List of works - Nicholas P. Tatonetti

3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance

scientific article

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

scientific article published on 31 May 2016

A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports

article

A curated and standardized adverse drug event resource to accelerate drug safety research

scientific article

A database of pediatric drug effects to evaluate ontogenic mechanisms from child growth and development

scientific article published in 2022

A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports

scientific article published on 14 June 2011

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval

scientific article

An integrative method for scoring candidate genes from association studies: application to warfarin dosing

scientific article published on 28 October 2010

Associations between blood type and COVID-19 infection, intubation, and death

scientific article published on 13 November 2020

Birth month affects lifetime disease risk: a phenome-wide method

scientific article

Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest

scientific article

Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association

scientific article

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality

scientific article (publication date: October 2015)

Cooperative transcription factor associations discovered using regulatory variation

scientific article

Data science identifies novel drug interactions that prolong the QT interval

scholarly article published 16 August 2015

Data-driven prediction of drug effects and interactions

scientific article

Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

scientific article published on 25 May 2011

Detection of drug-drug interactions by modeling interaction profile fingerprints

scientific article

Development and validation of a classification approach for extracting severity automatically from electronic health records

scientific article

Disease risk factors identified through shared genetic architecture and electronic medical records

scientific article

Evaluating risk detection methods to uncover ontogenic-mediated adverse drug effect mechanisms in children

scientific article published in 2021

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

scientific article published on 05 June 2013

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes

scientific article (publication date: 2013)

High-throughput methods for combinatorial drug discovery

scientific article published on October 2013

Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

scientific article published on 03 August 2020

Impact of Major Bleeding on Long-Term Mortality in Anemic Versus Nonanemic Patients Undergoing Percutaneous Coronary Intervention Using Bivalirudin

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling

scientific article

Improving condition severity classification with an efficient active learning based framework

scientific article

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

scientific article published on 08 April 2014

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors.

scientific article

Interpretome: a freely available, modular, and secure personal genome interpretation engine

scientific article published on January 2012

Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review

scientific article

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

scientific article published on 15 April 2013

Mapping the effects of drugs on the immune system

scientific article

Melatonin is significantly associated with survival of intubated COVID-19 patients

scientific article published on 18 October 2020

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins

scientific article published on 29 April 2014

No population left behind: improving pediatric drug safety using informatics and systems biology

scientific article published on 17 December 2020

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

scientific article published on 16 February 2013

Outcomes Prediction via Time Intervals Related Patterns

Pathogen population structure can explain hospital outbreaks

scientific article published on 25 July 2018

Pathway analysis of genome-wide data improves warfarin dose prediction

scientific article

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

scientific article

Response to 'Use of an algorithm for identifying hidden drug-drug interactions in adverse event reports' by Gooden et al.

scientific article published on 30 January 2013

STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud

scientific article

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions

scientific article published on 20 April 2020

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

scientific article published on 12 March 2021

Similarity-based modeling applied to signal detection in pharmacovigilance.

scientific article

Similarity-based modeling in large-scale prediction of drug-drug interactions

scientific article

Stimulated reporting: the impact of US food and drug administration-issued alerts on the adverse event reporting system (FAERS)

scientific article

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

scientific article published on March 2014

Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps

scientific article published on 9 March 2021

Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

scientific article published on 12 November 2015

Systems pharmacology augments drug safety surveillance

scientific article

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing

scientific article (publication date: 2017)

Testing the association between blood type and COVID-19 infection, intubation, and death

scientific article published on 11 April 2020

The Weber effect and the United States Food and Drug Administration's Adverse Event Reporting System (FAERS): analysis of sixty-two drugs approved from 2006 to 2010.

scientific article published on April 2014

Toward a complete dataset of drug-drug interaction information from publicly available sources

scientific article (publication date: June 2015)

VenomKB v2.0: A knowledge repository for computational toxinology

VenomKB, a new knowledge base for facilitating the validation of putative venom therapies

scientific article

Web-scale pharmacovigilance: listening to signals from the crowd

scientific article

List of works by Nicholas P. Tatonetti

3D pharmacophoric similarity improves multi adverse drug event identification in pharmacovigilance

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

A Pharmacovigilance Signaling System Based on FDA Regulatory Action and Post-Marketing Adverse Event Reports

