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List of works by Martin D. Brand

4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production

scientific article published on 01 January 2007

70 Determination of the H+/site and Ca2+/site ratios of mitochondrial electron transport

scientific article published on January 1, 1979

A mitochondrial uncoupling artifact can be caused by expression of uncoupling protein 1 in yeast

scientific article published in June 2001

A prototypical small-molecule modulator uncouples mitochondria in response to endogenous hydrogen peroxide production

scientific article published on 02 May 2013

A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.

scientific article

A refined analysis of superoxide production by mitochondrial sn-glycerol 3-phosphate dehydrogenase.

scientific article

A signalling role for 4-hydroxy-2-nonenal in regulation of mitochondrial uncoupling.

scientific article published on August 2003

A top-down control analysis in isolated rat liver mitochondria: can the 3-hydroxy-3-methylglutaryl-CoA pathway be rate-controlling for ketogenesis?

scientific article published in February 1993

AMP decreases the efficiency of skeletal-muscle mitochondria

scientific article published on October 2000

Altered relationship between protonmotive force and respiration rate in non-phosphorylating liver mitochondria isolated from rats of different thyroid hormone status

scientific article published on 01 December 1988

Analysing microarray data using modular regulation analysis.

scientific article

Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory

scientific article published on 01 March 1990

Apoptosis and the laws of thermodynamics

scientific article published on 01 October 2000

Artifactual uncoupling by uncoupling protein 3 in yeast mitochondria at the concentrations found in mouse and rat skeletal-muscle mitochondria

scientific article

Assessing mitochondrial dysfunction in cells.

scientific article

Biomarkers of aging in Drosophila

scientific article published on 29 March 2010

Caged mitochondrial uncouplers that are released in response to hydrogen peroxide.

scientific article

Changes in the hepatic mitochondrial respiratory system in the transition from weaning to adulthood in rats

scientific article published on 01 April 1998

Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat

scientific article published on 01 December 1994

Characteristics of the turnover of uncoupling protein 3 by the ubiquitin proteasome system in isolated mitochondria

scientific article published on 28 July 2011

Characterization of betaine efflux from rat liver mitochondria

scientific journal article

Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo

scientific article

Chemical Modification of the Mitochodrial bc1 by N,N' -Dicyclohexylcarbodiimide Inhibits Proton Translocation ⬇️

scientific article published on May 16, 1983

Coenzyme Q induces GDP-sensitive proton conductance in kidney mitochondria

scientific article published in November 2001

Cold-induced alterations of phospholipid fatty acyl composition in brown adipose tissue mitochondria are independent of uncoupling protein-1

article

Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium

scientific article (publication date: 2012)

ConA induced changes in energy metabolism of rat thymocytes

scientific article published in October 1992

ConA induced changes in energy metabolism of rat thymocytes

scientific article published on 01 April 1992

Control analysis of DNA microarray expression data.

scientific article

Control of electron flux through the respiratory chain in mitochondria and cells

scientific article published on May 1987

Control of hepatic mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase during the foetal/neonatal transition, suckling and weaning in the rat

scientific article published on 01 January 1991

Control of respiration and oxidative phosphorylation in isolated rat liver cells

scientific article published on 01 September 1990

Degradation of an intramitochondrial protein by the cytosolic proteasome

scientific article

Degradation of an intramitochondrial protein by the cytosolic proteasome.

scientific article

Dependence of brown adipose tissue function on CD36-mediated coenzyme Q uptake

scientific article

Determining Maximum Glycolytic Capacity Using Extracellular Flux Measurements

scientific article

Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport

scientific article published on 18 March 2008

Dissociation of superoxide production by mitochondrial complex I from NAD(P)H redox state

scientific article published on 28 April 2008

Does any yeast mitochondrial carrier have a native uncoupling protein function?

