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List of works by Andrzej Slominski

1α,20S-Dihydroxyvitamin D3 Interacts with Vitamin D Receptor: Crystal Structure and Route of Chemical Synthesis

scientific article published on 31 August 2017

20,23-dihydroxyvitamin D3, novel P450scc product, stimulates differentiation and inhibits proliferation and NF-kappaB activity in human keratinocytes

scientific article published on April 2010

20-Hydroxycholecalciferol, product of vitamin D3 hydroxylation by P450scc, decreases NF-kappaB activity by increasing IkappaB alpha levels in human keratinocytes

scientific article

20-Hydroxyvitamin D2 is a noncalcemic analog of vitamin D with potent antiproliferative and prodifferentiation activities in normal and malignant cells

scientific article

20-Hydroxyvitamin D3, a product of vitamin D3 hydroxylation by cytochrome P450scc, stimulates keratinocyte differentiation

scientific article

20-hydroxyvitamin D₃ inhibits proliferation of cancer cells with high efficacy while being non-toxic

scientific article published on March 1, 2012

20S-hydroxyvitamin D3, noncalcemic product of CYP11A1 action on vitamin D3, exhibits potent antifibrogenic activity in vivo

scientific article published on 7 January 2013

A Proposed Molecular Mechanism of High-Dose Vitamin D3 Supplementation in Prevention and Treatment of Preeclampsia.

scientific article published on 9 June 2015

A new steroidal 5,7-diene derivative, 3beta-hydroxyandrosta-5,7-diene-17beta-carboxylic acid, shows potent anti-proliferative activity

scientific article

A novel metabolic pathway of melatonin: oxidation by cytochrome C.

scientific article published in July 2005

A novel microarray to evaluate stress-related genes in skin: effect of ultraviolet light radiation

scientific article published in October 2004

A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin

scientific article

A novel translational model of percutaneous fetoscopic endoluminal tracheal occlusion - baboons (Papio spp.).

scientific article published on 30 January 2014

ACTH receptor, CYP11A1, CYP17 and CYP21A2 genes are expressed in skin

scientific article published on 01 July 1996

Acquired primary cutaneous ganglioneuroma with adipocytic metaplasia: "An end point of melanocytic 'maturation'?" a case report and meta-analysis with comparison to a cross-sectional study of neurotized melanocytic nevi

scientific article published on 01 February 2011

Active steroidogenesis in the normal rat skin

scientific article published on 01 March 2000

An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2.

scientific article published on July 2006

Animals under the sun: effects of ultraviolet radiation on mammalian skin

scientific article published in July 1998

Antifibrogenic activities of CYP11A1-derived vitamin D3-hydroxyderivatives are dependent on RORγ

scientific article published on 27 October 2020

Antiproliferative Activity of Non-Calcemic Vitamin D Analogs on Human Melanoma Lines in Relation to VDR and PDIA3 Receptors

scholarly article by Tomasz Wasiewicz published in August 2018

Antitumor effects of vitamin D analogs on hamster and mouse melanoma cell lines in relation to melanin pigmentation

scientific article published on 24 March 2015

Are L-tyrosine and L-dopa hormone-like bioregulators?

scientific article published on March 1990

Are suberythemal doses of ultraviolet B good for your skin?

scientific article published on 17 January 2009

Assessment of Melatonin-Cultured Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials for Wound Healing

scientific article published on 17 March 2022

Association among Vitamin D, Retinoic Acid-Related Orphan Receptors, and Vitamin D Hydroxyderivatives in Ovarian Cancer

scientific article published on 19 November 2020

Beta-endorphin/mu-opiate receptor system in the skin

scientific article

Bioactive forms of vitamin D selectively stimulate the skin analog of the hypothalamus-pituitary-adrenal axis in human epidermal keratinocytes

scientific article published on 11 August 2016

Biochemical characterization of three hamster melanoma variants--I. Tyrosinase activity and melanin content

scientific article published on 01 January 1984

Biochemical characterization of three hamster melanoma variants--II. Glycolysis and oxygen consumption

scientific article published on 01 January 1984

Biomarkers in melanoma: predisposition, screening and diagnosis

scientific article

Biomarkers in melanoma: stage III and IV disease.

