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List of works by Simon M. Laws

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease

scientific article published on 19 December 2018

A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.

scientific article published on 6 July 2006

A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer’s disease and gastrointestinal tract disorders

scientific article published in 2022

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis.

scientific article published on 17 July 2015

APOE and BDNF polymorphisms moderate amyloid β-related cognitive decline in preclinical Alzheimer's disease.

scientific article published on 7 October 2014

APOE-epsilon4 and APOE -491A polymorphisms in individuals with subjective memory loss

scientific article published in January 2002

APOEɛ4 Genotype, Amyloid, and Clinical Disease Progression in Cognitively Normal Older Adults

scientific article

Alzheimer's Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-β Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study

scientific article published on August 2015

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies

scientific article published in January 2018

Alzheimer's disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology

scientific article

Amyloid burden and incident depressive symptoms in preclinical Alzheimer's disease.

scientific article published on 3 January 2018

Amyloid β-associated cognitive decline in the absence of clinical disease progression and systemic illness

scientific article published on 9 June 2017

Apolipoprotein D levels are elevated in prefrontal cortex of subjects with Alzheimer’s disease

Apolipoprotein E4 is associated with reduced calcaneal quantitative ultrasound measurements and bone mineral density in elderly women

scientific article published on 01 October 2002

Association between presenilin-1 Glu318Gly mutation and familial Alzheimer's disease in the Australian population.

scientific article

Association between the presenilin-1 mutation Glu318Gly and complaints of memory impairment

scientific article published in January 2002

Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease

scientific article published on 20 August 2008

Association of cardiovascular factors and Alzheimer's disease plasma amyloid-beta protein in subjective memory complainers

scientific article

Association of plasma Aß peptides with blood pressure in the elderly

scientific article (publication date: 15 April 2011)

Association of the tau haplotype H2 with age at onset and functional alterations of glucose utilization in frontotemporal dementia.

scientific article published in October 2007

Association of β-Amyloid and Apolipoprotein E ε4 With Memory Decline in Preclinical Alzheimer Disease.

scientific article published on 22 January 2018

Association of β-amyloid level, clinical progression and longitudinal cognitive change in normal older individuals

scientific article published on 12 November 2020

Association study between the D10S1423 microsatellite marker and Alzheimer's disease

scientific article published on 18 July 2005

Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease.

scientific article published on 23 October 2012

Associations of Dietary Protein and Fiber Intake with Brain and Blood Amyloid-β.

scientific article published in January 2018

Aβ-related memory decline in APOE ε4 noncarriers: Implications for Alzheimer disease

scientific article

BDNF Val66Met in preclinical Alzheimer's disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF.

scientific article

BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease

scientific article published on 12 June 2013

Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease ⬇️

scientific article published on October 1, 2012

Bone mineral density, adiposity, and cognitive functions

scientific article

Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults.

scientific article published on 31 March 2016

Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease

scientific article published on 13 March 2013

Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study.

scientific article published on 19 July 2016

Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study

scientific article

Concordance Between Cerebrospinal Fluid Biomarkers with Alzheimer's Disease Pathology Between Three Independent Assay Platforms

scientific article

Concordant peripheral lipidome signatures in two large clinical studies of Alzheimer's disease

scientific article published on 10 November 2020

Effect of APOE Genotype on Amyloid Deposition, Brain Volume, and Memory in Cognitively Normal Older Individuals.

scientific article

Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer's disease: a preliminary study

scientific article

Estimates of age-related memory decline are inflated by unrecognized Alzheimer's disease

scientific article published on 11 June 2018

Examination of the current top candidate genes for AD in a genome-wide association study

scientific article

Expanding the association between the APOE gene and the risk of Alzheimer's disease: possible roles for APOE promoter polymorphisms and alterations in APOE transcription.

scientific article

Fine mapping of the MAPT locus using quantitative trait analysis identifies possible causal variants in Alzheimer's disease

scientific article published on 19 December 2006

Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort

scientific article

Functional effects of genetic polymorphism in inflammatory genes in subjective memory complainers

scientific article published on 18 October 2010

Genetic analysis of MAPT haplotype diversity in frontotemporal dementia

scientific article published on 26 March 2007

Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden.

scientific article published on 26 February 2018

Homocysteine, vitamin B12, and folic acid levels in Alzheimer's disease, mild cognitive impairment, and healthy elderly: baseline characteristics in subjects of the Australian Imaging Biomarker Lifestyle study

scientific article published in January 2011

Increased central adiposity is associated with pro-inflammatory immunoglobulin G N-glycans

scientific article published on 19 October 2018

Increased levels of apolipoprotein E in the frontal cortex of subjects with schizophrenia.

scientific article published in September 2003

Influence of BDNF Val66Met on the relationship between cardiorespiratory fitness and memory in cognitively normal older adults

scientific article published on 09 January 2019

Influence of BDNF Val66Met on the relationship between physical activity and brain volume.

scientific article published on 3 September 2014

Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults.

scientific article published on 29 August 2017

Is cholesterol and amyloid-β stress induced CD147 expression a protective response? Evidence that extracellular cyclophilin a mediated neuroprotection is reliant on CD147.

