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List of works by Isak S. Pretorius

A breeding strategy to harness flavor diversity of Saccharomyces interspecific hybrids and minimize hydrogen sulfide production

scientific article published on 10 April 2012

Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae

scientific article published on 04 November 2020

Applications of Yeast Synthetic Biology Geared towards the Production of Biopharmaceuticals

scientific article published on 06 July 2018

Assimilable nitrogen utilisation and production of volatile and non-volatile compounds in chemically defined medium by Saccharomyces cerevisiae wine yeasts.

scientific article published on 11 September 2007

At the cutting-edge of grape and wine biotechnology

scientific article published on 04 December 2012

Author Correction: Building a global alliance of biofoundries

scientific article published on 11 July 2019

Benchmarking two Saccharomyces cerevisiae laboratory strains for growth and transcriptional response to methanol

scientific article published on 16 October 2019

Bio-informational futures: The convergence of artificial intelligence and synthetic biology

scientific article published on 11 February 2020

Bioinformational trends in grape and wine biotechnology

scientific article published in January 2022

Building a global alliance of biofoundries

scientific article published on 09 May 2019

Characteristics of Flo11-dependent flocculation in Saccharomyces cerevisiae.

scientific article

Characterization of a novel alpha-amylase from Lipomyces kononenkoae and expression of its gene (LKA1) in Saccharomyces cerevisiae

scientific article published on 01 November 1995

Cloning and characterization of a second alpha-amylase gene (LKA2) from Lipomyces kononenkoae IGC4052B and its expression in Saccharomyces cerevisiae.

scientific article published on January 2003

Cloning and expression of an Aspergillus kawachii endo-1,4-beta-xylanase gene in Saccharomyces cerevisiae

scientific article published in October 1995

Cloning and expression of the alpha-L-arabinofuranosidase gene (ABF2) of Aspergillus niger in Saccharomyces cerevisiae

scientific article published in October 1996

Cloning, mapping and characterization of a genomic copy of the Lipomyces kononenkoae alpha-amylase-encoding gene (LKA1).

scientific article published on August 1996

Co-expression of a Phanerochaete chrysosporium cellobiohydrolase gene and a Butyrivibrio fibrisolvens endo-beta-1,4-glucanase gene in Saccharomyces cerevisiae

scientific article published in August 1996

Co-expression of a Saccharomyces diastaticus glucoamylase-encoding gene and a Bacillus amyloliquefaciens alpha-amylase-encoding gene in Saccharomyces cerevisiae

scientific article published in April 1991

Coinoculated fermentations using saccharomyces yeasts affect the volatile composition and sensory properties of Vitis vinifera L. cv. sauvignon blanc wines

scientific article

Comparative genome analysis of a Saccharomyces cerevisiae wine strain

scientific article published on 4 September 2008

Comparative genomics: a revolutionary tool for wine yeast strain development

scientific article published on September 1, 2012

Construction of a synthetic Saccharomyces cerevisiae pan-genome neo-chromosome

Construction of a synthetic Saccharomyces cerevisiae pan-genome neo-chromosome

scientific article published on 24 June 2022

Coregulation of Starch Degradation and Dimorphism in the Yeast Saccharomyces cerevisiae

scientific article published on January 1, 1997

Correlation between glucose/fructose discrepancy and hexokinase kinetic properties in different Saccharomyces cerevisiae wine yeast strains

scientific article published on 23 October 2007

De-novo assembly and analysis of the heterozygous triploid genome of the wine spoilage yeast Dekkera bruxellensis AWRI1499.

scientific article

Degradation of xylan to D-xylose by recombinant Saccharomyces cerevisiae coexpressing the Aspergillus niger beta-xylosidase (xlnD) and the Trichoderma reesei xylanase II (xyn2) genes.

scientific article

Discrepancy in glucose and fructose utilisation during fermentation by Saccharomyces cerevisiae wine yeast strains

scientific article published in May 2004

Drawing on the Past to Shape the Future of Synthetic Yeast Research

scientific article published on 28 September 2020

Effect of Isomixing on Grape Must Fermentations of ATF1-Overexpressing Wine Yeast Strains

scientific article published on 02 June 2020

Effect of the cellulose-binding domain on the catalytic activity of a beta-glucosidase from Saccharomycopsis fibuligera

scientific article published on 27 February 2007

Electron microscopy of the K2 killer effect of Saccharomyces cerevisiae T206 on a mesophilic wine yeast

scientific article

Engineering volatile thiol release in Saccharomyces cerevisiae for improved wine aroma

scientific article published in July 2007

Engineering yeast for efficient cellulose degradation

scientific article published on January 15, 1998

Enhancing volatile phenol concentrations in wine by expressing various phenolic acid decarboxylase genes in Saccharomyces cerevisiae.

scientific article published on August 2003

Establishing a risk-assessment process for release of genetically modified wine yeast into the environment

scientific article published on August 2009

Evaluation of gene modification strategies for the development of low-alcohol-wine yeasts.

scientific article published on 22 June 2012

Evolutionary engineering in reveals a -dependent potassium influx mechanism for propionic acid tolerance

