List of works - Michael Grusch

Vaults and the major vault protein: novel roles in signal pathway regulation and immunity

scientific article

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

scientific article

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.

scientific article published on 11 February 2011

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

scientific article

FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities

scientific article published on 24 March 2008

Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B.

scientific article

Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition

scientific article

Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration.

scientific article

The activin axis in liver biology and disease.

scientific article published on 25 September 2006

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.

scientific article published on 07 March 2011

FGF18 in colorectal tumour cells: autocrine and paracrine effects

scientific article

Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells.

scientific article published on 20 February 2006

NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

scientific article

Deregulation of the activin/follistatin system in hepatocarcinogenesis

scientific article

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

scientific article published on 3 November 2010

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

scientific article published on May 2015

Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer

scientific article

Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis

scientific article

Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis

scientific article

Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma

scientific article published on 16 January 2014

Apelin promotes lymphangiogenesis and lymph node metastasis.

scientific article

Expression of activins C and E induces apoptosis in human and rat hepatoma cells.

scientific article published on 29 August 2003

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy

scientific article

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

scientific article published on 3 November 2014

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver

scientific article published on 25 September 2007

DNA Methylation as a Noninvasive Epigenetic Biomarker for the Detection of Cancer

scientific article published on 5 September 2017

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis

scientific article

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis

scientific article

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro

scientific article

Cdc25A phosphatase suppresses apoptosis induced by serum deprivation

scientific article

Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.

scientific article published on October 2014

Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells

scientific article published on 01 October 2006

Pretreatment serum C-reactive protein levels predict benefit from multimodality treatment including radical surgery in malignant pleural mesothelioma: a retrospective multicenter analysis

scientific article published in August 2012

Ki67 index is an independent prognostic factor in epithelioid but not in non-epithelioid malignant pleural mesothelioma: a multicenter study

scientific article published on 29 January 2015

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.

scientific article published on 26 May 2015

Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis

scientific article published on 4 August 2005

HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis.

scientific article

Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

scientific article

Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion

scientific article published on October 23, 2012

Activins and follistatins: Emerging roles in liver physiology and cancer

scientific article

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

scientific article published on 17 March 2013

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

scientific article

Novel resveratrol derivatives induce apoptosis and cause cell cycle arrest in prostate cancer cell lines.

scientific article

NORE1B is a putative tumor suppressor in hepatocarcinogenesis and may act via RASSF1A.

scientific article

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells

scientific article published on 17 January 2012

Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465.

scientific article published in December 2010

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

scientific article

Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells

scientific article published on 25 October 2008

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

scientific article

Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy

scientific article

List of works by Michael Grusch

Vaults and the major vault protein: novel roles in signal pathway regulation and immunity

Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.

Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis.

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities

Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B.

Fibroblast growth factor receptors as therapeutic targets in human melanoma: synergism with BRAF inhibition

Fibroblast growth factor receptor 3-IIIc mediates colorectal cancer growth and migration.

The activin axis in liver biology and disease.

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.

FGF18 in colorectal tumour cells: autocrine and paracrine effects

Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells.

NF-κB mediates the 12(S)-HETE-induced endothelial to mesenchymal transition of lymphendothelial cells during the intravasation of breast carcinoma cells

Deregulation of the activin/follistatin system in hepatocarcinogenesis

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma.

Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer

Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis

Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis

Circulating fibrinogen is a prognostic and predictive biomarker in malignant pleural mesothelioma

Apelin promotes lymphangiogenesis and lymph node metastasis.

Expression of activins C and E induces apoptosis in human and rat hepatoma cells.

Subtype-specific KRAS mutations in advanced lung adenocarcinoma: a retrospective study of patients treated with platinum-based chemotherapy

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver

DNA Methylation as a Noninvasive Epigenetic Biomarker for the Detection of Cancer

Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis

Consequences of IMP dehydrogenase inhibition, and its relationship to cancer and apoptosis

Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro

Cdc25A phosphatase suppresses apoptosis induced by serum deprivation

Fibroblast growth factor receptor inhibition is active against mesothelioma and synergizes with radio- and chemotherapy.

Cytotoxic and biochemical effects of 3,3′,4,4′,5,5′-hexahydroxystilbene, a novel resveratrol analog in HL-60 human promyelocytic leukemia cells

Pretreatment serum C-reactive protein levels predict benefit from multimodality treatment including radical surgery in malignant pleural mesothelioma: a retrospective multicenter analysis

Ki67 index is an independent prognostic factor in epithelioid but not in non-epithelioid malignant pleural mesothelioma: a multicenter study

Epigenetic down-regulation of integrin α7 increases migratory potential and confers poor prognosis in malignant pleural mesothelioma.

Non-parenchymal liver cells support the growth advantage in the first stages of hepatocarcinogenesis

HB-EGF is a paracrine growth stimulator for early tumor prestages in inflammation-associated hepatocarcinogenesis.

Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?

Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion

Activins and follistatins: Emerging roles in liver physiology and cancer

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

High circulating activin A level is associated with tumor progression and predicts poor prognosis in lung adenocarcinoma.

Novel resveratrol derivatives induce apoptosis and cause cell cycle arrest in prostate cancer cell lines.

NORE1B is a putative tumor suppressor in hepatocarcinogenesis and may act via RASSF1A.

The major vault protein mediates resistance to epidermal growth factor receptor inhibition in human hepatoma cells

Response of experimental malignant melanoma models to the pan-Aurora kinase inhibitor VE-465.

Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers

Digalloylresveratrol, a new phenolic acid derivative induces apoptosis and cell cycle arrest in human HT-29 colon cancer cells

Fibroblast growth factor receptor 4: a putative key driver for the aggressive phenotype of hepatocellular carcinoma.

Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy