List of works - Sylvie Rabot

1H nuclear magnetic resonance spectroscopy-based studies of the metabolism of food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline by human intestinal microbiota.

scientific article

5-hydroxyoxindole, an indole metabolite, is present at high concentrations in brain

scientific article published in 2007

A new type of bacterial sulfatase reveals a novel maturation pathway in prokaryotes

scientific article

A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors

scientific article published on December 2005

Ability of Lactobacillus fermentum to overcome host alpha-galactosidase deficiency, as evidenced by reduction of hydrogen excretion in rats consuming soya alpha-galacto-oligosaccharides

scientific article

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats.

scientific article

Allergenic and immunogenic potential of cow's milk β-lactoglobulin and caseins evidenced without adjuvant in germ-free mice

scientific article published on 30 August 2011

Allergic Sensitization to Bovine β-Lactoglobulin: Comparison between Germ-Free and Conventional BALB/c Mice

scientific article published in 2009

Alterations of the hepatic xenobiotic-metabolizing enzymes by a glucosinolate-rich diet in germ-free rats: influence of a pre-induction with phenobarbital

scientific article published in July 1993

Anaerobic Sulfatase-Maturating Enzymes: Radical SAM Enzymes Able To Catalyze in Vitro Sulfatase Post-translational Modification

scientific article published in March 2007

Apple proanthocyanidins do not reduce the induction of preneoplastic lesions in the colon of rats associated with human microbiota

scientific article published in April 2010

Arabinoxylans and inulin differentially modulate the mucosal and luminal gut microbiota and mucin-degradation in humanized rats

scientific article published on 30 August 2011

Association of germ-free mice with a simplified human intestinal microbiota results in a shortened intestine.

scientific article

Axe intestin-cerveau : comment le microbiote intestinal influence la réponse au stress

scientific article published in 2015

BamHI restriction endonuclease analysis of Yersinia ruckeri plasmids and their relatedness to the genus Yersinia 42- to 47-megadalton plasmid

scientific article

Beta-glucuronidase in human intestinal microbiota is necessary for the colonic genotoxicity of the food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in rats.

scientific article published on 28 July 2007

Brussels sprouts, inulin and fermented milk alter the faecal microbiota of human microbiota-associated rats as shown by PCR-temporal temperature gradient gel electrophoresis using universal, Lactobacillus and Bifidobacterium 16S rRNA gene primers

scientific article published in May 2005

CCL20 Displays Antimicrobial Activity Against Cryptosporidium parvum, but Its Expression Is Reduced During Infection in the Intestine of Neonatal Mice.

scientific article published on 2 April 2015

Characterization of Cecal Microbiota and Response to an Orally Administered Lactobacillus Probiotic Strain in the Broiler Chicken

scientific article published on 24 October 2007

Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen

scientific article published in February 2003

Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions

scientific article

Commensal microbiota influence systemic autoimmune responses.

scientific article

Constitutive delivery of bovine beta-lactoglobulin to the digestive tracts of gnotobiotic mice by engineered Lactobacillus casei

scientific article

Consumption of Camembert cheese stimulates commensal enterococci in healthy human intestinal microbiota.

scientific article published in November 2007

Delayed bacterial colonization of the gut alters the host immune response to oral sensitization against cow's milk proteins

scientific article published on 12 October 2012

Development of test systems for the detection of compounds that prevent the genotoxic effects of heterocyclic aromatic amines: preliminary results with constituents of cruciferous vegetables and other dietary constituents.

scientific article published in January 1999

Dietary induction of phase II enzymes: a promising strategy for protection against DNA-reactive intermediates in man?

scientific article

Effect of common Brassica vegetables (Brussels sprouts and red cabbage) on the development of preneoplastic lesions induced by 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in liver and colon of Fischer 344 rats

scientific article published in March 2004

Effects of chair-restraint on gastrointestinal transit time and colonic fermentation in male rhesus monkey (Macaca mulatta).

scientific article published on August 1997

Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.

scientific article

Effects of the bacterial status of rats on the changes in some liver cytochrome P450 (EC 1.14.14.1) apoproteins consequent to a glucosinolate-rich diet

scientific article published in September 1998

Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine

scientific article

First evidences for a third sulfatase maturation system in prokaryotes from E. coli aslB and ydeM deletion mutants.