scientific article

Biomarkers in melanoma: staging, prognosis and detection of early metastases.

scientific article

COVID-19 and Vitamin D: A lesson from the skin

scientific article published on 11 August 2020

CRF1 receptor splicing in epidermal keratinocytes: potential biological role and environmental regulations

scientific article published on March 2009

CRH functions as a growth factor/cytokine in the skin

scientific article published on March 2006

CRH inhibits NF-kappa B signaling in human melanocytes.

scientific article published on 7 September 2006

CRH stimulates POMC activity and corticosterone production in dermal fibroblasts

scientific article published in May 2005

CRH stimulation of corticosteroids production in melanocytes is mediated by ACTH.

scientific article published on 30 November 2004

CYP24A1 expression inversely correlates with melanoma progression: clinic-pathological studies.

scientific article

Calcitriol and Calcidiol Can Sensitize Melanoma Cells to Low⁻LET Proton Beam Irradiation

scientific article published on 31 July 2018

Changes in Immunogenicity during the Development of Urinary Bladder Cancer: A Preliminary Study.

scientific article published on 25 February 2016

Characterization of a hamster melanoma-associated ganglioside antigen as 7-O-acetylated disialoganglioside GD3.

scientific article published in September 1993

Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols

scientific article published on 12 September 2017

Characterization of a ultraviolet B-induced corticotropin-releasing hormone-proopiomelanocortin system in human melanocytes

scientific article published on June 2006

Characterization of corticotropin-releasing hormone (CRH) in human skin

scientific article published on 01 March 1998

Characterization of serotonin and N-acetylserotonin systems in the human epidermis and skin cells

scientific article published on 20 December 2019

Characterization of the serotoninergic system in the C57BL/6 mouse skin.

scientific article published in August 2003

Chemical Synthesis and Biological Activities of 20S,24S/R-Dihydroxyvitamin D3 Epimers and Their 1α-Hydroxyl Derivatives.

scientific article

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity.

scientific article published on 11 June 2010

Choriocarcinoma presenting as a cutaneous metastasis

scientific article published on 01 August 1995

Classical and non-classical metabolic transformation of vitamin D in dermal fibroblasts

scientific article published on 6 October 2015

Clinical Trials for Use of Melatonin to Fight against COVID-19 Are Urgently Needed

scientific article published on 24 August 2020

Commentary on the practical guide for the study of sebaceous glands

scientific article (publication date: October 2013)

Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems

scientific article published on 22 June 2006

Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells

scientific article

Cooling skin cancer: menthol inhibits melanoma growth. Focus on "TRPM8 activation suppresses cellular viability in human melanoma".

scientific article published on August 2008

Correlation between secosteroid-induced vitamin D receptor activity in melanoma cells and computer-modeled receptor binding strength

scientific article published on 21 April 2012

Corrigendum to ‘A new slteroidal 5,7diene derivat ive, 3β-hydroxyandrosta-5,7-diene-17β-carboxylic acid, shows potent anti-proliferative activity’.

scientific article published in September 2010

Corticotropin releasing factor receptor type 1: molecular cloning and investigation of alternative splicing in the hamster skin

scientific article

Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

scientific article

Corticotropin releasing hormone and the skin

scientific article published on September 2006

Corticotropin-releasing hormone affects cytokine production in human HaCaT keratinocytes

scientific article published on January 2002

Corticotropin-releasing hormone induces keratinocyte differentiation in the adult human epidermis

scientific article published in April 2005

Corticotropin-releasing hormone inhibits nuclear factor-kappaB pathway in human HaCaT keratinocytes.

scientific article

Cultured human dermal fibroblasts do produce cortisol

scientific article

Current Molecular Markers of Melanoma and Treatment Targets

scientific article published on 16 May 2020

Current concepts of metastasis in melanoma.

scientific article

Cutaneous Immunomodulation and Coordination of Skin Stress Responses by α‐Melanocyte‐Stimulating Hormonea

scientific article published on May 1, 1998

Cutaneous expression of corticotropin-releasing hormone (CRH), urocortin, and CRH receptors

scientific article

Cutaneous glucocorticosteroidogenesis: securing local homeostasis and the skin integrity

scientific article

Cutaneous hypothalamic-pituitary-adrenal axis homolog: regulation by ultraviolet radiation

scientific article

Cutaneous melanoma: pathology, relevant prognostic indicators and progression.