Expression and secretion of Bacillus amyloliquefaciens alpha-amylase by using the yeast pheromone alpha-factor promoter and leader sequence in Saccharomyces cerevisiae.

scientific article

Expression levels of the yeast alcohol acetyltransferase genes ATF1, Lg-ATF1, and ATF2 control the formation of a broad range of volatile esters.

scientific article

Expression of human P450c17 as an export protein in Saccharomyces cerevisiae

scientific article

Expression of the Butyrivibrio fibrisolvens endo-beta-1,4-glucanase gene together with the Erwinia pectate lyase and polygalacturonase genes in Saccharomyces cerevisiae

scientific article published on 01 December 1994

Fermenting knowledge: the history of winemaking, science and yeast research.

scientific article

Festive foods

scientific article published on 10 November 2014

Flavor-Active Esters: Adding Fruitiness to Beer

scientific article published on 01 January 2003

Flavour-active wine yeasts

scientific article published on September 1, 2012

Functional analysis of multiple AUG codons in the transcripts of the STA2 glucoamylase gene from Saccharomyces cerevisiae

scientific article

Genetic and fermentation properties of the K2 killer yeast, Saccharomyces cerevisiae T206.

scientific article published in April 1998

Genetic determinants of volatile-thiol release by Saccharomyces cerevisiae during wine fermentation

scientific article published on September 2005

Genomic insights into the Saccharomyces sensu stricto complex

scientific article

Genomic insights into the evolution of industrial yeast species Brettanomyces bruxellensis

scientific article

Harnessing bioengineered microbes as a versatile platform for space nutrition

Harnessing bioengineered microbes as a versatile platform for space nutrition

scientific article published on 19 October 2022

Heterologous production of raspberry ketone in the wine yeast Saccharomyces cerevisiae via pathway engineering and synthetic enzyme fusion

scientific article published on 04 March 2016

Identification and physical characterization of yeast glucoamylase structural genes

scientific article published on 01 April 1986

Identification of a functional TATA element in the STA2 glucoamylase gene promoter from Saccharomyces cerevisiae

scientific article published in January 1998

Identification of lactic acid bacteria isolated from South African brandy base wines.

scientific article published in February 2004

Influence of wine fermentation temperature on the synthesis of yeast-derived volatile aroma compounds

scientific article published on 16 October 2007

Isolation of sulfite reductase variants of a commercial wine yeast with significantly reduced hydrogen sulfide production.

scientific article

MSS11, a novel yeast gene involved in the regulation of starch metabolism

scientific article published on October 1, 1997

Metabolic engineering of Saccharomyces cerevisiae for the synthesis of the wine-related antioxidant resveratrol

scientific article published in October 2003

Microbial Cellulose Utilization: Fundamentals and Biotechnology

scientific article published in 2002

Modulating aroma compounds during wine fermentation by manipulating carnitine acetyltransferases in Saccharomyces cerevisiae

scientific article published on 29 November 2006

Modulation of volatile sulfur compounds by wine yeast.

scientific article published on 30 January 2007

Molecular cloning and characterization of the STA2 glucoamylase gene of Saccharomyces diastaticus.

scientific article

Mss11p is a central element of the regulatory network that controls FLO11 expression and invasive growth in Saccharomyces cerevisiae.

scientific article

Mss11p is a transcription factor regulating pseudohyphal differentiation, invasive growth and starch metabolism in Saccharomyces cerevisiae in response to nutrient availability.

scientific article published on January 2003

Muc1, a mucin-like protein that is regulated by Mss10, is critical for pseudohyphal differentiation in yeast

scientific article

Multiple positive and negative cis-acting elements of the STA2 gene regulate glucoamylase synthesis in Saccharomyces cerevisiae

scientific article published in September 1994

Not your ordinary yeast: non-Saccharomyces yeasts in wine production uncovered.

scientific article

Novel wine yeast with mutations in YAP1 that produce less acetic acid during fermentation

scientific article published on 12 November 2012

One-step enzymatic hydrolysis of starch using a recombinant strain of Saccharomyces cerevisiae producing alpha-amylase, glucoamylase and pullulanase

scientific article published in March 1995

Over-expression of the Saccharomyces cerevisiae exo-beta-1,3-glucanase gene together with the Bacillus subtilis endo-beta-1,3-1,4-glucanase gene and the Butyrivibrio fibrisolvens endo-beta-1,4-glucanase gene in yeast

scientific article published in May 1997

Plasmids in Leuconostoc oenos

scientific article published on 01 March 1987

Population sequencing reveals clonal diversity and ancestral inbreeding in the grapevine cultivar Chardonnay

scientific article published on 20 November 2018

Preliminary evaluation of infrared spectroscopy for the differentiation of Brettanomyces bruxellensis strains isolated from red wines

scientific article published on 11 August 2010

Principal component analysis applied to Fourier transform infrared spectroscopy for the design of calibration sets for glycerol prediction models in wine and for the detection and classification of outlier samples

scientific article

Rapid Colorimetric Detection of Genome Evolution in SCRaMbLEd Synthetic <i>Saccharomyces cerevisiae</i> Strains

scientific article published on 01 December 2020

Rapid optimisation of cellulolytic enzymes ratios in Saccharomyces cerevisiae using in vitro SCRaMbLE

scientific article published on 03 November 2020

Rapid screening of the fermentation profiles of wine yeasts by Fourier transform infrared spectroscopy

scientific article published on 11 May 2006

Redesign of carnitine acetyltransferase specificity by protein engineering

scientific journal article

Regional sequence homologies in starch-degrading enzymes.

