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List of works by Sin-Hyeog Im

6-Methoxyflavone inhibits NFAT translocation into the nucleus and suppresses T cell activation.

scientific article published on 11 August 2014

A distal cis-regulatory element, CNS-9, controls NFAT1 and IRF4-mediated IL-10 gene activation in T helper cells

scientific article

A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.

scientific article published in January 2005

A monoclonal antibody specific for rat IL-18BP and its application in determining serum IL-18BP

scientific article published on 01 January 2003

A novel splicing variant of mouse interleukin (IL)-24 antagonizes IL-24-induced apoptosis

scientific journal article

A triazine compound S06 inhibits proinvasive crosstalk between carcinoma cells and stromal fibroblasts via binding to heat shock protein 90.

scientific article

Abalone visceral extract inhibit tumor growth and metastasis by modulating Cox-2 levels and CD8+ T cell activity.

scientific article

Activation and deactivation of gene expression by Ca2+/calcineurin-NFAT-mediated signaling.

scientific article published in August 2004

Amelioration of Autoimmune Diabetes of NOD Mice by Immunomodulating Probiotics

scientific article published on 03 September 2020

Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response

article

Bcl11b prevents catastrophic autoimmunity by controlling multiple aspects of a regulatory T cell gene expression program

scientific article published on 07 August 2019

Bifidobacterium bifidum presents on the cell surface a complex mixture of glucans and galactans with different immunological properties

scientific article published on 03 May 2019

Bone marrow CX3CR1+ mononuclear cells relay a systemic microbiota signal to control hematopoietic progenitors in mice

scientific article published on 01 October 2019

Breakage of tolerance to hidden cytoplasmic epitopes of the acetylcholine receptor in experimental autoimmune myasthenia gravis

scientific article

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

scientific article

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.

scientific article published on 12 July 2017

Cell surface polysaccharides of induce the generation of Foxp3 regulatory T cells

scientific article published on 01 October 2018

Chromatin-level regulation of the IL10 gene in T cells.

scientific article

Cinnamon extract induces tumor cell death through inhibition of NFkappaB and AP1

scientific article

Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells

scientific article

Cinnamon extract suppresses tumor progression by modulating angiogenesis and the effector function of CD8+ T cells.

scientific article

Cisplatin induces tolerogenic dendritic cells in response to TLR agonists via the abundant production of IL-10, thereby promoting Th2- and Tr1-biased T-cell immunity.

scientific article published on 09 May 2016

Clinical Effect of IRT-5 Probiotics on Immune Modulation of Autoimmunity or Alloimmunity in the Eye.

scientific article published on 25 October 2017

Correction to: Cinnamon extract induces tumor cell death through inhibition of NFκB and AP1

scientific article published on 14 November 2019

Corrigendum: Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged mice

scientific article published on 31 January 2017

DA-9601 suppresses 2, 4-dinitrochlorobenzene and dust mite extract-induced atopic dermatitis-like skin lesions

scientific article published on 19 April 2011

Defect in TCR-CD3ζ signaling mediates T cell hypo-responsiveness in mesenteric lymph node

scientific article published on 11 July 2008

Dietary Glucose Consumption Promotes RALDH Activity in Small Intestinal CD103+CD11b+ Dendritic Cells

scientific article published on 11 August 2020

Differential Regulation of the IL-10 Gene in Th1 and Th2 T Cells

article

ETS1 Suppresses Tumorigenesis of Human Breast Cancer via Trans-Activation of Canonical Tumor Suppressor Genes

scientific article published on 14 May 2020

Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model

scientific article published on 01 December 2020

Enhanced chromatin accessibility and recruitment of JUNB mediate the sustained IL-4 expression in NFAT1 deficient T helper 2 cells

scientific article

Epigenetic regulation of cytokine gene expression in T lymphocytes

scientific article published on 23 June 2009

Epitope spreading to hidden cytoplasmic regions of the acetylcholine receptor in experimental autoimmune myasthenia gravis

scientific article published in September 2003

Erratum: Immune Disorders and Its Correlation with Gut Microbiome

scholarly article published in Immune Network

Essential Role for Signal Transducer and Activator of Transcription-1 in Pancreatic -Cell Death and Autoimmune Type 1 Diabetes of Nonobese Diabetic Mice

scientific article published on 09 July 2007

Ets1 suppresses atopic dermatitis by suppressing pathogenic T cell responses

article

Experimental autoimmune myasthenia gravis in mice expressing human immunoglobulin loci

scientific article

Expression and relationship of male reproductive ADAMs in mouse

scientific article

Extracellular vesicle-derived protein from Bifidobacterium longum alleviates food allergy through mast cell suppression

scientific article published on 30 September 2015

Flagellin suppresses experimental asthma by generating regulatory dendritic cells and T cells.