scientific article published on July 1995

Cutaneous metabolism of vitamin B-6.

scientific article published on February 2003

Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes

scientific article published on August 2, 2012

Decreased expression of CYP27B1 correlates with the increased aggressiveness of ovarian carcinomas

scientific article

Dermatofibrosarcoma protuberans can induce epidermal hyperplasia that is inversely related to its proximity to the epidermis

scientific article published on 01 August 1998

Design, synthesis, and biological action of 20R-hydroxyvitamin D3.

scientific article published on 20 March 2012

Detection of 7-Dehydrocholesterol and Vitamin D3 Derivatives in Honey

scientific article published on 02 June 2020

Detection of Serotonin, Melatonin, and Their Metabolites in Honey

scientific article published on 20 August 2021

Detection of novel CYP11A1-derived secosteroids in the human epidermis and serum and pig adrenal gland.

scientific article

Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin.

scientific article published in December 1993

Developmentally regulated expression of alpha-MSH and MC-1 receptor in C57BL/6 mouse skin suggests functions beyond pigmentation.

scientific article published in October 1999

Differential Expression and Activity of Melanogenesis-Related Proteins During Induced Hair Growth in Mice

scientific article published on February 1, 1991

Differential and Overlapping Effects of 20,23(OH)₂D3 and 1,25(OH)₂D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)₂D3

article

Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture.

scientific article

Differential expression of HPA axis homolog in the skin

scientific article published on 29 December 2006

Differential expression of a cutaneous corticotropin-releasing hormone system

scientific article

Differentiation of Keratinocytes Modulates Skin HPA Analog

scientific article published on 6 April 2016

Disturbed expression of vitamin D and retinoic acid-related orphan receptors α and γ and of megalin in inflammatory skin diseases

scientific article published in May 2022

Does melanin matter in the dark?

scientific article published on 19 August 2016

Does p53 regulate skin pigmentation by controlling proopiomelanocortin gene transcription?

scientific article published on 01 August 2007

Down-regulation of the expression of O-acetyl-GD3 by the O-acetylesterase cDNA in hamster melanoma cells: effects on cellular proliferation, differentiation, and melanogenesis

scientific article

Effect of CRF and related peptides on calcium signaling in human and rodent melanoma cells

scientific article published on 01 September 1998

Effects of actinomycin D and cycloheximide on the increase in tyrosinase activity of hamster amelanotic melanoma cells in vitro

scientific article published on 01 December 1984

Effects of in utero exposure of C57BL/6J mice to 2,3,7,8-tetrachlorodibenzo-p-dioxin on epidermal permeability barrier development and function

scientific article

Effects of sidechain length and composition on the kinetic conversion and product distribution of vitamin D analogs determined by real-time NMR.

scientific article

Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity

scientific article published on 02 September 2013

Endogenously produced nonclassical vitamin D hydroxy-metabolites act as "biased" agonists on VDR and inverse agonists on RORα and RORγ.

scientific article published on 28 September 2016

Enzymatic metabolism of ergosterol by cytochrome p450scc to biologically active 17alpha,24-dihydroxyergosterol

scientific article published on August 2005

Epidermodysplasia verruciformis and cutaneous human papillomavirus DNA, but not genital human papillomavirus DNAs, are frequently detected in vulvar and vaginal melanoma

scientific article published in February 2007

Evaluation of Polymeric Matrix Loaded with Melatonin for Wound Dressing

scientific article

Experimental ruthenium plaque therapy of amelanotic and melanotic melanomas in the hamster eye

scientific article published on 01 February 2000

Expression of RCAS1 correlates with urothelial bladder cancer malignancy

scientific article

Expression of Vitamin D Receptor (VDR) Positively Correlates with Survival of Urothelial Bladder Cancer Patients

scientific article

Expression of antimicrobial peptide genes oscillates along day/night rhythm protecting mice skin from bacteria

scientific article published on 31 October 2020

Expression of genes coding melatonin and serotonin receptors in rodent skin

scientific article published in October 2004

Expression of hypothalamic-pituitary-thyroid axis related genes in the human skin

scientific article

Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patients

scientific article

Expression of the vitamin D-activating enzyme 1α-hydroxylase (CYP27B1) decreases during melanoma progression

scientific article

Expression of vitamin D receptor decreases during progression of pigmented skin lesions.

