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List of works by Luis Miguel Garcia-Segura

17α-Oestradiol-induced neuroprotection in the brain of spontaneously hypertensive rats

scientific article published on 01 May 2014

17β-estradiol--a new modulator of neuroglobin levels in neurons: role in neuroprotection against H₂O₂-induced toxicity.

scientific article published on January 2010

17β‐Oestradiol Anti‐Inflammatory Effects in Primary Astrocytes Require Oestrogen Receptor β‐Mediated Neuroglobin Up‐Regulation ⬇️

scientific article published on March 1, 2013

4'-Chlorodiazepam is neuroprotective against amyloid-beta in organotypic hippocampal cultures.

scientific article published on 22 April 2017

4'-Chlorodiazepam is neuroprotective against amyloid-beta through the modulation of survivin and bax protein expression in vitro

scientific article published on 17 December 2015

4'-Chlorodiazepam modulates the development of primary hippocampal neurons in a sex-dependent manner.

scientific article published on 29 December 2016

A CRM1-mediated nuclear export signal is essential for cytoplasmic localization of neurogenin 3 in neurons.

scientific article

A histochemical investigation on mucopolysaccharides in the dog sympathetic ganglia ⬇️

scientific article published on January 1976

A new mathematical function to evaluate neuronal morphology using the Sholl analysis

scientific article published on 3 February 2014

Acute experimental autoimmune encephalomyelitis induces sex dimorphic changes in neuroactive steroid levels.

scientific article published on 20 September 2009

Administration of an inhibitor of estrogen biosynthesis facilitates working memory acquisition in male rats

scientific article published on 31 March 2007

Adverse effects of 5α-reductase inhibitors: What do we know, don't know, and need to know?

scientific article published on 23 August 2015

African green monkeys have sexually dimorphic and estrogen-sensitive hypothalamic neuronal membranes

scientific article

Age-related changes in neuroactive steroid levels in 3xTg-AD mice.

scientific article published on 2 November 2012

An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat.

scientific article published in August 2003

An in vitro experimental model of neuroinflammation: the induction of interleukin-6 in murine astrocytes infected with Theiler's murine encephalomyelitis virus, and its inhibition by oestrogenic receptor modulators

scientific article published on 13 May 2011

Anatomically Specific Changes in the Expression of Somatostatin, Growth Hormone-Releasing Hormone and Growth Hormone Receptor mRNA in Diabetic Rats

scientific article published on 01 January 2000

Antidepressive and anxiolytic activity of selective estrogen receptor modulators in ovariectomized mice submitted to chronic unpredictable stress.

scientific article published on 29 October 2011

Antisense oligodeoxynucleotides for estrogen receptor-beta and alpha attenuate estradiol's modulation of affective and sexual behavior, respectively

scientific article

Aromatase distribution in the monkey temporal neocortex and hippocampus

scientific article published on 5 March 2008

Aromatase expression by astrocytes after brain injury: implications for local estrogen formation in brain repair

scientific article published in March 1999

Aromatase expression by reactive astroglia is neuroprotective.

scientific article published on December 2003

Aromatase expression in the human temporal cortex.

scientific article published on 19 January 2006

Aromatase expression in the normal and epileptic human hippocampus

scientific article published on 6 October 2009

Aromatase in the brain: not just for reproduction anymore.

scientific article published on June 2008

Aromatase inhibition exacerbates pain and reactive gliosis in the dorsal horn of the spinal cord of female rats caused by spinothalamic tract injury

scientific article published on 8 August 2014

Aromatase, the enzyme responsible for estrogen biosynthesis, is expressed by human and rat glioblastomas.

scientific article published on September 2004

Aromatase: a neuroprotective enzyme ⬇️

scientific article published on September 1, 2003

Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease.

scientific article

Astrocytic shape and glial fibrillary acidic protein immunoreactivity are modified by estradiol in primary rat hypothalamic cultures

scientific article published on 01 June 1989

Astroglial induction of in vivo angiogenesis.

scientific article published on January 1994

Behavioral effects of estradiol therapy in ovariectomized rats depend on the age when the treatment is initiated

scientific article published on 29 October 2011

Blockade of cannabinoid CB(1) receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity.

scientific article published in July 2002

Brain aromatase expression after experimental stroke: topography and time course

scientific article published in June 2005

Brain steroidogenesis: emerging therapeutic strategies to prevent neurodegeneration.

scientific article

CB2 cannabinoid receptor is involved in the anti-inflammatory effects of leptin in a model of traumatic brain injury

scientific article

Cajal and glial cells

scientific article published in January 2002

Carbonic anhydrase is associated with taste buds in rat tongue

scientific article published in December 1984

Carbonic anhydrase is present in olfactory receptor cells

scientific article published on 01 January 1984

Cellular and developmental distribution of the Na,K-ATPase beta subunit isoforms of neural tissues

scientific article

Cellular composition of the adult rat anterior pituitary is influenced by the neonatal sex steroid environment

scientific article published in September 1998

Cellular phenotype of androgen receptor-immunoreactive nuclei in the developing and adult rat brain

scientific article published in November 2005

Cerebellin 4, a synaptic protein, enhances inhibitory activity and resistance of neurons to amyloid-β toxicity.

