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List of works by Patrick Emond

(E)-[125I]-5-AOIBV: a SPECT radioligand for the vesicular acetylcholine transporter.

scientific article published on 19 September 2007

1H-13C NMR-based urine metabolic profiling in autism spectrum disorders.

scientific article published on 9 April 2013

1H-NMR-based metabolomic profiling of CSF in early amyotrophic lateral sclerosis

scientific article

3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT).

scientific article

A Multiplatform Metabolomics Approach to Characterize Plasma Levels of Phenylalanine and Tyrosine in Phenylketonuria.

scientific article published on 15 June 2016

A multiplatform metabolomic approach to characterize fecal signatures of negative postnatal events in chicks: a pilot study

scientific article published on 09 April 2019

A radiometabolite study of the serotonin transporter PET radioligand [(11)C]MADAM.

scientific article

A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: pharmacological evaluation and PET experiments.

scientific article published in January 1999

ADAM is an effective tool for in vivo study of serotonergic function: validation in rat models.

scientific article published in May 2004

ATP-activated P2X7 receptor in the pathophysiology of mood disorders and as an emerging target for the development of novel antidepressant therapeutics. ⬇️

scientific article published on 14 February 2018

Acetylenic pyridines for use in PET imaging of nicotinic receptors.

scientific article published in January 2007

An UPLC-MSMS method to measure plasma homocysteine concentration.

scientific article published in June 2017

Analytical methodology for metabolomics study of adherent mammalian cells using NMR, GC-MS and LC-HRMS.

scientific article published on 7 October 2015

Assessing the metabolic effects of calcineurin inhibitors in renal transplant recipients by urine metabolic profiling

scientific article published on 01 July 2014

Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice

scientific article published on 17 November 2018

Biomarkers in amyotrophic lateral sclerosis: combining metabolomic and clinical parameters to define disease progression.

scientific article published on 28 October 2015

Combined 1H-NMR and 1H-13C HSQC-NMR to improve urinary screening in autism spectrum disorders

scientific article published in July 2014

Comparative analysis of targeted metabolomics: dominance-based rough set approach versus orthogonal partial least square-discriminant analysis

scientific article published on 11 December 2014

Correction: 1H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis.

scientific article published on 10 November 2010

Correction: Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined 1H NMR and GC-MS approach.

scientific article published on 19 January 2017

Design of selective COX-2 inhibitors in the (aza)indazole series. Chemistry, in vitro studies, radiochemistry and evaluations in rats of a [F] PET tracer

scholarly article by Jonathan Elie et al published December 2019 in Journal of Enzyme Inhibition and Medicinal Chemistry

Disruption of TCA Cycle and Glutamate Metabolism Identified by Metabolomics in an In Vitro Model of Amyotrophic Lateral Sclerosis

scientific article published on 14 December 2015

Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imaging

scientific article published on 6 August 2008

Does lipidomic serum analysis support the assessment of digestive efficiency in chickens?

scientific article published in March 2019

Endogenous metabolites that are substrates of organic anion transporter's (OATs) predict methotrexate clearance.

scientific article

Erratum to "Validation of amino-acids measurement in dried blood spot by FIA-MS/MS for PKU management" [Clin. Biochem. 49 (2016) 1047-1050]

scientific article published on 02 May 2017

Ex vivo and in vivo evaluation of (2R,3R)-5-[(18)F]-fluoroethoxy- and fluoropropoxy-benzovesamicol, as PET radioligands for the vesicular acetylcholine transporter

scientific article published on 01 December 2007

Exploration of the dopamine transporter: in vitro and in vivo characterization of a high-affinity and high-specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-m ethylph enyl)nortropane (PE2I).

scientific article published in May 1998

Extensive exploration of a novel rat model of Parkinson's disease using partial 6-hydroxydopamine lesion of dopaminergic neurons suggests new therapeutic approaches

scientific article published on 12 November 2018

Fragmentation pathway of dopamine transporter ligands: N-substituted-2beta-carbomethoxy-3beta-phenylnortropane derivatives

scientific article published in April 2004

GC-MS-based urine metabolic profiling of autism spectrum disorders.

scientific article published on 10 April 2013

Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes

scientific article published on 12 July 2018

Hyperphenylalaninemia Correlated with Global Decrease of Antioxidant Genes Expression in White Blood Cells of Adult Patients with Phenylketonuria.

scientific article published on 15 March 2017

Identification of metabolic pathway disturbances using multimodal metabolomics in autistic disorders in a Middle Eastern population

scientific article published on 29 January 2018

Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates

scientific article published on 15 July 2011

Is NMR metabolic profiling of spent embryo culture media useful to assist in vitro human embryo selection?

