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List of works by Thomas S Weiss

A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease

scientific article

A systems biology approach to dynamic modeling and inter-subject variability of statin pharmacokinetics in human hepatocytes

scientific article

Adiponectin and its receptors in rodent models of fatty liver disease and liver cirrhosis

scientific article

Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes.

scientific article published on 7 April 2011

Adiponectin isoforms differentially affect gene expression and the lipidome of primary human hepatocytes

scientific article

Adiponectin reduces connective tissue growth factor in human hepatocytes which is already induced in non-fibrotic non-alcoholic steatohepatitis

scientific article

Adiponectin upregulates hepatocyte CMKLR1 which is reduced in human fatty liver.

scientific article published on 18 November 2011

Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-kappaB, and STAT3 signaling pathways

scientific article

Aldehyde oxidase 1 is highly abundant in hepatic steatosis and is downregulated by adiponectin and fenofibric acid in hepatocytes in vitro.

scientific article

Annexin A6 protein is downregulated in human hepatocellular carcinoma.

scientific article

Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver

scientific article published on 17 February 2020

Apoptosis on hepatoma cells but not on primary hepatocytes by histone deacetylase inhibitors valproate and ITF2357.

scientific article published on February 2005

Attenuated and protease-profile modified sendai virus vectors as a new tool for virotherapy of solid tumors

scientific article

Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways

scientific article published on 6 September 2017

Augmented liver inflammation in a microsomal prostaglandin E synthase 1 (mPGES-1)-deficient diet-induced mouse NASH model

scientific article published in Scientific Reports

Augmenter of Liver Regeneration Reduces Ischemia Reperfusion Injury by Less Chemokine Expression, Gr-1 Infiltration and Oxidative Stress

scientific article published on 12 November 2019

Augmenter of liver regeneration (ALR) exhibits a dual signaling impact on hepatic acute-phase response

scientific article published on 12 May 2017

Augmenter of liver regeneration: Essential for growth and beyond

scientific article published on 16 December 2018

Bile acid-induced apoptosis and bile acid synthesis are reduced by over-expression of Augmenter of Liver Regeneration (ALR) in a STAT3-dependent mechanism

scientific article published on 28 November 2018

Bile acids down-regulate the expression of Augmenter of Liver Regeneration (ALR) via SHP/HNF4α1 and independent of Egr-1

scientific article published on 20 September 2018

Bone morphogenetic protein 4 is induced in hepatocellular carcinoma by hypoxia and promotes tumour progression

scientific article

Calnuc, an EF-hand Ca(2+) binding protein, specifically interacts with the C-terminal alpha5-helix of G(alpha)i3.

scientific article

Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B.

scientific article

Cell therapeutic options in liver diseases: cell types, medical devices and regulatory issues.

scientific article published on 3 April 2011

Cellular damage to human hepatocytes through repeated application of 5-aminolevulinic acid

scientific article published in April 2003

Ceramide and polyunsaturated phospholipids are strongly reduced in human hepatocellular carcinoma

scientific article published on 26 August 2016

Characterization of rat and human Kupffer cells after cryopreservation.

scientific article published on 8 January 2007

Charitable State-Controlled Foundation Human Tissue and Cell Research: Ethic and Legal Aspects in the Supply of Surgically Removed Human Tissue For Research in the Academic and Commercial Sector in Germany

scientific article

Chemerin Is Induced in Non-Alcoholic Fatty Liver Disease and Hepatitis B-Related Hepatocellular Carcinoma

scientific article published on 13 October 2020

Chemerin is highly expressed in hepatocytes and is induced in non-alcoholic steatohepatitis liver ⬇️

scientific article published on July 29, 2013

Chemokine (CC-motif) receptor-like 2 mRNA is expressed in hepatic stellate cells and is positively associated with characteristics of non-alcoholic steatohepatitis in mice and men.

scientific article published on 6 June 2017

Chemokine-Like Receptor 1 mRNA Weakly Correlates with Non-Alcoholic Steatohepatitis Score in Male but Not Female Individuals

scientific article published on 18 August 2016

Collagen sandwich culture affects intracellular polyamine levels of human hepatocytes

scientific article published in October 2002

Combined logical and data-driven models for linking signalling pathways to cellular response.

scientific article

Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling

scientific article

Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists

scientific article published on 26 August 2015

Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data

scientific article

Corrigendum to “Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in-vitro” [Exp. Mol. Pathol. 91-3 (2011) 733–739]

scholarly article published in Experimental and Molecular Pathology

Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.

