List of works - Daniel J Jagger

A deafness-associated mutant human connexin 26 improves the epithelial barrier in vitro

scientific article

A novel hearing-loss-related mutation occurring in the GJB2 basal promoter.

scientific article

A potassium current in guinea-pig outer hair cells activated by ion channel blocker DCDPC.

scientific article

A technique for slicing the rat cochlea around the onset of hearing

scientific article published in December 2000

A-type potassium currents dominate repolarisation of neonatal rat primary auditory neurones in situ

scientific article published in January 2002

ATP-gated currents in rat primary auditory neurones in situ arise from a heteromultimetric P2X receptor subunit assembly

scientific article published in March 2002

Allosteric modulation of native cochlear P2X receptors: insights from comparison with recombinant P2X2 receptors

scientific article published in May 2003

Alström Syndrome protein ALMS1 localizes to basal bodies of cochlear hair cells and regulates cilium-dependent planar cell polarity

scientific article

Assessing PCP in the cochlea of mammalian ciliopathy models

scientific article

Auditory hair cell precursors immortalized from the mammalian inner ear.

scientific article published in September 1998

Calcium signalling mediated by the 9 acetylcholine receptor in a cochlear cell line from the immortomouse

scientific article

Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing

scientific article

Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea.

scientific article published in January 2006

Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea

scientific article

Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling

scientific article

Contractility in type III cochlear fibrocytes is dependent on non-muscle myosin II and intercellular gap junctional coupling

scientific article published on 5 April 2012

Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions

scientific article published on 10 September 2015

Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell replacement in the Cochlea

scientific article

Development of gap junctional intercellular communication within the lateral wall of the rat cochlea

scientific article published on 12 February 2011

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

scientific journal article

Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.

scientific article

Divergent membrane properties of mouse cochlear glial cells around hearing onset

scientific article published on 25 October 2020

Functional P2X<sub>7</sub> Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia

scientific article published in 2021

Gap junctional coupling is essential for epithelial repair in the avian cochlea

scientific article

Identification of Persistent and Resurgent Sodium Currents in Spiral Ganglion Neurons Cultured from the Mouse Cochlea

scientific article published on 14 November 2017

Ionic currents expressed in a cell line derived from the organ of Corti of the Immortomouse.

scientific article published on June 1999

Membrane properties of type II spiral ganglion neurones identified in a neonatal rat cochlear slice ⬇️

scientific article published on October 15, 2003

Neuromodulation in the spiral ganglion: shaping signals from the organ of corti to the CNS.

scientific article published on February 2006

Olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties

scientific article published on 04 December 2019

P2X receptor signaling inhibits BDNF-mediated spiral ganglion neuron development in the neonatal rat cochlea

scientific article

Patterns of expression of Bardet-Biedl syndrome proteins in the mammalian cochlea suggest noncentrosomal functions

scientific article

Phosphoinositide Modulation of Heteromeric Kv1 Channels Adjusts Output of Spiral Ganglion Neurons from Hearing Mice

scientific article

Positional analysis of guinea pig inner hair cell membrane conductances: implications for regulation of the membrane filter.

scientific article

Potential role of purinergic signalling in cochlear pathology

scientific article

Purinergic regulation of sound transduction and auditory neurotransmission.

scientific article published in January 2002

Quantitative analysis of the expression of the glutamate-aspartate transporter and identification of functional glutamate uptake reveal a role for cochlear fibrocytes in glutamate homeostasis.

scientific article

Reducing Current Spread by Use of a Novel Pulse Shape for Electrical Stimulation of the Auditory Nerve.

scientific article

Regulation of ionic currents by protein kinase A and intracellular calcium in outer hair cells isolated from the guinea-pig cochlea

scientific article

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss

scientific article

TRPC-like conductance mediates restoration of intracellular Ca2+ in cochlear outer hair cells in the guinea pig and rat

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway

scientific article

The Meckel-Gruber Syndrome protein TMEM67 (meckelin) regulates basal body planar polarization and non-canonical Wnt signalling via Wnt5a and ROR2.

scientific article

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway ⬇️

scientific article published on 7 April 2015

The Membrane Properties of Cochlear Root Cells are Consistent with Roles in Potassium Recirculation and Spatial Buffering

scientific article

The enigmatic root cell - emerging roles contributing to fluid homeostasis within the cochlear outer sulcus

scientific article

The fast activating potassium current, I(K,f), in guinea-pig inner hair cells is regulated by protein kinase A.

scientific article published on March 1999

The inner ear contains heteromeric channels composed of cx26 and cx30 and deafness-related mutations in cx26 have a dominant negative effect on cx30.

scientific article published in July 2003

The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention

scientific article published in 2022

List of works by Daniel J Jagger

A deafness-associated mutant human connexin 26 improves the epithelial barrier in vitro

A novel hearing-loss-related mutation occurring in the GJB2 basal promoter.