scientific article published on 7 February 2007

Formation of allyl isothiocyanate from sinigrin in the digestive tract of rats monoassociated with a human colonic strain of Bacteroides thetaiotaomicron

scientific article published in April 2001

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism.

scientific article published on 19 August 2010

Glucosinolates and glucosinolate derivatives: implications for protection against chemical carcinogenesis.

scientific article published in January 1994

Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system

scientific article published in January 1990

Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research

scientific article

Guidance for substantiating the evidence for beneficial effects of probiotics: impact of probiotics on digestive system metabolism

scientific article

Gut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults

scientific article published on 31 July 2015

High fat diet drives obesity regardless the composition of gut microbiota in mice

scientific article

Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations

scientific article

Impact of bacteria in dairy products and of the intestinal microflora on the genotoxic and carcinogenic effects of heterocyclic aromatic amines

scientific article

Increased induction of apoptosis by Propionibacterium freudenreichii TL133 in colonic mucosal crypts of human microbiota-associated rats treated with 1,2-dimethylhydrazine

scientific article

Influence of cooking duration of cabbage and presence of colonic microbiota on the excretion of N-acetylcysteine conjugates of allyl isothiocyanate and bioactivity of phase 2 enzymes in F344 rats.

scientific article published on 29 October 2007

Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats

scientific article published in August 2003

Interactions between the intestinal flora and xenobiotic metabolizing enzymes and their health consequences.

scientific article

Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice

scientific article (publication date: 2013)

Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease.

scientific article published on 7 December 2015

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice.

scientific article

Intestinal microflora plays a crucial role in the genotoxicity of the cooked food mutagen 2-amino-3-methylimidazo [4,5-f]quinoline

scientific article

Metabolic fate of ochratoxin A as a coffee contaminant in a dynamic simulator of the human colon.

scientific article

Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model.

scientific article

Microbial community development in a dynamic gut model is reproducible, colon region specific, and selective for Bacteroidetes and Clostridium cluster IX

scientific article

Microbial metabolites control the thymic development of mucosal-associated invariant T cells

scientific article published on 29 August 2019

Modulation of the biological effects of glucosinolates by inulin and oat fibre in gnotobiotic rats inoculated with a human whole faecal flora

scientific article published in August 1996

Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation.

scientific article published on 12 October 2015

Neonatal mono-colonization of germ-free mice with Lactobacillus casei enhances casein immunogenicity after oral sensitization to cow's milk.

scientific article

Olfactory epithelium changes in germfree mice

scientific article published on 19 April 2016

Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids

scientific article published in November 2000

Proanthocyanidins and human health: systemic effects and local effects in the gut.

scientific article

Protective effects of Brussels sprouts, oligosaccharides and fermented milk towards 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced genotoxicity in the human flora associated F344 rat: role of xenobiotic metabolising enzymes and intestinal micr

scientific article published in March 2004

Rape-seed meal toxicity in gnotobiotic rats: influence of a whole human faecal flora or single human strains of Escherichia coli and Bacteroides vulgatus.

scientific article

Role of the Gut Microbiota in the Pathophysiology of Autism Spectrum Disorder: Clinical and Preclinical Evidence

scientific article published on 07 September 2020

Semi-automated solid-phase extraction method for studying the biodegradation of ochratoxin A by human intestinal microbiota

scientific article published in April 2012

Short-chain fatty acids and polyamines in the pathogenesis of necrotizing enterocolitis: Kinetics aspects in gnotobiotic quails

scientific article published on 20 February 2009

Short-chain fructo-oligosaccharides modulate intestinal microbiota and metabolic parameters of humanized gnotobiotic diet induced obesity mice

scientific article

Survival and metabolic activity of selected strains of Propionibacterium freudenreichii in the gastrointestinal tract of human microbiota-associated rats

scientific article published in April 2007

Survival of Bifidobacterium animalis DN-173 010 in the Faecal Microbiota after Administration in Lyophilised Form or in Fermented Product – A Randomised Study in Healthy Adults

scientific article published on 24 October 2007

The activities of several detoxication enzymes are differentially induced by juices of garden cress, water cress and mustard in human HepG2 cells.

scientific article

The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine

scientific article

Tigloyl-CoA:pseudotropine acyl transferase—An enzyme of tropane alkaloid biosynthesis

Validation of fluorescent in situ hybridization combined with flow cytometry for assessing interindividual variation in the composition of human fecal microflora during long-term storage of samples

scientific article published in November 2004

Variations in digestive physiology of rats after short duration flights aboard the US space shuttle

scientific article published in 2000

Wine constituents inhibit thrombosis but not atherogenesis in C57BL/6 apolipoprotein E-deficient mice

scientific article published in August 2006

List of works by Sylvie Rabot

1H nuclear magnetic resonance spectroscopy-based studies of the metabolism of food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline by human intestinal microbiota.

