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List of works by Nikolaos E. Labrou

2,2'-Dihydroxybenzophenones and their carbonyl N-analogues as inhibitor scaffolds for MDR-involved human glutathione transferase isoenzyme A1-1.

scientific article

A Batch Test Tube Method for the Calculation of an Adsorbent's Available Capacity

scientific article published on 01 June 2006

A Glutathione Transferase from Agrobacterium tumefaciens Reveals a Novel Class of Bacterial GST Superfamily ⬇️

scientific article published on April 4, 2012

A new colorimetric assay for glutathione transferase-catalyzed halogen ion release for high-throughput screening

scientific article

Active-site characterization of Candida boidinii formate dehydrogenase

scientific article

Affinity chromatography for the purification of therapeutic proteins from transgenic maize using immobilized histamine

scientific article

Affinity labeling of oxaloacetate decarboxylase by novel dichlorotriazine linked alpha-ketoacids

scientific article published on 01 October 1999

Application of a PEG/salt aqueous two-phase partition system for the recovery of monoclonal antibodies from unclarified transgenic tobacco extract

scientific article published on 01 September 2009

Biochemical characterization and immobilization of Erwinia carotovoral-asparaginase in a microplate for high-throughput biosensing of l-asparagine

scientific article published on 28 June 2016

Biomimetic dye affinity chromatography for the purification of bovine heart lactate dehydrogenase

scientific article published in December 1995

Biomimetic-dye affinity adsorbents for enzyme purification: application to the one-step purification of Candida boidinii formate dehydrogenase.

scientific article published in November 1995

Biomimetic-dye affinity chromatography for the purification of mitochondrial L-malate dehydrogenase from bovine heart

scientific article published in March 1996

Catalytic and structural diversity of the fluazifop-inducible glutathione transferases from Phaseolus vulgaris

scientific article published on 28 December 2011

Catalytic features and crystal structure of a tau class glutathione transferase from Glycine max specifically upregulated in response to soybean mosaic virus infections

scientific article

Characterization and functional analysis of a recombinant tau class glutathione transferase GmGSTU2-2 from Glycine max.

scientific article

Characterization of the NAD+ binding site of Candida boidinii formate dehydrogenase by affinity labelling and site-directed mutagenesis

scientific article published on 01 November 2000

Characterization of the ligandin site of maize glutathione S-transferase I.

scientific article

Characterization of two novel nodule-enhanced α-type carbonic anhydrases from Lotus japonicus.

scientific article

Chemical and genetic engineering strategies to improve the potency of pharmaceutical proteins and enzymes

scientific article

Cloning and characterization of Lotus japonicus formate dehydrogenase: a possible correlation with hypoxia

scientific article published on 10 March 2009

Cloning and characterization of a biotic-stress-inducible glutathione transferase from Phaseolus vulgaris

scientific article published on 9 October 2013

Cloning, expression and characterisation of Erwinia carotovora L-asparaginase.

scientific article

Combinatorial de novo design and application of a biomimetic affinity ligand for the purification of human anti-HIV mAb 4E10 from transgenic tobacco.

scientific article

Cost-effective production of a vaginal protein microbicide to prevent HIV transmission.

scholarly article

Crystal structure of Glycine max glutathione transferase in complex with glutathione: investigation of the mechanism operating by the Tau class glutathione transferases.

scientific article

Crystallographic and functional characterization of the fluorodifen-inducible glutathione transferase from Glycine max reveals an active site topography suited for diphenylether herbicides and a novel L-site

scientific article

Cytochrome P450 102A2 Catalyzes Efficient Oxidation of Sodium Dodecyl Sulphate: A Molecular Tool for Remediation

scientific article

Delineation of the functional and structural properties of the glutathione transferase family from the plant pathogen Erwinia carotovora

scientific article published on 25 June 2018

Design, synthesis and application of benzyl-sulfonate biomimetic affinity adsorbents for monoclonal antibody purification from transgenic corn.

scientific article

Designer xanthone: an inhibitor scaffold for MDR-involved human glutathione transferase isoenzyme A1-1.