scientific article

Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders

scientific article published on 23 March 2020

Frequency of CD4+CD25+Foxp3+ cells in peripheral blood in relation to urinary bladder cancer malignancy indicators before and after surgical removal

scientific article published on 5 February 2016

Functional activity of serotoninergic and melatoninergic systems expressed in the skin

scientific article (publication date: July 2003)

Gas chromatography/mass spectrometry characterization of corticosteroid metabolism in human immortalized keratinocytes

scientific article published on February 2002

Genetic variation of the cutaneous HPA axis: an analysis of UVB-induced differential responses

scientific article published on 17 August 2013

Genomic Profiling of the Steroidogenic Acute Regulatory Protein in Breast Cancer: In Silico Assessments and a Mechanistic Perspective.

scientific article published on 4 May 2019

Giant Basal Cell Carcinomas Express Neuroactive Mediators and Show a High Growth Rate: A Case-Control Study and Meta-Analysis of Etiopathogenic and Prognostic Factors

scientific article

Glucocorticoids Inhibit Wound Healing: Novel Mechanism of Action.

scientific article published in May 2017

Hair cycle-dependent production of ACTH in mouse skin

scientific article

Hair follicle pigmentation

scientific article

High basal NF-κB activity in nonpigmented melanoma cells is associated with an enhanced sensitivity to vitamin D3 derivatives.

scientific article

Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.

scientific article published on 21 November 2011

Human female hair follicles are a direct, nonclassical target for thyroid-stimulating hormone

scientific article published on 4 December 2008

Human skin expresses growth hormone but not the prolactin gene.

scientific article

Hydroxylation of 20-hydroxyvitamin D3 by human CYP3A4.

scientific article published on 9 March 2016

Hydroxylation of CYP11A1-derived products of vitamin D3 metabolism by human and mouse CYP27B1.

scientific article published on March 2013

Hydroxylumisterols, Photoproducts of Pre-Vitamin D3, Protect Human Keratinocytes against UVB-Induced Damage

scientific article published on 09 December 2020

Identification and measurement of beta-endorphin levels in the skin during induced hair growth in mice.

scientific article

Immuno-histochemical evaluation of solar lentigines: The association of KGF/KGFR and other factors with lesion development.

scientific article published on 19 June 2010

In vivo evidence for a novel pathway of vitamin D 3 metabolism initiated by P450scc and modified by CYP27B1

scientific article published on June 8, 2012

In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland.

scientific article published on 29 December 2013

Inhibition of melanogenesis as a radiation sensitizer for melanoma therapy

scientific article

Inhibition of melanoma metastases by fenofibrate

scientific article

Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells

scientific article

Investigation of 20S-hydroxyvitamin D3 analogs and their 1α-OH derivatives as potent vitamin D receptor agonists with anti-inflammatory activities.

scientific article published on 24 January 2018

Is Mc1r an important regulator of non-pigmentary responses to UV radiation?

scientific article published on December 2013

Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?

scientific article

John Martin Wood (1938-2008)--pioneering biochemist, educator and communicator.

scientific article

KU812 basophils express urocortin, CRH-R, MC1R and steroidogenic enzymes and secrete progesterone

scientific article

Kinetics of vitamin D3 metabolism by cytochrome P450scc (CYP11A1) in phospholipid vesicles and cyclodextrin.

