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List of works by Johannes Winkler

2'-O-Lysylaminohexyl oligonucleotides: modifications for antisense and siRNA.

scientific article published on January 2008

A novel concept for ligand attachment to oligonucleotides via a 2'-succinyl linker.

scientific article published on 2 February 2004

A proteomic study reveals unspecific apoptosis induction and reduction of glycolytic enzymes by the phosphorothioate antisense oligonucleotide oblimersen in human melanoma cells.

scientific article

Blood-brain barrier cell line PBMEC/C1-2 possesses functionally active P-glycoprotein.

scientific article

Cardiac Stem Cell-based Regenerative Therapy for the Ischemic Injured Heart — a Short Update 2017

Concise postsynthetic preparation of oligonucleotide-oligopeptide conjugates through facile disulfide bond formation.

scientific article published on 18 September 2015

Effects of NMDA receptor modulators on a blood-brain barrier in vitro model.

scientific article published on 13 April 2011

EpCAM-targeted delivery of nanocomplexed siRNA to tumor cells with designed ankyrin repeat proteins

scientific article

Extrahepatic Targeting of Oligonucleotides with Receptor-Binding Non-Immunoglobulin Scaffold Proteins

scientific article published on 07 May 2018

Fluorescence- and computed tomography for assessing the biodistribution of siRNA after intratracheal application in mice

scientific article published on 14 February 2017

Fragment-based solid-phase assembly of oligonucleotide conjugates with peptide and polyethylene glycol ligands

scientific article published on 3 May 2016

Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides.

scientific article published on 02 March 2013

Inhibition of CD34+ cell migration by matrix metalloproteinase-2 during acute myocardial ischemia, counteracted by ischemic preconditioning

scientific article

Intrinsic remote conditioning of the myocardium as a comprehensive cardiac response to ischemia and reperfusion

scientific article published on 12 June 2017

Isolation of eudesmanes from Pluchea odorata and evaluation of their effects on cancer cell growth and tumor invasiveness in vitro.

scientific article

Long-term regulation of gene expression in muscle cells by systemically delivered siRNA.

scientific article

Matrix Metalloproteinase-2 Impairs Homing of Intracoronary Delivered Mesenchymal Stem Cells in a Porcine Reperfused Myocardial Infarction: Comparison With Intramyocardial Cell Delivery.

scientific article

Molecular Imaging of Angiogenesis in Cardiac Regeneration

scientific article

Myocardial fibrosis: biomedical research from bench to bedside.

scientific article

Off-target effects related to the phosphorothioate modification of nucleic acids.

scientific article published on August 2010

Oligonucleotide charge reversal: 2'-O-lysylaminohexyl modified oligonucleotides

scientific article published in January 2007

Oligonucleotide conjugates for therapeutic applications.

scientific article published on July 2013

Oligonucleotide-polyamine conjugates: influence of length and position of 2'-attached polyamines on duplex stability and antisense effect

scientific article

Oligonucleotides conjugated to short lysine chains

scientific article

Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension.

scientific article published on 6 October 2017

Preclinical Studies of Stem Cell Therapy for Heart Disease

scientific article published on 01 March 2018

Sequential activation of different pathway networks in ischemia-affected and non-affected myocardium, inducing intrinsic remote conditioning to prevent left ventricular remodeling

scientific article published on 07 March 2017

Therapeutic oligonucleotides with polyethylene glycol modifications.

scientific article published on 29 September 2015

Triterpenoic Acids from Apple Pomace Enhance the Activity of the Endothelial Nitric Oxide Synthase (eNOS).

scientific article published on 18 December 2015

miRNA-based therapies: strategies and delivery platforms for oligonucleotide and non-oligonucleotide agents

scientific article

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