List of works - William R. Lagor

Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia

scientific article published on 14 November 2012

Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism

scientific article published on January 2013

Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism

scientific article

Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure

scientific article

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

scientific article

Diabetes alters the occupancy of the hepatic 3-hydroxy-3-methylglutaryl-CoA reductase promoter

scientific article published on 26 August 2005

Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.

scientific article published on 10 January 2014

Identification of insulin-responsive regions in the HMG-CoA reductase promoter

scientific article published on June 2004

LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study

scientific article published in 2022

Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

scientific article

Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.

scientific article

Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice

scientific article published on 03 February 2011

Phospholipidation of HDL--how much is too much?

scientific article published on 15 November 2010

Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.

scientific article published on 18 December 2015

Targeting adipose tissue via systemic gene therapy

scientific article

Technological advances in the study of HLA-DRA promoter regulation: extending the functions of CIITA, Oct-1, Rb, and RFX.

scientific article published on March 2009

Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter.

scientific article

Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice

scientific article

List of works by William R. Lagor

Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia

Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism

Ca2+ Binding/Permeation via Calcium Channel, CaV1.1, Regulates the Intracellular Distribution of the Fatty Acid Transport Protein, CD36, and Fatty Acid Metabolism

Deletion of murine Arv1 results in a lean phenotype with increased energy expenditure

Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model

Diabetes alters the occupancy of the hepatic 3-hydroxy-3-methylglutaryl-CoA reductase promoter

Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.

Identification of insulin-responsive regions in the HMG-CoA reductase promoter

LPA disruption with AAV-CRISPR potently lowers plasma apo(a) in transgenic mouse model: A proof-of-concept study

Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species.

Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.

Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice

Phospholipidation of HDL--how much is too much?

Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.

Targeting adipose tissue via systemic gene therapy

Technological advances in the study of HLA-DRA promoter regulation: extending the functions of CIITA, Oct-1, Rb, and RFX.

Thyroid hormone enhances the ability of serum to accept cellular cholesterol via the ABCA1 transporter.

Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice