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List of works by Alexei Gratchev

A Novel Monoclonal Antibody Against Alpha-Methylacyl-CoA Racemase Applicable for Paraffin-Embedded Tissues and Diagnostics of Prostate Cancer.

scientific article published on 16 February 2017

A TNF-regulated recombinatorial macrophage immune receptor implicated in granuloma formation in tuberculosis

scientific article

A modification of the JAM test is necessary for a correct determination of apoptosis induced by FasL+ adherent tumor cells.

scientific article published in August 1998

A novel mutation in the XPA gene results in two truncated protein variants and leads to a severe XP/neurological symptoms phenotype

scientific article

A second combinatorial immune receptor in monocytes/macrophages is based on the TCRγδ.

scientific article published on 26 November 2012

Activation of a TGF-beta-specific multistep gene expression program in mature macrophages requires glucocorticoid-mediated surface expression of TGF-beta receptor II

scientific article

Additional Her 2/neu gene copies in patients with Sézary syndrome

scientific article published on 21 November 2005

Alternative activation of antigen-presenting cells: concepts and clinical relevance

scientific article published on 01 March 2001

Alternative versus classical activation of macrophages.

scientific article

Alternatively activated antigen-presenting cells: molecular repertoire, immune regulation, and healing.

scientific article

Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein betaIG-H3.

scientific article published in April 2001

Alternatively activated macrophages regulate extracellular levels of the hormone placental lactogen via receptor-mediated uptake and transcytosis

scientific article

An unusual mutation in the XPG gene leads to an internal in-frame deletion and a XP/CS complex phenotype

scientific article published on 26 July 2014

Antagonistic regulation of macrophage phenotype by M-CSF and GM-CSF: implication in atherosclerosis

scientific article published on 27 November 2010

Characterization of three XPG-defective patients identifies three missense mutations that impair repair and transcription

scientific article published on 31 January 2013

Correct evaluation of reporter assays in different cell lines by direct determination of the introduced plasmid amount.

scientific article published in February 2000

Cutaneous leiomyosarcoma with myxoid alteration arising in a setting of multiple cutaneous smooth muscle neoplasms

scientific article published on 01 September 2006

De novo expression of the Muc2 gene in pancreas carcinoma cells is triggered by promoter demethylation

scientific article published on January 2002

Deficiency of liver sinusoidal scavenger receptors stabilin-1 and -2 in mice causes glomerulofibrotic nephropathy via impaired hepatic clearance of noxious blood factors.

scientific article published on February 2011

Development and Characterization of a Novel Monoclonal Antibody Against Chitinase-like Protein CHID1 Applicable for Immunohistochemistry on Formalin Fixed Paraffin-Embedded Sections

scientific article published on 18 January 2019

Differential expression of a gene signature for scavenger/lectin receptors by endothelial cells and macrophages in human lymph node sinuses, the primary sites of regional metastasis

scientific article published on 01 March 2006

Differential gene expression in colon carcinoma cells and tissues detected with a cDNA array

scientific article published on September 1999

Expression of Osteoarthritis Marker YKL-39 is Stimulated by Transforming Growth Factor Beta (TGF-beta) and IL-4 in Differentiating Macrophages

scientific article published on 14 February 2008

FasL is more frequently expressed in liver metastases of colorectal cancer than in matched primary carcinomas

scientific article published on March 1999

Functional and molecular genetic analyses of nine newly identified XPD-deficient patients reveal a novel mutation resulting in TTD as well as in XP/CS complex phenotypes

scientific article published on July 2013

Functional characterization of the epidermal cholinergic system in vitro

scientific article

Functional significance of non-neuronal acetylcholine in skin epithelia

scientific article published on 20 February 2007

Harnessing the multifunctionality in nature: a bioactive agent release system with self-antimicrobial and immunomodulatory properties

scientific article published on September 2015

Human Lung Microbiome on the Way to Cancer

scientific article published on 29 July 2019

Hyperglycemia induces mixed M1/M2 cytokine profile in primary human monocyte-derived macrophages.