scientific article

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden

scientific article published in February 2018

Klotho allele status is not associated with Aβ and APOE ε4-related cognitive decline in preclinical Alzheimer's disease

scientific article published on 06 January 2019

Lack of evidence to support the association of polymorphisms within the alpha- and beta-secretase genes (ADAM10/BACE1) with Alzheimer's disease

scientific article published on 3 April 2009

Mediterranean diet adherence and rate of cerebral Aβ-amyloid accumulation: Data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing

article

No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer's disease

scientific article published on 18 April 2009

No association of chromatin-modifying protein 2B with sporadic frontotemporal dementia

scientific article published on 18 September 2006

No association of common VCP variants with sporadic frontotemporal dementia

scientific article published on 5 July 2007

No association of lipase C polymorphisms with Alzheimer's disease

scientific article published on 19 January 2009

Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity.

scientific article

Olfactory discrimination predicts cognitive decline among community-dwelling older adults.

scientific article

Olfactory dysfunction is associated with subjective memory complaints in community-dwelling elderly individuals.

scientific article

Performance on the Cogstate Brief Battery Is Related to Amyloid Levels and Hippocampal Volume in Very Mild Dementia.

scientific article published in September 2016

Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing.

scientific article published on 14 August 2012

Plasma Cortisol, Brain Amyloid-β, and Cognitive Decline in Preclinical Alzheimer's Disease: A 6-Year Prospective Cohort Study

scientific article published on 07 September 2016

Plasma amyloid-beta as a biomarker in Alzheimer's disease: the AIBL study of aging

scientific article

Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging

scientific article published on 22 December 2015

Predicting Alzheimer disease from a blood-based biomarker profile: A 54-month follow-up

scientific article published on 17 August 2016

Relationship Between Amyloid-β Positivity and Progression to Mild Cognitive Impairment or Dementia over 8 Years in Cognitively Normal Older Adults

scientific article published on 01 January 2018

Resistance training enhances delayed memory in healthy middle-aged and older adults: A randomised controlled trial

scientific article published on 27 June 2019

Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture

scientific article published on 23 September 2020

SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease.

scientific article published in September 2012

Self-Reported Physical Activity is Associated with Tau Burden Measured by Positron Emission Tomography

scientific article published on 01 January 2018

Study protocol of the Intense Physical Activity and Cognition study: The effect of high-intensity exercise training on cognitive function in older adults.

scientific article published on 19 October 2017

Subjective memory complaints predict baseline but not future cognitive function over three years: results from the Western Australia Memory Study

article

Superior Memory Reduces 8-year Risk of Mild Cognitive Impairment and Dementia But Not Amyloid β-Associated Cognitive Decline in Older Adults

scientific article published on 01 July 2019

TNF polymorphisms in Alzheimer disease and functional implications on CSF beta-amyloid levels.

scientific article published in July 2005

TNF-Block Genotypes Influence Susceptibility to HIV-Associated Sensory Neuropathy in Indonesians and South Africans

scientific article published on 07 January 2020

The -491AA polymorphism in the APOE gene is associated with increased plasma apoE levels in Alzheimer's disease

scientific article published on 01 March 1999

The APOE ε4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease

scientific article published on 28 April 2017

The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity

scientific article published on 22 January 2016

The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes

scientific article

The Relationship between Sleep Quality and Brain Amyloid Burden

scientific article published on 12 April 2016

The cathepsin D rs17571 polymorphism: effects on CSF tau concentrations in Alzheimer disease

scientific article published in June 2006

The relationship between memory complaints, perceived quality of life and mental health in apolipoprotein Eepsilon4 carriers and non-carriers

scientific article published in January 2009

Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study.

scientific article

Trajectories of irregular word reading ability as a proxy for premorbid intelligence in Alzheimer’s disease, mild cognitive impairment, and healthy aging: A longitudinal study

scientific article published in October 2018

Trajectories of memory decline in preclinical Alzheimer's disease: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of ageing.

scientific article published on 20 December 2014

Unravelling Immunoglobulin G Fc N-Glycosylation: A Dynamic Marker Potentiating Predictive, Preventive and Personalised Medicine

scientific article published on 29 January 2018

Utility of an Alzheimer's Disease Risk-Weighted Polygenic Risk Score for Predicting Rates of Cognitive Decline in Preclinical Alzheimer's Disease: A Prospective Longitudinal Study

scientific article published on 01 January 2018

Validation of a priori candidate Alzheimer's disease SNPs with brain amyloid-beta deposition

scientific article published on 19 November 2019

Variation at the APOE -491 promoter locus is associated with altered brain levels of apolipoprotein E.

scientific article published in January 2002

Visual paired associate learning deficits associated with elevated beta-amyloid in cognitively normal older adults

scientific article published on 01 August 2019

Weak independent association signals between IDE polymorphisms, Alzheimer's disease and cognitive measures.

scientific article published on 3 May 2006

[Frontotemporal lobar degeneration. Part 1: diagnosis and treatment]

scientific article published on 12 March 2009

val158met is not associated with Aβ-amyloid and ε4 related cognitive decline in cognitively normal older adults ⬇️

scientific article published on 02 May 2019

β-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men.

scientific article published on 17 August 2016

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