scientific article

Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells

scientific journal article

Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2. ⬇️

scientific article published on 17 June 2009

Effects of cadmium on the control and internal regulation of oxidative phosphorylation in potato tuber mitochondria

scientific article published on 01 November 1994

Effects of glucagon and Na+ on the control of extramitochondrial free Ca2+ concentration by mitochondrial from liver and heart

scientific article published on 01 February 1980

Effects of magnesium and nucleotides on the proton conductance of rat skeletal-muscle mitochondria

scientific article published on May 2000

Effects of methylprednisolone on the energy metabolism of quiescent and conA-stimulated thymocytes of the rat ⬇️

scientific article published on February 1, 1993

Effects of the mitogen concanavalin A on pathways of thymocyte energy metabolism.

scientific article

Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T.

scientific article published on 26 January 2008

Exploiting Mitochondria In Vivo as Chemical Reaction Chambers Dependent on Membrane Potential

scientific article published on 01 March 2016

Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan

scientific article published on May 2009

Functional characterisation of UCP1 in the common carp: uncoupling activity in liver mitochondria and cold-induced expression in the brain

scientific article published on 19 June 2007

Generation of superoxide and hydrogen peroxide by side reactions of mitochondrial 2-oxoacid dehydrogenase complexes in isolation and in cells

scientific article published on 27 June 2017

High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria

scientific article

Hydroxynonenal and uncoupling proteins: a model for protection against oxidative damage.

scientific article

Hypothyroidism in rats decreases mitochondrial inner membrane cation permeability

scientific article

Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening

scientific article

Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I).

scientific article

Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes

scientific article published on 01 December 1999

Intrinsic Bioenergetic Properties and Stress Sensitivity of Dopaminergic Synaptosomes ⬇️

scientific article published on March 23, 2011

Lack of correlation between mitochondrial reactive oxygen species production and life span in Drosophila

scientific article published in June 2004

Leptin-mediated changes in hepatic mitochondrial metabolism, structure, and protein levels

scholarly article

Light changes the membrane potential and ion balances of retinal rod disks

scientific article published on 01 March 1985

Localisation of the sites of action of cadmium on oxidative phosphorylation in potato tuber mitochondria using top-down elasticity analysis

scientific article published on 01 November 1994

Low complex I content explains the low hydrogen peroxide production rate of heart mitochondria from the long-lived pigeon, Columba livia

scientific article published on 25 November 2009

Low rates of hydrogen peroxide production by isolated heart mitochondria associate with long maximum lifespan in vertebrate homeotherms

scientific article published on 27 June 2007

Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate.

scientific article published on 12 December 2015

Measurement of Proton Leak and Electron Leak in Isolated Mitochondria ⬇️

scientific article published on 01 January 2012

Measuring mitochondrial bioenergetics in INS-1E insulinoma cells

scientific article

Measuring mitochondrial uncoupling protein-2 level and activity in insulinoma cells.

scientific article published on January 2013

Membrane-potential-dependent changes in the stoichiometry of charge translocation by the mitochondrial electron transport chain

scientific article published on 01 May 1988

Metabolic downregulation and inhibition of carbohydrate catabolism during diapause in embryos of Artemia franciscana.

scientific article

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean

scientific article

Mitochondria as ATP consumers: cellular treason in anoxia.

scientific article published on July 2000

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions ⬇️

scientific article published on June 11, 2012

Mitochondrial bioenergetics and neuronal survival modelled in primary neuronal culture and isolated nerve terminals

scientific article

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling.

scientific article published on 13 April 2016

Mitochondrial proton leak kinetics and relationship with feed efficiency within a single genetic line of male broilers.

scientific article published in August 2009

Mitochondrial uncouplers with an extraordinary dynamic range

scientific article published in October 2007

Mitochondrial uncoupling and lifespan.

scientific article

Mitochondrial uncoupling protein 2 in pancreatic β-cells.

