List of works - Oommen P. Varghese

4'-Guanidinium-modified siRNA: a molecular tool to control RNAi activity through RISC priming and selective antisense strand loading

scientific article published on 01 July 2019

An Unexpected Role of Hyaluronic Acid in Trafficking siRNA Across the Cellular Barrier: The First Biomimetic, Anionic, Non-Viral Transfection Method

scientific article published on 31 January 2019

Cell type and transfection reagent-dependent effects on viability, cell content, cell cycle and inflammation of RNAi in human primary mesenchymal cells

scientific article published on 15 December 2013

Chondroitin sulfate coated gold nanoparticles: a new strategy to resolve multidrug resistance and thromboinflammation.

scientific article published on 20 November 2015

Chondroitin sulfate derived theranostic nanoparticles for targeted drug delivery

scientific article published on 01 August 2016

Conformationally constrained 2'-N,4'-C-ethylene-bridged thymidine (aza-ENA-T): synthesis, structure, physical, and biochemical studies of aza-ENA-T-modified oligonucleotides.

scientific article

Critical assessment of rhBMP-2 mediated bone induction: an in vitro and in vivo evaluation.

scientific article published on 10 August 2012

First Aldol Cross-Linked Hyaluronic Acid Hydrogel: Fast and Hydrolytically Stable Hydrogel with Tissue Adhesive Properties

scientific article published on 04 October 2019

Functionalization of hyaluronic acid with chemoselective groups via a disulfide-based protection strategy for in situ formation of mechanically stable hydrogels

scientific article published on September 2010

Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment

scientific article published on 3 August 2017

In situ cross-linkable high molecular weight hyaluronan-bisphosphonate conjugate for localized delivery and cell-specific targeting: a hydrogel linked prodrug approach

scientific article

Innovative Strategy for 3D Transfection of Primary Human Stem Cells with BMP-2 Expressing Plasmid DNA: A Clinically Translatable Strategy for Ex Vivo Gene Therapy ⬇️

article

Insights into siRNA Transfection in Suspension: Efficient Gene Silencing in Human Mesenchymal Stem Cells Encapsulated in Hyaluronic Acid Hydrogel

scientific article published on 08 February 2019

Insights into the mechanism and catalysis of oxime coupling chemistry at physiological pH

scientific article published on 03 March 2015

Mild and efficient strategy for site-selective aldehyde modification of glycosaminoglycans: tailoring hydrogels with tunable release of growth factor

scientific article published on 7 June 2013

Minimally invasive mandibular bone augmentation using injectable hydrogels.

scientific article published on 3 September 2012

Modular approach to functional hyaluronic acid hydrogels using orthogonal chemical reactions.

scientific article published on 5 October 2010

Modulating Thiol p Ka Promotes Disulfide Formation at Physiological pH: An Elegant Strategy To Design Disulfide Cross-Linked Hyaluronic Acid Hydrogels

scientific article published on 13 February 2019

Multifunctional Hyaluronic Acid and Chondroitin Sulfate Nanoparticles: Impact of Glycosaminoglycan Presentation on Receptor Mediated Cellular Uptake and Immune Activation.

scientific article published on 28 July 2016

PLGA/PEG-hydrogel composite scaffolds with controllable mechanical properties

scientific article published on 29 January 2013

Saline Accelerates Oxime Reaction with Aldehyde and Keto Substrates at Physiological pH.

scientific article published in February 2018

Synthesis of guanidinium-modified hyaluronic Acid hydrogel

scientific article published on 17 May 2010

Synthetic design of growth factor sequestering extracellular matrix mimetic hydrogel for promoting in vivo bone formation.

scientific article published on 3 February 2018

Tailored doxorubicin-hyaluronan conjugate as a potent anticancer glyco-drug: an alternative to prodrug approach

scientific article published on 15 October 2013

The chemical nature of the 2′-substituent in the pentose-sugar dictates the pseudoaromatic character of the nucleobase (pKa) in DNA/RNA

scientific article published on 30 March 2006

Thiazolidine chemistry revisited: a fast, efficient and stable click-type reaction at physiological pH

scientific article published on 01 November 2018

List of works by Oommen P. Varghese