scientific article published on 7 June 2013

Development of Staphylococcus Enzybiotics: The Ph28 Gene of Staphylococcus epidermidis Phage PH15 Is a Two-Domain Endolysin

scientific article published on 30 March 2020

Development of a colourimetric pH assay for the quantification of pyrethroids based on glutathione-S-transferase

article

Development of an aqueous two-phase partitioning system for fractionating therapeutic proteins from tobacco extract

scientific article

Development of recombinant protein-based influenza vaccine. Expression and affinity purification of H1N1 influenza virus neuraminidase

scientific article

Development of transgenic tobacco plants overexpressing maize glutathione S-transferase I for chloroacetanilide herbicides phytoremediation

scientific article published in October 2005

Directed evolution of Tau class glutathione transferases reveals a site that regulates catalytic efficiency and masks co-operativity

scientific article

Directed evolution of glutathione transferases towards a selective glutathione-binding site and improved oxidative stability

scientific article

Dye affinity labelling of yeast alcohol dehydrogenase

scientific article published in January 2000

Dye-affinity labelling of bovine heart mitochondrial malate dehydrogenase and study of the NADH-binding site

scientific article published on April 1996

Effect of soya bean and fish oil inclusion in diets on milk and plasma enzymes from sheep and goat related to oxidation

scientific article published on 3 April 2016

Engineering sensitive glutathione transferase for the detection of xenobiotics.

scientific article published on 4 July 2008

Engineering the pH-dependence of kinetic parameters of maize glutathione S-transferase I by site-directed mutagenesis

scientific article published in April 2004

Engineering the substrate specificity of cytochrome P450 CYP102A2 by directed evolution: production of an efficient enzyme for bioconversion of fine chemicals.

scientific article

Engineering the xenobiotic substrate specificity of maize glutathione S-transferase I.

scientific article published in October 2004

Engineering thermal stability of L-asparaginase by in vitro directed evolution

scientific article

Functional characterization of glutathione S-transferases associated with insecticide resistance in Tetranychus urticae

scientific article published on 23 January 2015

Genetic diversity and structure of Rhizobium leguminosarum populations associated with clover plants are influenced by local environmental variables

scientific article published on 3 February 2018

Glutathione analogues as substrates or inhibitors that discriminate between allozymes of the MDR-involved human glutathione transferase P1-1.

scientific article

Glutathione transferases: emerging multidisciplinary tools in red and green biotechnology.

scientific article

Improved purification of Candida boidinii formate dehydrogenase

scientific article published in January 2000

Inhibition Analysis and High-Resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1 ⬇️

scientific article published on 29 March 2023

Insights into the Influence of Specific Splicing Events on the Structural Organization of

scholarly article by Dimitrios Vlachakis published in September 2018

Interaction of L-glutamate oxidase with triazine dyes: selection of ligands for affinity chromatography.

scientific article published in August 2004

Interaction of Met297 in the seventh transmembrane segment of the tachykinin NK2 receptor with neurokinin A.

scientific article

Investigation of the role of conserved residues Ser13, Asn48 and Pro49 in the catalytic mechanism of the tau class glutathione transferase from Glycine max.

scientific article published on 29 October 2009

Isoenzyme- and allozyme-specific inhibitors: 2,2'-dihydroxybenzophenones and their carbonyl N-analogues that discriminate between human glutathione transferase A1-1 and P1-1 allozymes.

scientific article

Kinetic analysis of maize glutathione S-transferase I catalysing the detoxification from chloroacetanilide herbicides

scientific article published on 20 May 2005

L-Asparaginase from Erwinia Chrysanthemi 3937: cloning, expression and characterization.

scientific article

L-Malate dehydrogenase from Pseudomonas stutzeri: purification and characterization

scientific article published in January 1997

Lock-and-key motif as a concept for designing affinity adsorbents for protein purification

scientific article

Molecular and biochemical characterization of the parvulin-type PPIases in Lotus japonicus.

scientific article published on 29 April 2009

Molecular characterization, fitness and mycotoxin production of Fusarium graminearum laboratory strains resistant to benzimidazoles

scientific article published on 9 October 2015

Molecular modeling for the design of a biomimetic chimeric ligand. Application to the purification of bovine heart L-lactate dehydrogenase

scientific article published in May 1999

Molecular modelling for the design of chimaeric biomimetic dye-ligands and their interaction with bovine heart mitochondrial malate dehydrogenase

scientific article published on April 1996

Monomeric Camelus dromedarius GSTM1 at low pH is structurally more thermostable than its native dimeric form

scientific article published in PLoS ONE

New downstream processing strategy for the purification of monoclonal antibodies from transgenic tobacco plants

scientific article published on 04 October 2008

Nucleotide-mimetic synthetic ligands for DNA-recognizing enzymes One-step purification of Pfu DNA polymerase.