scientific article published on October 2010

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

scientific journal article

Molecular properties of purified human uncoupling protein 2 refolded from bacterial inclusion bodies

scientific article published in October 2003

No Consistent Bioenergetic Defects in Presynaptic Nerve Terminals Isolated from Mouse Models of Alzheimer's Disease ⬇️

scientific article published on November 21, 2012

Nonsteroidal antiinflammatory drugs and a selective cyclooxygenase 2 inhibitor uncouple mitochondria in intact cells

scientific article published in May 2003

Not all mitochondrial carrier proteins support permeability transition pore formation: no involvement of uncoupling protein 1.

scientific article

Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.

scientific article

Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies

scientific article published on September 2002

Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

scientific article published on December 2002

Permeability of mitochondria from rat brain and rat liver to GABA.

scientific article published in January 1974

Permeability of mitochondria to neutral amino acids ⬇️

scientific article published on August 15, 1973

Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

scientific article

Physiological levels of mammalian uncoupling protein 2 do not uncouple yeast mitochondria

scientific article

Plasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics

scientific article

Plasticity of oxidative metabolism in variable climates: molecular mechanisms.

scientific article published on September 2010

Positive Feedback Amplifies the Response of Mitochondrial Membrane Potential to Glucose Concentration in Clonal Pancreatic Beta Cells

scientific article published on 20 October 2016

Production of endogenous matrix superoxide from mitochondrial complex I leads to activation of uncoupling protein 3.

scientific article

Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions.

scientific article published on 24 August 2017

Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria

scientific article published on 16 April 2014

Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex.

scientific article published on 18 December 2015

Proportional activation coefficients during stimulation of oxidative phosphorylation by lactate and pyruvate or by vasopressin

scientific article published on 01 May 1995

Proton conductance and fatty acyl composition of liver mitochondria correlates with body mass in birds

scientific article published in December 2003

Proton leak and control of oxidative phosphorylation in perfused, resting rat skeletal muscle

scientific article published on 01 August 1996

Proton leak in hepatocytes and liver mitochondria from archosaurs (crocodiles) and allometric relationships for ectotherms.

scientific article published on 4 May 2002

Quantifying elasticity analysis: how external effectors cause changes to metabolic systems

scientific article published in February 1999

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements

scientific article published on 7 March 2017

Quantitative determination of the regulation of oxidative phosphorylation by cadmium in potato tuber mitochondria

scientific article published on 01 November 1994

Quantitative measurement of mitochondrial membrane potential in cultured cells: calcium-induced de- and hyperpolarization of neuronal mitochondria

scientific article published on 10 April 2012

Quantitative microplate-based respirometry with correction for oxygen diffusion

scientific article published in August 2009

Reactive oxygen species production by mitochondria.

scientific article published on January 2009

Research on mitochondria and aging, 2006-2007.

scientific article published on August 2007

Respiration rate of hepatocytes varies with body mass in birds

scientific article published on June 2004

Riding the tiger - physiological and pathological effects of superoxide and hydrogen peroxide generated in the mitochondrial matrix

scientific article published on 04 November 2020

Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction.

scientific article

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

scientific article published on 23 May 2013

Sites of superoxide and hydrogen peroxide production by muscle mitochondria assessed ex vivo under conditions mimicking rest and exercise

scientific article

Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria.

scientific article published on 11 April 2013

Size changes of phosphodiesterase in bovine rod outer segments on illumination

scientific article published in March 1983

Sources of superoxide/H2O2 during mitochondrial proline oxidation

scientific article

Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells.

scientific article published on 15 October 2015

Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant

scientific article

Stimulation of the electron transport chain in mitochondria isolated from rats treated with mannoheptulose or glucagon

scientific article published on 01 December 1990

Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria

scientific article published in January 2006

Structure and function of mitochondria in hepatopancreas cells from metabolically depressed snails

scientific article published in March 2002

Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus).

scientific article published on December 2003

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants

scientific journal article

Superoxide activates mitochondrial uncoupling proteins ⬇️

scientific article (publication date: 3 January 2002)

Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.

scientific article published on 12 September 2003

Superoxide and hydrogen peroxide production by Drosophila mitochondria

scientific article published in October 2003

Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein

scientific article published on 2 April 2003

Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

scientific article published on 21 September 2016

Suppressors of superoxide production from mitochondrial complex III

scientific article

Target size analysis of rhodopsin in retinal rod disk membranes.