A potassium current in guinea-pig outer hair cells activated by ion channel blocker DCDPC.

A technique for slicing the rat cochlea around the onset of hearing

A-type potassium currents dominate repolarisation of neonatal rat primary auditory neurones in situ

ATP-gated currents in rat primary auditory neurones in situ arise from a heteromultimetric P2X receptor subunit assembly

Allosteric modulation of native cochlear P2X receptors: insights from comparison with recombinant P2X2 receptors

Alström Syndrome protein ALMS1 localizes to basal bodies of cochlear hair cells and regulates cilium-dependent planar cell polarity

Assessing PCP in the cochlea of mammalian ciliopathy models

Auditory hair cell precursors immortalized from the mammalian inner ear.

Calcium signalling mediated by the 9 acetylcholine receptor in a cochlear cell line from the immortomouse

Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing

Compartmentalized and signal-selective gap junctional coupling in the hearing cochlea.

Connexin30-mediated intercellular communication plays an essential role in epithelial repair in the cochlea

Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling

Contractility in type III cochlear fibrocytes is dependent on non-muscle myosin II and intercellular gap junctional coupling

Cx30 exhibits unique characteristics including a long half-life when assembled into gap junctions

Defining the cellular environment in the organ of Corti following extensive hair cell loss: a basis for future sensory cell replacement in the Cochlea

Development of gap junctional intercellular communication within the lateral wall of the rat cochlea

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear.

Divergent membrane properties of mouse cochlear glial cells around hearing onset

Functional P2X<sub>7</sub> Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia

Gap junctional coupling is essential for epithelial repair in the avian cochlea

Identification of Persistent and Resurgent Sodium Currents in Spiral Ganglion Neurons Cultured from the Mouse Cochlea

Ionic currents expressed in a cell line derived from the organ of Corti of the Immortomouse.

Membrane properties of type II spiral ganglion neurones identified in a neonatal rat cochlear slice ⬇️

Neuromodulation in the spiral ganglion: shaping signals from the organ of corti to the CNS.

Olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties

P2X receptor signaling inhibits BDNF-mediated spiral ganglion neuron development in the neonatal rat cochlea

Patterns of expression of Bardet-Biedl syndrome proteins in the mammalian cochlea suggest noncentrosomal functions

Phosphoinositide Modulation of Heteromeric Kv1 Channels Adjusts Output of Spiral Ganglion Neurons from Hearing Mice

Positional analysis of guinea pig inner hair cell membrane conductances: implications for regulation of the membrane filter.

Potential role of purinergic signalling in cochlear pathology

Purinergic regulation of sound transduction and auditory neurotransmission.

Quantitative analysis of the expression of the glutamate-aspartate transporter and identification of functional glutamate uptake reveal a role for cochlear fibrocytes in glutamate homeostasis.

Reducing Current Spread by Use of a Novel Pulse Shape for Electrical Stimulation of the Auditory Nerve.

Regulation of ionic currents by protein kinase A and intracellular calcium in outer hair cells isolated from the guinea-pig cochlea

Spinster homolog 2 (spns2) deficiency causes early onset progressive hearing loss

TRPC-like conductance mediates restoration of intracellular Ca2+ in cochlear outer hair cells in the guinea pig and rat

The Alström syndrome protein, ALMS1, interacts with α-actinin and components of the endosome recycling pathway

The Meckel-Gruber Syndrome protein TMEM67 (meckelin) regulates basal body planar polarization and non-canonical Wnt signalling via Wnt5a and ROR2.

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway ⬇️

The Membrane Properties of Cochlear Root Cells are Consistent with Roles in Potassium Recirculation and Spatial Buffering

The enigmatic root cell - emerging roles contributing to fluid homeostasis within the cochlear outer sulcus

The fast activating potassium current, I(K,f), in guinea-pig inner hair cells is regulated by protein kinase A.

The inner ear contains heteromeric channels composed of cx26 and cx30 and deafness-related mutations in cx26 have a dominant negative effect on cx30.

The timing of auditory sensory deficits in Norrie disease has implications for therapeutic intervention