scientific article published on 15 November 2014

Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficit

scientific article published on 3 June 2015

Changes of rat striatal neuronal membrane morphology and steroid content during the estrous cycle

scientific article

Chronic unpredictable stress and long-term ovariectomy affect arginine-vasopressin expression in the paraventricular nucleus of adult female mice

scientific article

Classical androgen receptors in non-classical sites in the brain.

scientific article published on 6 March 2008

Climbing fiber deafferentation reduces insulin-like growth factor I (IGF-I) content in cerebellum ⬇️

scientific article published on November 15, 1991

Climbing fiber destruction affects dendrite and spine membrane organization in Purkinje cells

scientific article published in March 1982

Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease

scientific article

Colchicine injection in the inferior olivary nucleus increases the number of Purkinje cell dendritic spines

scientific article published in August 1983

Comparison of plasma and cerebrospinal fluid levels of neuroactive steroids with their brain, spinal cord and peripheral nerve levels in male and female rats.

scientific article published on 21 May 2013

Conformation of brain proteolipid apoprotein. Effects of sonication and n-octyl-beta-D-glucopyranoside detergent.

scientific article

Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain.

scientific article published on 07 September 2007

Correlation of brain levels of progesterone and dehydroepiandrosterone with neurological recovery after traumatic brain injury in female mice.

scientific article published on 3 March 2015

Cortical spreading depression in traumatic brain injuries: is there a role for astrocytes?

scientific article published on 03 January 2014

Cross-talk between estrogen receptors and insulin-like growth factor-I receptor in the brain: cellular and molecular mechanisms.

scientific article published on 16 October 2006

Cycloheximide mimics effects of oestradiol that are linked to synaptic plasticity of hypothalamic neurons

scientific article

Dehydroepiandrosterone protects male and female hippocampal neurons and neuroblastoma cells from glucose deprivation.

scientific article published on 9 May 2016

Dehydroepiandrosterone regulates astroglia reaction to denervation of olfactory glomeruli

scientific article published in November 2004

Dehydroepiandrosterone regulates insulin-like growth factor-1 system in adult rat hypothalamus

scientific article published in March 2002

Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury

scientific article published in April 1999

Developmental Sex Differences in the Metabolism of Cardiolipin in Mouse Cerebral Cortex Mitochondria

scientific article (publication date: 6 March 2017)

Developmental sex differences and effect of ovariectomy on the number of cortical pyramidal cell dendritic spines

scientific article published in May 1990

Developmental-related changes in the lectin binding to cells of the central nervous system ⬇️

scientific article published on January 1979

Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation

scientific article published on 7 December 2011

Diabetic neuropathic pain: a role for testosterone metabolites

scientific article published on 07 March 2014

Diaminobenzidine oxidation in cerebellar histological sections ⬇️

scientific article published on January 1, 1978

Differential expression and gonadal hormone regulation of histone H1(0) in the developing and adult rat brain

scientific article published in May 1993

Dihydrotestosterone as a Protective Agent in Chronic Experimental Autoimmune Encephalomyelitis.

scientific article published on 26 February 2015

Distribution of nuclear pores and chromatin organization in neurons and glial cells of the rat cerebellar cortex

scientific article published on 01 December 1989

Down-regulation of Bcl-2 in rat substantia nigra after focal cerebral ischemia

scientific article published in June 2004

Early maternal deprivation in rats induces gender-dependent effects on developing hippocampal and cerebellar cells

scientific article published on 20 January 2009

Effect of short-and long-term gonadectomy on neuroactive steroid levels in the central and peripheral nervous system of male and female rats.

scientific article published in November 2010

Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain.

scientific article published on 9 December 2015

Effects of climbing fiber destruction on large dendrite spines of Purkinje cells

scientific article published in January 1982

Effects of progesterone and its reduced metabolites, dihydroprogesterone and tetrahydroprogesterone, on the expression and phosphorylation of glycogen synthase kinase-3 and the microtubule-associated protein tau in the rat cerebellum

scientific article

Effects of selective estrogen receptor modulators on allocentric working memory performance and on dendritic spines in medial prefrontal cortex pyramidal neurons of ovariectomized rats

scientific article published on 21 January 2012

Endo-exocytotic images and changes in synaptic transmission induced by diamide at a cholinergic junction

scientific article published on 01 January 1990

Endocrine glia: roles of glial cells in the brain actions of steroid and thyroid hormones and in the regulation of hormone secretion.

