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List of works by Ian S Blagbrough

An HPLC assay for the norditerpenoid alkaloid methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist

scientific article published in November 1995

An autoradiographic study of the distribution of binding sites for the novel alpha7-selective nicotinic radioligand [3H]-methyllycaconitine in the mouse brain

scientific article published in August 1999

Animal models for target diseases in gene therapy--using DNA and siRNA delivery strategies.

scientific article published on 08 October 2008

Arthropod toxins as leads for novel insecticides: an assessment of polyamine amides as glutamate antagonists

scientific article published in March 1992

Asymmetrical N4,N9-diacyl spermines: SAR studies of nonviral lipopolyamine vectors for efficient siRNA delivery with silencing of EGFP reporter gene.

scientific article published on 6 June 2012

Biosynthesis of scopoletin and scopolin in cassava roots during post-harvest physiological deterioration: the E-Z-isomerisation stage

scientific article published on 10 November 2008

Cassava: an appraisal of its phytochemistry and its biotechnological prospects.

scientific article published on 11 October 2010

Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling alpha 7-type neuronal nicotinic acetylcholine receptors

scientific article published in May 1999

Constituents and secondary metabolite natural products in fresh and deteriorated cassava roots

scientific article published in April 2010

Conversion of the sodium channel activator aconitine into a potent alpha 7-selective nicotinic ligand

scientific article published in May 1995

DNA binding of a spermine derivative: spectroscopic study of anthracene-9-carbonyl-N1-spermine with poly[d(G-C).(d(G-C)] and poly[d(A-T).d(A-T)]

scientific article published on 01 December 1994

Design and synthesis of N4,N9-disubstituted spermines for non-viral siRNA delivery--structure-activity relationship studies of siFection efficiency versus toxicity.

scientific article published on 9 October 2008

Differential inhibition of Ca2+ channels in mature rat cerebellar Purkinje cells by sFTX-3.3 and FTX-3.3.

scientific article

Effect of spermine conjugation on the cytotoxicity and cellular transport of acridine.

scientific article published on November 2002

Efficient Silencing of EGFP Reporter Gene with siRNA Delivered by Asymmetrical N4,N9-Diacyl Spermines ⬇️

scientific article published on June 6, 2012

Efficient calf thymus DNA condensation upon binding with novel bile acid polyamine amides

scientific article

Extracellular or intracellular application of argiotoxin-636 has inhibitory actions on membrane excitability and voltage-activated currents in cultured rat sensory neurones

scientific article

High-performance liquid chromatographic determination of naproxen, ibuprofen and diclofenac in plasma and synovial fluid in man

scientific article published on July 24, 1992

Human renal C-S lyase: structure-activity relationships of cytosolic and mitochondrial enzymes

scientific article published in September 1990

Human renal C-S lyases: two cytosolic isoenzymes

scientific article published in September 1990

Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110delta-dependent mechanism

scientific article

Investigation of biosynthetic pathways to hydroxycoumarins during post-harvest physiological deterioration in Cassava roots by using stable isotope labelling

scientific article published in December 2008

Iron uptake in Pseudomonas aeruginosa mediated by N-(2,3-dihydroxybenzoyl)-L-serine and 2,3-dihydroxybenzoic acid

scientific article published on 01 March 1995

Kynurenine aminotransferase activity in human liver: identity with human hepatic C-S lyase activity and a physiological role for this enzyme

scientific article published in May 1992

Lipopolyamine-mediated single nanoparticle formation of calf thymus DNA analyzed by fluorescence correlation spectroscopy.

scientific article published on 21 June 2006

Lipopolyamines incorporating the tetraamine spermine, bound to an alkyl chain, sequester bacterial lipopolysaccharide

scientific article published on September 2000

Multiple DNA binding modes of anthracene-9-carbonyl-N1-spermine

scientific article published on 01 June 1995

N1,N12-Diacyl spermines: SAR studies on non-viral lipopolyamine vectors for plasmid DNA and siRNA formulation.

scientific article published on 30 October 2009

N4,N9-dioleoyl spermine is a novel nonviral lipopolyamine vector for plasmid DNA formulation.

scientific article published on 8 June 2005

Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal alpha-bungarotoxin binding sites: importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine receptor binding

scientific article published in November 1996

Polyamine FTX-3.3 and polyamine amide sFTX-3.3 inhibit presynaptic calcium currents and acetylcholine release at mouse motor nerve terminals

scientific article published on February 1997

Quantitative HPLC analysis of mebeverine, mesalazine, sulphasalazine and dispersible aspirin stored in a Venalink monitored dosage system with co-prescribed medicines

scientific article published on 14 October 2010

Quantitative silencing of EGFP reporter gene by self-assembled siRNA lipoplexes of LinOS and cholesterol

scientific article published on 25 October 2012

Rapid and sensitive ethidium bromide fluorescence quenching assay of polyamine conjugate-DNA interactions for the analysis of lipoplex formation in gene therapy

scientific article published in June 2000

Synthesis of cholesteryl polyamine carbamates: pK(a) studies and condensation of calf thymus DNA.

scientific article published in May 2000

The regiochemical distribution of positive charges along cholesterol polyamine carbamates plays significant roles in modulating DNA binding affinity and lipofection

scientific article

Varying the unsaturation in N4,N9-dioctadecanoyl spermines: nonviral lipopolyamine vectors for more efficient plasmid DNA formulation.

scientific article published on January 2006

Very long chain N4, N9 -diacyl spermines: non-viral lipopolyamine vectors for efficient plasmid DNA and siRNA delivery

scientific article published on 10 September 2008

[3H]-Methyllycaconitine: a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors

scientific article published on April 2001

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