List of works by Xin-Yuan Guan

A CD90(+) tumor-initiating cell population with an aggressive signature and metastatic capacity in esophageal cancer.

scientific article published on 4 February 2013

A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

scientific article

A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets

scientific article published on 02 March 2020

A rat cell line derived from DMBA-induced mammary carcinoma

scientific article published on May 2003

A targeted disruption of the murine Brca1 gene causes gamma-irradiation hypersensitivity and genetic instability.

scientific article published in December 1998

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

scientific article (publication date: 15 August 1997)

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways.

scientific article published on 18 October 2016

ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling.

scientific article

ANXA3/JNK Signaling Promotes Self-Renewal and Tumor Growth, and Its Blockade Provides a Therapeutic Target for Hepatocellular Carcinoma.

scientific article

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production

scientific article published on 14 January 2019

Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma

scientific article published on 3 December 2013

Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.

scientific article

Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma.

scientific article published on 11 January 2014

Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma.

scientific article

Amplification and overexpression of aurora kinase A (AURKA) in immortalized human ovarian epithelial (HOSE) cells.

scientific article

Amplification and overexpression of epidermal growth factor receptor gene in glioblastomas of Chinese patients correlates with patient's age but not with tumor's clinicopathological pathway

scientific article published on 7 September 2005

Amplification of 19q13.1–q13.2 sequences in ovarian cancer

scientific article published on 01 March 1996

Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization

scientific article published on 01 March 2001

Anti-angiogenic pathway associations of the 3p21.3 mapped BLU gene in nasopharyngeal carcinoma.

scientific article published on 27 October 2014

ApoA-1 accelerates regeneration of small-for-size fatty liver graft after transplantation

scientific article published on 26 October 2018

Array-based comparative genomic hybridization analysis identified cyclin D1 as a target oncogene at 11q13.3 in nasopharyngeal carcinoma

scientific article published on September 2005

Association of mortalin (HSPA9) with liver cancer metastasis and prediction for early tumor recurrence.

scientific article

Author Correction: Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma

scientific article published on 11 June 2020

Biology of hepatic cancer stem cells.

scientific article published on August 2011

C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism

scientific article published on 15 December 2020

C-terminal truncated HBx protein activates caveolin-1/LRP6/β-catenin/FRMD5 axis in promoting hepatocarcinogenesis

scientific article published on 21 December 2018

C-terminal truncated hepatitis B virus X protein promotes hepatocellular carcinogenesis through induction of cancer and stem cell-like properties.

scientific article published on 19 March 2016

CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway

scientific article published on 20 December 2015

CD133(+) liver tumor-initiating cells promote tumor angiogenesis, growth, and self-renewal through neurotensin/interleukin-8/CXCL1 signaling

scientific article published on 13 January 2012

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

scientific article

CD133+ liver cancer stem cells resist interferon-gamma-induced autophagy

scientific article published on 13 January 2016

CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction

scientific article published on 12 January 2016

CHD1L contributes to cisplatin resistance by upregulating the ABCB1-NF-κB axis in human non-small-cell lung cancer

scientific article published on 04 February 2019

CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients.

scientific article

CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors.

scientific article published on 4 March 2016

CLDN14 is epigenetically silenced by EZH2-mediated H3K27ME3 and is a novel prognostic biomarker in hepatocellular carcinoma.

scientific article published on 31 March 2016

CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma

scientific article

COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis

scientific article

CSTF2-Induced Shortening of the 3'UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder

scientific article published on 24 August 2018

Calcium binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating ERK signaling pathway.

scientific article

Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression.

scientific article published on 10 February 2017

Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways.

scientific article published on 21 October 2016

Cell cycle-related kinase supports ovarian carcinoma cell proliferation via regulation of cyclin D1 and is a predictor of outcome in patients with ovarian carcinoma.

scientific article

Cell-specific detection of miR-375 downregulation for predicting the prognosis of esophageal squamous cell carcinoma by miRNA in situ hybridization

scientific article

Characterization of 3p, 5p, and 3q in two nasopharyngeal carcinoma cell lines, using region-specific multiplex fluorescence in situ hybridization probes

scientific article

Characterization of CACNA2D3 as a putative tumor suppressor gene in the development and progression of nasopharyngeal carcinoma.

scientific article published on 13 July 2013

Characterization of HBV integrants in 14 hepatocellular carcinomas: association of truncated X gene and hepatocellular carcinogenesis.