scientific article

One-step purification of Taq DNA polymerase using nucleotide-mimetic affinity chromatography

scientific article

Optimization of adsorption conditions for dye-ligand affinity chromatography

scientific article published on 01 June 2006

Optimization of elution conditions for dye-ligand affinity chromatography

scientific article published on 01 June 2006

Overexpression of a specific soybean GmGSTU4 isoenzyme improves diphenyl ether and chloroacetanilide herbicide tolerance of transgenic tobacco plants.

scientific article

Overlapping protective roles for glutathione transferase gene family members in chemical and oxidative stress response in Agrobacterium tumefaciens

scientific article

Oxaloacetate decarboxylase from Pseudomonas stutzeri: purification and characterization

scientific article published on 01 May 1999

Oxaloacetate decarboxylase: on the mode of interaction with substrate-mimetic affinity ligands

scientific article published in August 1995

Plant GSTome: structure and functional role in xenome network and plant stress response.

scientific article

Preparation of affinity-ligand resins by immobilization of dyes on polyhydroxyl matrices using a spacer arm

scientific article published on 01 June 2006

Protein purification: an overview.

scientific article published on January 2014

Purification of M-MLVH- RT on a 9-aminoethyladenine-(1,6-diamine-hexane)-triazine selected from a combinatorial library of dNTP-mimetic ligands.

scientific article

Purification of protein using dye-ligand affinity chromatography

scientific article published on 01 June 2006

Random mutagenesis methods for in vitro directed enzyme evolution

scientific article

Recent advances in protein engineering and biotechnological applications of glutathione transferases

scientific article published on 22 September 2017

Reduce, Reuse and Recycle in Protein Chromatography: Development of an Affinity Adsorbent from Waste Paper and Its Application for the Purification of Proteases from Fish By-Products

scientific article published on 27 May 2020

S-(2,3-dichlorotriazinyl)glutathione. A new affinity label for probing the structure and function of glutathione transferases

scientific article

Screening Immobilized Dyes for their Ability to Bind a Target Protein

scientific article published on 01 June 2006

Site-saturation mutagenesis: a powerful tool for structure-based design of combinatorial mutation libraries.

scientific article

Structural and functional role of Gly281 in L-asparaginase from Erwinia carotovora.

scientific article

Structural and thermodynamic properties of kappa class glutathione transferase from Camelus dromedarius.

scientific article published on April 2016

Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding

scientific article published on 19 August 2006

Structure-activity studies on cysteine-substituted neurokinin A analogs

scientific article published on January 1999

Structure-guided alteration of coenzyme specificity of formate dehydrogenase by saturation mutagenesis to enable efficient utilization of NADP+.

scientific article

Structure-guided design of a novel class of benzyl-sulfonate inhibitors for influenza virus neuraminidase

scientific article

Sulphonamide-based bombesin prodrug analogues for glutathione transferase, useful in targeted cancer chemotherapy.

scientific article published on 17 October 2008

Synthesis and application of dye-ligand affinity adsorbents

scientific article published in January 2014

Synthesis and study of 2-(pyrrolesulfonylmethyl)-N-arylimines: a new class of inhibitors for human glutathione transferase A1-1

scientific article published on 31 July 2012

Tailoring structure-function properties of L-asparaginase: engineering resistance to trypsin cleavage

scientific article

The affinity technology in downstream processing

scientific article published on August 1994

The conserved Asn49 of maize glutathione S-transferase I modulates substrate binding, catalysis and intersubunit communication

scientific article published in July 2001

The interaction of Candida boidinii formate dehydrogenase with a new family of chimeric biomimetic dye-ligands.

scientific article published on January 1995

The interaction of Schistosoma japonicum glutathione transferase with Cibacron blue 3GA and its fragments

scientific article published on 02 April 2020

The interaction of the chemotherapeutic drug chlorambucil with human glutathione transferase A1-1: kinetic and structural analysis

scientific article

The structure-function relationship in the clostripain family of peptidases

scientific article published in March 2004

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