scientific article published on April 1996

Endogenous estrogen formation is neuroprotective in model of cerebellar ataxia

scientific article published in June 2003

Estradiol Decreases Cortical Reactive Astrogliosis after Brain Injury by a Mechanism Involving Cannabinoid Receptors

scientific article published on 21 January 2011

Estradiol Meets Notch Signaling in Developing Neurons ⬇️

scientific article published on August 11, 2011

Estradiol Uses Different Mechanisms in Astrocytes from the Hippocampus of Male and Female Rats to Protect against Damage Induced by Palmitic Acid

scientific article

Estradiol activates beta-catenin dependent transcription in neurons

scientific article

Estradiol and soy extract increase the production of new cells in the dentate gyrus of old rats.

scientific article published on 2 April 2005

Estradiol and testosterone regulate arginine-vasopressin expression in SH-SY5Y human female neuroblastoma cells through estrogen receptors-α and -β.

scientific article published on 12 April 2013

Estradiol increases the number of nuclear pores in the arcuate neurons of the rat hypothalamus

scientific article published in January 1991

Estradiol induces plasticity of gabaergic synapses in the hypothalamus

scientific article published on 01 March 1993

Estradiol induces rapid remodelling of plasma membranes in developing rat cerebrocortical neurons in culture

scientific article published on 01 October 1989

Estradiol inhibits GSK3 and regulates interaction of estrogen receptors, GSK3, and beta-catenin in the hippocampus

scientific article published in March 2004

Estradiol prevents neural tau hyperphosphorylation characteristic of Alzheimer's disease

scientific article published on June 2005

Estradiol promotes cell shape changes and glial fibrillary acidic protein redistribution in hypothalamic astrocytes in vitro: a neuronal-mediated effect

scientific article

Estradiol promotes spine growth and synapse formation without affecting pre-established networks

scientific article published on 06 October 2010

Estradiol promotion of changes in the morphology of astroglia growing in culture depends on the expression of polysialic acid of neural membranes

scientific article

Estradiol, insulin-like growth factor-I and brain aging.

scientific article published on 6 July 2007

Estradiol--induced redistribution of glial fibrillary acidic protein immunoreactivity in the rat brain

scientific article published on 01 March 1987

Estrogen and brain vulnerability

scientific article published in May 2002

Estrogen dissociates Tau and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor subunit in postischemic hippocampus.

scientific article published in August 2006

Estrogen induces synaptic plasticity in adult primate neurons.

scientific article published in May 1993

Estrogen receptor alpha forms estrogen-dependent multimolecular complexes with insulin-like growth factor receptor and phosphatidylinositol 3-kinase in the adult rat brain

scientific article published in April 2003

Estrogen receptor alpha is involved in the estrogenic regulation of arginine vasopressin immunoreactivity in the supraoptic and paraventricular nuclei of ovariectomized rats.

scientific article published on 16 March 2010

Estrogen receptor ligands counteract cognitive deficits caused by androgen deprivation in male rats

scientific article published on 3 March 2011

Estrogen-induced synaptic remodelling in adult rat brain is accompanied by the reorganization of neuronal membranes.

scientific article published in November 1987

Estrogen-like effects of the mammary carcinogen 7,12-dimethylbenz(alpha)anthracene on hypothalamic neuronal membranes

scientific article published in April 1992

Estrogens are neuroprotective factors for hypertensive encephalopathy.

scientific article published on 13 April 2014

Estrogens regulate posttranslational modification of neural cell adhesion molecule during the estrogen-induced gonadotropin surge

scientific article published on 12 March 2009

Evaluation of neuroactive steroid levels by liquid chromatography–tandem mass spectrometry in central and peripheral nervous system: Effect of diabetes

scientific article published on 19 June 2007

Expression of histone H1° in transcriptionally activated supraoptic neurons

scientific article published in April 1995

Expression of insulin-like growth factor I by astrocytes in response to injury

scientific article published in October 1992

Expression of the beta 1 and beta 2(AMOG) subunits of the Na,K-ATPase in neural tissues: cellular and developmental distribution patterns.

scientific article published in January 1996

Extragonadal synthesis of estradiol is protective against kainic acid excitotoxic damage to the hippocampus

scientific article

Fluctuation of synapse density in the arcuate nucleus during the estrous cycle.

scientific article published on 8 December 2006

Formin1 mediates the induction of dendritogenesis and synaptogenesis by neurogenin3 in mouse hippocampal neurons

scientific journal article

Framework for sex differences in adolescent neurobiology: a focus on cannabinoids.

scientific article

Freeze-fracture characterization of proteolipid protein and basic protein of central nervous system myelin incorporated in liposomes

scientific article

Freeze-fracture cytochemistry of neuronal membranes: inhomogeneous distribution of filipin-sterol complexes in perikarya, dendrites and axons

scientific article published on 01 February 1982

Freeze-fracture of developing neuronal plasma membrane in postnatal cerebellum

scientific article published on 01 March 1981

Freeze-fracture organization of chromatin and cytoplasm in neurons and astroglia of rat cerebellar cortex

scientific article published in July 1991

G protein-coupled estrogen receptor is required for the neuritogenic mechanism of 17β-estradiol in developing hippocampal neurons

scientific journal article

Gap junctions in the hypothalamic arcuate neurons of ovariectomized and estradiol-treated rats

scientific article published on 01 January 1990

Gender differences in the long-term effects of chronic prenatal stress on the HPA axis and hypothalamic structure in rats

scientific article

Giant liposomes: a model system in which to obtain patch-clamp recordings of ionic channels

scientific article published in December 1990

Glia-neuron crosstalk in the neuroprotective mechanisms of sex steroid hormones

scientific article published on 15 January 2005

Glial and axonal perikaryal coverage and somatic spines in the posterodorsal medial amygdala of male and cycling female rats.