scientific article published on 20 May 2008

L-dopa binding sites in rodent melanoma cells

scientific article published in August 1992

L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions

scientific article published on 2 September 2011

L-tyrosine induces synthesis of melanogenesis related proteins

scientific article published on 01 January 1989

L-tyrosine induces tyrosinase expression via a posttranscriptional mechanism

scientific article published in July 1991

L-tyrosine stimulates induction of tyrosinase activity by MSH and reduces cooperative interactions between MSH receptors in hamster melanoma cells

scientific article published on 01 October 1989

L-tyrosine, L-dopa, and tyrosinase as positive regulators of the subcellular apparatus of melanogenesis in Bomirski Ab amelanotic melanoma cells

scientific article published on 01 March 1989

Lumisterol is metabolized by CYP11A1: discovery of a new pathway

scientific article

MSH binding in Bomirski amelanotic hamster melanoma cells is stimulated by L-tyrosine

scientific article published on 01 December 1987

Malignant melanoma 2003: predisposition, diagnosis, prognosis, and staging

scientific article published in December 2003

Mast cell involvement in murine hair growth.

scientific article published in May 1994

Melanin content in melanoma metastases affects the outcome of radiotherapy

scientific article published on 20 February 2016

Melanin pigmentation in mammalian skin and its hormonal regulation

scientific article

Melanocyte receptors: clinical implications and therapeutic relevance.

scientific article published on October 2007

Melanocytes as "sensory" and regulatory cells in the epidermis

scientific article

Melanocytic matricoma: a report of two cases of a new entity.

scientific article published on August 1999

Melanogenesis Is Directly Affected by Metabolites of Melatonin in Human Melanoma Cells

scientific article published on 6 October 2023

Melanogenesis affects overall and disease-free survival in patients with stage III and IV melanoma

scientific article published on 19 June 2013

Melanogenesis is coupled to murine anagen: toward new concepts for the role of melanocytes and the regulation of melanogenesis in hair growth

scientific article published on July 1993

Melanoma resistance: a bright future for academicians and a challenge for patient advocates

scientific article published on April 2014

Melanoma update: diagnostic and prognostic factors that can effectively shape and personalize management.

scientific article published on June 2011

Melanotropic activity of gamma MSH peptides in melanoma cells

scientific article published on January 1992

Melatonin and Its Metabolites Ameliorate UVR-Induced Mitochondrial Oxidative Stress in Human MNT-1 Melanoma Cells

scientific article published on 28 November 2018

Melatonin and its derivatives counteract the ultraviolet B radiation-induced damage in human and porcine skin ex vivo

scientific article published on 21 May 2018

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.

scientific article

Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.

scientific article

Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways

scientific article

Melatonin and the hair follicle

scientific article published on January 2008

Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

scientific article published on 17 July 2008

Melatonin exerts oncostatic capacity and decreases melanogenesis in human MNT-1 melanoma cells

scientific article published on 07 October 2019

Melatonin in the skin: synthesis, metabolism and functions

scientific article published on 26 December 2007

Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis

scientific article published in January 2006

Melatonin inhibits proliferation and melanogenesis in rodent melanoma cells

scientific article published on 01 June 1993

Melatonin maintains mitochondrial membrane potential and attenuates activation of initiator (casp-9) and effector caspases (casp-3/casp-7) and PARP in UVR-exposed HaCaT keratinocytes

scientific article published on 13 December 2007

Melatonin membrane receptors in peripheral tissues: distribution and functions

scientific article published on 8 January 2012

Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy

scientific article published on 29 April 2024

Melatonin: A Potential Regulator of DNA Methylation

scientific article published on 25 May 2023

Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3.

scientific article published on 21 October 2008

Metabolism of 20-hydroxyvitamin D3 and 20,23-dihydroxyvitamin D3 by rat and human CYP24A1

scientific article

Metabolism of 20-hydroxyvitamin D3 by mouse liver microsomes

scientific article

Metabolism of cholesterol, vitamin D3 and 20-hydroxyvitamin D3 incorporated into phospholipid vesicles by human CYP27A1

scientific article published on 24 December 2011

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.

scientific article published on 25 April 2013

Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes

scientific article published on 19 August 2008

Metabolism of melatonin in the skin: Why is it important?

scientific article published on 13 September 2016

Metabolism of progesterone to DOC, corticosterone and 18OHDOC in cultured human melanoma cells

scientific article published on 01 July 1999

Metabolism of vitamin d2 to 17,20,24-trihydroxyvitamin d2 by cytochrome p450scc (CYP11A1).

