List of works - Li Fu

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

scientific article published on 23 July 2018

Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma.

scientific article published on 11 January 2014

Antitumor activity of a novel small molecule TLR7 agonist via immune response induction and tumor microenvironment modulation

scientific article published on 18 November 2015

BCSG1 siRNA delivered by lentiviral vector suppressed proliferation and migration of MDA-MB-231 cells.

scientific article

CHL1 suppresses tumor growth and metastasis in nasopharyngeal carcinoma by repressing PI3K/AKT signaling pathway via interaction with Integrin β1 and Merlin

scientific article published on 11 July 2019

COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis

scientific article

Cell-specific detection of miR-375 downregulation for predicting the prognosis of esophageal squamous cell carcinoma by miRNA in situ hybridization

scientific article

Characterization of a novel mechanism of genomic instability involving the SEI1/SET/NM23H1 pathway in esophageal cancers

scientific article published on 22 June 2010

Characterization of oncogene-induced metabolic alterations in hepatic cells by using ultrahigh performance liquid chromatography-tandem mass spectrometry

scientific article published on 28 January 2016

Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma

scientific article

Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma.

scientific article published on 17 November 2010

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.

scientific article

Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.

scientific article published in May 2010

Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.

scientific article

E6 protein expressed by high-risk HPV activates super-enhancers of the EGFR and c-MET oncogenes by destabilizing the histone demethylase KDM5C.

scientific article published on 16 January 2018

Epigenetic alterations of a novel antioxidant gene predispose susceptible individuals to increased risk of esophageal cancer

article

Esophageal squamous cell carcinoma (ESCC): advance in genomics and molecular genetics.

scientific article published on 24 June 2013

Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells.

scientific article

FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma

scientific article published on 26 July 2017

Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma.

scientific article

Frequent concomitant epigenetic silencing of the stress-responsive tumor suppressor gene CADM1, and its interacting partner DAL-1 in nasal NK/T-cell lymphoma.

scientific article

Frizzled Receptors as Potential Therapeutic Targets in Human Cancers.

scientific article published on 22 May 2018

Frizzled7 Promotes Epithelial-to-mesenchymal Transition and Stemness Via Activating Canonical Wnt/β-catenin Pathway in Gastric Cancer

scientific article published on 12 February 2018

Genome-wide gene expression profile analyses identify CTTN as a potential prognostic marker in esophageal cancer

scientific article

HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma

scientific article published on 05 August 2015

High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers

scientific article

Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1

scientific article published on 20 November 2018

Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma.

scientific article

Identification of alpha-actinin 4 and 67 kDa laminin receptor as stage-specific markers in esophageal cancer via proteomic approaches.

scientific article

Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese

scientific article

Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method

scientific article published on 30 July 2020

Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma.

scientific article published on 21 February 2014

Increased expression of annexin I is associated with drug-resistance in nasopharyngeal carcinoma and other solid tumors

scientific article

Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma.

scientific article published on 07 December 2016

Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

scientific article published on February 2008

MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.

scientific article

O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress.

scientific article published on 24 March 2017

Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.

scientific article

Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.

scientific article

Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.

scientific article published on 28 November 2011

PSCA acts as a tumor suppressor by facilitating the nuclear translocation of RB1CC1 in esophageal squamous cell carcinoma.

scientific article published on 19 January 2016

Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer.

scientific article

Podoplanin‑positive cancer cells at the edge of esophageal squamous cell carcinomas are involved in invasion

scientific article

Polarity-Tuning Derivatization-LC-MS Approach for Probing Global Carboxyl-Containing Metabolites in Colorectal Cancer

scientific article published on 20 September 2018

RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis

scientific article

RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer.

scientific article published on 22 May 2017

Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions

scientific article published on 16 February 2016

Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.

scientific article

Small Heat Shock Proteins in Cancers: Functions and Therapeutic Potential for Cancer Therapy

scientific article published on 10 September 2020

Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target

scientific article published on 01 April 2018

The T393C polymorphism of GNAS1 as a predictor for chemotherapy sensitivity and survival in advanced non-small-cell lung cancer patients treated with gemcitabine plus platinum

scientific article published on 28 February 2012

The immune landscape of esophageal cancer

scientific article published on 26 November 2019

Therapeutic targeting of the crosstalk between cancer-associated fibroblasts and cancer stem cells

scientific article published on 01 September 2019

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma.

scientific article published on 2 March 2017

Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway.

scientific article published on 14 June 2011

List of works by Li Fu

A SIRT1-centered circuitry regulates breast cancer stemness and metastasis

Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma.

Antitumor activity of a novel small molecule TLR7 agonist via immune response induction and tumor microenvironment modulation

BCSG1 siRNA delivered by lentiviral vector suppressed proliferation and migration of MDA-MB-231 cells.

