

Long-term outcome of 4,040 children diagnosed with pediatric low-grade gliomas: an analysis of the Surveillance Epidemiology and End Results (SEER) database

scientific article

Long-term visual outcomes of optic pathway gliomas in pediatric patients without neurofibromatosis type 1.

scientific article published on 16 June 2016

Lymphocyte homing.

scientific article

MB-52RESPONSE ASSESSMENT IN PEDIATRIC NEURO-ONCOLOGY (RAPNO) COMMITTEE GUIDELINES FOR RESPONSE ASSESSMENT IN MEDULLOBLASTOMA AND OTHER LEPTOMENINGEAL SEEDING TUMORS.

scientific article published on 30 May 2016

MB-66PILOT STUDY OF A SURGERY AND CHEMOTHERAPY-ONLY APPROACH IN THE UPFRONT THERAPY OF CHLDREN WITH Wnt POSITIVE STANDARD RISK MEDULLOBLASTOMA.

scientific article published on 30 May 2016

MB-70MEMMAT - A PHASE II STUDY OF METRONOMIC AND TARGETED ANTI-ANGIOGENESIS THERAPY FOR CHILDREN WITH RECURRENT/PROGRESSIVE MEDULLOBLASTOMA.

scientific article published on 30 May 2016

MBCL-02. CURRENT ISSUES IN THE MANAGEMENT OF DESMOPLASTIC NODULAR MEDULLOBLASTOMA IN YOUNG CHILDREN

MEDICAL AND NEURO-ONCOLOGY

scientific article published on 21 October 2011

MEDU-37. NEURONAL DIFFERENTIATION AND CELL-CYCLE PROGRAMS MEDIATE RESPONSE AND RESISTANCE TO BET-BROMODOMAIN INHIBITION IN MYC-DRIVEN MEDULLOBLASTOMA

MEDULLOBLASTOMA

MR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma

scientific article published on 07 May 2020

MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

scientific article

Marked regression of metastatic pilocytic astrocytoma during treatment with imatinib mesylate (STI-571, Gleevec): a case report and laboratory investigation

scientific article published in August 2003

Mechanism of pulmonary vein stenosis in infants with normally connected veins

scientific article published on 01 September 2000

Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome

scientific article published on 14 November 2011

Medical, psychological, cognitive and educational late-effects in pediatric low-grade glioma survivors treated with surgery only.

scientific article published on September 2009

Metachronous mediastinal seminoma occurring after intracranial germinoma in an adolescent

scientific article published on 01 November 2009

Metronomic antiangiogenic therapy in children with recurrent brain tumours of different histologies

Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome

scientific article published on 19 February 2018

Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells

scientific article published on 19 August 2019

Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007

scientific article published on 01 May 2008

Moving forward with metronomic chemotherapy: meeting report of the 2nd International Workshop on Metronomic and Anti-Angiogenic Chemotherapy in Paediatric Oncology.

scientific article

Moyamoya following cranial irradiation for primary brain tumors in children.

scientific article published in March 2007

Multiparametric Analysis of Permeability and ADC Histogram Metrics for Classification of Pediatric Brain Tumors by Tumor Grade.

scientific article published on 4 January 2018

Multiplexed Immunofluorescence Reveals Potential PD-1/PD-L1 Pathway Vulnerabilities in Craniopharyngioma.

scientific article published on 2 March 2018

Myelopoiesis in the zebrafish, Danio rerio.

scientific article published in August 2001

Myxopapillary ependymomas in children: imaging, treatment and outcomes

scientific article published on 14 October 2015

NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.

scientific article published on 10 January 2007

NS-26THE ROLE OF SURGERY IN NON-NF-ASSOCIATED PEDIATRIC OPTIC PATHWAY GLIOMAS (OPG) - IS THERE A NEW PARADIGM?

scientific article published on 30 May 2016

Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment

scientific article

Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma

scientific article published on 03 June 2019

Neuropsychological functioning after surgery in children treated for brain tumor

scientific article published in June 2003

Neutralization of Circulating Vascular Endothelial Growth Factor (VEGF) by Anti-VEGF Antibodies and Soluble VEGF Receptor 1 (sFlt-1) Induces Proteinuria

scientific article published in Journal of Biological Chemistry

New Classification for Central Nervous System Tumors: Implications for Diagnosis and Therapy

scientific article published on January 2017

New approaches to progeria

scientific article published on October 2007

New strategies in pediatric gliomas: molecular advances in pediatric low-grade gliomas as a model

scientific article published on 23 July 2013

Next generation metronomic chemotherapy-report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6-8 May 2016, Mumbai.

scientific article

Ophthalmologic Features of Progeria

scientific article published on 26 July 2017

Outcome of pediatric pineoblastoma after surgery, radiation and chemotherapy.