scientific article

Diagnostic Value of Systemic Cholesteryl Ester/Free Cholesterol Ratio in Hepatocellular Carcinoma.

scientific article published in July 2017

Direct and natural killer cell-mediated antitumor effects of low-dose bortezomib in hepatocellular carcinoma

scientific article

Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα).

scientific article published on 7 January 2013

Does ALR deficiency pave the way for NASH progression?

scientific article published on 29 March 2020

Does hepatic steatosis affect drug metabolizing enzymes in the liver?

scientific article published on January 2011

Down-regulation of methylthioadenosine phosphorylase (MTAP) induces progression of hepatocellular carcinoma via accumulation of 5'-deoxy-5'-methylthioadenosine (MTA).

scientific article

Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation

scientific article published on 23 November 2010

Effect of heat-shock protein-90 (HSP90) inhibition on human hepatocytes and on liver regeneration in experimental models

scientific article published on 16 December 2009

Effects of atorvastatin metabolites on induction of drug‐metabolizing enzymes and membrane transporters through human pregnane X receptor ⬇️

scientific article published on March 1, 2012

Elevated adiponectin serum levels in patients with chronic alcohol abuse rapidly decline during alcohol withdrawal

scientific article published on 2 December 2008

Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma.

scientific article published on May 2007

Expression of augmenter of liver regeneration (ALR) in human liver cirrhosis and carcinoma.

scientific article

Extracellular factors and immunosuppressive drugs influencing insulin secretion of murine islets

scientific article published on 01 November 2012

Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells.

scientific article

GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis

scientific article published on 12 March 2009

Galpha i3 binding to calnuc on Golgi membranes in living cells monitored by fluorescence resonance energy transfer of green fluorescent protein fusion proteins

scientific article

Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue

scientific article published on 23 June 2016

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.

scientific article published on 25 May 2015

HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

scientific article published on March 2006

HIF-1beta determines ABCA1 expression under hypoxia in human macrophages

scientific article published on 12 October 2009

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.

scientific article published on 17 May 2016

Hepatic chemerin mRNA expression is reduced in human nonalcoholic steatohepatitis

scientific article published on 31 October 2016

Hepatic progenitor cells from adult human livers for cell transplantation.

scientific article

Hepatic scavenger receptor BI is associated with type 2 diabetes but unrelated to human and murine non-alcoholic fatty liver disease

scientific article published on 30 September 2015

Hepatitis B virus induces expression of antioxidant response element-regulated genes by activation of Nrf2.

scientific article published on 18 October 2010

Hepatitis C virus impairs the induction of cytoprotective Nrf2 target genes by delocalization of small Maf proteins

scientific article published on 7 January 2011

Hepatocyte Polarization Is Essential for the Productive Entry of the Hepatitis B Virus ⬇️

scientific article published on December 16, 2011

High molecular weight adiponectin reduces apolipoprotein B and E release in human hepatocytes

scientific article published on 20 November 2006

High-Resolution Reversed-Phase High-Performance Liquid Chromatography Analysis of Polyamines and Their Monoacetyl Conjugates by Fluorescence Detection after Derivatization withN-Hydroxysuccinimidyl 6-Quinolinyl Carbamate

article

Human parenchymal and non-parenchymal liver cell isolation, culture and characterization

scientific article published on 10 October 2013

IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro

scientific article published on 4 January 2007

Identification of α-taxilin as an essential factor for the life cycle of hepatitis B virus.

scientific article

Increased Expression of RUNX1 in Liver Correlates with NASH Activity Score in Patients with Non-Alcoholic Steatohepatitis (NASH)

scientific article published on 18 October 2019

Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry.

scientific article published on 4 March 2015

Insulin decreases inflammatory signal transcription factor expression in primary human liver cells after LPS challenge

scientific article published on January 2008

Intracellular polyamine levels of intestinal epithelial cells in inflammatory bowel disease

scientific article published in September 2004

Kaempferol, a new nutrition-derived pan-inhibitor of human histone deacetylases.

scientific article

Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor

scientific article published on 13 April 2017

Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells

scientific article

Lipid-induced up-regulation of human acyl-CoA synthetase 5 promotes hepatocellular apoptosis.

scientific article published on 12 May 2010

Liver Lipids of Patients with Hepatitis B and C and Associated Hepatocellular Carcinoma ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Liver regeneration associated protein (ALR) exhibits antimetastatic potential in hepatocellular carcinoma.

