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List of works by Hiroaki Adachi

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

scientific article published on 11 September 2005

17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse

scientific article

A case of Parkinson's disease following dystonia.

scientific article

A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity

scientific article published in May 2015

Androgen-dependent loss of muscle BDNF mRNA in two mouse models of SBMA.

scientific article published on 27 April 2015

Anti-androgen therapy for spinal and bulbar muscular atrophy (SBMA)

scientific article published on 01 January 2012

Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy.

scientific article

Axonal loss influences the response to rituximab treatment in neuropathy associated with IgM monoclonal gammopathy with anti-myelin-associated glycoprotein antibody

scientific article published on 13 November 2014

BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1.

scientific article published on 4 April 2016

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.

scientific article published in May 2007

Cerebrotendinous Xanthomatosis with Nodular-hypertrophy of the Lumbosacral Roots

scientific article published on 11 January 2018

Classic polyarteritis nodosa presenting rare clinical manifestations in a patient with hemophilia A.

scientific article published in June 2006

Clinicopathological features of acute autonomic and sensory neuropathy

scientific article published on 23 August 2010

Clinicopathological features of neuropathy associated with lymphoma

scientific article published on 01 August 2013

Coexisting infectious diseases on admission as a risk factor for mechanical ventilation in patients with Guillain-Barré syndrome.

scientific article

Contractile dysfunction in muscle may underlie androgen-dependent motor dysfunction in spinal bulbar muscular atrophy.

scientific article

Cortical and subcortical brain atrophy in Parkinson's disease with visual hallucination.

scientific article published on 21 October 2013

Current status of treatment of spinal and bulbar muscular atrophy.

scientific article

DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes5

scientific article published on 01 May 2019

Defects in Neuromuscular Transmission May Underlie Motor Dysfunction in Spinal and Bulbar Muscular Atrophy

scientific article published on May 2016

Detecting a long insertion variant in SAMD12 by SMRT sequencing: implications of long-read whole-genome sequencing for repeat expansion diseases

scientific article published on 17 December 2018

Detection of dentate nuclei abnormality in a patient with dentatorubral-pallidoluysian atrophy using the quantitative susceptibility mapping

scientific article published on 18 June 2019

Development of the treatment for bulbospinal muscular atrophy

scientific article published on 01 July 2004

Direct Gram staining of blood culture sample enabled the early diagnosis of brain abscess due to Listeria monocytogenes

scientific article published on November 1999

Disease Affects Expression in Synaptic and Extrasynaptic Regions of Skeletal Muscle of Three SBMA Mouse Models ⬇️

scientific article published on 15 March 2019

Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.

scientific article published on April 2010

Distinct acoustic features in spinal and bulbar muscular atrophy patients with laryngospasm

scientific article published on 11 December 2013

Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 01 January 2010

Evoked potentials are useful for diagnosis of neuromyelitis optica spectrum disorder

scientific article published on 27 February 2016

Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis

scientific article published on 01 July 2007

Genetic evidence for a protective role for heat shock factor 1 and heat shock protein 70 against colitis

scientific article published on 07 June 2007

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease

scientific article published on 27 February 2013

Getting a handle on Huntington's disease: the case for cholesterol

scientific article published in March 2009

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HSP70 confers protection against indomethacin-induced lesions of the small intestine.

scientific article

Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration

scientific article

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein

scientific article published on 01 March 2003

Heat shock proteins in neurodegenerative diseases: pathogenic roles and therapeutic implications

scientific article published in December 2009

Hsp105alpha suppresses the aggregation of truncated androgen receptor with expanded CAG repeats and cell toxicity

scientific article published on 24 April 2003

Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy

scientific article published on 23 June 2016

In vivo phosphorylation of WRKY transcription factor by MAPK.

scientific article

Increased expression level of Hsp70 in the inner ears of mice by exposure to low frequency noise

scientific article published on 24 February 2018

Juxtacortical Lesions in Multiple Sclerosis: Assessment of Gray Matter Involvement Using Phase Difference-enhanced Imaging (PADRE).

scientific article published on 3 February 2016

Kinase-mediated orchestration of NADPH oxidase in plant immunity.

scientific article

Late-onset Myasthenia Gravis Accompanied by Amyotrophic Lateral Sclerosis with Antibodies against the Acetylcholine Receptor and Low-density Lipoprotein Receptor-related Protein 4

scientific article published on 15 October 2018

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

scientific article published on 18 May 2003

Macroautophagy is regulated by the UPR-mediator CHOP and accentuates the phenotype of SBMA mice

scientific article

Microarray analysis of gene expression by skeletal muscle of three mouse models of Kennedy disease/spinal bulbar muscular atrophy

scientific article

Molecular Genetics and Biomarkers of Polyglutamine Diseases

scientific article

Molecular pathophysiology and disease-modifying therapies for spinal and bulbar muscular atrophy

scientific article published on 12 December 2011

Molecular-targeted therapies for spinal and bulbar muscular atrophy

scientific article published in November 2009

Molecular-targeted therapy for motor neuron disease

scientific article published in August 2009

Muscle BDNF improves synaptic and contractile muscle strength in Kennedy's disease mice in a muscle-type specific manner

scientific article published on 19 April 2020

Muscle atrophy in chronic inflammatory demyelinating polyneuropathy: a computed tomography assessment.

