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List of works by Jens M. Hohlfeld

A dual center study to compare breath volatile organic compounds from smokers and non-smokers with and without COPD.

scientific article

Aerosolized surfactant inhibits acetylcholine-induced airway obstruction in rats

scientific article published in October 1997

Allergen challenge increases anandamide in bronchoalveolar fluid of patients with allergic asthma

scientific article published on 29 June 2011

Allergen exposure chambers: harmonizing current concepts and projecting the needs for the future - an EAACI Position Paper.

scientific article published on 25 January 2017

Allergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein D

scientific article published on 22 June 2010

Allergen-induced asthmatic responses modified by a GATA3-specific DNAzyme

scientific article

Anti-allergic drug testing in an environmental challenge chamber is suitable both in and out of the relevant pollen season

scientific article published on 05 February 2011

Breath profiles by electronic nose correlate with systemic markers but not ozone response

scientific article published on 24 March 2011

Breath volatile organic compounds and inflammatory markers in adult asthma patients - negative results from the ALLIANCE cohort

scientific article published on 02 October 2020

Breath volatile organic compounds of lung transplant recipients with and without chronic lung allograft dysfunction.

scientific article

Bronchial epithelial cells as a new source for differential transcriptome analysis after lung transplantation.

scientific article

Cardiac safety of tiotropium in patients with COPD: a combined analysis of Holter-ECG data from four randomised clinical trials

scientific article

Cell counting in human endobronchial biopsies--disagreement of 2D versus 3D morphometry

scientific article

Changes of breath volatile organic compounds in healthy volunteers following segmental and inhalation endotoxin challenge

scientific article published in 2022

Characterization of exhaled particles from the healthy human lung--a systematic analysis in relation to pulmonary function variables

scientific article

Characterization of exhaled particles from the human lungs in airway obstruction.

scientific article

Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.

scientific article published on 22 May 2015

Comprehensive characterisation of pulmonary and serum surfactant protein D in COPD.

scientific article

Constant-load exercise decreases the serum concentration of myeloperoxidase in healthy smokers and smokers with COPD

scientific article published on 21 July 2015

Correlation of donor leukocyte chimerism with pulmonary allograft survival after immunosuppressive drug withdrawal in a porcine model

scientific article published in May 2009

Detection of air trapping in chronic obstructive pulmonary disease by low frequency ultrasound ⬇️

scientific article published on March 16, 2012

Development and validation of a cough and sputum assessment questionnaire.

scientific article published on 27 July 2008

Diagnostic value of outcome measures following allergen exposure in an environmental challenge chamber compared with natural conditions

scientific article published on 13 April 2010

Divergence in urinary 8-iso-PGF(2alpha) (iPF(2alpha)-III, 15-F(2t)-IsoP) levels from gas chromatography-tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-P

scientific article published in September 2003

Effect of acute ozone induced airway inflammation on human sympathetic nerve traffic: a randomized, placebo controlled, crossover study

scientific article

Effect of anti-nerve growth factor on early and late airway responses in allergic rats

scientific article published in September 2003

Effect of loteprednol etabonate nasal spray suspension on seasonal allergic rhinitis assessed by allergen challenge in an environmental exposure unit

scientific article

Effects of exogenous surfactant instillation in clinical lung transplantation: a prospective, randomized trial

scientific article published on June 2007

Effects of keratinocyte growth factor on intra-alveolar surfactant fixed in situ: Quantitative ultrastructural and immunoelectron microscopic analysis

scientific article published on 01 August 2007

Effects of ultrafine particles on the allergic inflammation in the lung of asthmatics: results of a double-blinded randomized cross-over clinical pilot study

scientific article

Efficacy and safety of a novel nasal steroid, S0597, in patients with seasonal allergic rhinitis

scientific article published on 10 August 2015

Efficacy and safety of inhaled calcium lactate PUR118 in the ozone challenge model--a clinical trial.

scientific article published on 12 August 2015

Efficacy of the oral chemoattractant receptor homologous molecule on TH2 cells antagonist BI 671800 in patients with seasonal allergic rhinitis

scientific article

Elastase-induced lung emphysema in rats is not reduced by hematopoietic growth factors when applied preventionally

scientific article published on 25 April 2008

Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography

scientific article published on 26 May 2016

Endotoxin augments myeloid dendritic cell influx into the airways in patients with allergic asthma

scientific article published on 3 April 2008

Enhanced expression of fas ligand (CD95L) on T cells after segmental allergen provocation in asthma

scientific article published on 01 April 1999

Eosinophil cationic protein alters pulmonary surfactant structure and function in asthma

scientific article published in March 2004

Exacerbation of atopic dermatitis on grass pollen exposure in an environmental challenge chamber

scientific article published in June 2015

Exhaled breath condensate: methodological recommendations and unresolved questions.