scientific article

Characterization of a candidate tumor suppressor gene uroplakin 1A in esophageal squamous cell carcinoma.

scientific article

Characterization of oncogene-induced metabolic alterations in hepatic cells by using ultrahigh performance liquid chromatography-tandem mass spectrometry

scientific article published on 28 January 2016

Characterization of rearrangements involving 4q, 13q and 16q in hepatocellular carcinoma cell lines using region-specific multiplex-FISH probes

scientific article published on 13 November 2006

Characterization of the oncogenic function of centromere protein F in hepatocellular carcinoma.

scientific article published on 17 June 2013

Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma.

scientific article published on 17 November 2010

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.

scientific article

Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma

scientific article published on 01 June 2020

Chromosome 1q21 amplification and oncogenes in hepatocellular carcinoma.

scientific article published on 02 August 2010

Chromosome 22q11.2 interstitial deletions among childhood-onset schizophrenics and "multidimensionally impaired".

scientific article published in February 1998

Chromosome arm painting probes

scientific article published on 01 January 1996

Clinical significance of CHD1L in hepatocellular carcinoma and therapeutic potentials of virus-mediated CHD1L depletion.

scientific article published on 10 November 2010

Clinicopathological significance of missing in metastasis B expression in hepatocellular carcinoma.

scientific article

Clonal chromosome abnormalities in 54 cases of ovarian carcinoma

scientific article published on 01 March 1994

Clusterin as a predictor for chemoradiotherapy sensitivity and patient survival in esophageal squamous cell carcinoma

scientific article published on 4 September 2009

Clusterin plays an important role in hepatocellular carcinoma metastasis

scientific article published on 01 February 2006

Co-overexpression of fibroblast growth factor 3 and epidermal growth factor receptor is correlated with the development of nonsmall cell lung carcinoma

scientific article published on January 2006

Comparative genomic hybridization: comparison between esophageal squamous cell carcinoma and gastric cardia adenocarcinoma from a high-incidence area for both cancers in Henan, northern China

article

Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance

scientific article published on 16 October 2015

Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma

scientific article published on 09 March 2021

Correlation of AIB1 overexpression with advanced clinical stage of human colorectal carcinoma.

scientific article published in July 2005

Corrigendum to “Alternatively activated (M2) macrophages promote tumour growth and invasiveness in hepatocellular carcinoma” [J Hepatol 2015;62:607–616]

scientific article published on 16 March 2016

Cytogenetic and molecular genetic alterations in hepatocellular carcinoma.

scientific article

DAPK3 inhibits gastric cancer progression via activation of ULK1-dependent autophagy

scientific article published on 09 October 2020

DHRS2 inhibits cell growth and motility in esophageal squamous cell carcinoma.

scientific article

DNA fingerprinting tags novel altered chromosomal regions and identifies the involvement of SOX5 in the progression of prostate cancer

scientific article

Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway.

scientific article published on 20 September 2016

Decreased expression of H3K27me3 in human ovarian carcinomas correlates with more aggressive tumor behavior and poor patient survival

scientific article published on 01 January 2015

Decreased expression of PinX1 protein is correlated with tumor development and is a new independent poor prognostic factor in ovarian carcinoma.

scientific article published on 10 March 2010

Defining early events of Epstein-Barr virus (EBV) infection in immortalized nasopharyngeal epithelial cells using cell-free EBV infection

scientific article published on 28 February 2019

Dendritic cells-mediated CTLs targeting hepatocellular carcinoma stem cells.

scientific article published on 22 August 2010

Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasis

scientific article published on 01 March 2003

Dietary compound isoliquiritigenin prevents mammary carcinogenesis by inhibiting breast cancer stem cells through WIF1 demethylation

scientific article published in April 2015

Different expression of hepatitis B surface antigen between hepatocellular carcinoma and its surrounding liver tissue, studied using a tissue microarray

article

Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines.

scientific article

Down-regulation of POTEG predicts poor prognosis in esophageal squamous cell carcinoma patients.

scientific article published on 22 March 2018

Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.

scientific article published in May 2010

Downregulation of LGI1 promotes tumor metastasis in esophageal squamous cell carcinoma.

scientific article published on 7 February 2014

Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.

scientific article

Downregulation of ZIP kinase is associated with tumor invasion, metastasis and poor prognosis in gastric cancer.