CHL1 suppresses tumor growth and metastasis in nasopharyngeal carcinoma by repressing PI3K/AKT signaling pathway via interaction with Integrin β1 and Merlin

COOH-terminal truncated HBV X protein plays key role in hepatocarcinogenesis

Cell-specific detection of miR-375 downregulation for predicting the prognosis of esophageal squamous cell carcinoma by miRNA in situ hybridization

Characterization of a novel mechanism of genomic instability involving the SEI1/SET/NM23H1 pathway in esophageal cancers

Characterization of oncogene-induced metabolic alterations in hepatic cells by using ultrahigh performance liquid chromatography-tandem mass spectrometry

Characterization of tumor suppressive function of P300/CBP-associated factor at frequently deleted region 3p24 in esophageal squamous cell carcinoma

Characterization of tumor-suppressive function of SOX6 in human esophageal squamous cell carcinoma.

Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.

Down-regulation of tyrosine aminotransferase at a frequently deleted region 16q22 contributes to the pathogenesis of hepatocellular carcinoma.

Downregulation of RBMS3 is associated with poor prognosis in esophageal squamous cell carcinoma.

E6 protein expressed by high-risk HPV activates super-enhancers of the EGFR and c-MET oncogenes by destabilizing the histone demethylase KDM5C.

Epigenetic alterations of a novel antioxidant gene predispose susceptible individuals to increased risk of esophageal cancer

Esophageal squamous cell carcinoma (ESCC): advance in genomics and molecular genetics.

Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells.

FZD7 is a novel prognostic marker and promotes tumor metastasis via WNT and EMT signaling pathways in esophageal squamous cell carcinoma

Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma.

Frequent concomitant epigenetic silencing of the stress-responsive tumor suppressor gene CADM1, and its interacting partner DAL-1 in nasal NK/T-cell lymphoma.

Frizzled Receptors as Potential Therapeutic Targets in Human Cancers.

Frizzled7 Promotes Epithelial-to-mesenchymal Transition and Stemness Via Activating Canonical Wnt/β-catenin Pathway in Gastric Cancer

Genome-wide gene expression profile analyses identify CTTN as a potential prognostic marker in esophageal cancer

HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma

High-throughput loss-of-heterozygosity study of chromosome 3p in lung cancer using single-nucleotide polymorphism markers

Histone Demethylase KDM4B Promotes DNA Damage by Activating Long Interspersed Nuclear Element-1

Identification of PTK6, via RNA sequencing analysis, as a suppressor of esophageal squamous cell carcinoma.

Identification of alpha-actinin 4 and 67 kDa laminin receptor as stage-specific markers in esophageal cancer via proteomic approaches.

Identification of genes with allelic imbalance on 6p associated with nasopharyngeal carcinoma in southern Chinese

Improving the diversity of captured full-length isoforms using a normalized single-molecule RNA-sequencing method

Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma.

Increased expression of annexin I is associated with drug-resistance in nasopharyngeal carcinoma and other solid tumors

Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma.

Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma.

MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.

O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress.

Overexpression of GPR39 contributes to malignant development of human esophageal squamous cell carcinoma.

Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma.

Overexpression of matrix metalloproteinase 10 is associated with poor survival in patients with early stage of esophageal squamous cell carcinoma.

PSCA acts as a tumor suppressor by facilitating the nuclear translocation of RB1CC1 in esophageal squamous cell carcinoma.

Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer.

Podoplanin‑positive cancer cells at the edge of esophageal squamous cell carcinomas are involved in invasion

Polarity-Tuning Derivatization-LC-MS Approach for Probing Global Carboxyl-Containing Metabolites in Colorectal Cancer

RBMS3 at 3p24 inhibits nasopharyngeal carcinoma development via inhibiting cell proliferation, angiogenesis, and inducing apoptosis

RNA editing of SLC22A3 drives early tumor invasion and metastasis in familial esophageal cancer.

Regulatory role of hexosamine biosynthetic pathway on hepatic cancer stem cell marker CD133 under low glucose conditions

Single-nucleotide polymorphism-mass array reveals commonly deleted regions at 3p22 and 3p14.2 associate with poor clinical outcome in esophageal squamous cell carcinoma.

Small Heat Shock Proteins in Cancers: Functions and Therapeutic Potential for Cancer Therapy

Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target

The T393C polymorphism of GNAS1 as a predictor for chemotherapy sensitivity and survival in advanced non-small-cell lung cancer patients treated with gemcitabine plus platinum

The immune landscape of esophageal cancer

Therapeutic targeting of the crosstalk between cancer-associated fibroblasts and cancer stem cells

Urokinase plasminogen activator secreted by cancer-associated fibroblasts induces tumor progression via PI3K/AKT and ERK signaling in esophageal squamous cell carcinoma.

Wnt2 secreted by tumour fibroblasts promotes tumour progression in oesophageal cancer by activation of the Wnt/β-catenin signalling pathway.