List of works - Natalie Verstraeten

A Historical Perspective on Bacterial Persistence.

scientific article published on January 2016

A Mutant Isoform of ObgE Causes Cell Death by Interfering with Cell Division

scientific article published on 28 June 2017

A Single-Amino-Acid Substitution in Obg Activates a New Programmed Cell Death Pathway in Escherichia coli

scientific article published on 22 December 2015

A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.

scientific article

Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

scientific article published on 2 May 2017

An integrative view of cell cycle control in Escherichia coli

scientific article published on 22 January 2018

Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.

scientific article

Bacterial Obg proteins: GTPases at the nexus of protein and DNA synthesis.

scientific article published on 28 March 2013

Biochemical determinants of ObgE-mediated persistence

scientific article published on 18 September 2019

CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing.

scientific article

Cell surface properties determine persistence of Pseudomonas aeruginosa

scientific article published on 01 January 2011

Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation.

scientific article published on 24 December 2015

Derivatives of the mouse cathelicidin-related antimicrobial peptide (CRAMP) inhibit fungal and bacterial biofilm formation

scientific article published on 30 June 2014

Elucidating the structure-function relationship of a bacterial GTPase in DNA replication through random mutagenesis

scientific article published on 01 January 2011

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa ⬇️

scientific article

Fitness trade-offs explain low levels of persister cells in the opportunistic pathogen Pseudomonas aeruginosa.

scientific article published on 17 March 2015

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

scientific article published on 7 March 2016

Fungal β-1,3-glucan increases ofloxacin tolerance of Escherichia coli in a polymicrobial E. coli/Candida albicans biofilm.

scientific article published on 9 March 2015

GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE

scientific article published on 18 December 2019

General Mechanisms Leading to Persister Formation and Awakening

scientific article published on 27 April 2019

Genome-Wide Association Study Reveals Host Factors Affecting Conjugation in Escherichia coli

scientific article published in 2022

HokB Monomerization and Membrane Repolarization Control Persister Awakening

scientific article published on 18 July 2019

Identification of novel persistence genes in Pseudomonas aeruginosa in the combat against emerging antimicrobial resistance.

scientific article

In Vitro Emergence of High Persistence upon Periodic Aminoglycoside Challenge in the ESKAPE Pathogens

scientific article published on 16 May 2016

In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans

scientific article published on 12 January 2017

Living on a surface: swarming and biofilm formation.

scientific article published on 03 September 2008

Membrane depolarization-triggered responsive diversification leads to antibiotic tolerance.

scientific article published on 24 July 2015

Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.

scientific article published on 22 August 2016

Molecular mechanisms and clinical implications of bacterial persistence

scientific article published on 15 October 2016

Network-Based Identification of Adaptive Pathways in Evolved Ethanol-Tolerant Bacterial Populations.

scientific article published on 28 August 2017

New approaches to combat Porphyromonas gingivalis biofilms.

scientific article published on 15 March 2017

New-found fundamentals of bacterial persistence.

scientific article published on 05 September 2012

Novel persistence genes in Pseudomonas aeruginosa identified by high-throughput screening.

scientific article

Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.

scientific article published on 4 June 2015

Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo

scientific article

Pseudomonas aeruginosa fosfomycin resistance mechanisms affect non-inherited fluoroquinolone tolerance

scientific article

Reactive oxygen species do not contribute to ObgE*-mediated programmed cell death

scientific article

Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

scientific article published on 7 April 2017

Repurposing Toremifene for Treatment of Oral Bacterial Infections.

scientific article published on 19 December 2016

Rhizobium etli HrpW is a pectin-degrading enzyme and differs from phytopathogenic homologues in enzymically crucial tryptophan and glycine residues.

scientific article published on 28 May 2009

Spectroscopic characterization of Venus at the single molecule level.

scientific article

Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence.

scientific article published on 21 February 2017

Surface tension gradient control of bacterial swarming in colonies of Pseudomonas aeruginosa

The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest.

scientific article

The Persistence-Inducing Toxin HokB Forms Dynamic Pores That Cause ATP Leakage

scientific article published on 14 August 2018

The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death.

scientific article published on 16 March 2016

The universally conserved prokaryotic GTPases

scientific article

List of works by Natalie Verstraeten

A Historical Perspective on Bacterial Persistence.

A Mutant Isoform of ObgE Causes Cell Death by Interfering with Cell Division

A Single-Amino-Acid Substitution in Obg Activates a New Programmed Cell Death Pathway in Escherichia coli

A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.

Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli

An integrative view of cell cycle control in Escherichia coli

Antibacterial activity of a new broad-spectrum antibiotic covalently bound to titanium surfaces.

Bacterial Obg proteins: GTPases at the nexus of protein and DNA synthesis.

Biochemical determinants of ObgE-mediated persistence

CRISPR-FRT targets shared sites in a knock-out collection for off-the-shelf genome editing.

Cell surface properties determine persistence of Pseudomonas aeruginosa

Covalent immobilization of antimicrobial agents on titanium prevents Staphylococcus aureus and Candida albicans colonization and biofilm formation.

Derivatives of the mouse cathelicidin-related antimicrobial peptide (CRAMP) inhibit fungal and bacterial biofilm formation

Elucidating the structure-function relationship of a bacterial GTPase in DNA replication through random mutagenesis

Elucidation of the Mode of Action of a New Antibacterial Compound Active against Staphylococcus aureus and Pseudomonas aeruginosa ⬇️

Fitness trade-offs explain low levels of persister cells in the opportunistic pathogen Pseudomonas aeruginosa.

Frequency of antibiotic application drives rapid evolutionary adaptation of Escherichia coli persistence

Fungal β-1,3-glucan increases ofloxacin tolerance of Escherichia coli in a polymicrobial E. coli/Candida albicans biofilm.

GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE

General Mechanisms Leading to Persister Formation and Awakening

Genome-Wide Association Study Reveals Host Factors Affecting Conjugation in Escherichia coli

HokB Monomerization and Membrane Repolarization Control Persister Awakening

Identification of novel persistence genes in Pseudomonas aeruginosa in the combat against emerging antimicrobial resistance.

In Vitro Emergence of High Persistence upon Periodic Aminoglycoside Challenge in the ESKAPE Pathogens

In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans

Living on a surface: swarming and biofilm formation.

Membrane depolarization-triggered responsive diversification leads to antibiotic tolerance.

Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.

Molecular mechanisms and clinical implications of bacterial persistence

Network-Based Identification of Adaptive Pathways in Evolved Ethanol-Tolerant Bacterial Populations.

New approaches to combat Porphyromonas gingivalis biofilms.

New-found fundamentals of bacterial persistence.

Novel persistence genes in Pseudomonas aeruginosa identified by high-throughput screening.

Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.

Oral administration of the broad-spectrum antibiofilm compound toremifene inhibits Candida albicans and Staphylococcus aureus biofilm formation in vivo

Pseudomonas aeruginosa fosfomycin resistance mechanisms affect non-inherited fluoroquinolone tolerance

Reactive oxygen species do not contribute to ObgE*-mediated programmed cell death

Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

Repurposing Toremifene for Treatment of Oral Bacterial Infections.

Rhizobium etli HrpW is a pectin-degrading enzyme and differs from phytopathogenic homologues in enzymically crucial tryptophan and glycine residues.

Spectroscopic characterization of Venus at the single molecule level.

Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence.

Surface tension gradient control of bacterial swarming in colonies of Pseudomonas aeruginosa

The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest.

The Persistence-Inducing Toxin HokB Forms Dynamic Pores That Cause ATP Leakage

The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death.

The universally conserved prokaryotic GTPases