scientific article published on 30 March 2015

Glial cells and energy balance

scientific article

Glial expression of estrogen and androgen receptors after rat brain injury

scientific article

GluN2B N-methyl-D-aspartic acid receptor subunit mediates atorvastatin-Induced neuroprotection after focal cerebral ischemia.

scientific article published on 17 June 2014

Glycogen synthase kinase-3β/β-catenin signaling in the rat hypothalamus during the estrous cycle.

scientific article published on 13 February 2012

Glycoproteins and polyanions in the synapses of rat and mouse central nervous system

scientific article published on 01 January 1978

Gonadal hormone regulation of glial fibrillary acidic protein immunoreactivity and glial ultrastructure in the rat neuroendocrine hypothalamus

scientific article published in January 1994

Gonadal hormone regulation of insulin-like growth factor-I-like immunoreactivity in hypothalamic astroglia of developing and adult rats.

scientific article

Gonadal hormones affect neuronal vulnerability to excitotoxin-induced degeneration

scientific article published on 01 September 1999

Gonadal hormones and the control of reactive gliosis.

scientific article published on 28 February 2012

Gonadal hormones down-regulate reactive gliosis and astrocyte proliferation after a penetrating brain injury

scientific article published on 01 November 1993

Gonadal steroids as promoters of neuro-glial plasticity.

scientific article published on January 1994

Growth hormone prevents neuronal loss in the aged rat hippocampus.

scientific article published in May 2005

Harmaline-induced changes in plasma membrane of Purkinje cells: a trans-synaptic effect mediated by climbing fibers

scientific article published in May 1986

Histochemical study of mucopolysaccharides in the subthalamic region of rats ⬇️

scientific article published on January 1976

Histochemical study of the myelin-associated carbohydrates ⬇️

scientific article published on January 1, 1979

Hormonal enhancement of neuronal firing is linked to structural remodelling of excitatory and inhibitory synapses.

scientific article published in August 2002

Hormones and the brain

scientific article published on 01 February 2011

Immunohistochemical mapping of calcium-binding protein immunoreactivity in the rat central nervous system

scientific article published on 01 March 1984

Implication of the phosphatidylinositol-3 kinase/protein kinase B signaling pathway in the neuroprotective effect of estradiol in the striatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice

scientific article published on 24 January 2006

In search of neuroprotective therapies based on the mechanisms of estrogens

scientific article published on 01 May 2007

Increase in the number of presynaptic large intramembrane particles during synaptic transmission at the Torpedo nerve-electroplaque junction

scientific article published on 01 September 1986

Increased glucagon-like peptide-1 receptor expression in glia after mechanical lesion of the rat brain

scientific article published on 01 June 1999

Insertion of Escherichia coli alpha-haemolysin in lipid bilayers as a non-transmembrane integral protein: prediction and experiment

scientific article published on 01 February 1999

Insight into the molecular sex dimorphism of ischemic stroke in rat cerebral cortex: focus on neuroglobin, sex steroids and autophagy

scientific article published on 03 April 2020

Insulin modulates neuronal plasma membrane development in human fetal spinal cord neurons in culture

scientific article published on 01 April 1986

Insulin-like growth factor 1 reduces age-related disorders induced by prenatal stress in female rats

scientific article

Insulin-like growth factor I modulates c-Fos induction and astrocytosis in response to neurotoxic insult

scientific article published in January 1997

Insulin-like growth factor I receptors and estrogen receptors colocalize in female rat brain

scientific article published on 01 January 2000

Interaction of estrogen receptors with insulin-like growth factor-I and Wnt signaling in the nervous system.

scientific article published on 22 September 2009

Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation

scientific article published in September 1996

Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus.

scientific article

Interactions between neuroactive steroids and reelin haploinsufficiency in Purkinje cell survival.

scientific article published on 10 July 2009

Interactions of estradiol and insulin-like growth factor-I signalling in the nervous system: new advances.

scientific article published on January 2010

Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection

scientific article published on 01 November 2001

Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analysing neuroprotective mechanisms.

scientific article

Introduction to the special issue on neuroprotection by steroids: new perspectives

scientific article published on 01 May 2000

L-Type Calcium Channels Modulation by Estradiol

scientific article published on 15 August 2016

LXR and TSPO as new therapeutic targets to increase the levels of neuroactive steroids in the central nervous system of diabetic animals

scientific article published on 03 March 2012

Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral Neuropathy

scientific article published on 26 March 2015

Lateral distribution of intramembrane particles in Purkinje and granule cells of the rat cerebellar cortex

scientific article published in July 1984

Leptin uptake by serotonergic neurones of the dorsal raphe

scientific article published in June 2002

Levels and actions of neuroactive steroids in the nervous system under physiological and pathological conditions: Sex-specific features

scientific article

Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions.

