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List of works by Andrew J. McLachlan

A Comparison of Peripheral and Centrally Collected Cyclosporine A Blood Levels in Pediatric Patients Undergoing Stem Cell Transplant

scientific article published on 19 January 2005

A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia

scientific article published on 20 November 2014

A Strategy to Refine the Phenotyping Approach and Its Implementation to Predict Drug Clearance: A Physiologically Based Pharmacokinetic Simulation Study

scientific article published on 24 October 2018

A high-throughput assay using liquid chromatography-tandem mass spectrometry for simultaneous in vivo phenotyping of 5 major cytochrome p450 enzymes in patients

scientific article published in April 2009

A pharmacometric approach to investigate the impact of methylxanthine abstinence and caffeine consumption on CYP1A2 activity

scientific article published on 30 August 2013

A phase I study of the pharmacokinetics and safety of passive immunotherapy with caprine anti-HIV antibodies, (PE)HRG214, in HIV-1-infected individuals

scientific article

A retrospective study of drug‐related problems in Australian aged care homes: medication reviews involving pharmacists and general practitioners ⬇️

scientific article published on 02 September 2010

Absorption and in vivo dissolution of hydroxycholoroquine in fed subjects assessed using deconvolution techniques.

scientific article

Adherence, persistence and continuation with cholinesterase inhibitors in Alzheimer's disease

scientific article published on 4 September 2011

Adverse selection? A multi-dimensional profile of people dispensed opioid analgesics for persistent non-cancer pain

scientific article

Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats

scientific article

Aging biology and novel targets for drug discovery

scientific article

Aging, Drugs, and Drug Metabolism

scientific article published on 18 July 2011

Amphotericin B Dose Optimization in Children with Malignant Diseases

scientific article published on 19 February 2007

An Electronic Clinical Decision Support System for the Management of Low Back Pain in Community Pharmacy: Development and Mixed Methods Feasibility Study

scientific article published on 11 May 2020

An update on ethnic differences in drug metabolism and toxicity from anti-cancer drugs.

scientific article published on 28 September 2011

Analytical validation for a series of marker compounds used to assess renal drug elimination processes

scientific article

Anticholinergic activity of commonly prescribed medications and neuropsychiatric adverse events in older people.

scientific article published in October 2009

Application of a high-performance liquid chromatographic assay for the neuromuscular blocker gallamine to analysis of rat plasma, muscle and microdialysate samples

scientific article

Assessment of diclofenac or spinal manipulative therapy, or both, in addition to recommended first-line treatment for acute low back pain: a randomised controlled trial

scientific article

Assessment of in vitro and in vivo recovery of gallamine using microdialysis

scientific article published on 01 November 2000

Atrial fibrillation screening in pharmacies using an iPhone ECG: a qualitative review of implementation

scientific article

Authors’ reply to the comment by Durg

scientific article published on 01 February 2017

Beyond Conventional Cancer Treatments: "The Use of Complementary Therapies During Cancer Treatment: Implications for Clinicians"

Bioavailability of hydroxychloroquine tablets in patients with rheumatoid arthritis

scientific article published on March 1994

Caffeine and paraxanthine HPLC assay for CYP1A2 phenotype assessment using saliva and plasma.

scientific article

Can predictors of response to NSAIDs be identified in patients with acute low back pain?

scientific article published on October 2009

Cardiovascular disease risk factor assessment and management in gout: an analysis using guideline-based electronic clinical decision support.

scientific article published on 7 November 2008

Changes in tacrolimus distribution in blood and plasma protein binding following liver transplantation

scientific article published in October 2004

Characterizing specialized compounding in community pharmacies

scientific article published on 6 August 2011

Clinical importance of the CYP2C19*17 variant allele for voriconazole

scientific article published on January 2011

Clinical pharmacokinetics and pharmacodynamics of allopurinol and oxypurinol

scientific article

Clinical pharmacology in the geriatric patient

scientific article published on June 2007

Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment

scientific article

Clinical pharmacology of analgesics in old age and frailty

scholarly article by Sarah J Mitchell et al published May 2009 in Reviews in Clinical Gerontology