scientific article

Downregulation of the novel tumor suppressor DIRAS1 predicts poor prognosis in esophageal squamous cell carcinoma.

scientific article published on 22 February 2013

EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin.

scientific article published on 20 June 2011

EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients.

scientific article

Epigenetic alterations of a novel antioxidant gene predispose susceptible individuals to increased risk of esophageal cancer

article

Esophageal squamous cell carcinoma (ESCC): advance in genomics and molecular genetics.

scientific article published on 24 June 2013

Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line HKESC-4 of Chinese origin

scientific article

Establishment and characterization of human non-small cell lung cancer cell lines

scientific article published on 3 October 2011

Establishment of cell lines from a primary hepatocellular carcinoma and its metastatis

scientific article published on January 2004

Eukaryotic Initiation Factor 5A2 Contributes to the Maintenance of CD133(+) Hepatocellular Carcinoma Cells via the c-Myc/microRNA-29b Axis

scientific article published on 9 November 2017

Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells.

scientific article

Evaluation of circulating EBV microRNA BART2-5p in facilitating early detection and screening of nasopharyngeal carcinoma

scientific article published on 15 November 2018

Evaluation of serum clusterin as a surveillance tool for human hepatocellular carcinoma with hepatitis B virus related cirrhosis.

scientific article published in June 2010

Exome sequencing reveals the genetic landscape and frequent inactivation of PCDHB3 in Chinese rectal cancers.

scientific article published on 14 March 2018

Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis

scientific article published on 29 August 2018

Expression and amplification of eIF-5A2 in human epithelial ovarian tumors and overexpression of EIF-5A2 is a new independent predictor of outcome in patients with ovarian carcinoma.

scientific article

Expression of EIF5A2 associates with poor survival of nasopharyngeal carcinoma patients treated with induction chemotherapy.

scientific article

FSTL1 Promotes Metastasis and Chemoresistance in Esophageal Squamous Cell Carcinoma through NFκB-BMP Signaling Cross-talk.

scientific article

FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma

scientific article published on 26 July 2017

Fascin over-expression is associated with aggressiveness of oral squamous cell carcinoma

scientific article published on 11 May 2007

Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma.

scientific article

Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection.

scientific article

Genetic changes in human fetuses from spontaneous abortion after in vitro fertilization detected by comparative genomic hybridization

scientific article published on 15 October 2003

Genomic instability in laminopathy-based premature aging

scientific article

H3K27me3 protein is a promising predictive biomarker of patients' survival and chemoradioresistance in human nasopharyngeal carcinoma

scientific article published on 5 July 2011

HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma

scientific article published on 05 August 2015

HN1L-mediated transcriptional axis AP-2γ/METTL13/TCF3-ZEB1 drives tumor growth and metastasis in hepatocellular carcinoma

scientific article published on 18 February 2019

HOXC10 upregulation confers resistance to chemoradiotherapy in ESCC tumor cells and predicts poor prognosis

scientific article published on 25 June 2020

Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial

scientific article

Heterogeneous expression and association of ?-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray

scientific article published on 01 December 2003

High Expression of p300 in Human Breast Cancer Correlates with Tumor Recurrence and Predicts Adverse Prognosis.

scientific article published on September 2011

High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy

scientific article published on 01 July 2010

High expression of H3K27me3 in human hepatocellular carcinomas correlates closely with vascular invasion and predicts worse prognosis in patients.

scientific article

High levels of CCL2 or CCL4 in the tumor microenvironment predict unfavorable survival in lung adenocarcinoma.

scientific article published on 2 May 2018

High-density allelotyping of chromosome 8p in hepatocellular carcinoma and clinicopathologic correlation

scientific article published on 01 June 2002

High-level expression of Rad51 is an independent prognostic marker of survival in non-small-cell lung cancer patients

scientific article

High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers

scientific article

High-throughput tissue microarray analysis of c-myc activation in chronic liver diseases and hepatocellular carcinoma

article

Human artificial chromosomes generated by modification of a yeast artificial chromosome containing both human alpha satellite and single-copy DNA sequences.

scientific article

Hypoxia restrains the expression of complement component 9 in tumor-associated macrophages promoting non-small cell lung cancer progression.

scientific article

ITPKA expression is a novel prognostic factor in hepatocellular carcinoma

scientific article published on 7 August 2015

Identification and characterization of a novel melanoma tumor suppressor gene on human chromosome 6q21.