scientific article

Targeting dinitrophenol to mitochondria: limitations to the development of a self-limiting mitochondrial protonophore

scientific article

The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I

scientific article published on 10 February 2014

The Basal Proton Conductance of Skeletal Muscle Mitochondria from Transgenic Mice Overexpressing or Lacking Uncoupling Protein-3 ⬇️

scientific article published on November 13, 2001

The basal proton conductance of mitochondria depends on adenine nucleotide translocase content

scientific article published on December 2005

The causes and functions of mitochondrial proton leak

scientific article published on August 1994

The contribution of the leak of protons across the mitochondrial inner membrane to standard metabolic rate

scientific article published on July 1990

The contributions of respiration and glycolysis to extracellular acid production

scientific article published on 27 October 2014

The efficiency and plasticity of mitochondrial energy transduction.

scientific article

The efficiency of cellular energy transduction and its implications for obesity

scientific article published on January 2008

The mechanism of the increase in mitochondrial proton permeability induced by thyroid hormones

scientific article

The physiological significance of mitochondrial proton leak in animal cells and tissues

scientific article published on February 1997

The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: comparison with isolated mitochondria

scientific article published in January 1997

The proton permeability of liposomes made from mitochondrial inner membrane phospholipids: no effect of fatty acid composition

scientific article published on 01 December 1997

The proton permeability of the inner membrane of liver mitochondria from ectothermic and endothermic vertebrates and from obese rats: correlations with standard metabolic rate and phospholipid fatty acid composition.

scientific article published in February 1998

The reactions catalysed by the mitochondrial uncoupling proteins UCP2 and UCP3.

scientific article

The regulation and turnover of mitochondrial uncoupling proteins.

scientific article

The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis

scientific article published on 01 November 1999

The role of mitochondrial function and cellular bioenergetics in ageing and disease

scientific article

The role of mitochondrially derived ATP in synaptic vesicle recycling

scientific article

The stoichiometry of charge translocation by cytochrome oxidase and the cytochrome bc1 complex of mitochondria at high membrane potential

scientific article published on 01 May 1988

The sum of flux control coefficients in the electron-transport chain of mitochondria

scientific article published on 01 December 1994

The topology of superoxide production by complex III and glycerol 3-phosphate dehydrogenase in Drosophila mitochondria

scientific article

Therapeutically targeting lymphocyte energy metabolism by high-dose glucocorticoids

scientific article published in March 2000

Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex

scientific article published on January 1985

Thermodynamic limits to the stoichiometry of H+ pumping by mitochondrial cytochrome oxidase.

scientific article published in July 1985

Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes

scientific article published on 01 August 1999

Top-down control analysis of systems with more than one common intermediate.

scientific article published in August 1995

Topology of superoxide production from different sites in the mitochondrial electron transport chain

scientific article (publication date: 22 November 2002)

Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

scientific article published in July 2005

UCP2 and UCP3 rise in starved rat skeletal muscle but mitochondrial proton conductance is unchanged

scientific article published on December 1999

UCPs--unlikely calcium porters.

scientific article published in November 2008

Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria

scientific article published on April 2004

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

scientific article

Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria

scientific article published in September 2005

Uncoupling protein and ATP/ADP carrier increase mitochondrial proton conductance after cold adaptation of king penguins

scientific article

Uncoupling protein-1 (UCP1) contributes to the basal proton conductance of brown adipose tissue mitochondria.

scientific article published on 25 August 2009

Uncoupling proteins: the unravelling of obesity? Increased understanding of mechanisms may lead, in time, to better drugs

scientific article published on December 1998

Unequal charge separation by different coupling spans of the mitochondrial electron transport chain

scientific article published in November 1978

Valinomycin can depolarize mitochondria in intact lymphocytes without increasing plasma membrane potassium fluxes

scientific article published on 01 December 1982

Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent

scientific article published on January 2011

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