scientific article

Exogenous surfactant improves survival and surfactant function in ischaemia-reperfusion injury in minipigs.

scientific article

Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers

scientific article

Gene targeting of the cysteine peptidase cathepsin H impairs lung surfactant in mice

scientific article

Glutathione improves the function of porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution

scientific article

Human eosinophil granulocytes do not express the enzyme arginase

scientific article published on 3 March 2010

Identification and quantification of basophils in the airways of asthmatics following segmental allergen challenge

scientific article published on 14 April 2014

Iloprost to improve surfactant function in porcine pulmonary grafts stored for twenty-four hours in low-potassium dextran solution

scientific article published in January 2005

Impact of a Met(11)Thr single nucleotide polymorphism of surfactant protein D on allergic airway inflammation in a murine asthma model

scientific article published on 01 April 2014

Impact of endobronchial allergen provocation on macrophage phenotype in asthmatics

scientific article

In vivo inhibition of epidermal growth factor receptor autophosphorylation prevents receptor internalization.

scientific article published on 18 September 2010

In-situ topical cooling of lung grafts: early graft function and surfactant analysis in a porcine single lung transplant model

scientific article published in September 2003

Independent information of nonspecific biomarkers in exhaled breath condensate

scientific article published on 12 August 2010

Influence of plasma and inflammatory proteins on the ultrastructure of exogenous surfactant

scientific article published on 01 January 2004

Inter- and intrasubject variability of the inflammatory response to segmental endotoxin challenge in healthy volunteers.

scientific article

Interaction of nanoparticles with the pulmonary surfactant system.

scientific article published on July 2009

Keratinocyte growth factor prevents intra-alveolar oedema in experimental lung isografts

scientific article published on 10 October 2007

LPS-induced lung inflammation in marmoset monkeys - an acute model for anti-inflammatory drug testing

scientific article

Local nitric oxide levels reflect the degree of allergic airway inflammation after segmental allergen challenge in asthmatics

scientific article

Local release of eosinophil peroxidase following segmental allergen provocation in asthma

scientific article published on 01 March 2003

Local treatment with BPPcysMPEG reduces allergic airway inflammation in sensitized mice

scientific article published on 08 May 2010

Low-dose endotoxin inhalation in healthy volunteers--a challenge model for early clinical drug development.

scientific article

Measurement of exhaled volatile organic compounds from patients with chronic obstructive pulmonary disease (COPD) using closed gas loop GC-IMS and GC-APCI-MS.

scientific article published on 8 April 2016

Metal-rich ambient particles (particulate matter 2.5) cause airway inflammation in healthy subjects

scientific article published on 30 June 2004

Natural innate cytokine response to immunomodulators and adjuvants in human precision-cut lung slices.

scientific article published on 29 April 2010

Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: a proof of concept study

scientific article published on 08 September 2014

On the importance of the use of proper approaches for comparison of analytical methods for serum nitrate and for evaluation of reference concentrations.

scientific article

Pharmacokinetics and pharmacodynamics of tiotropium solution and tiotropium powder in chronic obstructive pulmonary disease

scientific article

Phase-contrast MRI for detection of mild systemic hemodynamic response after segmental allergen challenge in asthmatic patients

scientific article published in August 2014

Pneumococcal vaccination: conjugated vaccine induces herd immunity and reduces antibiotic resistance

scientific article published in February 2008

Pollen starch granules in bronchial inflammation

scientific article published on 18 July 2012

Potential prognostic value of biomarkers in lavage, sputum and serum in a five year clinical follow-up of smokers with and without COPD

scientific article

Preoperative low-dose irradiation promotes long-term allograft acceptance and induces regulatory T cells in a porcine model of pulmonary transplantation.

scientific article

Pulmonary preservation with Bretscheider's HTK and Celsior solution in minipigs

scientific article published in June 2002

Pulmonary preservation with LPD and celsior solution in porcine lung transplantation after 24 h of cold ischemia

scientific article

Quantification of pulmonary inflammation after segmental allergen challenge using turbo-inversion recovery-magnitude magnetic resonance imaging.

