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List of works by Pedro Zapater

5-Fluorouracil adjuvant chemotherapy does not increase survival in patients with CpG island methylator phenotype colorectal cancer.

scientific article

A Beta-2-Adrenergic Receptor Activates Adenylate Cyclase in Human Erythrocyte Membranes at Physiological Calcium Plasma Concentrations

scientific article published on 01 June 2000

A Case of Toxic Epidermal Necrolysis Secondary to Acetaminophen in a Child

scientific article published on 20 September 2015

A new Poisson and Bayesian-based method to assign risk and causality in patients with suspected hepatic adverse drug reactions: a report of two new cases of ticlopidine-induced hepatotoxicity

scientific article published in January 2002

A prospective study of the clarithromycin-digoxin interaction in elderly patients

scientific article published in October 2002

A sequential study of serum bacterial DNA in patients with advanced cirrhosis and ascites.

scientific article

AIM2 deficiency reduces the development of hepatocellular carcinoma in mice

scientific article published on 09 October 2018

Actual Anti-TNF Trough Levels Relate to Serum IL-10 in Drug-Responding Patients With Crohn's Disease

scientific article published on 01 July 2019

Acute and chronic hemodynamic changes after propranolol in patients with cirrhosis under primary and secondary prophylaxis of variceal bleeding: a pilot study

scientific article published in May 2010

Acute effects of dipyrone on renal function in patients with cirrhosis: a randomized controlled trial

scientific article published on 08 October 2014

Acute hepatitis in a patient with cirrhosis and hepatocellular carcinoma treated with sorafenib.

scientific article

An international multicenter study of early intravenous fluid administration and outcome in acute pancreatitis

scientific article published on 20 September 2016

Anti-TNF-alpha loss of response is associated with a decreased percentage of FoxP3+ T cells and a variant NOD2 genotype in patients with Crohn's disease

scientific article published on 11 December 2014

Anticonvulsant effects of nimodipine and two novel dihydropyridines (PCA 50922 and PCA 50941) against seizures elicited by pentylenetetrazole and electroconvulsive shock in mice

scientific article published in June 1998

Antimicrobial peptide response to blood translocation of bacterial DNA in Crohn's disease is affected by NOD2/CARD15 genotype

scientific article published on 15 November 2010

Automated low flow pump system for the treatment of refractory ascites: a multi-center safety and efficacy study

scientific article published on 11 January 2013

Bacterial DNA activates cell mediated immune response and nitric oxide overproduction in peritoneal macrophages from patients with cirrhosis and ascites.

scientific article published on June 2004

Bacterial DNA in patients with cirrhosis and noninfected ascites mimics the soluble immune response established in patients with spontaneous bacterial peritonitis

scientific article

Bacterial DNA induces the complement system activation in serum and ascitic fluid from patients with advanced cirrhosis

scientific article published on 03 April 2007

Bacterial DNA translocation contributes to systemic inflammation and to minor changes in the clinical outcome of liver transplantation

scientific article published in Scientific Reports

Bacterial DNA translocation holds increased insulin resistance and systemic inflammatory levels in morbid obese patients.

scientific article published on 15 April 2014

Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients

scientific article published on 19 June 2020

Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites

scientific article published on 27 December 2006

Beta-adrenergic receptor 1 selective antagonism inhibits norepinephrine-mediated TNF-alpha downregulation in experimental liver cirrhosis

scientific article (publication date: 2012)

Bifidobacterium pseudocatenulatum CECT7765 induces an M2 anti-inflammatory transition in macrophages from patients with cirrhosis.

scientific article published on 31 August 2015

Bifidobacterium pseudocatenulatum CECT7765 promotes a TLR2-dependent anti-inflammatory response in intestinal lymphocytes from mice with cirrhosis.

scientific article published on 6 February 2015

Brain edema dynamics in patients with overt hepatic encephalopathy A magnetic resonance imaging study.

scientific article

Causality assessment of liver injury after chronic oral amiodarone intake.

scientific article

Clinical effects and safety of different strategies for administering intravenous diuretics in acutely decompensated heart failure: a randomised clinical trial.

scientific article published on 22 June 2013

Clinical significance of extrapyramidal signs in patients with cirrhosis

scientific article published in May 2005

Colorectal cancer molecular classification using BRAF, KRAS, microsatellite instability and CIMP status: Prognostic implications and response to chemotherapy

scientific article published in PLoS ONE

Comparative pharmacoeconomic study of vancomycin and teicoplanin in intensive care patients

scientific article

Comparison of staging systems to predict survival in hepatocellular carcinoma.