scientific article published on 30 December 2008

Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis.

scientific article

Microassay of phosphate provides a general method for measuring the activity of phosphatases using physiological, nonchromogenic substrates such as lysophosphatidic acid

scientific article published in November 2001

Modulation of the human hair follicle pigmentary unit by corticotropin-releasing hormone and urocortin peptides

scientific article

Molecular and functional characterization of novel CRFR1 isoforms from the skin

scientific article

Molecular cloning and initial characterization of African green monkey (Cercopithecus aethiops) corticotropin releasing factor receptor type 1 (CRF1) from COS-7 cells.

scientific article published on 10 November 2006

Molecular diagnostics in melanoma.

scientific article

Molecular mechanism of tyrosinase regulation by L-dopa in hamster melanoma cells

scientific article published on 01 January 1991

Molecular pathology of soft tissue and bone tumors. A review

scientific article

Murine skin as a target for melatonin bioregulation

scientific article published on 01 February 1994

N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.

scientific article

Neuro-immune-endocrine functions of the skin: an overview

scientific article published on January 2013

Neuroendocrine activity of the melanocyte

scientific article published on 23 June 2009

Neuroendocrinology of the skin: An overview and selective analysis

scientific article

Neuroimmunology of stress: skin takes center stage

scientific article

New techniques in dermatopathology that help to diagnose and prognosticate melanoma.

scientific article published on January 2009

New vitamin D analogs as potential therapeutics in melanoma

scientific article published on May 1, 2012

Nicotinic receptor signaling in nonexcitable epithelial cells: paradigm shifting from ion current to kinase cascade. Focus on "Upregulation of nuclear factor-kappaB expression by SLURP-1 is mediated by alpha7-nicotinic acetylcholine receptor and inv

scientific article published on August 25, 2010

Nme1 and Nme2 genes exert metastasis-suppressor activities in a genetically engineered mouse model of UV-induced melanoma

scientific article published on 07 October 2020

Noncalcemic 20-hydroxyvitamin D3 inhibits human melanoma growth in in vitro and in vivo models

scientific article published on 26 December 2016

Novel activities of CYP11A1 and their potential physiological significance.

scientific article published on 13 November 2014

Novel non-calcemic secosteroids that are produced by human epidermal keratinocytes protect against solar radiation.

scientific article

Novel vitamin D photoproducts and their precursors in the skin.

scientific article published on January 2013

Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling

scientific article

On the potential role of proopiomelanocortin in skin physiology and pathology

scientific article published on May 1993

On the role of environmental humidity on cortisol production by epidermal keratinocytes

scientific article published on January 2014

On the role of skin in the regulation of local and systemic steroidogenic activities.

scientific article

On the role of the corticotropin-releasing hormone signalling system in the aetiology of inflammatory skin disorders

scientific article published in February 2009

On the role of the endogenous opioid system in regulating epidermal homeostasis

scientific article published on February 2015

Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines.

scientific article published on September 2006

POMC gene expression in mouse and hamster melanoma cells

scientific article published on October 1991

Pathogenesis of psoriasis in the "omic" era. Part II. Genetic, genomic and epigenetic changes in psoriasis

scientific article published on 01 June 2020

Pathogenesis of psoriasis in the "omic" era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis

scientific article published on 01 August 2020

Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc

scientific article

Pharmacological disruption of hair follicle pigmentation by cyclophosphamide as a model for studying the melanocyte response to and recovery from cytotoxic drug damage in situ

scientific article published in June 1996

Possible mechanisms of hypopigmentation in lichen sclerosus.

scientific article

Pregnancy-driven cardiovascular maternal miR-29 plasticity in obesity.

scientific article published on 15 September 2016

Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background

scientific article

Pro-opiomelanocortin expression and potential function of pro-opiomelanocortin products during induced hair growth in mice

scientific article published on 01 December 1991

Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B

scientific article published on 01 August 1996

Production of 22-hydroxy metabolites of vitamin d3 by cytochrome p450scc (CYP11A1) and analysis of their biological activities on skin cells

scientific article

Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

scientific article

Proopiomelanocortin (POMC), the ACTH/melanocortin precursor, is secreted by human epidermal keratinocytes and melanocytes and stimulates melanogenesis.