scientific article published on 16 August 2013

Ligand for translocator protein reverses pathology in a mouse model of Alzheimer's disease

scientific article

Lipid-protein interaction. The incorporation of myelin proteolipid apoprotein into phosphatidylcholine bilayers

scientific article published on 01 July 1988

Localization of aspartate aminotransferase and glutamic dehydrogenase in the Edinger-Westphal and oculomotor nuclei of Lacerta lepida

scientific article published on 01 October 1977

Localization of the insulin-like growth factor I receptor in the cerebellum and hypothalamus of adult rats: an electron microscopic study

scientific article published in July 1997

Loss of sexual dimorphism in rat arcuate nucleus neuronal membranes with reproductive aging

scientific article published in April 1991

Maternal stress alters the developmental program of embryonic hippocampal neurons growing in vitro ⬇️

scientific article published on July 24, 2012

Microglial dependent protective effects of neuroactive steroids.

scientific article published on 2 February 2016

Milestones on Steroids and the Nervous System: 10 years of basic and translational research.

scientific article

Minireview: Role of glia in neuroendocrine function.

scientific article published on 11 December 2003

Molecular mechanisms involved in the regulation of neuritogenesis by estradiol: Recent advances.

scientific article published on 28 September 2011

Multimodal analysis in acute and chronic experimental autoimmune encephalomyelitis.

scientific article

NADPH-Diaphorase Colocalizes with GPER and Is Modulated by the GPER Agonist G1 in the Supraoptic and Paraventricular Nuclei of Ovariectomized Female Rats.

scientific article published on 9 March 2016

Natural fluctuation and gonadal hormone regulation of astrocyte immunoreactivity in dentate gyrus

scientific article

Neural-derived estradiol regulates brain plasticity

scientific article

Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy

scientific article published on 04 March 2014

Neuroactive steroids and peripheral neuropathy.

scientific article published on 6 May 2007

Neuroactive steroids and the peripheral nervous system: An update.

scientific article published on 28 March 2015

Neuroactive steroids influence peripheral myelination: a promising opportunity for preventing or treating age-dependent dysfunctions of peripheral nerves.

scientific article published on September 2003

Neuroactive steroids prevent peripheral myelin alterations induced by diabetes

scientific article published on 19 April 2006

Neuroactive steroids regulate astroglia morphology in hippocampal cultures from adult rats

scientific article published on 01 May 1995

Neuroactive steroids: focus on human brain

scientific article (publication date: 15 September 2011)

Neuroactive steroids: state of the art and new perspectives.

scientific article published on March 2008

Neuroanatomical relationship between type 1 cannabinoid receptors and dopaminergic systems in the rat basal ganglia

scientific article published in January 2003

Neuroendocrinology of childbirth and mother-child attachment: the basis of an etiopathogenic model of perinatal neurobiological disorders.

scientific article published on 03 April 2014

Neurogenesis in explants from the walls of the lateral ventricle of adult bovine brain: role of endogenous IGF-1 as a survival factor.

scientific article published in January 2003

Neurogenin 3 cellular and subcellular localization in the developing and adult hippocampus.

scientific article published in May 2010

Neurogenin 3 mediates sex chromosome effects on the generation of sex differences in hypothalamic neuronal development

scientific article

Neuronal membrane remodelling during the oestrus cycle: a freeze-fracture study in the arcuate nucleus of the rat hypothalamus

scientific article published on 01 June 1988

Neurons with whorl bodies have increased numbers of synapses

scientific article published in March 1985

Neuroplastic changes in the hypothalamic arcuate nucleus: the estradiol effect is accompanied by increased exoendocytotic activity of neuronal membranes

scientific article published in April 1996

Neuroprotection and Sex Steroid Hormones: Evidence of Estradiol- Mediated Protection in Hypertensive Encephalopathy ⬇️

scientific article published on October 1, 2012

Neuroprotection by estradiol.

scientific article

Neuroprotection by the steroids pregnenolone and dehydroepiandrosterone is mediated by the enzyme aromatase

scientific article published in September 2003

Neuroprotective Effects of Progesterone in Chronic Experimental Autoimmune Encephalomyelitis

scientific article published on 01 June 2012

Neuroprotective actions of estradiol revisited

scientific article published on 31 August 2011

Neuroprotective actions of selective estrogen receptor modulators.

scientific article published on December 2009

Neuroprotective and neurotoxic effects of estrogens

scientific article published in November 2003

Neuroprotective effects of a ligand of translocator protein-18 kDa (Ro5-4864) in experimental diabetic neuropathy.

scientific article

Neuroprotective effects of soy phytoestrogens in the rat brain

scientific article published in February 2006

Neuroprotective effects of the catalytic subunit of telomerase: A potential therapeutic target in the central nervous system.