scientific article published on 21 August 2015

Foxp3 induces IL-4 gene silencing by affecting nuclear translocation of NFkappaB and chromatin structure

scientific article

Foxp3 is a novel repressor of microglia activation

scientific article published on August 2010

Generation of regulatory dendritic cells and CD4+Foxp3+ T cells by probiotics administration suppresses immune disorders

scientific article

Gut-Specific Delivery of T-Helper 17 Cells Reduces Obesity and Insulin Resistance in Mice.

scientific article published on 25 February 2017

HIF-1α activation in myeloid cells accelerates dextran sodium sulfate-induced colitis progression in mice

scientific article published on 30 July 2018

Handheld mechanical cell lysis chip with ultra-sharp silicon nano-blade arrays for rapid intracellular protein extraction

scientific article published on 16 March 2010

Harnessing the bioresponsive adhesion of immuno-bioglue for enhanced local immune checkpoint blockade therapy

scientific article published on 11 September 2020

House Dust Mite Increases pro-Th2 Cytokines, IL-25 and IL-33 via the Activation of TLR1/6 Signaling

scientific article published on 03 July 2017

Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis.

scientific article

IGSF4 is a novel TCR ζ-chain-interacting protein that enhances TCR-mediated signaling.

scientific article published on 14 November 2011

IL4 Receptor-Targeted Proapoptotic Peptide Blocks Tumor Growth and Metastasis by Enhancing Antitumor Immunity

scientific article published on 6 September 2017

IRF4 regulates IL-10 gene expression in CD4(+) T cells through differential nuclear translocation

scientific article published on 4 March 2011

IRT5 Probiotics Changes Immune Modulatory Protein Expression in the Extraorbital Lacrimal Glands of an Autoimmune Dry Eye Mouse Model

scientific article published on 01 March 2020

Imageable Antigen-Presenting Gold Nanoparticle Vaccines for Effective Cancer Immunotherapy In Vivo

Imageable antigen-presenting gold nanoparticle vaccines for effective cancer immunotherapy in vivo

scientific article published on 29 July 2012

Immune disorders and its correlation with gut microbiome

scientific article

Immunomodulatory effect of water soluble extract separated from mycelium of Phellinus linteus on experimental atopic dermatitis.

scientific article

Immunosuppression of rat myasthenia gravis by oral administration of a syngeneic acetylcholine receptor fragment

scientific article

Immunotherapy of myasthenia gravis

Inflammation-induced Id2 promotes plasticity in regulatory T cells

scientific article published in Nature Communications

Integrin-linked kinase is required in hypoxic mesenchymal stem cells for strengthening cell adhesion to ischemic myocardium

scientific article

Interaction of Ets-1 with HDAC1 represses IL-10 expression in Th1 cells.

scientific article published on 20 January 2012

Interleukin and interleukin receptor diversity: role of alternative splicing

scientific article published on January 2010

Intestinal microbiota controls acute kidney injury severity by immune modulation

scientific article published on 26 May 2020

JunB and c-Rel cooperatively enhance Foxp3 expression during induced regulatory T cell differentiation.

scientific article published in March 2011

Lactobacillus casei enhances type II collagen/glucosamine-mediated suppression of inflammatory responses in experimental osteoarthritis.

scientific article

Lactobacillus casei potentiates induction of oral tolerance in experimental arthritis.

scientific article published on 19 September 2008

Lactobacillus casei suppresses experimental arthritis by down-regulating T helper 1 effector functions

scientific article published on 19 February 2008

Lactobacillus helveticus suppresses experimental rheumatoid arthritis by reducing inflammatory T cell responses

article

Lactobacillus pentosus KF340 alleviates house dust mite-induced murine atopic dermatitis via the secretion of IL-10-producing splenic B10 cells

article by Min-Jung Bae et al published October 2016 in Journal of Functional Foods

Lactobacillus pentosus Modulates Immune Response by Inducing IL-10 Producing Tr1 Cells

scientific article published on 26 December 2019

Lef1 regulates COX-2 transcription in chondrocytes

scientific article published on 11 October 2007

Locus-Specific Reversible DNA Methylation Regulates Transient IL-10 Expression in Th1 Cells

scientific article published on 26 January 2018

Looping mediated interaction between the promoter and 3' UTR regulates type II collagen expression in chondrocytes

scientific article

Lymphoid Enhancer Binding Factor 1 Regulates Transcription through Gene Looping

article

Mechanism of nasal tolerance induced by a recombinant fragment of acetylcholine receptor for treatment of experimental myasthenia gravis

scientific article published on 01 November 2000

Modulation of experimental atopic dermatitis by topical application of Gami-Cheongyeul-Sodok-Eum.

scientific article

Modulation of gut microbiota and delayed immunosenescence as a result of syringaresinol consumption in middle-aged mice ⬇️

scientific article published on 15 December 2016

Molecular Mechanisms Governing IL-24 Gene Expression.