Clinical pharmacology of chemotherapy agents in older people with cancer

scientific article

Community pharmacy compounding-impact on professional status.

scientific article published on 30 March 2011

Community pharmacy services to optimise the use of medications for mental illness: a systematic review.

scientific article

Comparative efficacy trials with no placebo group cannot determine efficacy

scientific article published in the British Medical Journal

Comparison of the pharmacokinetics of two von Willebrand factor concentrates [Biostate and AHF (High Purity)] in people with von Willebrand disorder

scientific article published on 01 June 2007

Considering CYP1A2 phenotype and genotype for optimizing the dose of olanzapine in the management of schizophrenia.

scientific article published on 04 May 2013

Consumer perspectives of medication-related problems following discharge from hospital in Australia: a quantitative study

scientific article

Correction to: Deprescribing Opioids in Chronic Non‑cancer Pain: Systematic Review of Randomised Trials

scientific article published on 29 September 2020

Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions.

scientific article published on 4 August 2017

Cyclosporin C(2) and C(0) concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors

scientific article published in July 2003

Cytochrome P450 2B6 activity as measured by bupropion hydroxylation: effect of induction by rifampin and ethnicity

scientific article published in July 2006

Decision support tool to individualize cyclosporine dose in stable, long-term heart transplant recipients receiving metabolic inhibitors: overcoming limitations of cyclosporine C2 monitoring

scientific article published in October 2006

Deprescribing Opioids in Chronic Non-cancer Pain: Systematic Review of Randomised Trials

scientific article published on 31 July 2020

Determinants of antipsychotic medication use among older people living in aged care homes in Australia

scientific article published in May 2010

Development of a sufficient design for estimation of fluconazole pharmacokinetics in people with HIV infection.

scientific article published on 28 June 2008

Disposition and absorption of hydroxychloroquine enantiomers following a single dose of the racemate.

scientific article published on January 1994

Disposition of amphotericin B in the isolated perfused rat liver

scientific article published in January 2004

Diurnal variation in CYP1A2 enzyme activity in South Asians and Europeans.

scientific article

Dosing Errors: Age-Related Changes in Pharmacokinetics

Drug metabolism in older people--a key consideration in achieving optimal outcomes with medicines.

scientific article published on 10 August 2011

Drug-related problems in the community setting: pharmacists' findings and recommendations for people with mental illnesses.

scientific article published on January 2006

E-Health: what are we talking about?

article

Effect of Metabolic Inhibitors on Cyclosporine Pharmacokinetics Using a Population Approach

scientific article published on 01 August 1998

Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

scientific article published in May 2004

Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects

scientific article

Effectiveness of pharmacist-led medication reconciliation programmes on clinical outcomes at hospital transitions: a systematic review and meta-analysis

scientific article

Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide

scientific article

Efficacy and safety of paracetamol for spinal pain and osteoarthritis: systematic review and meta-analysis of randomised placebo controlled trials

scientific article

Efficacy and tolerability of muscle relaxants for low back pain: Systematic review and meta-analysis.

scientific article published on 22 June 2016

Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial.

scientific article published on 23 July 2014

Efficacy, Tolerability, and Dose-Dependent Effects of Opioid Analgesics for Low Back Pain: A Systematic Review and Meta-analysis

scientific article

Ethnic differences in drug metabolism and toxicity from chemotherapy

article

Evaluating the effectiveness of a peer-led education intervention to improve the patient safety attitudes of junior pharmacy students: a cross-sectional study using a latent growth curve modelling approach.

scientific article

Evidence and practice in the self-management of low back pain: findings from an Australian internet-based survey

scientific article published on July 2010

Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model.

scientific article published on 21 October 2013

Evidence-based toxicity evaluation and scheduling of Chinese herbal medicines.