scientific article

Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma.

scientific article

Identification of alpha-actinin 4 and 67 kDa laminin receptor as stage-specific markers in esophageal cancer via proteomic approaches.

scientific article

Identification of chemokine CXCL10 in tumor microenvironment by antibody array as a prognostic marker in hepatocellular carcinoma.

scientific article

Identification of cryptic sites of DNA sequence amplification in human breast cancer by chromosome microdissection

scientific article published on 01 October 1994

Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese

scientific article

Identification of miR-29c and its Target FBXO31 as a Key Regulatory Mechanism in Esophageal Cancer Chemoresistance: Functional Validation and Clinical Significance

scientific article published on 28 February 2019

Impact of G₂ checkpoint defect on centromeric instability.

scientific article published on 8 November 2010

In search of liver cancer stem cells.

scientific article published on 29 July 2008

Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma.

scientific article published on 21 February 2014

Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer

scientific article published on 6 May 2015

Increased expression of annexin I is associated with drug-resistance in nasopharyngeal carcinoma and other solid tumors

scientific article

Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma.

scientific article published on 07 December 2016

Intensive expression of Bmi-1 is a new independent predictor of poor outcome in patients with ovarian carcinoma.

scientific article

Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression.

scientific article

Interleukin 23 promotes hepatocellular carcinoma metastasis via NF-kappa B induced matrix metalloproteinase 9 expression

scientific article

Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

scientific article published on February 2008

Isoliquiritigenin modulates miR-374a/PTEN/Akt axis to suppress breast cancer tumorigenesis and metastasis

scientific article published on 21 August 2017

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway

scientific article published on 24 January 2019

Loss of ATOH8 Increases Stem Cell Features of Hepatocellular Carcinoma Cells

scientific article

Loss of cell adhesion molecule L1 like promotes tumor growth and metastasis in esophageal squamous cell carcinoma

scientific article published on 08 January 2019

Lymphoid enhancer-binding factor-1 promotes stemness and poor differentiation of hepatocellular carcinoma by directly activating the NOTCH pathway

scientific article published on 29 January 2019

Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt/GSK-3β/Snail signaling.

scientific article published on 23 December 2013

Malignant placental site trophoblastic tumor

scientific article published on 01 April 2002

Membrane Metalloendopeptidase (MME) Suppresses Metastasis of Esophageal Squamous Cell Carcinoma (ESCC) by Inhibiting FAK-RhoA Signaling Axis

scientific article published on 02 May 2019

Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts.

scientific article published on August 2016

MiRegulators in cancer stem cells of solid tumors.

scientific article published on 15 February 2011

MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.

scientific article

MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression

scientific article published on 01 November 2011

MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF

scientific article

MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma

scientific article

Microtubule breakage is not a major mechanism for resolving end-to-end chromosome fusions generated by telomere dysfunction during the early process of immortalization.

scientific article published on 28 August 2007

Monoclonal antibodies specific to human Δ42PD1: A novel immunoregulator potentially involved in HIV-1 and tumor pathogenesis.

scientific article

NRIP3 upregulation confers resistance to chemoradiotherapy in ESCC via RTF2 removal by accelerating ubiquitination and degradation of RTF2

scientific article published on 24 August 2020

Neuropilin-2 promotes tumourigenicity and metastasis in oesophageal squamous cell carcinoma through ERK-MAPK-ETV4-MMP-E-cadherin deregulation.

scientific article published on 11 April 2016

Nuclear DLC1 exerts oncogenic function through association with FOXK1 for cooperative activation of MMP9 expression in melanoma

scientific article published on 25 March 2020

Octamer 4/microRNA-1246 signaling axis drives Wnt/β-catenin activation in liver cancer stem cells.

scientific article published on 17 September 2016

Overexpression of AIB1 in Nasopharyngeal Carcinomas Correlates Closely With Advanced Tumor Stage

scientific article published on 01 May 2008

Overexpression of AIB1 negatively affects survival of surgically resected non-small-cell lung cancer patients

scientific article published on 11 January 2010

Overexpression of AIB1 predicts resistance to chemoradiotherapy and poor prognosis in patients with primary esophageal squamous cell carcinoma.

scientific article published on 18 May 2009

Overexpression of CHD1L is positively associated with metastasis of lung adenocarcinoma and predicts patients poor survival.