scientific article published on 29 February 2012

NAMPT suppresses glucose deprivation-induced oxidative stress by increasing NADPH levels in breast cancer

scientific article published on 16 November 2015

NF-kappaB regulates Lef1 gene expression in chondrocytes

scientific article published on 5 April 2007

NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property.

scientific article published on 29 September 2017

NFAT1 and JunB cooperatively regulate IL-31 gene expression in CD4+ T cells in health and disease.

scientific article

Nuclear Speckle-related Protein 70 Binds to Serine/Arginine-rich Splicing Factors 1 and 2 via an Arginine/Serine-like Region and Counteracts Their Alternative Splicing Activity

scientific article published on 21 January 2016

Nuclear factor of activated T cells 1 (NFAT1)-induced permissive chromatin modification facilitates nuclear factor-κB (NF-κB)-mediated interleukin-9 (IL-9) transactivation

scientific article

Of men in mice: the development and application of a humanized gnotobiotic mouse model for microbiome therapeutics

scientific article published on 10 September 2020

Probiotics as a Potential Immunomodulating Pharmabiotics in Allergic Diseases: Current Status and Future Prospects

scientific article published on 01 November 2018

Probiotics as an Immune Modulator for Allergic Disorders

Probiotics as an Immune Modulator.

scientific article published in January 2015

Prophylactic effect of probiotics on the development of experimental autoimmune myasthenia gravis

scientific article

Protective molecular mimicry in experimental myasthenia gravis

scientific article published in May 2002

Rat interleukin-18 binding protein: cloning, expression, and characterization

scientific journal article

Role of Blimp-1 in programing Th effector cells into IL-10 producers

scientific article published on 29 July 2014

Salmonella typhimurium Suppresses Tumor Growth via the Pro-Inflammatory Cytokine Interleukin-1β.

scientific article

Small molecules that recapitulate the early steps of urodele amphibian limb regeneration and confer multipotency.

scientific article

Special issue on the human microbiome: from symbiosis to therapy

scientific article published on 10 September 2020

Spontaneous Proliferation of CD4 T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8 T Cells

Stat6 and c-Jun mediate Th2 cell-specific IL-24 gene expression.

scientific article published on 25 February 2011

Structural analysis of immunotherapeutic peptides for autoimmune Myasthenia gravis

scientific article

Structural features and immunological perception of the cell surface glycans of Lactobacillus plantarum: a novel rhamnose-rich polysaccharide and teichoic acids

scientific article published on 10 January 2020

Suppression of experimental myasthenia gravis by a B-cell epitope-free recombinant acetylcholine receptor

scientific article

Suppression of experimental myasthenia gravis, a B cell-mediated autoimmune disease, by blockade of IL-18.

scientific article published in October 2001

Suppression of myasthenia gravis by antigen-specific mucosal tolerance and modulation of cytokines and costimulatory factors

scientific article published in September 2003

Suppression of ongoing experimental myasthenia by oral treatment with an acetylcholine receptor recombinant fragment.

scientific article

Swiprosin-1 is expressed in mast cells and up-regulated through the protein kinase C beta I/eta pathway

scientific article

T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells

scientific article published in Nature Communications

T-cell anergy

scientific article published on April 2004

TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse.

scientific article

TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity

scientific article published on 04 November 2019

Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction.

scientific article published in November 2017

Targeted chemoimmunotherapy using drug-loaded aptamer-dendrimer bioconjugates

scientific article published on 27 May 2011

The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus

scientific article published on 01 December 2018

The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus

scientific article published on 01 January 2019

The kinase PDK1 is essential for B-cell receptor mediated survival signaling.

scientific article

The probiotic mixture IRT5 ameliorates age-dependent colitis in rats

scientific article published on 20 April 2015

The transcription factor Foxp1 preserves integrity of an active Foxp3 locus in extrathymic Treg cells

scientific article published in Nature Communications

Topical application of Taglisodog-eum inhibits the development of experimental atopic dermatitis

scientific article published on 02 December 2012

Topical application of porcine placenta extract inhibits the progression of experimental contact hypersensitivity.

scientific article published on 30 October 2010

Transcription factor NFAT1 controls allergic contact hypersensitivity through regulation of activation induced cell death program.

scientific article published on 18 January 2016

Transcriptional mechanisms underlying lymphocyte tolerance.

scientific article

Transcriptional regulation of IL-8 by iron chelator in human epithelial cells is independent from NF-kappaB but involves ERK1/2- and p38 kinase-dependent activation of AP-1.

scientific article published in December 2007

Transcriptional regulation of MMP13 by Lef1 in chondrocytes

scientific article published on 29 October 2007

Two-photon microscopy of Paneth cells in the small intestine of live mice

scientific article published in Scientific Reports

Upregulation of Ets1 expression by NFATc2 and NFKB1/RELA promotes breast cancer cell invasiveness

scientific article published on 23 November 2018

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