scientific article published on 16 April 2016

New insights into estrogen action on the brain

scientific article

New steps forward in the neuroactive steroid field.

scientific article published on 19 March 2015

Non-Neuronal Cells in the Hypothalamic Adaptation to Metabolic Signals

scientific article published on 21 March 2017

Non-reproductive Functions of Aromatase in the Central Nervous System Under Physiological and Pathological Conditions

scientific article published on 06 August 2018

Notch/Neurogenin 3 Signalling is Involved in the Neuritogenic Actions of Oestradiol in Developing Hippocampal Neurones

scientific article published on 01 April 2011

Novel cellular phenotypes and subcellular sites for androgen action in the forebrain.

scientific article

Nuclear compartmentalization in transcriptionally activated hypothalamic neurons

scientific article published in January 1993

Nuclear pores in rat hypothalamic arcuate neurons: sex differences and changes during the oestrous cycle.

scientific article published in August 1987

Oestradiol synthesized by female neurons generates sex differences in neuritogenesis.

scientific article published on 24 August 2016

Oestrogen-induced changes in the synaptology of the monkey (Cercopithecus aethiops) arcuate nucleus during gonadotropin feedback.

scientific article published in January 2001

Performance in an escape task induces fos-like immunoreactivity in a specific area of the motor cortex of the rat.

scientific article published in July 1992

Phosphatidylinositol 3-kinase and glycogen synthase kinase 3 regulate estrogen receptor-mediated transcription in neuronal cells

scientific article published on 23 February 2006

Postsynaptic membrane domains in the molecular layer of the cerebellum: a correlation between presynaptic inputs and postsynaptic plasma membrane organization

scientific article published in November 1984

Prenatal stress increases the expression of proinflammatory cytokines and exacerbates the inflammatory response to LPS in the hippocampal formation of adult male mice

scientific article

Prenatal stress induces long-term effects in cell turnover in the hippocampus-hypothalamus-pituitary axis in adult male rats

scientific article published in 2011

Presynaptic effects of 4-aminopyridine and changes following a single giant impulse at the Torpedo nerve-electroplaque junction

scientific article published in August 1987

Profiling Neuroactive Steroid Levels After Traumatic Brain Injury in Male Mice.

scientific article published on 22 August 2016

Progesterone and its derivatives dihydroprogesterone and tetrahydroprogesterone reduce myelin fiber morphological abnormalities and myelin fiber loss in the sciatic nerve of aged rats.

scientific article published in October 2003

Progesterone as a regulator of phosphorylation in the central nervous system.

scientific article published on December 2010

Progesterone regulates the phosphorylation of protein phosphatases in the brain.

scientific article published on October 2010

Protection by Neuroglobin Expression in Brain Pathologies

scientific article

Rapid effects of gonadal steroids upon hypothalamic neuronal membrane ultrastructure

scientific article published in January 1987

Rapid stimulation of the PI3-kinase/Akt signalling pathway in developing midbrain neurones by oestrogen.

scientific article published in January 2002

Reduced metabolites mediate neuroprotective effects of progesterone in the adult rat hippocampus. The synthetic progestin medroxyprogesterone acetate (Provera) is not neuroprotective

scientific article published in August 2006

Reduced progesterone metabolites protect rat hippocampal neurones from kainic acid excitotoxicity in vivo

scientific article published in January 2004

Regional sex differences in spine density along the apical shaft of visual cortex pyramids during postnatal development

scientific article published in February 1991

Regulation of aromatase expression in the anterior amygdala of the developing mouse brain depends on ERβ and sex chromosome complement

scientific article

Regulation of astroglia by gonadal steroid hormones under physiological and pathological conditions

scientific article

Regulation of the phosphoinositide-3 kinase and mitogen-activated protein kinase signaling pathways by progesterone and its reduced metabolites in the rat brain

scientific journal article

Ro5-4864, a peripheral benzodiazepine receptor ligand, reduces reactive gliosis and protects hippocampal hilar neurons from kainic acid excitotoxicity.

scientific article

Role of astrocytes in the neuroprotective actions of 17β-estradiol and selective estrogen receptor modulators

scientific article published on 18 January 2014

Role of astroglia in the neuroplastic and neuroprotective actions of estradiol.

scientific article published on December 2010

Role of estrogen receptor alpha in membrane-initiated signaling in neural cells: interaction with IGF-1 receptor

scientific article published on 9 January 2009

Role of iron ions on tannin-iron method histochemical specificity (author's transl)

scientific article published on January 1, 1977

Role of neuroactive steroids in the peripheral nervous system

scientific article

Role of oestrogen receptors on the modulation of NADPH-diaphorase-positive cell number in supraoptic and paraventricular nuclei of ovariectomised female rats.

scientific article published in March 2013

Seasonal activation and inactivation of song motor memories in wild canaries is not reflected in neuroanatomical changes of forebrain song areas.