scientific article published on 24 August 2015

Overexpression of EIF-5A2 predicts tumor recurrence and progression in pTa/pT1 urothelial carcinoma of the bladder.

scientific article

Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce epithelial-mesenchymaltransition.

scientific article published on 3 August 2011

Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.

scientific article

Overexpression of HN1L promotes cell malignant proliferation in non-small cell lung cancer.

scientific article

Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma

scientific article published on 21 November 2017

Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility.

scientific article

Overexpression of YKL-40 is an independent prognostic marker in gastric cancer

scientific article published on 17 September 2009

Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

scientific article

Overexpression of clusterin correlates with tumor progression, metastasis in gastric cancer: a study on tissue microarrays

scientific article published on 01 January 2010

Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability

scientific article

Overexpression of eIF5A-2 is an adverse prognostic marker of survival in stage I non-small cell lung cancer patients.

scientific article

Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.

scientific article

Overexpression of maelstrom promotes bladder urothelial carcinoma cell aggressiveness by epigenetically downregulating MTSS1 through DNMT3B.

scientific article

Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.

scientific article published on 28 November 2011

Overexpression of ubiquitin specific peptidase 14 predicts unfavorable prognosis in esophageal squamous cell carcinoma

scientific article

PDSS2 Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism

scientific article published on 02 July 2018

PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors

scientific article published on 26 January 2021

PIM2 promotes hepatocellular carcinoma tumorigenesis and progression through activating NF-κB signaling pathway

scientific article published on 02 July 2020

PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation

scientific article published on 01 October 2018

PSCA acts as a tumor suppressor by facilitating the nuclear translocation of RB1CC1 in esophageal squamous cell carcinoma.

scientific article published on 19 January 2016

Patient-physician trust in China: health education for the public.

scientific article

Pericentromeric regions are refractory to prompt repair after replication stress-induced breakage in HPV16 E6E7-expressing epithelial cells.

scientific article

Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer.

scientific article

Podoplanin‑positive cancer cells at the edge of esophageal squamous cell carcinomas are involved in invasion

scientific article

Profiling of Epstein-Barr virus-encoded microRNAs in nasopharyngeal carcinoma reveals potential biomarkers and oncomirs.

scientific article published on 30 June 2011

Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma

scientific article

Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma.

scientific article published on August 2010

Prognostic significance of FAM3C in esophageal squamous cell carcinoma.

scientific article

Prognostic significance ofc-myc andAIB1 amplification in hepatocellular carcinoma

scientific article published on 01 December 2002

Protein expression and amplification of AIB1 in human urothelial carcinoma of the bladder and overexpression of AIB1 is a new independent prognostic marker of patient survival

scientific article published in June 2008

Proteomic analysis of a nasopharyngeal carcinoma cell line and a nasopharyngeal epithelial cell line.

scientific article

RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis

scientific article

RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-κB Signaling and MMP1 Expression.

scientific article published in January 2018

RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer.

scientific article published on 22 May 2017

Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma.

scientific article

Rac activation is associated with hepatocellular carcinoma metastasis by up-regulation of vascular endothelial growth factor expression

scientific article published on September 2006

Rapid assessment of the coenzyme Q10redox state using ultrahigh performance liquid chromatography tandem mass spectrometry

scientific article published on 01 November 2014

Rapid generation of region specific probes by chromosome microdissection and their application

scientific article published on 01 April 1992

Rapid generation of region-specific genomic clones by chromosome microdissection: isolation of DNA from a region frequently deleted in malignant melanoma.

scientific article

Recurrent chromosomal imbalances in nonsmall cell lung carcinoma

scientific article published on 01 May 2004

Recurrent chromosome alterations in hepatocellular carcinoma detected by comparative genomic hybridization

scientific article published on 01 October 2000

Recurrent chromosome changes in 62 primary gastric carcinomas detected by comparative genomic hybridization

scientific article published on 01 November 2000

Recurrent genetic alterations in 26 colorectal carcinomas and 21 adenomas from Chinese patients

article

Reduction of AZGP1 predicts poor prognosis in esophageal squamous cell carcinoma patients in Northern China

scientific article published on 20 December 2016

Regulation of angiogenesis by Id-1 through hypoxia-inducible factor-1alpha-mediated vascular endothelial growth factor up-regulation in hepatocellular carcinoma

scientific article published on December 2006

Regulatory role of miR-142-3p on the functional hepatic cancer stem cell marker CD133.

