List of works by Tin-Lap Lee

A novel nuclear factor-kappaB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status

scientific article published on October 2007

A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas

scientific article published on 01 May 2008

Accessing the genomic effects of naked nanoceria in murine neuronal cells.

scientific article published on September 2011

Age affects gene expression in mouse spermatogonial stem/progenitor cells.

scientific article

Alterations of frizzled (FzE3) and secreted frizzled related protein (hsFRP) expression in gastric cancer.

scientific article published in December 2001

Application of convolutional neural network on early human embryo segmentation during in vitro fertilization

scientific article published on 24 January 2021

Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes

scientific article

Assessing the safety of nanomaterials by genomic approach could be another alternative

scientific article published on 01 December 2009

Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer.

scientific article published on February 2001

Big data: open-source format needed to aid wiki collaboration

scientific article published on September 2008

Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways

scientific article

DNA methylation of cancer genome.

scientific article

Detection of epigenetic alterations using tiling arrays.

scientific article published in January 2013

Developmental staging of male murine embryonic gonad by SAGE analysis

scientific article

Differential bortezomib sensitivity in head and neck cancer lines corresponds to proteasome, nuclear factor-kappaB and activator protein-1 related mechanisms.

scientific article published on July 2008

Differential methylation of imprinted genes in growth-restricted placentas

scientific article published on 21 June 2011

Distinctive molecular features of regenerative stem cells in the damaged male germline

scientific article published on 06 May 2022

Donation of mitochondria by iPSC-derived mesenchymal stem cells protects retinal ganglion cells against mitochondrial complex I defect-induced degeneration

scientific article published on 13 April 2019

Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging.

scientific article

Enhancement of oxaliplatin sensitivity in human colorectal cancer by hypericin mediated photodynamic therapy via ROS-related mechanism.

scientific article published on 7 December 2015

Epigenetic modification of SOCS-1 differentially regulates STAT3 activation in response to interleukin-6 receptor and epidermal growth factor receptor signaling through JAK and/or MEK in head and neck squamous cell carcinomas

scientific article published on 01 January 2006

Epigenetics dynamics in development and disease

scientific article published on 13 July 2015

Expression and cellular localization of COX-1 and -2 in Helicobacter pylori gastritis

scientific article published on 01 February 2001

From Peer-Reviewed to Peer-Reproduced in Scholarly Publishing: The Complementary Roles of Data Models and Workflows in Bioinformatics

scientific article

Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells.

scientific article published on 21 March 2018

Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer

scientific article

Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-kappaB and other signal transcription factors in head and neck squamous cell carcinoma.

scientific article published in January 2007

Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma.

scientific article published on 05 October 2016

Genomic landscape of developing male germ cells

scientific article

GermSAGE: a comprehensive SAGE database for transcript discovery on male germ cell development.

scientific article

GermlncRNA: a unique catalogue of long non-coding RNAs and associated regulations in male germ cell development.

scientific article

GonadSAGE: a comprehensive SAGE database for transcript discovery on male embryonic gonad development

scientific article

Hypermethylation of genes in testicular embryonal carcinomas

scientific article published on December 2015

Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.

scientific article published on June 2003

Identification of novel long noncoding RNA transcripts in male germ cells

scientific article published on January 2012

Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons

scientific article published on 29 June 2016

Integrative gene network analysis provides novel regulatory relationships, genetic contributions and susceptible targets in autism spectrum disorders

scientific article published on 26 January 2012

Interaction of Helicobacter pylori eradication and non-steroidal anti-inflammatory drugs on gastric epithelial apoptosis and proliferation: implications on ulcerogenesis

scientific article published on 01 July 2000

Inverse association between cyclooxygenase-2 overexpression and microsatellite instability in gastric cancer

scientific article published on 01 July 2001

L3MBTL2 regulates chromatin remodeling during spermatogenesis

scientific article published on 13 February 2019

Long noncoding RNAs in spermatogenesis: insights from recent high-throughput transcriptome studies

scientific article published on 08 April 2014

Long-term vitamin A deficiency induces alteration of adult mouse spermatogenesis and spermatogonial differentiation: direct effect on spermatogonial gene expression and indirect effects via somatic cells

scientific article published on 17 December 2012

Mapping genomic features of tiling microarray data by TileMapper

scientific article

Medicinal mushroom extracts inhibit ras-induced cell transformation and the inhibitory effect requires the presence of normal cells

scientific article published on July 2004

Metastatic squamous cell carcinoma cells that overexpress c-Met exhibit enhanced angiogenesis factor expression, scattering and metastasis in response to hepatocyte growth factor

scientific article published in August 2004

Methylation of an intronic region regulates miR-199a in testicular tumor malignancy

scientific article

Methylation profiling using methylated DNA immunoprecipitation and tiling array hybridization.

scientific article published on January 2012

MicroRNA-26b promotes transition from Kit- to Kit+ mouse spermatogonia

scientific article published on 25 September 2018

MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells.

scientific article

MicroRNAs mediated targeting on the Yin-yang dynamics of DNA methylation in disease and development

scientific article published on 12 May 2015

Molecular characteristics of early-stage female germ cells revealed by RNA sequencing of low-input cells and analysis of genome-wide DNA methylation

scientific article published on 01 April 2019

Molecular mechanisms of regulation and action of microRNA-199a in testicular germ cell tumor and glioblastomas

scientific article

Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway.

scientific article published on 14 March 2015

Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma.

scientific article

Promoter hypermethylation of tumor-related genes in gastric intestinal metaplasia of patients with and without gastric cancer.

scientific article

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma

scientific article

Revealing cellular and molecular transitions in neonatal germ cell differentiation using single cell RNA sequencing

scientific article published on 27 March 2019

Revealing the transcriptome landscape of mouse spermatogonial cells by tiling microarray

scientific article

Single cell genomics

scientific article published on 30 August 2019

Somatic β-catenin mutation in gastric carcinoma – an infrequent event that is not specific for microsatellite instability

scientific article published on 01 February 2001

TSPY potentiates cell proliferation and tumorigenesis by promoting cell cycle progression in HeLa and NIH3T3 cells

scientific article

Targeted disruption of Ing2 results in defective spermatogenesis and development of soft-tissue sarcomas

scientific article

The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors.

scientific article published on 22 May 2007

The complexity of antisense transcription revealed by the study of developing male germ cells.

scientific article published on 3 February 2006

The molecular signature of spermatogonial stem/progenitor cells in the 6-day-old mouse testis.

scientific article published on 23 December 2008

The proto-oncogene tyrosine protein kinase Src is essential for macrophage-myofibroblast transition during renal scarring.

scientific article published on 14 October 2017

Transcriptome analyses of male germ cells with serial analysis of gene expression (SAGE).

scientific article

Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation

scientific article published on 08 July 2021

Turning pipe dreams into reality

scientific article

Up-regulation of cyclooxygenase-1 and -2 in human gastric ulcer

scientific article published on 01 January 2001

Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer.

scientific article published on 12 February 2013

Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis.

scientific article published on 23 February 2011

Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

scientific article published on 21 January 2016

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