scientific article

Randomized immunotherapy trial in dual-allergic patients using "active allergen placebo" as control

scientific article published on 28 May 2019

Rating sputum cell quality in clinical trials for asthma and COPD treatment

scientific article published on 08 January 2019

Regulation of GATA-3, c-maf and T-bet mRNA expression in bronchoalveolar lavage cells and bronchial biopsies after segmental allergen challenge.

scientific article

Repeatability of and relationship between potential COPD biomarkers in bronchoalveolar lavage, bronchial biopsies, serum, and induced sputum

scientific article

Repetitive measurements of pulmonary mechanics to inhaled cholinergic challenge in spontaneously breathing mice.

scientific article published on 30 April 2004

Roflumilast attenuates pulmonary inflammation upon segmental endotoxin challenge in healthy subjects: a randomized placebo-controlled trial.

scientific article

Safety and efficacy of an inhaled epidermal growth factor receptor inhibitor (BIBW 2948 BS) in chronic obstructive pulmonary disease

scientific article

Safety and tolerability of a novel inhaled GATA3 mRNA targeting DNAzyme in patients with TH2-driven asthma.

scientific article

Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes

scientific article published on 01 June 2003

Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest and During Exercise

scientific article published on 06 January 2020

Surfactant Protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model

scientific article published on February 2012

Surfactant function affected by airway inflammation and cooling: possible impact on exercise-induced asthma

scientific article published on 01 March 2000

Surfactant function in lung transplantation after 24 hours of ischemia: advantage of retrograde flush perfusion for preservation.

scientific article

Surfactant homeostasis is maintained in vivo during keratinocyte growth factor-induced rat lung type II cell hyperplasia

scientific article published on 05 February 2003

Surfactant protein D decreases pollen-induced IgE-dependent mast cell degranulation

scientific article published on 24 June 2005

Surfactant protein D inhibits early airway response in Aspergillus fumigatus-sensitized mice

scientific article published on 01 July 2006

Surfactant protein D modulates pulmonary clearance of pollen starch granules

scientific article published on 01 November 2010

Surfactant protein levels in bronchoalveolar lavage after segmental allergen challenge in patients with asthma

scientific article published on 01 May 2006

Surfactant proteins SP-A and SP-D as modulators of the allergic inflammation in asthma.

scientific article

Surfactant: a review of its functions and relevance in adult respiratory disorders

scientific article published on May 1996

The EvA study: aims and strategy.

scientific article

The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo.

scientific article

The NKT cell ligand αgalactosylceramide suppresses allergic airway inflammation by induction of a Th1 response.

scientific article published on 2 April 2011

The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure

scientific article published on 30 September 2009

The effects of an anti-IL-13 mAb on cytokine levels and nasal symptoms following nasal allergen challenge

scientific article published on 29 June 2011

The inhibition of alpha 1-adrenoceptor-mediated contractions of rabbit pulmonary artery by Ca2+-withdrawal, pertussis toxin and N-ethylmaleimide is dependent on agonist intrinsic efficacy

scientific article published on 01 May 1989

The role of pulmonary surfactant in obstructive airways disease

scientific article published on February 1997

The role of surfactant in asthma

scientific article

Therapeutic surfactants modulate the viability of eosinophils and induce inflammatory mediator release

scientific article published on 17 March 2009

Therapeutic use of surfactant components in allergic asthma

scientific article published on 15 October 2008

Tiotropium Respimat(®) Versus HandiHaler(®): Comparison of Bronchodilator Efficacy of Various Doses in Clinical Trials

scientific article

Type A natriuretic peptides exhibit different bronchoprotective effects in rats

scientific article published on 01 December 1994

Warm or cold ischemia in animal models of lung ischemia-reperfusion injury: is there a difference?

scientific article

[Comparison of four identical electronic noses and three measurement set-ups]

scientific article published on 24 March 2011

[Pathomechanisms in chronic obstructive pulmonary disease (COPD)]

scientific article published on 01 December 2006

[Smelling diseases? A short review on electronic noses]

scientific article published on 16 March 2011

[The prevalence of chronic obstructive pulmonary disease (COPD) in Germany. Results of the BOLD study]

scientific article published on 03 December 2008

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