scientific article

MMP-9 activity is increased by adiponectin in primary human hepatocytes but even negatively correlates with serum adiponectin in a rodent model of non-alcoholic steatohepatitis

scientific article published on 21 July 2011

Manganese superoxide dismutase is reduced in the liver of male but not female humans and rodents with non-alcoholic fatty liver disease

scientific article published on 22 October 2013

Metformin reduces cellular lysophosphatidylcholine and thereby may lower apolipoprotein B secretion in primary human hepatocytes

scientific article published on 3 May 2008

Myristoylated PreS1-domain of the hepatitis B virus L-protein mediates specific binding to differentiated hepatocytes

scientific article

Nicotinic acid inhibits hepatic APOA gene expression: studies in humans and in transgenic mice

scientific article

Novel inhibitors of cyclin-dependent kinases combat hepatocellular carcinoma without inducing chemoresistance.

scientific article published on 12 August 2013

Nrf2 activates augmenter of liver regeneration (ALR) via antioxidant response element and links oxidative stress to liver regeneration.

scientific article published on 28 August 2013

Pentraxin-3 is not related to disease severity in cirrhosis and hepatocellular carcinoma patients

scientific article published on 20 February 2020

Perilipin 5 and Lipocalin 2 Expression in Hepatocellular Carcinoma

scientific article published on 19 March 2019

Photo-oxidative killing of human colonic cancer cells using indocyanine green and infrared light

scientific article

Polyamine levels of human colorectal adenocarcinomas are correlated with tumor stage and grade

scientific article published on 20 April 2002

Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes

scientific article

Promoter-hypermethylation is causing functional relevant downregulation of methylthioadenosine phosphorylase (MTAP) expression in hepatocellular carcinoma

scientific article

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

scientific article published on 23 August 2013

Reduced serum chemerin in patients with more severe liver cirrhosis

scientific article published on 13 January 2015

Regulation of adiponectin receptor 1 in human hepatocytes by agonists of nuclear receptors

scientific article

Regulation of polyamine synthesis in human hepatocytes by hepatotrophic factor augmenter of liver regeneration

scientific article published on 24 April 2006

Repression of cytochrome P450 activity in human hepatocytes in vitro by a novel hepatotrophic factor, augmenter of liver regeneration

scientific article published on 7 October 2005

Resveratrol as a pan-HDAC inhibitor alters the acetylation status of histone [corrected] proteins in human-derived hepatoblastoma cells

scientific article (publication date: 2013)

Selective protection of human liver tissue in TNF-targeting of cancers of the liver by transient depletion of adenosine triphosphate

scientific article

Serum Adiponectin Levels Do Not Distinguish Primary from Metastatic Liver Tumors

scientific article published on 01 January 2020

Serum Chemerin Does Not Differentiate Colorectal Liver Metastases from Hepatocellular Carcinoma

scientific article published on 12 August 2019

Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma

scientific article

Soluble CD163 is not increased in visceral fat and steatotic liver and is even suppressed by free fatty acids in vitro

scientific article published on 3 August 2011

Systemic and hepatic vein galectin-3 are increased in patients with alcoholic liver cirrhosis and negatively correlate with liver function

scientific article published on 28 June 2011

TGF-β2 silencing to target biliary-derived liver diseases

scientific article published on 28 January 2020

THE ANTINEOPLASTIC DRUG PACLITAXEL HAS IMMUNOSUPPRESSIVE PROPERTIES THAT CAN EFFECTIVELY PROMOTE ALLOGRAFT SURVIVAL IN A RAT HEART TRANSPLANT MODEL1

scientific article published on 01 January 2002

TIP47 plays a crucial role in the life cycle of hepatitis C virus

scientific article published on 24 January 2013

The adaptor protein alpha-syntrophin is reduced in human non-alcoholic steatohepatitis but is unchanged in hepatocellular carcinoma

scientific article

The establishment of a network of European human research tissue banks

article

The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

scientific article published on 30 June 2015

Thy-1 (CD90)-Positive Hepatic Progenitor Cells, Hepatoctyes, and Non-parenchymal Liver Cells Isolated from Human Livers.

scientific article published in January 2017

Toxicogenomics directory of chemically exposed human hepatocytes

scientific article

Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes

scientific article published on 27 April 2016

Tubulin alpha 8 is expressed in hepatic stellate cells and is induced in transformed hepatocytes

scientific article published on 7 January 2017

Xanthohumol, a chalcon derived from hops, inhibits hepatic inflammation and fibrosis

scientific article published in July 2010

β-Defensin 1 Is Prominent in the Liver and Induced During Cholestasis by Bilirubin and Bile Acids Farnesoid X Receptor and Constitutive Androstane Receptor ⬇️

scientific article published on 27 July 2018

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