scientific article published on 31 December 2012

Factors affecting variability in distribution of tacrolimus in liver transplant recipients

scientific article published in March 2004

Feasibility and cost-effectiveness of stroke prevention through community screening for atrial fibrillation using iPhone ECG in pharmacies. The SEARCH-AF study

scientific article published in April 2014

Frailty Should be Assessed Using Validated Scales

scientific article published on 01 August 2010

Gout, diabetes and cardiovascular disease in the Aotearoa New Zealand adult population: co-prevalence and implications for clinical practice

scientific article published on January 25, 2012

HPLC assay for bupropion and its major metabolites in human plasma

scientific article published in September 2005

HPLC-UV assay for monitoring total and unbound mycophenolic acid concentrations in children.

scientific article

Healthcare expenditure and its predictors in a cohort of Australians living with sciatica

scientific article published on 24 September 2020

Hepatic disposal of advanced glycation end products during maturation and aging.

scientific article published on 24 March 2013

Hepatobiliary disposition of liposomal amphotericin B in the isolated perfused rat liver

scientific article

Herbal medicines: challenges in the modern world. Part 1. Australia and New Zealand.

scientific article published on 12 April 2016

High melphalan exposure is associated with improved overall survival in myeloma patients receiving high dose melphalan and autologous transplantation

scientific article published on 15 February 2016

High risk prescribing in older adults: prevalence, clinical and economic implications and potential for intervention at the population level

scientific article

High-performance liquid chromatographic separation of the enantiomers of hydroxychloroquine and its major metabolites in biological fluids using an α1-acid glycoprotein stationary phase

scientific article published on 01 September 1991

High-risk prescribing and incidence of frailty among older community-dwelling men.

scientific article published in February 2012

Human subcutaneous tissue distribution of fluconazole: comparison of microdialysis and suction blister techniques

scientific article published in November 2003

Imatinib Disposition and ABCB1 (MDR1, P-Glycoprotein) Genotype

scientific article published on 09 May 2007

Impact of electronic medication reconciliation interventions on medication discrepancies at hospital transitions: a systematic review and meta-analysis

scientific article

Impact of residential medication management reviews on drug burden index in aged-care homes: a retrospective analysis.

scientific article published in January 2009

Impaired blockade of insulin-like growth factor I (IGF-I)-induced hypoglycemia by IGF binding protein-3 analog with reduced ternary complex-forming ability

scientific article published in May 2002

In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism

scientific article

In-vitro distribution of terbinafine in rat and human blood

scientific article published in February 2002

Influence of environmental and genetic factors on CYP1A2 activity in individuals of South Asian and European ancestry.

scientific article

Influence of genetic polymorphisms on the pharmacokinetics and pharmaco-dynamics of sulfonylurea drugs.

scientific article published on July 2009

Interpretation of chloroquine pharmacokinetic data

scientific article published on 01 January 1993

Interventions available over the counter and advice for acute low back pain: systematic review and meta-analysis

scientific article published on 14 October 2013

Investigating paracetamol pharmacokinetics using venous and capillary blood and saliva sampling

scientific article published on 07 February 2012

Investigating the Primary Care Management of Low Back Pain: A Simulated Patient Study

scientific article published on 05 October 2015

Investigation of herb-drug interactions with ginkgo biloba in women receiving hormonal treatment for early breast cancer.

scientific article published on 22 March 2013

Investigation of the Effects of Herbal Medicines on Warfarin Response in Healthy Subjects: A Population Pharmacokinetic-Pharmacodynamic Modeling Approach

scientific article published on 01 November 2006

Knowledge and attitudes regarding the personally controlled electronic health record: an Australian national survey.

scientific article published on April 2014

Knowledge and satisfaction of pharmacists attending an educational workshop on evidence-based management of low back pain

scientific article published on 7 May 2014

Loperamide inhibits the biliary excretion of irinotecan (CPT-11) in the rat isolated perfused liver.

