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List of works by Mads Gyrd-Hansen

A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production

scientific article

A new functional assay for the diagnosis of X-linked inhibitor of apoptosis (XIAP) deficiency.

scientific article published in June 2014

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

scientific article

Attenuation of cGAS-STING signaling is mediated by a p62/SQSTM1-dependent autophagy pathway activated by TBK1.

scientific article published in March 2018

Breast cancer cells with acquired antiestrogen resistance are sensitized to cisplatin-induced cell death

scientific article

Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling

scientific article published on 03 February 2021

Diarylurea compounds inhibit caspase activation by preventing the formation of the active 700-kilodalton apoptosome complex

scientific article published on November 2003

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

scientific article published on July 2013

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain infection

scientific article published on 01 July 2020

Heat shock protein 70 promotes cell survival by inhibiting lysosomal membrane permeabilization

scientific article published on August 2004

Heregulin-induced epigenetic regulation of the utrophin-A promoter

scientific article

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

scientific article published on 19 October 2008

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

scientific article

Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.

scientific article

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

scientific article published on 02 July 2020

JNK2 mediates TNF-induced cell death in mouse embryonic fibroblasts via regulation of both caspase and cathepsin protease pathways

scientific article published in March 2004

Met1-linked ubiquitination in immune signalling

scientific article

Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response

scientific article published in 2024

Molecular Basis and Regulation of OTULIN-LUBAC Interaction

scientific article

OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

scientific article

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

scientific article

Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains

scientific article published on 01 October 2021

Sensitization to the lysosomal cell death pathway upon immortalization and transformation

scientific article published on August 2004

Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling

scientific article published on 19 July 2018

Sp1 and the ets-related transcription factor complex GABP alpha/beta functionally cooperate to activate the utrophin promoter

scientific article published in May 2002

Symptomatic males and female carriers in a large Caucasian kindred with XIAP deficiency

scientific article published on 6 May 2015

The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

article

X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis.

scientific article published on 31 July 2013

XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation

scientific article published on 29 May 2014

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