List of works - Akihiko Nishikimi

A reducing and denaturing step maximizes the immunoprecipitations of m-calpain and I-2(PP2A)/SET: an approach toward antibodies that do not work well in immunoprecipitation

scientific article published on 18 March 2006

ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.

scientific article

Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2.

scientific article

Collagen-derived peptides modulate CD4+ T-cell differentiation and suppress allergic responses in mice

scientific article published in February 2018

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

scientific article published on 9 September 2010

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

scientific article

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

scientific article

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

scientific article

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

scientific article

Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells

scientific article

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

scientific article

Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis.

scientific article

Immune regulatory functions of DOCK family proteins in health and disease

scientific article published on 02 August 2013

Inhibitory effect of phosphate on in vitro development of 2-cell rat embryos is overcome by a factor(s) in oviductal extracts

scientific article published in November 1999

Involvement of IL-1 family proteins in p38 linked cellular senescence of mouse embryonic fibroblasts

scientific article published on 01 September 2004

Involvement of glycolytic metabolism in developmental inhibition of rat two-cell embryos by phosphate

scientific article published on 01 December 2000

Next-generation sequencing coupled with a cell-free display technology for high-throughput production of reliable interactome data

scientific article

Nuclear translocation of nuclear factor kappa B in early 1-cell mouse embryos

scientific article published in June 1999

Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.

scientific article published on 18 April 2016

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation

scientific article published on 29 January 2013

Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53.

scientific article published on June 2004

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.

scientific article

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

scientific article

Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.

scientific article

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

scientific article

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.

scientific article published on 2 September 2007

The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation

scientific article

The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway

scientific article published on 25 July 2013

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.

scientific article

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes

scientific article (publication date: 14 February 2005)

cDNA cloning of bovine midkine and production of the recombinant protein, which affects in vitro maturation of bovine oocytes

scientific article published on September 2000

List of works by Akihiko Nishikimi

A reducing and denaturing step maximizes the immunoprecipitations of m-calpain and I-2(PP2A)/SET: an approach toward antibodies that do not work well in immunoprecipitation

ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.

Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK2.

Collagen-derived peptides modulate CD4+ T-cell differentiation and suppress allergic responses in mice

DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4.

DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation

DOCK2 is a Rac activator that regulates motility and polarity during neutrophil chemotaxis

DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

Differential requirement for DOCK2 in migration of plasmacytoid dendritic cells versus myeloid dendritic cells

Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration.

Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis.

Immune regulatory functions of DOCK family proteins in health and disease

Inhibitory effect of phosphate on in vitro development of 2-cell rat embryos is overcome by a factor(s) in oviductal extracts

Involvement of IL-1 family proteins in p38 linked cellular senescence of mouse embryonic fibroblasts

Involvement of glycolytic metabolism in developmental inhibition of rat two-cell embryos by phosphate

Next-generation sequencing coupled with a cell-free display technology for high-throughput production of reliable interactome data

Nuclear translocation of nuclear factor kappa B in early 1-cell mouse embryos

Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.

Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation

Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53.

Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation.

Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.

Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.

The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation

The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway

Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes

cDNA cloning of bovine midkine and production of the recombinant protein, which affects in vitro maturation of bovine oocytes