scientific article published in January 2005

Low back pain and best practice care: A survey of general practice physicians

scientific article published in February 2010

Manipulative therapy and/or NSAIDs for acute low back pain: design of a randomized controlled trial [ACTRN012605000036617]

scientific article

Measurement of urinary oxypurinol by high performance liquid chromatography-tandem mass spectrometry

scientific article published on 29 July 2010

Measuring anticholinergic drug exposure in older community-dwelling Australian men: a comparison of four different measures

scientific article

Medication appropriateness tool for co-morbid health conditions in dementia: consensus recommendations from a multidisciplinary expert panel

scientific article published on 16 August 2016

Medication reconciliation as a medication safety initiative in Ethiopia: a study protocol

scientific article published on 24 November 2016

Medication withdrawal trials in people aged 65 years and older: a systematic review.

scientific article published on January 2008

Medicines and disease information needs of older Arabic-speaking Australians.

scientific article published on 4 April 2012

Mental health case conferences in primary care: content and treatment decision making.

scientific article published on March 2007

Misuse of Formulations in the Aged Care Setting

Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration.

scientific article

Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring

scientific article

Murine pharmacokinetics of rifapentine delivered as an inhalable dry powder

scientific article published on 16 December 2014

Muscle distribution of the neuromuscular blocker gallamine using microdialysis

scientific article published in March 2002

Nonsteroidal anti-inflammatory drugs (NSAIDs) in older people: Prescribing patterns according to pain prevalence and adherence to clinical guidelines

scientific article published on 20 June 2014

OPAL: a randomised, placebo-controlled trial of opioid analgesia for the reduction of pain severity in people with acute spinal pain. Trial protocol

scientific article published on 24 August 2016

Optimal sampling of antipsychotic medicines: a pharmacometric approach for clinical practice

scientific article

Optimizing azole antifungal therapy in the prophylaxis and treatment of fungal infections

scientific article published on December 2014

PACE--the first placebo controlled trial of paracetamol for acute low back pain: design of a randomised controlled trial

scientific article

PACE--the first placebo controlled trial of paracetamol for acute low back pain: statistical analysis plan.

scientific article published on 09 August 2013

PRECISE - pregabalin in addition to usual care for sciatica: study protocol for a randomised controlled trial.

scientific article published on 11 July 2013

PRECISE--pregabalin in addition to usual care: statistical analysis plan

scientific article published on 27 January 2016

Participation of pharmacists in clinical trial recruitment for low back pain

scientific article published on 8 August 2014

Patterns of platinum drug use in an acute care setting: a retrospective study

scientific article published on 22 May 2018

Pharmacists’ views on implementing a disease state management program for low back pain

scientific article published on 01 January 2016

Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in healthy subjects

scientific article

Pharmacokinetic and pharmacodynamic interaction between allopurinol and probenecid in patients with gout

scientific article

Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects

scientific article

Pharmacokinetic assessment of constituents of Boswellia serrata, pine bark extracts, curcumin in combination including methylsulfonylmethane in healthy volunteers

scientific article published on 13 October 2019

Pharmacokinetic considerations of regional administration and drug targeting: influence of site of input in target tissue and flux of binding protein

scientific article published in August 1996

Pharmacokinetics and Tissue Distribution of Cisplatin and Conjugates of Cisplatin with Carboxymethyldextran and A5B7 Monoclonal Antibody in CD1 Mice

scientific article published on 01 December 1997

Pharmacokinetics and cardiovascular effects following a single oral administration of a nonaqueous pimobendan solution in healthy dogs

scientific article published on 21 May 2015

Pharmacokinetics and pharmacodynamics of hydroxychloroquine enantiomers in patients with rheumatoid arthritis receiving multiple doses of racemate.