scientific article published in November 1993

Regulation of respiratory growth by Ras: the glyoxylate cycle mutant, cit2Δ, is suppressed by RAS2

scientific article published on 11 July 2006

Saccharomyces cerevisiae

scientific article published on 17 October 2019

Seeding the idea of encapsulating a representative synthetic metagenome in a single yeast cell

Seeding the idea of encapsulating a representative synthetic metagenome in a single yeast cell

scientific article published on 11 March 2021

Selection of yeast starter culture strains for the production of marula fruit wines and distillates

scientific article published in March 2002

Sensing the future of bio-informational engineering

scientific article published in 2021

Solving yeast jigsaw puzzles over a glass of wine: Synthetic genome engineering pioneers new possibilities for wine yeast research

scientific article published on 23 October 2017

Starch fermentation by recombinant saccharomyces cerevisiae strains expressing the alpha-amylase and glucoamylase genes from lipomyces kononenkoae and saccharomycopsis fibuligera

scientific article published in December 2003

Synthesis and secretion of an Erwinia chrysanthemi pectate lyase in Saccharomyces cerevisiae regulated by different combinations of bacterial and yeast promoter and signal sequences

scientific article published on 01 November 1992

Synthetic Evolution of Metabolic Productivity Using Biosensors

scientific article published on 3 March 2016

Synthetic biology stretching the realms of possibility in wine yeast research.

scientific article

Synthetic genome engineering forging new frontiers for wine yeast

scientific article published on 18 August 2016

Systems-based approaches enable identification of gene targets which improve the flavour profile of low-ethanol wine yeast strains

scientific article published on 20 August 2018

Tasting the terroir of wine yeast innovation

scientific article published on 01 February 2020

The S1, S2 and SGA1 ancestral genes for the STA glucoamylase genes all map to chromosome IX in Saccharomyces cerevisiae

scientific article published on 01 June 1995

The Saccharomyces cerevisiae alcohol acetyl transferase gene ATF1 is a target of the cAMP/PKA and FGM nutrient-signalling pathways

scientific article

The Saccharomyces cerevisiae chitinase, encoded by the CTS1-2 gene, confers antifungal activity against Botrytis cinerea to transgenic tobacco.

scientific article

The Sensory Significance of Apocarotenoids in Wine: Importance of Carotenoid Cleavage Dioxygenase 1 (CCD1) in the Production of β-Ionone

scientific article published on 16 June 2020

The Whiff of Wine Yeast Innovation: Strategies for Enhancing Aroma Production by Yeast during Wine Fermentation

scientific article published on 25 November 2019

The effect of increased branched-chain amino acid transaminase activity in yeast on the production of higher alcohols and on the flavour profiles of wine and distillates

article

The effect of increased yeast alcohol acetyltransferase and esterase activity on the flavour profiles of wine and distillates

scientific article published on 01 July 2006

The effect of polysaccharide-degrading wine yeast transformants on the efficiency of wine processing and wine flavour

scientific article published on 27 April 2006

The effect of sulphur dioxide and oxygen on the viability and culturability of a strain of Acetobacter pasteurianus and a strain of Brettanomyces bruxellensis isolated from wine

scientific article

The genome sequence of the wine yeast VIN7 reveals an allotriploid hybrid genome with Saccharomyces cerevisiae and Saccharomyces kudriavzevii origins

scientific article published on 23 December 2011

The grapevine polygalacturonase-inhibiting protein (VvPGIP1) reduces Botrytis cinerea susceptibility in transgenic tobacco and differentially inhibits fungal polygalacturonases

scientific article published on 27 October 2006

The heterologous expression of polysaccharidase-encoding genes with oenological relevance in Saccharomyces cerevisiae

scientific article published in December 2007

The sensing of nutritional status and the relationship to filamentous growth in Saccharomyces cerevisiae.

scientific article

The value of electrophoretic fingerprinting and karyotyping in wine yeast breeding programmes

scientific article published in May 1992

The winemaker's bug: From ancient wisdom to opening new vistas with frontier yeast science.

scientific article

Trimming the genomic fat: minimising and re-functionalising genomes using synthetic biology

scientific article published on 8 April 2023

Variation in 4-mercapto-4-methyl-pentan-2-one release by Saccharomyces cerevisiae commercial wine strains.

scientific article published in November 2004

Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of Saccharomyces cerevisiae

scientific article

Yeast 2.0-connecting the dots in the construction of the world's first functional synthetic eukaryotic genome.

scientific article published in June 2018

Yeast systems biology: modelling the winemaker's art.

scientific article published on 27 June 2007

Yeast's balancing act between ethanol and glycerol production in low-alcohol wines

scientific article published on 13 January 2017