A curated and standardized adverse drug event resource to accelerate drug safety research

A database of pediatric drug effects to evaluate ontogenic mechanisms from child growth and development

A novel signal detection algorithm for identifying hidden drug-drug interactions in adverse event reports

An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval

An integrative method for scoring candidate genes from association studies: application to warfarin dosing

Associations between blood type and COVID-19 infection, intubation, and death

Birth month affects lifetime disease risk: a phenome-wide method

Bridging islands of information to establish an integrated knowledge base of drugs and health outcomes of interest

Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality

Cooperative transcription factor associations discovered using regulatory variation

Data science identifies novel drug interactions that prolong the QT interval

Data-driven prediction of drug effects and interactions

Detecting drug interactions from adverse-event reports: interaction between paroxetine and pravastatin increases blood glucose levels.

Detection of drug-drug interactions by modeling interaction profile fingerprints

Development and validation of a classification approach for extracting severity automatically from electronic health records

Disease risk factors identified through shared genetic architecture and electronic medical records

Evaluating risk detection methods to uncover ontogenic-mediated adverse drug effect mechanisms in children

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes

High-throughput methods for combinatorial drug discovery

Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

Impact of Major Bleeding on Long-Term Mortality in Anemic Versus Nonanemic Patients Undergoing Percutaneous Coronary Intervention Using Bivalirudin

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling

Improving condition severity classification with an efficient active learning based framework

Insight into the Functional and Structural Properties of 3-Arylcoumarin as an Interesting Scaffold in Monoamine Oxidase B Inhibition

Insight into the interactions between novel coumarin derivatives and human A3 adenosine receptors.

Interpretome: a freely available, modular, and secure personal genome interpretation engine

Investigation of 7-dehydrocholesterol reductase pathway to elucidate off-target prenatal effects of pharmaceuticals: a systematic review

MAO Inhibitory Activity of 2-Arylbenzofurans versus 3-Arylcoumarins: Synthesis, in vitro Study, and Docking Calculations

Mapping the effects of drugs on the immune system

Melatonin is significantly associated with survival of intubated COVID-19 patients

Monoamine Oxidase (MAO) Inhibitory Activity: 3-Phenylcoumarins versus 4-Hydroxy-3-phenylcoumarins

No population left behind: improving pediatric drug safety using informatics and systems biology

Novel (coumarin-3-yl)carbamates as selective MAO-B inhibitors: synthesis, in vitro and in vivo assays, theoretical evaluation of ADME properties and docking study

Outcomes Prediction via Time Intervals Related Patterns

Pathogen population structure can explain hospital outbreaks

Pathway analysis of genome-wide data improves warfarin dose prediction

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

Response to 'Use of an algorithm for identifying hidden drug-drug interactions in adverse event reports' by Gooden et al.

STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud

Shotgun Transcriptome and Isothermal Profiling of SARS-CoV-2 Infection Reveals Unique Host Responses, Viral Diversification, and Drug Interactions

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

Similarity-based modeling applied to signal detection in pharmacovigilance.

Similarity-based modeling in large-scale prediction of drug-drug interactions

Stimulated reporting: the impact of US food and drug administration-issued alerts on the adverse event reporting system (FAERS)

Synthesis, pharmacological study and docking calculations of new benzo[f]coumarin derivatives as dual inhibitors of enzymatic systems involved in neurodegenerative diseases

Systemic Tissue and Cellular Disruption from SARS-CoV-2 Infection revealed in COVID-19 Autopsies and Spatial Omics Tissue Maps

Systems biology approaches for identifying adverse drug reactions and elucidating their underlying biological mechanisms

Systems pharmacology augments drug safety surveillance

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing

Testing the association between blood type and COVID-19 infection, intubation, and death

The Weber effect and the United States Food and Drug Administration's Adverse Event Reporting System (FAERS): analysis of sixty-two drugs approved from 2006 to 2010.

Toward a complete dataset of drug-drug interaction information from publicly available sources

VenomKB v2.0: A knowledge repository for computational toxinology

VenomKB, a new knowledge base for facilitating the validation of putative venom therapies

Web-scale pharmacovigilance: listening to signals from the crowd