scientific article published on January 1994

Pharmacokinetics of caffeine in plasma and saliva, and the influence of caffeine abstinence on CYP1A2 metrics

scientific article published on 06 July 2011

Pharmacokinetics of chloramphenicol following administration of intravenous and subcutaneous chloramphenicol sodium succinate, and subcutaneous chloramphenicol, to koalas (Phascolarctos cinereus).

scientific article

Pharmacokinetics of ciprofloxacin in the human eye: a clinical study and population pharmacokinetic analysis

scientific article

Pharmacokinetics of cyclosporine in heart transplant recipients receiving metabolic inhibitors

scientific article published in April 2001

Pharmacometrics: an underused resource in Australian clinical research

article

Pharmacy-led medication reconciliation programmes at hospital transitions: a systematic review and meta-analysis

scientific article published on 23 February 2016

Physiologically Based Pharmacokinetic Modelling of Hyperforin to Predict Drug Interactions with St John's Wort

scientific article published on 01 July 2019

Physiologically based pharmacokinetic model for terbinafine in rats and humans

scientific article published on July 2002

Physiologically based pharmacokinetic modeling at the extremes of age.

scientific article published on 21 November 2012

Pilot study of milrinone for low systemic blood flow in very preterm infants

scientific article published in March 2006

Plasma protein binding of the enantiomers of hydroxychloroquine and metabolites

scientific article published on January 1993

Plasma protein distribution and its impact on pharmacokinetics of liposomal amphotericin B in paediatric patients with malignant diseases.

scientific article published on 19 December 2006

Poloxamer 407 increases the recovery of paracetamol in the isolated perfused rat liver

scientific article published on 16 June 2010

Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes

scientific article

Population Pharmacokinetics and Pharmacodynamics: An Underutilized Resource

Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients

scientific article published in August 2005

Population pharmacokinetics and dosing regimen design of milrinone in preterm infants

scientific article published on 11 May 2006

Population pharmacokinetics of acyclovir in children and young people with malignancy after administration of intravenous acyclovir or oral valacyclovir.

scientific article published on 4 May 2009

Population pharmacokinetics of liposomal amphotericin B in pediatric patients with malignant diseases

scientific article

Population pharmacokinetics of melphalan in patients with multiple myeloma undergoing high dose therapy.

scientific article

Population pharmacokinetics of mycophenolic acid in children and young people undergoing blood or marrow and solid organ transplantation

scientific article

Posaconazole exposure-response relationship: evaluating the utility of therapeutic drug monitoring

scientific article

Potential for pharmacokinetic interactions between Schisandra sphenanthera and bosutinib, but not imatinib: in vitro metabolism study combined with a physiologically-based pharmacokinetic modelling approach

scientific article published on 06 April 2020

Prediction of plasma caffeine concentrations in young adolescents following ingestion of caffeinated energy drinks: a Monte Carlo simulation

scientific article

Predictors of vinorelbine pharmacokinetics and pharmacodynamics in patients with cancer.

scientific article published in May 2006

Prescribing for Australians living with dementia: study protocol using the Delphi technique

scientific article

Principles and clinical application of assessing alterations in renal elimination pathways.

scientific article published on January 2003

Psychiatric Drug Use Among Patients of a Community Mental Health Service

article

Relationships Between Pharmacovigilance, Molecular, Structural, and Pathway Data: Revealing Mechanisms for Immune-Mediated Drug-Induced Liver Injury.

scientific article

Reply to "What types of Candida infections should be included when evaluating breakthrough infections during posaconazole prophylaxis?".

scientific article published in June 2013

Screening Education And Recognition in Community pHarmacies of Atrial Fibrillation to prevent stroke in an ambulant population aged >=65 years (SEARCH-AF stroke prevention study): a cross-sectional study protocol

scientific article

Single-dose pharmacokinetics and cardiovascular effects of oral pimobendan in healthy cats

scientific article published on 6 September 2016

Specialized compounding in community pharmacies: Organizational perspective

scientific article published on 01 May 2010

Statin use and clinical outcomes in older men: a prospective population-based study

scientific article published on 9 March 2013

Studies of the mechanism of crystal growth of hexamethylmelamine

Telaprevir and boceprevir: a potential role for therapeutic drug monitoring

scientific article

Terbinafine in combination with other antifungal agents for treatment of resistant or refractory mycoses: investigating optimal dosing regimens using a physiologically based pharmacokinetic model.

