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List of works by Lai K. Leung

2,3,7,8-Tetrachlorodibenzo-para-dioxin increases aromatase (CYP19) mRNA stability in MCF-7 cells.

scientific article

A metaphyseal fracture rat model for mechanistic studies of osteoporotic bone healing

scientific article published on 22 May 2019

A positive feedback pathway of estrogen biosynthesis in breast cancer cells is contained by resveratrol

scientific article

A potential protective mechanism of soya isoflavones against 7,12-dimethylbenz[a]anthracene tumour initiation

scientific article published in August 2003

A systematic review of current osteoporotic metaphyseal fracture animal models

scientific article published in January 2018

Activation of hepatic NF-kappaB by phenobarbital in rats

scientific article published on 01 December 1996

Aflatoxin B1 augments the synthesis of corticotropin releasing hormone in JEG-3 placental cells.

scientific article published on 28 May 2015

Aflatoxin B1 disrupts transient receptor potential channel activity and increases COX-2 expression in JEG-3 placental cells

scientific article published on 3 November 2016

Age-related differences in volumetric bone mineral density, microarchitecture, and bone strength of distal radius and tibia in Chinese women: a high-resolution pQCT reference database study.

scientific article published on 28 January 2015

Apigenin and luteolin display differential hypocholesterolemic mechanisms in mice fed a high-fat diet

scientific article

Assessing placental corticotrophin-releasing hormone disruption by hexestrol in a cell model

scientific article published on 12 October 2016

Assessing the effect of food mycotoxins on aromatase by using a cell-based system.

scientific article published on 7 February 2014

Baicalein and genistein display differential actions on estrogen receptor (ER) transactivation and apoptosis in MCF-7 cells

scientific article published in December 2002

Baicalein inhibits DMBA-DNA adduct formation by modulating CYP1A1 and CYP1B1 activities

scientific article published in August 2002

Bisphenol A differentially activates protein kinase C isoforms in murine placental tissue

scientific article published on 29 March 2013

Bisphenol A downregulates CYP19 transcription in JEG-3 cells.

scientific article

Celecoxib increases miR-222 while deterring aromatase-expressing breast tumor growth in mice

scientific article

Co-administrating apigenin in a high-cholesterol diet prevents hypercholesterolaemia in golden hamsters

scientific article published on 25 June 2018

Coadministrating luteolin minimizes the side effects of the aromatase inhibitor letrozole.

scientific article published on 19 August 2014

Dietary administration of the licorice flavonoid isoliquiritigenin deters the growth of MCF-7 cells overexpressing aromatase.

scientific article

Dietary flavones counteract phorbol 12-myristate 13-acetate-induced SREBP-2 processing in hepatic cells

scientific article published on 24 October 2016

Differential effect of over-expressing UGT1A1 and CYP1A1 on xenobiotic assault in MCF-7 cells

scientific article published on 29 September 2007

Differential effects of chemotherapeutic agents on the Bcl-2/Bax apoptosis pathway in human breast cancer cell line MCF-7.

scientific article published on May 1999

Effect of dietary flavonols on oestrogen receptor transactivation and cell death induction

scientific article published on June 2004

Effect of dioxin exposure on aromatase expression in ovariectomized rats

scientific article

Effect of the peroxisome proliferator ciprofibrate on hepatic cyclooxygenase and phospholipase A2 in rats

scientific article published on 01 February 1998

Effect of zeranol on expression of apoptotic and cell cycle proteins in murine placentae

scientific article published on 8 October 2013

Exposure to 2,2',4,4'-tetrabromodiphenyl ether at late gestation modulates placental signaling molecules in the mouse model

scientific article published on 22 April 2017

Exposure to aflatoxin B1 in late gestation alters protein kinase C and apoptotic protein expression in murine placenta

scientific article published on 8 March 2016

Genistein and daidzein induced apoA-1 transactivation in hepG2 cells expressing oestrogen receptor-alpha

scientific article published on 16 November 2007

Genistein upregulates placental corticotropin-releasing hormone expression in lipopolysaccharide-sensitized mice

scientific article published on 4 August 2011

Genistein-induced apoptosis in MCF-7 cells involves changes in Bak and Bcl-x without evidence of anti-oestrogenic effects

scientific article published on November 2002

Hydroxychalcones exhibit differential effects on XRE transactivation.