scientific article published in August 2006

Comparison of the in vitro susceptibility of rifaximin versus norfloxacin against multidrug resistant bacteria in a hospital setting. A proof-of-concept study for use in advanced cirrhosis

scientific article published on 01 April 2015

Cytokine association with bacterial DNA in serum of patients with inflammatory bowel disease

scientific article published on 01 April 2009

Density of apamin-sensitive Ca(2+)-dependent K+ channels in bovine chromaffin cells: relevance to secretion

scientific article

Dual-specificity phosphatase 6 regulates CD4+ T-cell functions and restrains spontaneous colitis in IL-10-deficient mice

scientific article

Effects of dotarizine and flunarizine on chromaffin cell viability and cytosolic Ca2+.

scientific article

Effects of omega-conotoxin MVIIC on veratridine-induced cytotoxicity and cytosolic Ca(2+) oscillations

scientific article published in April 1996

Endoscopist characteristics that influence the quality of colonoscopy

scientific article published on 4 February 2016

Extrapyramidal signs predict the development of overt hepatic encephalopathy in patients with liver cirrhosis

scientific article published in May 2010

Functional status of beta-2-adrenoceptor in isolated membranes of mature erythrocytes from patients with cirrhosis and oesophageal varices

scientific article

Functionality of beta-adrenergic receptors in patients with cirrhosis treated chronically with non-selective beta-blockers

scientific article published on 03 September 2020

Gender differences in angiotensin-converting enzyme (ACE) activity and inhibition by enalaprilat in healthy volunteers

scientific article published in May 2004

Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease.

scientific article published in February 2013

Grade of soluble inflammatory response is mainly affected by circulating bacterial DNA concentrations in cirrhosis.

scientific article published on 14 March 2016

Gut Bacterial DNA Translocation is an Independent Risk Factor of Flare at Short Term in Patients With Crohn's Disease

scientific article published on 23 February 2016

Hepatotoxicity related to paraquat and diquat absorption through intact skin.

scientific article published on 15 February 2007

IL26 modulates cytokine response and anti-TNF consumption in Crohn's disease patients with bacterial DNA.

scientific article

Immunomodulating effects of antibiotics used in the prophylaxis of bacterial infections in advanced cirrhosis

scientific article

Increased Risk of Colorectal Cancer in Patients With Multiple Serrated Polyps and Their First-Degree Relatives.

scientific article published on 8 April 2017

Intracellular cytokine expression in peritoneal monocyte/macrophages obtained from patients with cirrhosis and presence of bacterial DNA.

scientific article published on January 2005

Ketanserin potentiates morphine-induced antinociception mediated by kappa-receptor activation

scientific article published on 21 March 2011

Lactulose reduces bacterial DNA translocation, which worsens neurocognitive shape in cirrhotic patients with minimal hepatic encephalopathy

scientific article published on 29 July 2016

Measurement of tobramycin in bronchoalveolar lavage fluid by a modified fluorescence polarization immunoassay

scientific article published on 01 December 1995

Minimal hepatic encephalopathy and extrapyramidal signs in patients with cirrhosis

scientific article published in July 2003

Mismatch repair status in the prediction of benefit from adjuvant fluorouracil chemotherapy in colorectal cancer

scientific article published on 18 November 2005

Modifiable endoscopic factors that influence the adenoma detection rate in colorectal cancer screening colonoscopies

Neuroprotection by the novel calcium antagonist PCA50938, nimodipine and flunarizine, in gerbil global brain ischemia

scientific article

Nitric oxide in ascitic fluid is an independent predictor of the development of renal impairment in patients with cirrhosis and spontaneous bacterial peritonitis

scientific article published in June 2004

Norfloxacin decreases bacterial adherence of quinolone-resistant strains of Escherichia coli isolated from patients with cirrhosis

scientific article

Norfloxacin modulates the inflammatory response and directly affects neutrophils in patients with decompensated cirrhosis

scientific article published on 4 August 2009

Novel antimigraineur dotarizine releases Ca2+ from caffeine-sensitive Ca2+ stores of chromaffin cells

scientific article published on October 1999

Perineal body anatomy seen by three-dimensional endovaginal ultrasound of asymptomatic nulliparae

scientific article published on 01 April 2016

Peripheral neuropathy predicts nuclear gene defect in patients with mitochondrial ophthalmoplegia

scientific article

Peritoneal macrophage priming in cirrhosis is related to ERK phosphorylation and IL-6 secretion

scientific article published on 19 August 2010

Pharmacogenetic relevance of the CYP2C9*3 allele in a tenoxicam bioequivalence study performed on Spaniards.