scientific article published on 10 August 2012

Metabolomics Study of Urine in Autism Spectrum Disorders Using a Multiplatform Analytical Methodology

scientific article published on 5 November 2015

Metabolomics in Cerebrospinal Fluid of Patients with Amyotrophic Lateral Sclerosis: An Untargeted Approach via High-Resolution Mass Spectrometry

Microbiota tryptophan metabolism induces aryl hydrocarbon receptor activation and improves alcohol-induced liver injury

scientific article published on 01 October 2020

Neuroprotective effect of the alpha 7 nicotinic receptor agonist PHA 543613 in an in vivo excitotoxic adult rat model

scientific article

New fluoro-diphenylchalcogen derivatives to explore the serotonin transporter by PET.

scientific article published on 7 March 2007

PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter

scientific article published in August 2002

PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter

scientific article published in July 1999

Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging

scientific article published in May 1998

Pharmacological characterisation of (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-methylphenyl)nortropane (PE2I) binding to the rat neuronal dopamine transporter expressed in COS cells

scientific article published in February 2002

Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.

scientific article published on January 2003

Prenatal exposure to methylphenidate affects the dopamine system and the reactivity to natural reward in adulthood in rats

scientific article

QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT).

scientific article

Relationship between Metabolomics Profile of Perilymph in Cochlear-Implanted Patients and Duration of Hearing Loss

scientific article published on 01 November 2019

Single nucleotide polymorphisms of ABCC2 modulate renal secretion of endogenous organic anions.

scientific article published on 19 May 2017

Specific Metabolome Profile of Exhaled Breath Condensate in Patients with Shock and Respiratory Failure: A Pilot Study.

scientific article published on September 2016

Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.

scientific article published in March 2002

Synthesis and biological evaluation of a series of flavone derivatives as potential radioligands for imaging the multidrug resistance-associated protein 1 (ABCC1/MRP1).

scientific article published on 2 November 2005

Synthesis and biological evaluation of halogenated naphthyridone carboxamides as potential ligands for in vivo imaging studies of substance P receptors

scientific article published in May 2003

Synthesis and evaluation of iodine-123 labelled tricyclic tropanes as radioligands for the serotonin transporter

scientific article published in October 2003

Synthesis and in vitro evaluation of N-substituted aza-trozamicol analogs as vesicular acetylcholine transporter ligands.

scientific article published on 3 March 2006

Synthesis and in vitro evaluation of fluorinated diphenyloxide derivatives and sulfur analogs as serotonin transporter ligands.

scientific article

Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter

scientific article published in February 2005

Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands.

scientific article

Synthesis and ligand binding of nortropane derivatives: N-substituted 2beta-carbomethoxy-3beta-(4'-iodophenyl)nortropane and N-(3-iodoprop-(2E)-enyl)-2beta-carbomethoxy-3beta-(3',4'-disubstituted phenyl)nortropane. New high-affinity and selective co

scientific article published in April 1997

Synthesis of tropane and nortropane analogues with phenyl substitutions as serotonin transporter ligands.

scientific article

Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter

scientific article published in December 2002

Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET.

scientific article

The Metabolic Disturbances of Motoneurons Exposed to Glutamate.

scientific article published on 12 February 2018

The combination of four analytical methods to explore skeletal muscle metabolomics: Better coverage of metabolic pathways or a marketing argument?

scientific article published on 18 October 2017

Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT.

scientific article published in May 1998

Trough infliximab concentrations predict efficacy and sustained control of disease activity in rheumatoid arthritis

scientific article published on 01 April 2010

Untargeted 1H-NMR metabolomics in CSF: toward a diagnostic biomarker for motor neuron disease

scientific article published on 28 February 2014

Validation of a global quantitative analysis methodology of tryptophan metabolites in mice using LC-MS

scientific article published on 27 November 2018

Validation of amino-acids measurement in dried blood spot by FIA-MS/MS for PKU management.

scientific article published on 20 July 2016

Validation of metabolomics analysis of human perilymph fluid using liquid chromatography-mass spectroscopy

scientific article published on 22 May 2018

Visualization of the dopamine transporter in the human brain postmortem with the new selective ligand [125I]PE2I.

scientific article

Whole-body distribution and radiation dosimetry of the dopamine transporter radioligand [(11)C]PE2I in healthy volunteers

scientific article

Wildtype motoneurons, ALS-Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling.

scientific article published on 31 January 2017

Workflow methodology for rat brain metabolome exploration using NMR, LC-MS and GC-MS analytical platforms

scientific article published on 13 May 2017

[(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET.

scientific article published in December 2005

[(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain

scientific article

[Investigation of hyperhomocysteinemia].

scientific article

[Mass spectrometry for steroid assays]

scientific article published on 01 January 2015

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