scientific article

Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells

scientific article published on 27 June 2019

Lack of correlation between hepatic prostaglandin concentrations and DNA synthesis after the administration of phenobarbital and the peroxisome proliferator ciprofibrate in rats

scientific article published on 01 November 1997

Low magnitude high frequency vibration accelerated cartilage degeneration but improved epiphyseal bone formation in anterior cruciate ligament transect induced osteoarthritis rat model.

scientific article published on 20 May 2014

Low-magnitude high-frequency vibration enhanced mesenchymal stem cell recruitment in osteoporotic fracture healing through the SDF-1/CXCR4 pathway.

scientific article published on 24 May 2016

Mechanical stimulation enhanced estrogen receptor expression and callus formation in diaphyseal long bone fracture healing in ovariectomy-induced osteoporotic rats

scientific article published on 7 May 2016

Methylation dictates PI.f-specific CYP19 transcription in human glial cells

scientific article

Oestrogen receptor alpha is required for biochanin A-induced apolipoprotein A-1 mRNA expression in HepG2 cells

scientific article published on 29 May 2007

Oxidative stability of conjugated linoleic acid isomers

scientific article published on 01 August 2000

PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells

scientific article published on 03 July 2018

Pharmacological concentration of resveratrol suppresses aromatase in JEG-3 cells

scientific article published on 2 August 2007

Phorbol 12-myristate 13-acetate promotes nuclear translocation of hepatic steroid response element binding protein-2.

scientific article

Reduction of the concentrations of prostaglandins E2 and F2alpha, and thromboxane B2 in cultured rat hepatocytes treated with the peroxisome proliferator ciprofibrate.

scientific article published in June 1996

Regulation of death promoter Bak expression by cell density and 17 beta-estradiol in MCF-7 cells

scientific article

Resistive vibration exercise retards bone loss in weight-bearing skeletons during 60 days bed rest.

scientific article published on 9 December 2011

Role of eicosanoid metabolism in carcinogenesis by peroxisome proliferators

scientific article published on 01 December 1996

Soy leaf lowers the ratio of non-HDL to HDL cholesterol in hamsters

scientific article

Soya isoflavones suppress phorbol 12-myristate 13-acetate-induced COX-2 expression in MCF-7 cells

scientific article published on July 2006

The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells

scientific article published on 24 August 2015

The activity of transient receptor potential channel C-6 modulates the differentiation of fat cells

scientific article published on 20 February 2019

The citrus flavonone hesperetin attenuates the nuclear translocation of aryl hydrocarbon receptor

scientific article published on 22 May 2018

The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice.

scientific article

The dietary flavonoid apigenin blocks phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in breast cell lines.

scientific article published on 4 August 2010

The effect of whole body vibration on fracture healing - a systematic review.

scientific article published on 7 September 2017

The flame retardant 2,2',4,4'-Tetrabromodiphenyl ether enhances the expression of corticotropin-releasing hormone in the placental cell model JEG-3.

scientific article published on 31 January 2017

The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68.

scientific article published on 15 May 2015

The licorice flavonoid isoliquiritigenin reduces DNA-binding activity of AhR in MCF-7 cells

scientific article published on 7 August 2014

The licorice flavonoid isoliquiritigenin suppresses phorbol ester-induced cyclooxygenase-2 expression in the non-tumorigenic MCF-10A breast cell line.

scientific article published on 23 December 2009

The neuroprotective effects of ipriflavone against H ₂O ₂ and amyloid beta induced toxicity in human neuroblastoma SH-SY5Y cells

scientific article published on 29 September 2013

The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase

scientific article

The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression ⬇️

scientific article published on 29 August 2007

The red clover (Trifolium pratense) isoflavone biochanin A modulates the biotransformation pathways of 7,12-dimethylbenz[a]anthracene

scientific article published in July 2003

The relationship between sarcopenia and fragility fracture-a systematic review

scientific article published on 04 January 2019

Treatment of rats with the peroxisome proliferator ciprofibrate results in increased liver NF-kappaB activity

scientific article published on 01 November 1996

Vibration treatment modulates macrophage polarisation and enhances early inflammatory response in oestrogen-deficient osteoporotic-fracture healing

scientific article published on 07 November 2019

Zeranol induces COX-2 expression through TRPC-3 activation in the placental cells JEG-3.

scientific article published on 17 May 2016

Zeranol upregulates corticotropin releasing hormone expression in the placental cell line JEG-3.

scientific article published on 26 March 2013

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