scientific article

Proopiomelanocortin expression in the skin during induced hair growth in mice

scientific article published on 01 January 1992

Proopiomelanocortin signaling system is operating in mast cells

scientific article

Proopiomelanocortin, corticotropin releasing hormone and corticotropin releasing hormone receptor genes are expressed in human skin

scientific article

Purified mouse CYP27B1 can hydroxylate 20,23-dihydroxyvitamin D3, producing 1alpha,20,23-trihydroxyvitamin D3, which has altered biological activity

scientific article

Putative role of HIF transcriptional activity in melanocytes and melanoma biology

scientific article published on April 2013

RORα and ROR γ are expressed in human skin and serve as receptors for endogenously produced noncalcemic 20-hydroxy- and 20,23-dihydroxyvitamin D.

scientific article

RORα and RORγ expression inversely correlates with human melanoma progression.

scientific article published on 11 August 2016

RORα is not a receptor for melatonin (response to DOI 10.1002/bies.201600018).

scientific article published on 14 October 2016

Rapid melanization of bomirski amelanotic melanoma cells in cell culture

scientific article published on 01 February 1983

Rat CYP24A1 acts on 20-hydroxyvitamin D(3) producing hydroxylated products with increased biological activity

scientific article published on 5 October 2012

Regulated proenkephalin expression in human skin and cultured skin cells

scientific article

Regulation of retinoid mediated cholesterol efflux involves liver X receptor activation in mouse macrophages.

scientific article

Reply to Jakovac and to Rocha et al.: Can vitamin D prevent or manage COVID-19 illness?

scientific article published on 01 August 2020

Role of TRPM in melanocytes and melanoma.

scientific article

Role of the steroidogenic acute regulatory protein in health and disease

scientific article

Scalp nodule on a middle-aged woman

scientific article published on 01 October 2011

Serotonin metabolism in rat skin: characterization by liquid chromatography-mass spectrometry.

scientific article published in January 2004

Serotoninergic and melatoninergic systems are fully expressed in human skin

scientific article

Serotoninergic system in hamster skin

scientific article

Serum Vitamin D Concentrations in Baboons (Papio spp.) during Pregnancy and Obesity

scientific article published on January 2016

Skin as an endocrine organ: implications for its function

scientific article published on June 2008

Skin histoculture assay for studying the hair cycle

scientific article published on 01 November 1992

Skin under the sun: when melanin pigment meets vitamin D.

scientific article published in January 2015

Some properties of Bomirski Ab amelanotic melanoma cells, which underwent spontaneous melanization in primary cell culture. Growth kinetics, cell morphology, melanin content and tumorigenicity.

scientific article

Splenic eumelanin differs from hair eumelanin in C57BL/6 mice.

scientific article published on 25 June 2005

Steroidogenesis in the human skin: 21-hydroxylation in cultured keratinocytes

scientific article

Steroidogenesis in the skin: implications for local immune functions

scientific article

Stress-linked cortisol concentrations in hair: what we know and what we need to know.

scientific article

Sun-derived infrared A and ultraviolet B radiation: allies or enemies in melanomagenesis?

scientific article published on 17 June 2016

Synergistic activation of steroidogenic acute regulatory protein expression and steroid biosynthesis by retinoids: involvement of cAMP/PKA signaling

scientific article

Synthesis and Biological Evaluation of Vitamin D3 Metabolite 20S,23S-Dihydroxyvitamin D3 and Its 23R Epimer.

scientific article published on 12 April 2016

Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives

scientific article published on 04 September 2008

Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity.

scientific article published on 9 November 2010

TRPM1 (melastatin) expression is an independent predictor of overall survival in clinical AJCC stage I and II melanoma patients

scientific article

Targeting ALDH1A1 to treat pigmentary disorders.

scientific article published on May 2013

Targeting melanocortin receptor type 1 with small peptides

scientific article published on 01 July 2019

The correlation of TRPM1 (Melastatin) mRNA expression with microphthalmia-associated transcription factor (MITF) and other melanogenesis-related proteins in normal and pathological skin, hair follicles and melanocytic nevi.

scientific article

The cutaneous serotoninergic/melatoninergic system: securing a place under the sun.

scientific article

The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism.

scientific article published on August 2005

The expression of proopiomelanocortin (POMC) and of corticotropin releasing hormone receptor (CRH-R) genes in mouse skin

scientific article published on 01 March 1996

The fate of hair follicle melanocytes during the hair growth cycle

scientific article

The melatonin-producing system is fully functional in retinal pigment epithelium (ARPE-19).

