List of works - Clelia Dallanoce

A chemoenzymatic approach to the synthesis of the stereoisomers of a β-adrenergic receptor antagonist

A convenient synthesis of 4-(2-hydroxyethyl)indolin-2-one, a useful intermediate for the preparation of both dopamine receptor agonists and protein kinase inhibitors

scholarly article by Carlo Matera et al published 17 April 2014 in Monatshefte für Chemie

A novel spirocyclic tropanyl-Δ²-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters as well as serotonin uptake

scientific article

Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study

scientific article published on 04 March 2020

Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells

scientific article published on 24 April 2018

Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor.

scientific article published on May 2013

Allosteric ligands for G protein-coupled receptors: a novel strategy with attractive therapeutic opportunities

scientific article published on May 2010

Back Cover: Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation (ChemMedChem 16/2017)

scholarly article by Marta Quadri et al published 22 August 2017 in ChemMedChem

Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

scientific article

Chemoenzymatic synthesis of the enantiomers of desoxymuscarine

Design of novel alpha7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies

scientific article published on 24 September 2009

Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors

scientific article published in January 2006

Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors

scientific article

Determination of acid dissociation constants of compounds active at neuronal nicotinic acetylcholine receptors by means of electrophoretic and potentiometric techniques

scientific article published in January 2010

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

scientific article published on 8 October 2008

Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor.

scientific article

Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors

scientific article published on 21 July 2011

Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes

scientific article published on 10 July 2008

Free-solution capillary electrophoretic resolution of chiral amino acids via derivatization with homochiral isothiocyanates. Part I

Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

scientific article

Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes

scientific article

Involvement of α7 nAChR subtype in rat oxaliplatin-induced neuropathy: effects of selective activation

scientific article

Lactam Enolate-Pyridone Addition: Synthesis of 4-Halocytisines

article

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

scientific article

New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations

scientific article published in February 2009

New analogues of oxotremorine and oxotremorine-M: estimation of their in vitro affinity and efficacy at muscarinic receptor subtypes.

scientific article published in June 2000

New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors

scientific article

Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation

scientific article published on 11 October 2018

Novel chiral isoxazole derivatives: synthesis and pharmacological characterization at human beta-adrenergic receptor subtypes

scientific article published on 2 February 2007

Novel oxotremorine-related heterocyclic derivatives: Synthesis and in vitro pharmacology at the muscarinic receptor subtypes

scientific article

Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes

scientific article published on 27 April 2010

On the selection of an opioid for local skin analgesia: Structure-skin permeability relationships

scientific article published on 28 April 2015

Pharmacological profile of enantiomerically pure chiral muscarinic agonists: desoxymuscarines

scientific article published in June 2000

Semisynthetic derivatives of purpuromycin as potential topical agents for vaginal infections

scientific article published in March 1997

Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system

scientific article published on 16 December 2011

Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine

scientific article published in 1997

Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M.

scientific article published in August 1999

Synthesis and pharmacological characterization of new chiral derivatives of muscarine and allo-muscarine.

scientific article published in August 2000

Synthesis and pharmacological investigation of stereoisomeric muscarines.

scientific article published in January 1992

Synthesis of Epibatidine-Related Δ2-Isoxazoline Derivatives and Evaluation of Their Binding Affinity at Neuronal Nicotinic Acetylcholine Receptors

Synthesis of enantiopure Delta2-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human beta-adrenergic receptor subtypes

scientific article published on 10 March 2006

Synthesis of new bicyclic analogues of glutamic acid

Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists

scientific article

Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes

scientific article published on 17 September 2010

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling

scientific article

The enantiomers of epiboxidine and of two related analogs: Synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors

List of works by Clelia Dallanoce

A chemoenzymatic approach to the synthesis of the stereoisomers of a β-adrenergic receptor antagonist

A convenient synthesis of 4-(2-hydroxyethyl)indolin-2-one, a useful intermediate for the preparation of both dopamine receptor agonists and protein kinase inhibitors

A novel spirocyclic tropanyl-Δ²-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters as well as serotonin uptake

Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study

Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells

Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor.

Allosteric ligands for G protein-coupled receptors: a novel strategy with attractive therapeutic opportunities

Back Cover: Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation (ChemMedChem 16/2017)

Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

Chemoenzymatic synthesis of the enantiomers of desoxymuscarine

Design of novel alpha7-subtype-preferring nicotinic acetylcholine receptor agonists: application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies

Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors

Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors

Determination of acid dissociation constants of compounds active at neuronal nicotinic acetylcholine receptors by means of electrophoretic and potentiometric techniques

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor.

Engineering of α-conotoxin MII-derived peptides with increased selectivity for native α6β2* nicotinic acetylcholine receptors

Epiboxidine and novel-related analogues: a convenient synthetic approach and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes

Free-solution capillary electrophoretic resolution of chiral amino acids via derivatization with homochiral isothiocyanates. Part I

Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes

Involvement of α7 nAChR subtype in rat oxaliplatin-induced neuropathy: effects of selective activation

Lactam Enolate-Pyridone Addition: Synthesis of 4-Halocytisines

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

New analogues of epiboxidine incorporating the 4,5-dihydroisoxazole nucleus: synthesis, binding affinity at neuronal nicotinic acetylcholine receptors, and molecular modeling investigations

New analogues of oxotremorine and oxotremorine-M: estimation of their in vitro affinity and efficacy at muscarinic receptor subtypes.

New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors

Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation

Novel chiral isoxazole derivatives: synthesis and pharmacological characterization at human beta-adrenergic receptor subtypes

Novel oxotremorine-related heterocyclic derivatives: Synthesis and in vitro pharmacology at the muscarinic receptor subtypes

Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes

On the selection of an opioid for local skin analgesia: Structure-skin permeability relationships

Pharmacological profile of enantiomerically pure chiral muscarinic agonists: desoxymuscarines

Semisynthetic derivatives of purpuromycin as potential topical agents for vaginal infections

Synthesis and binding affinity at α4β2 and α7 nicotinic acetylcholine receptors of new analogs of epibatidine and epiboxidine containing the 7-azabicyclo[2.2.1]hept-2-ene ring system

Synthesis and binding affinity of new muscarinic ligands structurally related to oxotremorine

Synthesis and functional characterization of novel derivatives related to oxotremorine and oxotremorine-M.

Synthesis and pharmacological characterization of new chiral derivatives of muscarine and allo-muscarine.

Synthesis and pharmacological investigation of stereoisomeric muscarines.

Synthesis of Epibatidine-Related Δ2-Isoxazoline Derivatives and Evaluation of Their Binding Affinity at Neuronal Nicotinic Acetylcholine Receptors

Synthesis of enantiopure Delta2-isoxazoline derivatives and evaluation of their affinity and efficacy profiles at human beta-adrenergic receptor subtypes

Synthesis of new bicyclic analogues of glutamic acid

Synthesis of new delta 2-isoxazoline derivatives and their pharmacological characterization as beta-adrenergic receptor antagonists

Synthesis of novel chiral Δ2-isoxazoline derivatives related to ABT-418 and estimation of their affinity at neuronal nicotinic acetylcholine receptor subtypes

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling

The enantiomers of epiboxidine and of two related analogs: Synthesis and estimation of their binding affinity at α4β2 and α7 neuronal nicotinic acetylcholine receptors