5-hydroxyoxindole, an indole metabolite, is present at high concentrations in brain

A new type of bacterial sulfatase reveals a novel maturation pathway in prokaryotes

A novel mucosal vaccine based on live Lactococci expressing E7 antigen and IL-12 induces systemic and mucosal immune responses and protects mice against human papillomavirus type 16-induced tumors

Ability of Lactobacillus fermentum to overcome host alpha-galactosidase deficiency, as evidenced by reduction of hydrogen excretion in rats consuming soya alpha-galacto-oligosaccharides

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats.

Allergenic and immunogenic potential of cow's milk β-lactoglobulin and caseins evidenced without adjuvant in germ-free mice

Allergic Sensitization to Bovine β-Lactoglobulin: Comparison between Germ-Free and Conventional BALB/c Mice

Alterations of the hepatic xenobiotic-metabolizing enzymes by a glucosinolate-rich diet in germ-free rats: influence of a pre-induction with phenobarbital

Anaerobic Sulfatase-Maturating Enzymes: Radical SAM Enzymes Able To Catalyze in Vitro Sulfatase Post-translational Modification

Apple proanthocyanidins do not reduce the induction of preneoplastic lesions in the colon of rats associated with human microbiota

Arabinoxylans and inulin differentially modulate the mucosal and luminal gut microbiota and mucin-degradation in humanized rats

Association of germ-free mice with a simplified human intestinal microbiota results in a shortened intestine.

Axe intestin-cerveau : comment le microbiote intestinal influence la réponse au stress

BamHI restriction endonuclease analysis of Yersinia ruckeri plasmids and their relatedness to the genus Yersinia 42- to 47-megadalton plasmid

Beta-glucuronidase in human intestinal microbiota is necessary for the colonic genotoxicity of the food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in rats.

Brussels sprouts, inulin and fermented milk alter the faecal microbiota of human microbiota-associated rats as shown by PCR-temporal temperature gradient gel electrophoresis using universal, Lactobacillus and Bifidobacterium 16S rRNA gene primers

CCL20 Displays Antimicrobial Activity Against Cryptosporidium parvum, but Its Expression Is Reduced During Infection in the Intestine of Neonatal Mice.

Characterization of Cecal Microbiota and Response to an Orally Administered Lactobacillus Probiotic Strain in the Broiler Chicken

Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen

Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions

Commensal microbiota influence systemic autoimmune responses.

Constitutive delivery of bovine beta-lactoglobulin to the digestive tracts of gnotobiotic mice by engineered Lactobacillus casei

Consumption of Camembert cheese stimulates commensal enterococci in healthy human intestinal microbiota.

Delayed bacterial colonization of the gut alters the host immune response to oral sensitization against cow's milk proteins

Development of test systems for the detection of compounds that prevent the genotoxic effects of heterocyclic aromatic amines: preliminary results with constituents of cruciferous vegetables and other dietary constituents.

Dietary induction of phase II enzymes: a promising strategy for protection against DNA-reactive intermediates in man?

Effect of common Brassica vegetables (Brussels sprouts and red cabbage) on the development of preneoplastic lesions induced by 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in liver and colon of Fischer 344 rats

Effects of chair-restraint on gastrointestinal transit time and colonic fermentation in male rhesus monkey (Macaca mulatta).

Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.

Effects of the bacterial status of rats on the changes in some liver cytochrome P450 (EC 1.14.14.1) apoproteins consequent to a glucosinolate-rich diet

Eubacterium limosum activates isoxanthohumol from hops (Humulus lupulus L.) into the potent phytoestrogen 8-prenylnaringenin in vitro and in rat intestine

First evidences for a third sulfatase maturation system in prokaryotes from E. coli aslB and ydeM deletion mutants.