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The natural history of a family of transplantable melanomas in hamsters.

scientific article published on June 1988

The potential role of vitamin D in the progression of benign and malignant melanocytic neoplasms

scientific article published on October 2010

The proopiomelanocortin system in cutaneous neuroimmunomodulation. An introductory overview

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The role of CYP11A1 in the production of vitamin D metabolites and their role in the regulation of epidermal functions.

scientific article published on 28 October 2013

The role of melanogenesis in regulation of melanoma behavior: melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways.

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The serum vitamin D metabolome: What we know and what is still to discover

scientific article published on 08 September 2018

The skin POMC system (SPS). Leads and lessons from the hair follicle

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The skin as a mirror of the soul: exploring the possible roles of serotonin.

scientific article published on 31 December 2007

The skin produces urocortin

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Thyroid hormones directly alter human hair follicle functions: anagen prolongation and stimulation of both hair matrix keratinocyte proliferation and hair pigmentation

scientific article published on 26 August 2008

Total synthesis of biologically active 20S-hydroxyvitamin D3.

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Towards defining receptors for L-tyrosine and L-dopa

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Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy-From Animal Models to Clinical Trials.

scientific article published in April 2018

Transplantable melanomas in gerbils (Meriones unguiculatus). II: melanogenesis.

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Tryptophan hydroxylase expression in human skin cells

scientific article published on October 2003

Tyrosinase activity in primary cell culture of amelanotic melanoma cells

scientific article published on 01 November 1983

UVB Activates Hypothalamic-Pituitary-Adrenal Axis in C57BL/6 Mice.

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UVB stimulates production of enkephalins and other neuropeptides by skin-resident cells

scientific article published on 01 January 2021

Ultraviolet B and Melanocyte-Stimulating Hormone (MSH) Stimulate mRNA Production for ∝MSH Receptors and Proopiomelanocortin-Derived Peptides in Mouse Melanoma Cells and Transformed Keratinocytes

scientific article published on November 1, 1995

Ultraviolet B stimulates production of corticotropin releasing factor (CRF) by human melanocytes

scientific article published on 01 December 1996

Ultraviolet B stimulates proopiomelanocortin signalling in the arcuate nucleus of the hypothalamus in mice.

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Ultraviolet Radiation-Induced Mitochondrial Disturbances Are Attenuated by Metabolites of Melatonin in Human Epidermal Keratinocytes

scientific article published on 20 July 2023

Ultraviolet radiation (UVR) activates central neuro-endocrine-immune system.

scientific article published on 20 February 2015

Up-regulation of steroid biosynthesis by retinoid signaling: Implications for aging.

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Viewpoint 1

scientific article published on 01 February 2008

Vitamin D Signaling in Psoriasis: Pathogenesis and Therapy

scientific article published on 2 August 2022

Vitamin D analogs 17,20S(OH)2pD and 17,20R(OH)2pD are noncalcemic and exhibit antifibrotic activity.

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Vitamin D derivatives enhance cytotoxic effects of H2O2 or cisplatin on human keratinocytes

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Vitamin D receptors (VDR), hydroxylases CYP27B1 and CYP24A1 and retinoid-related orphan receptors (ROR) level in human uveal tract and ocular melanoma with different melanization levels

scientific article published on 24 June 2019

Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management.

scientific article published on 20 February 2017

Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?

Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?

scholarly article by Lübeck Ralf Paus et al published February 2008 in Experimental Dermatology

Volar melanotic macules in a gardener: a case report and review of the literature

scientific article published on December 2008

What are melanocytes really doing all day long...?

scientific article published on 30 July 2009

What are subcutaneous adipocytes really good for?

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When the circadian clock meets the melanin pigmentary system

scientific article published on April 2015