scientific article

Selective Estrogen Receptor Modulators Regulate Dendritic Spine Plasticity in the Hippocampus of Male Rats ⬇️

scientific article published on November 2, 2011

Selective Oestrogen Receptor Agonists Rescued Hippocampus Parameters in Male Spontaneously Hypertensive Rats.

scientific article published on 12 August 2016

Selective estrogen receptor modulators as brain therapeutic agents

scientific article published on 19 January 2011

Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro.

scientific article

Selective estrogen receptor modulators protect hippocampal neurons from kainic acid excitotoxicity: differences with the effect of estradiol

scientific article published in November 2004

Selective estrogen receptor modulators regulate reactive microglia after penetrating brain injury

scientific article

Selective localization of calcium-binding protein in human brainstem, cerebellum and spinal cord

scientific article published in December 1986

Selective oestrogen receptor (ER) modulators reduce microglia reactivity in vivo after peripheral inflammation: potential role of microglial ERs.

scientific article published on 6 May 2008

Selective transcriptional regulation of aromatase gene by vitamin D, dexamethasone, and mifepristone in human glioma cells

scientific article

Separation of specific fraction of synaptosomes by affinity chromatography

scientific article

Sex Differences and Effects of Estrogenic Compounds on the Expression of Inflammatory Molecules by Astrocytes Exposed to the Insecticide Dimethoate ⬇️

scientific article published on August 14, 2013

Sex chromosome complement determines sex differences in aromatase expression and regulation in the stria terminalis and anterior amygdala of the developing mouse brain.

scientific article published on 28 July 2015

Sex differences and maturational changes in arcuate nucleus neuronal plasma membrane organization.

scientific article

Sex differences in Parkinson's disease: Features on clinical symptoms, treatment outcome, sexual hormones and genetics

scientific article published on 30 September 2017

Sex differences in glia reactivity after cortical brain injury.

scientific article

Sex differences in neuroactive steroid levels in the nervous system of diabetic and non-diabetic rats.

scientific article

Sex differences in plasma membrane concanavalin A binding in the rat arcuate neurons

scientific article published on 01 April 1989

Sex differences in the injured brain.

scientific article published on October 2011

Sex differences in the manifestation of peripheral diabetic neuropathy in gonadectomized rats: a correlation with the levels of neuroactive steroids in the sciatic nerve.

scientific article published on 15 January 2011

Sex differences, developmental changes, response to injury and cAMP regulation of the mRNA levels of steroidogenic acute regulatory protein, cytochrome p450scc, and aromatase in the olivocerebellar system

scientific journal article

Sex steroid effects on the development and functioning of the growth hormone axis.

scientific article published on June 1996

Sex-dependent alterations in response to maternal deprivation in rats.

scientific article published on December 2009

Sex-dependent long-term effects of adolescent exposure to THC and/or MDMA on neuroinflammation and serotoninergic and cannabinoid systems in rats

scientific article

Sex-dimorphic effects of dehydroepiandrosterone in diabetic neuropathy.

scientific article published on 16 September 2011

Sex-dimorphic effects of progesterone and its reduced metabolites on gene expression of myelin proteins by rat Schwann cells.

scientific article published in June 2006

Sex-specific therapeutic strategies based on neuroactive steroids: In search for innovative tools for neuroprotection.

scientific article published on 12 June 2009

Sexual differences in the synaptic connectivity in the rat dentate gyrus

scientific article published on 01 October 1993

Sexual differentiation of synaptic connectivity and neuronal plasma membrane in the arcuate nucleus of the rat hypothalamus

scientific article published in September 1990

Sexual differentiation of the neuronal plasma membrane: neonatal levels of sex steroids modulate the number of exo-endocytotic images in the developing rat arcuate neurons

scientific article published on 01 August 1988

Sexual dimorphism and sex steroid modulation of glial fibrillary acidic protein messenger RNA and immunoreactivity levels in the rat hypothalamus

scientific article published in November 1995

Sexually Dimorphic Effect of Genistein on Hypothalamic Neuronal Differentiation in Vitro

scientific article published on 18 May 2019

Short-Term High-Fat Diet Feeding Provides Hypothalamic but Not Hippocampal Protection against Acute Infection in Male Mice.

scientific article published on 11 February 2016

Short-term effects of diabetes on neurosteroidogenesis in the rat hippocampus.

scientific article published on 23 November 2016

Signaling mechanisms mediating the regulation of synaptic plasticity and memory by estradiol

scientific article published on 25 April 2015

Space flight affects magnocellular supraoptic neurons of young prepuberal rats: transient and permanent effects.

scientific article published in October 2001

Specific neurons in chick central nervous system stain with an antibody against chick intestinal vitamin D-dependent calcium-binding protein

scientific article published on 01 October 1981

Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.

scientific article published on September 2003

Steroidogenic acute regulatory protein in the brain.

scientific article

Steroidogenic acute regulatory protein in the rat brain: cellular distribution, developmental regulation and overexpression after injury ⬇️

scientific article published on September 1, 2003

Steroids and glial cell function.

