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List of works by Kiyonao Sada

A novel mitochondrial ubiquitin ligase plays a critical role in mitochondrial dynamics

scientific article

A novel phenoxazine derivative suppresses surface IgM expression in DT40 B cell line

scientific article published on November 2002

Activation of Syk protein tyrosine kinase in response to osmotic stress requires interaction with p21-activated protein kinase Pak2/gamma-PAK.

scientific article

Activation of p72syk by Thrombin in a Cell-Free System

article published in 1994

Adaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase

scientific article

Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells

scientific article published on 13 November 2011

CPTK71, a cytosolic protein-tyrosine kinase previously purified from bovine platelets, is identical with p72syk

scientific article published on May 1994

Characterization of partially purified cytosolic protein-tyrosine kinase from porcine spleen ⬇️

scientific article published on May 16, 1988

Cyclic AMP-Elevating Agents Negatively Regulate the Activation of p72Syk in N-Formyl-methionyl-leucyl-phenylalanine Receptor Signaling

scientific article published on 01 July 1995

Dectin-1-mediated signaling leads to characteristic gene expressions and cytokine secretion via spleen tyrosine kinase (Syk) in rat mast cells

scientific article

Enhancement of B-cell receptor signaling by a point mutation of adaptor protein 3BP2 identified in human inherited disease cherubism.

scientific article published on 28 July 2011

HCV NS5A protein containing potential ligands for both Src homology 2 and 3 domains enhances autophosphorylation of Src family kinase Fyn in B cells

scientific article published on 16 October 2012

HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters

scientific article published on 27 February 2009

Helicobacter pylori CagA containing ITAM-like sequences localized to lipid rafts negatively regulates VacA-induced signaling in vivo

scientific article published on February 2003

Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk.

scientific article

Inhibition of hepatitis C virus replication through adenosine monophosphate-activated protein kinase-dependent and -independent pathways

scientific article

Inhibition of measles virus and subacute sclerosing panencephalitis virus by RNA interference

scientific article published on 13 February 2006

Inhibitory effect of açaí (Euterpe oleracea Mart.) pulp on IgE-mediated mast cell activation

scientific article published on 4 May 2011

Interleukin 2 mediates p72 syk activation in peripheral blood lymphocytes

scientific article published on 01 May 1994

Involvement of Protein-Tyrosine Kinase p72syk in Collagen-Induced Signal Transduction in Platelets

scientific article published on 01 November 1994

Involvement of reactive oxygen intermediates in lectin-induced protein-tyrosine phosphorylation of Syk in THP-1 cells

scientific article published on May 1998

NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner

scientific article

Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b

scientific journal article

Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation

scientific journal article

Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis

scientific article published on July 2006

Oxaliplatin enhances TRAIL-induced apoptosis in gastric cancer cells by CBL-regulated death receptor redistribution in lipid rafts

scientific article

Platelet-activating factor stimulates calcium-dependent activation of protein-tyrosine kinase Syk in a human B cell line

scientific article published on October 1997

Point mutations of 3BP2 identified in human-inherited disease cherubism result in the loss of function

scientific article

Possible role of Na+ influx in phorbol ester-induced down-regulation of protein kinase C in HL60 cells

scientific article published on 01 August 1993

Protein tyrosine kinase Lyn mediates apoptosis induced by topoisomerase II inhibitors in DT40 cells

scientific article published on September 1999

Protein tyrosine kinase Syk in mast cell signaling

scientific article

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

scientific journal article

Protein-tyrosine kinases and adaptor proteins in FcepsilonRI-mediated signaling in mast cells

scientific article

Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells

scientific article

Relocation of Syk protein-tyrosine kinase to the actin filament network and subsequent association with Fak

scientific article

Reversal of P-glycoprotein-mediated multi-drug resistance by the E3 ubiquitin ligase Cbl-b in human gastric adenocarcinoma cells

scientific article published on June 2009

Role of protein-tyrosine kinase syk in oxidative stress signaling in B cells

scientific article

Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

scientific article

SH2 domain-mediated targeting, but not localization, of Syk in the plasma membrane is critical for FcepsilonRI signaling

scientific article

Selective inhibition of Fcepsilon RI-mediated mast cell activation by a truncated variant of Cbl-b related to the rat model of type 1 diabetes mellitus.

scientific article published in June 2005

Sendai virus C protein plays a role in restricting PKR activation by limiting the generation of intracellular double-stranded RNA.

scientific article published on 06 August 2008

Signal transduction through mu kappa B-cell receptors expressed on pre-B cells is different from that through B-cell receptors on mature B cells

scientific article published on August 1996

Single-point mutations of hepatitis C virus NS3 that impair p53 interaction and anti-apoptotic activity of NS3.

scientific article

Syk Is Required for p38 Activation and G2/M Arrest in B Cells Exposed to Oxidative Stress

scholarly article by Jinsong He published in June 2002

The phenoxazine derivative Phx-1 suppresses IgE-mediated degranulation in rat basophilic leukemia RBL-2H3 cells

scientific article published on March 2004

Translocation, activation and association of protein-tyrosine kinase (p72syk) with phosphatidylinositol 3-kinase are early events during platelet activation

scientific article

Tyrosine phosphorylation of 3BP2 is indispensable for the interaction with VAV3 in chicken DT40 cells

scientific article published on 6 January 2014

Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT

scientific article

Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor

scientific article

Ubiquitin ligase Cbl-b sensitizes leukemia and gastric cancer cells to anthracyclines by activating the mitochondrial pathway and modulating Akt and ERK survival signals

scientific article

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