scientific article published on 14 October 2013

The Challenges of Treating Sciatica Pain in Older Adults

scientific article

The Effects of Cruciferous Vegetable-Enriched Diets on Drug Metabolism: A Systematic Review and Meta-Analysis of Dietary Intervention Trials in Humans

scientific article published on 22 February 2020

The Ethics of Prescribing Medications to Older People

The Need to Strengthen the Role of the Pharmacist in Sri Lanka: Perspectives

scientific article published on 05 June 2019

The economic burden of guideline-recommended first line care for acute low back pain.

scientific article

The effects of educational interventions on pharmacists’ knowledge, attitudes and beliefs towards low back pain

scientific article published on 08 April 2015

The efficacy of conservative treatment of osteoporotic compression fractures on acute pain relief: a systematic review with meta-analysis

scientific article published on March 2015

The experiences of implementing generic medicine policy in eight countries: A review and recommendations for a successful promotion of generic medicine use

scientific article

The impact of frailty on pharmacokinetics in older people: using gentamicin population pharmacokinetic modeling to investigate changes in renal drug clearance by glomerular filtration

scientific article published on 14 February 2014

The influence of old age and poloxamer-407 on the hepatic disposition of diazepam in the isolated perfused rat liver

scientific article published on 19 September 2012

The nature, severity and causes of medication incidents from an Australian community pharmacy incident reporting system: The QUMwatch study

scientific article published in 2021

The participation of cytochrome P450 3A4 in clozapine biotransformation is detected in people with schizophrenia by high-throughput in vivo phenotyping

scientific article published on October 2010

The pharmacogenomics of statins.

scientific article published on 21 December 2013

The pharmacokinetics of oxypurinol in people with gout

scientific article

The safety and tolerability of Annona muricata leaf extract: a systematic review

scientific article published on 28 October 2019

Therapeutic Drug Monitoring in Older People

Therapeutic drug monitoring of atazanavir: surveillance of pharmacotherapy in the clinic

scientific article published in September 2005

Timing of Administration: For Commonly-Prescribed Medicines in Australia

scientific article

Too much medicine in older people? Deprescribing through shared decision making

scientific article published on 3 June 2016

Trial of Pregabalin for Acute and Chronic Sciatica

scientific article

Understanding drug interactions with St John's wort (Hypericum perforatum L.): impact of hyperforin content

scientific article published on 7 February 2018

Understanding variability in posaconazole exposure using an integrated population pharmacokinetic analysis.

scientific article

Understanding variability with voriconazole using a population pharmacokinetic approach: implications for optimal dosing

scientific article published on 18 February 2014

Validation of a survey tool to assess the patient safety attitudes of pharmacy students.

scientific article published on 10 September 2015

Validation of methods to study the distribution and protein binding of tacrolimus in human blood

scientific article published in July 2001

Vancomycin pharmacokinetics in patients with severe burn injuries

scientific article published on 28 October 2009

Variability in response to medicines in older people: phenotypic and genotypic factors.

scientific article published on 18 February 2009

Vincristine chemotherapy trials and pharmacokinetics in tasmanian devils with tasmanian devil facial tumor disease.

scientific article

Voriconazole pharmacokinetics and exposure-response relationships: assessing the links between exposure, efficacy and toxicity

scientific article

Warfarin metabolites: Stereochemical aspects of protein binding and displacement by phenylbutazone

scientific article published on 01 January 1993

What proportion of patients with chronic noncancer pain are prescribed an opioid medicine? Systematic review and meta-regression of observational studies

scientific article published on 25 February 2020

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