scientific article published on November 2006

Structural insights from GRP78-NF-κB binding interactions: a computational approach to understand a possible neuroprotective pathway in brain injuries

scientific article published on 18 December 2013

Sub-chronic exposure to the insecticide dimethoate induces a proinflammatory status and enhances the neuroinflammatory response to bacterial lypopolysaccharide in the hippocampus and striatum of male mice

scientific article published on 26 July 2013

Survivin prevents apoptosis by binding to caspase-3 in astrocytes infected with the BeAn strain of Theiler's murine encephalomyelitis virus.

scientific article

Synaptic remodeling in the arcuate nucleus during the estrous cycle is induced by estrogen and precedes the preovulatory gonadotropin surge

scientific article published in December 1996

Synaptic remodeling in the rat arcuate nucleus during the estrous cycle

scientific article published on 01 January 1989

Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats

scientific article published in February 1986

Synergistic interaction of estradiol and insulin-like growth factor-I in the activation of PI3K/Akt signaling in the adult rat hypothalamus

scientific article published in October 2002

Testosterone Protects Mitochondrial Function and Regulates Neuroglobin Expression in Astrocytic Cells Exposed to Glucose Deprivation

scientific article published on 27 June 2016

Testosterone decreases reactive astroglia and reactive microglia after brain injury in male rats: role of its metabolites, oestradiol and dihydrotestosterone.

scientific article

Testosterone derivatives are neuroprotective agents in experimental diabetic neuropathy

scientific article published on 01 May 2007

Testosterone-dependent increase of gap-junctions in HVC neurons of adult female canaries

scientific article

Tetanic stimulation of schaffer collaterals induces rhythmic bursts via NMDA receptor activation in rat CA1 pyramidal neurons

scientific article published in January 2002

The Selective Estrogen Receptor Modulator Raloxifene Regulates Arginine-Vasopressin Gene Expression in Human Female Neuroblastoma Cells Through G Protein-Coupled Estrogen Receptor and ERK Signaling.

scientific article published on 22 July 2015

The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury.

scientific article published on 26 March 2018

The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis

scientific article published in February 2003

The distribution of glial fibrillary acidic protein in the adult rat brain is influenced by the neonatal levels of sex steroids

scientific article published on 01 July 1988

The lipogenic regulator Sterol Regulatory Element Binding Factor-1c is required to maintain peripheral nerve structure and function.

scientific article published on 12 June 2015

The neuroprotective actions of oestradiol and oestrogen receptors

scientific article

The role of estradiol and progesterone in phased synaptic remodelling of the rat arcuate nucleus

scientific article

The role of glia in the hypothalamus: implications for gonadal steroid feedback and reproductive neuroendocrine output

scientific article published on April 2008

The role of glia in the neuroendocrine hypothalamus: possible implications in hormone secretion.

scientific article published on January 1996

The weight gain response to stress during adulthood is conditioned by both sex and prenatal stress exposure

scientific article published in September 2009

Theiler's virus infection provokes the overexpression of genes coding for the chemokine Ip10 (CXCL10) in SJL/J murine astrocytes, which can be inhibited by modulators of estrogen receptors.

scientific article published on 23 July 2014

Therapeutic actions of translocator protein (18 kDa) ligands in experimental models of psychiatric disorders and neurodegenerative diseases.

scientific article published on 19 July 2015

Therapeutic approaches to peripheral neuropathy based on neuroactive steroids

scientific article published in August 2006

Therapeutic implications of brain steroidogenesis

scientific article published in January 2010

Tibolone Preserves Mitochondrial Functionality and Cell Morphology in Astrocytic Cells Treated with Palmitic Acid.

scientific article

Tibolone Reduces Oxidative Damage and Inflammation in Microglia Stimulated with Palmitic Acid through Mechanisms Involving Estrogen Receptor Beta.

scientific article published on 25 September 2017

Tibolone protects T98G cells from glucose deprivation.

scientific article

Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression

scientific article published on 29 May 2016

Trans-synaptic modulation of Purkinje cell plasma membrane organization by climbing fiber axonal flow

scientific article published in January 1985

Transfer of Function to a Specific Area of the Cortex After Induced Recovery from Brain Damage

scientific article published in January 1992

Translocator protein 18 kDa is involved in the regulation of reactive gliosis

scientific article published on 01 November 2007

Transynaptic modulation by insulin-like growth factor I of dendritic spines in Purkinje cells.

scientific article published in October 1997

UCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behavior

scientific article

Ultrastructural alterations in plasma membranes from drug-resistant P388 murine leukemia cells.

scientific article published in November 1990

Upregulation of voltage-gated Ca2+ channels in mouse astrocytes infected with Theiler's murine encephalomyelitis virus (TMEV).

scientific article published on 3 June 2013

Verapamil reverses the ultrastructural alterations in the plasma membrane induced by drug resistance

scientific article published on December 21, 1992

X-linked histone H3K27 demethylase Kdm6a regulates sexually dimorphic differentiation of hypothalamic neurons

scientific article published on 11 October 2021

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