scientific article published on July 2014

Role of AMPK signaling in mediating the anticancer effects of silibinin in esophageal squamous cell carcinoma

scientific article published on 15 November 2015

Role of short telomeres in inducing preferential chromosomal aberrations in human ovarian surface epithelial cells: A combined telomere quantitative fluorescence in situ hybridization and whole-chromosome painting study.

scientific article published on May 2003

Role of translationally controlled tumor protein in cancer progression.

scientific article published on 17 April 2012

Roles of eukaryotic initiation factor 5A2 in human cancer.

scientific article published on 12 October 2013

S-Dimethylarsino-glutathione (darinaparsin®) targets histone H3.3, leading to TRAIL-induced apoptosis in leukemia cells

scientific article published on 01 October 2019

SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma.

scientific article published on 7 May 2012

SOX9 is a dose-dependent metastatic fate determinant in melanoma

scientific article published on 14 January 2019

SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice.

scientific article published on 25 September 2012

SRC-3/AIB1 protein and gene amplification levels in human esophageal squamous cell carcinomas

article

Sei-1 promotes double minute chromosomes formation through activation of the PI3K/Akt/BRCA1-Abraxas pathway and induces double-strand breaks in NIH-3T3 fibroblasts.

scientific article published in March 2018

Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma.

scientific article published on 23 April 2012

Significance of PI3K/AKT signaling pathway in metastasis of esophageal squamous cell carcinoma and its potential as a target for anti-metastasis therapy

scientific article

Significance of TWIST expression and its association with E-cadherin in bladder cancer

article

Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.

scientific article

Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development

scientific article published on 6 March 2017

Spatholobus suberectus inhibits cancer cell growth by inducing apoptosis and arresting cell cycle at G2/M checkpoint ⬇️

scientific article published on November 10, 2010

Stemness and chemotherapeutic drug resistance induced by EIF5A2 overexpression in esophageal squamous cell carcinoma

scientific article

Steroidogenic factor-1 is an essential transcriptional activator for gonad-specific expression of promoter I of the rat prolactin receptor gene

scientific article published on May 1997

Suppression of esophageal tumor growth and chemoresistance by directly targeting the PI3K/AKT pathway.

scientific article

Systemic delivery of microRNA-101 potently inhibits hepatocellular carcinoma in vivo by repressing multiple targets

scientific article

TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma

scientific article published on 3 July 2017

TROP-2 exhibits tumor suppressive functions in cervical cancer by dual inhibition of IGF-1R and ALK signaling

scientific article published on 12 November 2018

TSPAN15 interacts with BTRC to promote oesophageal squamous cell carcinoma metastasis via activating NF-κB signaling.

scientific article published on 12 April 2018

Telomere capture stabilizes chromosome breakage

The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therapeutic Resistance in Nasopharyngeal Carcinoma.

scientific article published on 13 November 2017

The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update

scientific article

The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2.

scientific article published on 14 June 2011

Transforming growth factor beta1 promotes chromosomal instability in human papillomavirus 16 E6E7-infected cervical epithelial cells.

scientific article

Transgenic CHD1L expression in mouse induces spontaneous tumors

scientific article

Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition.

scientific article published on September 2006

Up-regulated expression of cytoplasmic clusterin in human ovarian carcinoma

scientific article published on 01 January 2005

Up-regulation of fibroblast growth factor 3 is associated with tumor metastasis and recurrence in human hepatocellular carcinoma

scientific article published on 9 January 2007

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma.

scientific article published on 2 March 2017

Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway.

scientific article published on 14 June 2011

Zipper-interacting protein kinase promotes epithelial-mesenchymal transition, invasion and metastasis through AKT and NF-kB signaling and is associated with metastasis and poor prognosis in gastric cancer patients

scientific article published on April 2015

[Significance of hydroxymethylglutaryl-CoA synthase 2 on prognosis of esophageal squamous cell carcinoma]

scientific article published on 01 October 2018

miR-31 is consistently inactivated in EBV-associated nasopharyngeal carcinoma and contributes to its tumorigenesis

scientific article

microRNA-146 up-regulation predicts the prognosis of non-small cell lung cancer by miRNA in situ hybridization.

scientific article published on 18 January 2014

p21/Cyclin E pathway modulates anticlastogenic function of Bmi-1 in cancer cells.

scientific article published on 7 August 2014

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