scientific article published on 16 April 2008

PATH-17. INCREASING VALUE OF AUTOPSIES IN PATIENTS WITH BRAIN TUMORS IN THE MOLECULAR ERA

PCLN-07. A 3D HYDROGEL CULTURE SYSTEM FACILITATES STUDY OF PRIMARY PEDIATRIC LOW-GRADE GLIOMA CELLS IN VITRO

scientific article published on 22 June 2018

PDCT-03. PHASE 1 STUDY OF Ad-RTS-hIL-12 + VELEDIMEX IN PEDIATRIC BRAIN TUMORS

PDCT-20. FEASIBILITY AND SAFETY OF SURGICAL BIOPSY FOR PATIENTS WITH DIPG: PRELIMINARY RESULTS FROM DIPG-BATS

scientific article published on 6 November 2017

PDCT-24. A PHASE I DOSE ESCALATION TRIAL OF THE MEK1/2 INHIBITOR MEK162 (BINIMETINIB) IN CHILDREN WITH LOW-GRADE GLIOMAS AND OTHER RAS-RAF PATHWAY-ACTIVATED TUMORS: INITIAL REPORT

PDTM-04. REDEFINING THE CELLULAR ARCHITECTURE OF DIFFUSE MIDLINE GLIOMAS WITH H3 K27M MUTATIONS THROUGH LARGE-SCALE SINGLE-CELL ANALYSES

PDTM-06. ALK AMPLIFICATION AND REARRANGEMENTS ARE RECURRENT TARGETABLE EVENTS IN GLIOBLASTOMA

scientific article published on 5 November 2018

PHASE I INDIVIDUAL DOSE TITRATION TRIAL OF THE HUMAN CORTICOTROPIN-RELEASING FACTOR (HCRF), CORTICORELIN ACETATE INJECTION (XERECEPT) IN PEDIATRIC PATIENTS WITH PERITUMORAL EDEMA OF THE BRAIN.

scientific article published in July 2014

PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition.

scholarly article

PPARalpha deficiency in inflammatory cells suppresses tumor growth

scientific article

PPARgamma as a therapeutic target for tumor angiogenesis and metastasis

scientific article

PPARs: A Double-Edged Sword in Cancer Therapy?

scientific article published in January 2008

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

scientific article published on 01 February 2022

Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration

scientific article published on 17 July 2020

Paediatric Strategy Forum for medicinal product development of epigenetic modifiers for children: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration

scientific article published on 25 September 2020

Parent-perceived child cognitive function: results from a sample drawn from the US general population

scientific article published on 23 July 2010

Paucicellular Fibrointimal Proliferation Characterizes Pediatric Pulmonary Vein Stenosis: Clinicopathologic Analysis of 213 Samples From 97 Patients

scientific article

Pediatric Low-Grade Gliomas: Next Biologically Driven Steps

scientific article published on 2 August 2017

Pediatric brainstem gliomas: new understanding leads to potential new treatments for two very different tumors.

scientific article

Pediatric cancer research: Surviving COVID-19

scientific article published on 18 June 2020

Pediatric high-grade glioma: biologically and clinically in need of new thinking

scientific article

Pediatric low-grade gliomas: how modern biology reshapes the clinical field

scientific article

Pediatric low-grade gliomas: implications of the biologic era.

scientific article published on 28 September 2016

Pediatric neuro-oncology: current status and future directions.

scientific article published on 18 June 2012

Perfusion MRI of U87 brain tumors in a mouse model

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Phase I clinical trial of cilengitide in children with refractory brain tumors: Pediatric Brain Tumor Consortium Study PBTC-012.

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Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report

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Phase II trial of pirfenidone in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.

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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases

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Prospective Feasibility and Safety Assessment of Surgical Biopsy for Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma.

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Pubertal Progression in Adolescent Females with Progeria.

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Pulmonary vein stenosis: expression of receptor tyrosine kinases by lesional cells

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Rethinking childhood ependymoma: a retrospective, multi-center analysis reveals poor long-term overall survival.

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Single-agent erlotinib versus oral etoposide in patients with recurrent or refractory pediatric ependymoma: a randomized open-label study.

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Sleep dysfunction in long term survivors of craniopharyngioma

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TR-14A FEASIBILITY AND RANDOMIZED PHASE II STUDY OF VORINOSTAT, BEVACIZUMAB, OR TEMOZOLOMIDE DURING RADIATION FOLLOWED BY MAINTENANCE CHEMOTHERAPY IN NEWLY-DIAGNOSED PEDIATRIC HIGH-GRADE GLIOMA: CHILDREN'S ONCOLOGY GROUP STUDY ACNS0822.

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TRTH-23. FEASIBILITY AND SAFETY OF SURGICAL BIOPSY FOR PATIENTS WITH DIPG: PRELIMINARY RESULTS FROM DIPG-BATS.

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TUMOUR BIOLOGY

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Treatment of low-grade gliomas in children: an update.

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ZD6474, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptor and epidermal growth factor receptor, inhibits tumor growth of multiple nervous system tumors

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