List of works - Anatoli Meriin

A first order phase transition mechanism underlies protein aggregation in mammalian cells

scientific article published on 04 February 2019

A novel approach to recovery of function of mutant proteins by slowing down translation.

scientific article

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo

scientific article

Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

scientific article published on 14 October 2008

Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis

scientific article published on November 2003

Association of translation factor eEF1A with defective ribosomal products generates a signal for aggresome formation ⬇️

scientific article published on February 22, 2012

Characterization of proteins associated with polyglutamine aggregates: a novel approach towards isolation of aggregates from protein conformation disorders

scientific article published on 16 April 2007

Endocytosis machinery is involved in aggregation of proteins with expanded polyglutamine domains

scientific article

Heat Shock Protein 70 Protects from Caspase-Independent Programmed Cell Death via Suppression of Stress Kinase JNK

scientific article published on 12 October 2001

Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance

scientific article published on 01 July 1997

Hsp70-Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation

article published in the Proceedings of the National Academy of Sciences of the United States of America

Inhibition of influenza M2-induced cell death alleviates its negative contribution to vaccination efficiency

scientific article

Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1.

scientific article

Isolation of aggresomes and other large aggregates

scientific article

Prime-boost vaccination with a combination of proteosome-degradable and wild-type forms of two influenza proteins leads to augmented CTL response.

scientific article published on 14 March 2008

Proteasome failure promotes positioning of lysosomes around the aggresome via local block of microtubule-dependent transport

scientific article

Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis

scientific article published on 01 March 1998

Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72.

scientific article

RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils.

scientific article

Suppression of stress kinase JNK is involved in HSP72-mediated protection of myogenic cells from transient energy deprivation. HSP72 alleviates the stewss-induced inhibition of JNK dephosphorylation

scientific article published on December 2000

The function of HSP72 in suppression of c-Jun N-terminal kinase activation can be dissociated from its role in prevention of protein damage

scientific article published on 01 July 1999

The heat shock transcription factor Hsf1 is downregulated in DNA damage-associated senescence, contributing to the maintenance of senescence phenotype.

scientific article

Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1

scientific article

List of works by Anatoli Meriin

A first order phase transition mechanism underlies protein aggregation in mammalian cells

A novel approach to recovery of function of mutant proteins by slowing down translation.

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo

Abnormal proteins can form aggresome in yeast: aggresome-targeting signals and components of the machinery

Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis

Association of translation factor eEF1A with defective ribosomal products generates a signal for aggresome formation ⬇️

Characterization of proteins associated with polyglutamine aggregates: a novel approach towards isolation of aggregates from protein conformation disorders

Endocytosis machinery is involved in aggregation of proteins with expanded polyglutamine domains

Heat Shock Protein 70 Protects from Caspase-Independent Programmed Cell Death via Suppression of Stress Kinase JNK

Hsp70 prevents activation of stress kinases. A novel pathway of cellular thermotolerance

Hsp70-Bag3 complex is a hub for proteotoxicity-induced signaling that controls protein aggregation

Inhibition of influenza M2-induced cell death alleviates its negative contribution to vaccination efficiency

Intracellular aggregation of polypeptides with expanded polyglutamine domain is stimulated by stress-activated kinase MEKK1.

Isolation of aggresomes and other large aggregates

Prime-boost vaccination with a combination of proteosome-degradable and wild-type forms of two influenza proteins leads to augmented CTL response.

Proteasome failure promotes positioning of lysosomes around the aggresome via local block of microtubule-dependent transport

Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis

Protein-damaging stresses activate c-Jun N-terminal kinase via inhibition of its dephosphorylation: a novel pathway controlled by HSP72.

RuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils.

Suppression of stress kinase JNK is involved in HSP72-mediated protection of myogenic cells from transient energy deprivation. HSP72 alleviates the stewss-induced inhibition of JNK dephosphorylation

The function of HSP72 in suppression of c-Jun N-terminal kinase activation can be dissociated from its role in prevention of protein damage

The heat shock transcription factor Hsf1 is downregulated in DNA damage-associated senescence, contributing to the maintenance of senescence phenotype.

Triggering aggresome formation. Dissecting aggresome-targeting and aggregation signals in synphilin 1