scientific article published on 29 March 2014

Mutant androgen receptor accumulation in spinal and bulbar muscular atrophy scrotal skin: a pathogenic marker

scientific article published in March 2006

Myoclonia continua in primary CNS natural killer/T-cell lymphoma, nasal type

scientific article published on 07 December 2016

Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract.

scientific article

Natural Compounds Preventing Neurodegenerative Diseases Through Autophagic Activation

scientific article

Neural correlates of body comparison and weight estimation in weight-recovered anorexia nervosa: a functional magnetic resonance imaging study

scholarly article by Naoki Kodama et al published 2018 in BioPsychoSocial Medicine

Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration

scientific article published on 07 November 2015

Paeoniflorin eliminates a mutant AR via NF-YA-dependent proteolysis in spinal and bulbar muscular atrophy

scientific article published on 18 February 2014

Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy.

scientific article published on April 2007

Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA).

scientific article published on 15 May 2012

Pathogenesis, animal models and therapeutics in spinal and bulbar muscular atrophy (SBMA).

scientific article

Pioglitazone suppresses neuronal and muscular degeneration caused by polyglutamine-expanded androgen receptors

scientific article published on 28 August 2014

Potential of a new MRI for visualizing cerebellar involvement in progressive supranuclear palsy.

scientific article published on 16 October 2013

Potential usefulness of signal intensity of cerebral gyri on quantitative susceptibility mapping for discriminating corticobasal degeneration from progressive supranuclear palsy and Parkinson's disease

scientific article published on 02 July 2019

Pre-clinical symptoms of SBMA may not be androgen-dependent: implications from two SBMA mouse models

scientific article published on 01 July 2018

Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration.

scientific article published in November 2006

Silencing neuronal mutant androgen receptor in a mouse model of spinal and bulbar muscular atrophy.

scientific article published on 30 July 2015

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

scientific article published on 21 April 2004

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy

scientific article published on 19 September 2019

Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.

scientific article published in April 2011

Suppression of UV-induced wrinkle formation by induction of HSP70 expression in mice

scientific article

Sweet relief for Huntington disease

scientific article published in February 2004

Systemic overexpression of SQSTM1/p62 accelerates disease onset in a SOD1H46R-expressing ALS mouse model.

scientific article published on 29 May 2018

TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases

scientific article

TGF-beta signaling in neurodegenerative diseases

scientific article published in November 2011

Tandem-genotypes: robust detection of tandem repeat expansions from long DNA reads

scientific article published on 19 March 2019

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

scientific article published in August 2002

The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease

scientific article published in May 2016

The enhancement of protein degradation systems exerts therapeutic effects in the polyglutamine-mediated motor neuron disease ⬇️

scientific article published on 01 November 2011

The facial nerve atrophy with spinal and bulbar muscular atrophy patients (SBMA): Three case reports with 3D fast imaging employing steady-state acquisition (FIESTA)

scientific article published on 12 September 2019

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy

scientific article published on 22 October 2013

Transforming Growth Factor-β Signaling in Motor Neuron Diseases ⬇️

scientific article published on February 1, 2011

Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death

scientific article

Transgenic mouse models of spinal and bulbar muscular atrophy (SBMA).

scientific article published on January 2003

Treatment of spinal and bulbar muscular atrophy

scientific article published in September 2004

Understanding of polyglutamine diseases through transgenic mouse models

scientific article

Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2

scientific article published on 01 July 2012

WRKY Transcription Factors Phosphorylated by MAPK Regulate a Plant Immune NADPH Oxidase in Nicotiana benthamiana.

scientific article published on 15 September 2015

Widespread nuclear and cytoplasmic accumulation of mutant androgen receptor in SBMA patients

scientific article published on 19 January 2005

Zebra sign of precentral gyri in amyotrophic lateral sclerosis: A novel finding using phase difference enhanced (PADRE) imaging-initial results

scientific article published on 28 January 2016

[109th Scientific Meeting of the Japanese Society of Internal Medicine: symposium: 2. Translational research and evidence-based medicine (EBM) in internal medicine in Japan, translational research; 1) Translational research on neurodegenerative dise

scientific article published on 01 September 2012

[Acute sensory neuropathy]

scientific article published on 01 January 1999

[Disease-modifying therapy for spinal and bulbar muscular atrophy (SBMA)]

scientific article published on 01 March 2012

c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis

scientific article

c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line

scientific article published on December 2002

p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.

scientific article published in May 2013

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