Formation of allyl isothiocyanate from sinigrin in the digestive tract of rats monoassociated with a human colonic strain of Bacteroides thetaiotaomicron

Germ-free C57BL/6J mice are resistant to high-fat-diet-induced insulin resistance and have altered cholesterol metabolism.

Glucosinolates and glucosinolate derivatives: implications for protection against chemical carcinogenesis.

Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system

Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research

Guidance for substantiating the evidence for beneficial effects of probiotics: impact of probiotics on digestive system metabolism

Gut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults

High fat diet drives obesity regardless the composition of gut microbiota in mice

Identification of new derivatives of sinigrin and glucotropaeolin produced by the human digestive microflora using 1H NMR spectroscopy analysis of in vitro incubations

Impact of bacteria in dairy products and of the intestinal microflora on the genotoxic and carcinogenic effects of heterocyclic aromatic amines

Increased induction of apoptosis by Propionibacterium freudenreichii TL133 in colonic mucosal crypts of human microbiota-associated rats treated with 1,2-dimethylhydrazine

Influence of cooking duration of cabbage and presence of colonic microbiota on the excretion of N-acetylcysteine conjugates of allyl isothiocyanate and bioactivity of phase 2 enzymes in F344 rats.

Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats

Interactions between the intestinal flora and xenobiotic metabolizing enzymes and their health consequences.

Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice

Intestinal microbiota contributes to individual susceptibility to alcoholic liver disease.

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice.

Intestinal microflora plays a crucial role in the genotoxicity of the cooked food mutagen 2-amino-3-methylimidazo [4,5-f]quinoline

Metabolic fate of ochratoxin A as a coffee contaminant in a dynamic simulator of the human colon.

Metabolism of sinigrin (2-propenyl glucosinolate) by the human colonic microflora in a dynamic in vitro large-intestinal model.

Microbial community development in a dynamic gut model is reproducible, colon region specific, and selective for Bacteroidetes and Clostridium cluster IX

Microbial metabolites control the thymic development of mucosal-associated invariant T cells

Modulation of the biological effects of glucosinolates by inulin and oat fibre in gnotobiotic rats inoculated with a human whole faecal flora

Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation.

Neonatal mono-colonization of germ-free mice with Lactobacillus casei enhances casein immunogenicity after oral sensitization to cow's milk.

Olfactory epithelium changes in germfree mice

Polymeric proanthocyanidins are catabolized by human colonic microflora into low-molecular-weight phenolic acids

Proanthocyanidins and human health: systemic effects and local effects in the gut.

Protective effects of Brussels sprouts, oligosaccharides and fermented milk towards 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced genotoxicity in the human flora associated F344 rat: role of xenobiotic metabolising enzymes and intestinal micr

Rape-seed meal toxicity in gnotobiotic rats: influence of a whole human faecal flora or single human strains of Escherichia coli and Bacteroides vulgatus.

Role of the Gut Microbiota in the Pathophysiology of Autism Spectrum Disorder: Clinical and Preclinical Evidence

Semi-automated solid-phase extraction method for studying the biodegradation of ochratoxin A by human intestinal microbiota

Short-chain fatty acids and polyamines in the pathogenesis of necrotizing enterocolitis: Kinetics aspects in gnotobiotic quails

Short-chain fructo-oligosaccharides modulate intestinal microbiota and metabolic parameters of humanized gnotobiotic diet induced obesity mice

Survival and metabolic activity of selected strains of Propionibacterium freudenreichii in the gastrointestinal tract of human microbiota-associated rats

Survival of Bifidobacterium animalis DN-173 010 in the Faecal Microbiota after Administration in Lyophilised Form or in Fermented Product – A Randomised Study in Healthy Adults

The activities of several detoxication enzymes are differentially induced by juices of garden cress, water cress and mustard in human HepG2 cells.

The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine

Tigloyl-CoA:pseudotropine acyl transferase—An enzyme of tropane alkaloid biosynthesis

Validation of fluorescent in situ hybridization combined with flow cytometry for assessing interindividual variation in the composition of human fecal microflora during long-term storage of samples

Variations in digestive physiology of rats after short duration flights aboard the US space shuttle

Wine constituents inhibit thrombosis but not atherogenesis in C57BL/6 apolipoprotein E-deficient mice