scientific article

Pharmacokinetic variations of acetaminophen according to liver dysfunction and portal hypertension status

scientific article

Presence of bacterial-DNA in cirrhosis identifies a subgroup of patients with marked inflammatory response not related to endotoxin

scientific article published on 22 October 2007

Protective effect of Bifidobacterium pseudocatenulatum CECT7765 against induced bacterial antigen translocation in experimental cirrhosis.

scientific article published on 24 November 2013

Proteomic evidence of bacterial peptide translocation in afebrile patients with cirrhosis and ascites

scientific article published on 20 January 2010

Regulatory T Cells Restrict Permeability to Bacterial Antigen Translocation and Preserve Short-Chain Fatty Acids in Experimental Cirrhosis

scientific article published on 22 October 2018

Response to "Diagnosis of exocrine pancreatic insufficiency in chronic pancreatitis: 13C-mixed Triglyceride Breath Test versus Fecal Elastase: Methodological issues".

scientific article published on 22 May 2017

Risk of Cancer in Family Members of Patients with Lynch-Like Syndrome

scientific article published on 09 August 2020

Risk of cancer in cases of suspected lynch syndrome without germline mutation.

scientific article published on 24 January 2013

Role of interleukin 10 in norfloxacin prevention of luminal free endotoxin translocation in mice with cirrhosis.

scientific article

Selective intestinal decontamination with norfloxacin enhances a regulatory T cell-mediated inflammatory control mechanism in cirrhosis.

scientific article published on 23 May 2016

Serum and ascitic fluid bacterial DNA: a new independent prognostic factor in noninfected patients with cirrhosis

scientific article published on 01 December 2008

The detection of bacterial DNA in blood of rats with CCl4-induced cirrhosis with ascites represents episodes of bacterial translocation.

scientific article

The diagnosis of drug-induced liver disease.

scientific article published on May 2006

The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status.

scientific article published on 21 August 2008

The existence of a relationship between increased serum alanine aminotransferase levels detected in premarketing clinical trials and postmarketing published hepatotoxicity case reports.

scientific article published on 13 March 2010

The expression and activation of the AIM2 inflammasome correlates with inflammation and disease severity in patients with acute pancreatitis.

scientific article published on 18 March 2017

The use of β-blockers is associated with a lower risk of developing hepatocellular carcinoma in patients with cirrhosis.

scientific article published on 10 June 2016

Tobramycin penetration into epithelial lining fluid of patients with pneumonia

scientific article published on 01 March 1999

Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis.

scientific article

Translocation of bacterial DNA from Gram-positive microorganisms is associated with a species-specific inflammatory response in serum and ascitic fluid of patients with cirrhosis

scientific article published on 05 September 2007

Treatment with non-selective beta-blockers affects the systemic inflammatory response to bacterial DNA in patients with cirrhosis

scientific article published on 19 June 2018

Tumor necrosis factor-alpha, interleukin-6, and nitric oxide in sterile ascitic fluid and serum from patients with cirrhosis who subsequently develop ascitic fluid infection

article

Update of the Atlanta Classification of severity of acute pancreatitis: should a moderate category be included?

scientific article published on 30 October 2010

Use of proton pump inhibitors decrease cellular oxidative burst in patients with decompensated cirrhosis

scientific article published in January 2015

Usefulness of surveillance programmes for early diagnosis of hepatocellular carcinoma in clinical practice

scientific article published on 01 May 2008

Variations of pharmacokinetics of drugs in patients with cirrhosis

scientific article published on 23 December 2015

[Assessment of the surgical risk of 1,000 consecutive episodes using the POSSUM system. Comparison between elective and emergency gastrointestinal surgery]

scientific article published on 03 September 2011

aLicante sUrgical Community Emergencies New Tool for the enUmeration of Morbidities: a simplified auditing tool for community-acquired gastrointestinal surgical emergencies.

scientific article published on 7 May 2016