scientific article published on 22 July 2016

IL-4 driven transcription factor FoxQ1 is expressed by monocytes in atopic dermatitis and stimulates monocyte migration.

scientific article published on 4 December 2017

Immunosuppressive Phenotype of Esophagus Tumors Stroma

scientific article published on 20 August 2020

Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy

scientific article

Interleukin-4 and dexamethasone counterregulate extracellular matrix remodelling and phagocytosis in type-2 macrophages.

scientific article published in January 2005

Lung Microbiome Differentially Impacts Survival of Patients with Non-Small Cell Lung Cancer Depending on Tumor Stroma Phenotype

scientific article published on 13 September 2020

MUC2 gene suppression in human colorectal carcinomas and their metastases: in vitro evidence of the modulatory role of DNA methylation

scientific article published on December 1, 1997

Macrophage Phenotype in Combination with Tumor Microbiome Composition Predicts RCC Patients’ Survival: A Pilot Study

scientific article published in 2022

Macrophages in immunopathology of atherosclerosis: a target for diagnostics and therapy.

scientific article published on January 2015

Macrophages of human first trimester decidua express markers associated to alternative activation

scientific article published in February 2004

Molecular and immunologic markers of kidney cancer-potential applications in predictive, preventive and personalized medicine

scientific article

Molecular genetic analysis of 16 XP-C patients from Germany: environmental factors predominately contribute to phenotype variations

scientific article published on 22 November 2012

Molecular genetics of Xeroderma pigmentosum variant.

scientific article published in October 2003

Monocytes as a diagnostic marker of cardiovascular diseases.

scientific article published on 13 January 2012

Mphi1 and Mphi2 can be re-polarized by Th2 or Th1 cytokines, respectively, and respond to exogenous danger signals

scientific article published on 21 July 2006

Novel biomarkers of hidden inflammation and implantation

scientific article published on 11 February 2014

Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway

scientific article

On the horizon: flexible immune recognition outside lymphocytes.

scientific article published on June 2012

Overexpression of c-myb in leukaemic and non-leukaemic variants of cutaneous T-cell lymphoma

scientific article published in January 2005

Perspectives for Monocyte/Macrophage-Based Diagnostics of Chronic Inflammation

scientific article

Perspectives of personalized immunomodulation in dentistry

scientific article published on 11 February 2014

Phenotypical and molecular profiling of the extraneuronal cholinergic system of the skin

scientific article

Phosphatidylinositide 3-kinase activity is required for stabilin-1-mediated endosomal transport of acLDL.

scientific article published in January 2005

Pro- and anti-inflammatory control of M-CSF-mediated macrophage differentiation

scientific article published on 15 June 2010

Prognostic significance of sPD-1/sPD-L1 in renal cancer depending on the phenotype of tumor and stromal cells

scientific article published in 2022

Regulation of mucin MUC2 gene expression during colon carcinogenesis.

scientific article

Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation

scientific article

Smoking-related DNA adducts as potential diagnostic markers of lung cancer: new perspectives

scientific article published on March 2015

Smurf2 regulates IL17RB by proteasomal degradation of its novel binding partner DAZAP2.

scientific article

Stabilin-1 and -2 constitute a novel family of fasciclin-like hyaluronan receptor homologues

scientific article

Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model.

scientific article published on 20 April 2016

Stabilin-1 mediates phosphatidylserine-dependent clearance of cell corpses in alternatively activated macrophages

scientific article

TGF-β signalling in tumour associated macrophages

scientific article published on February 2016

TGF-β1, but not bone morphogenetic proteins, activates Smad1/5 pathway in primary human macrophages and induces expression of proatherogenic genes.

scientific article published on 12 December 2014

The neutrophil recombinatorial TCR-like immune receptor is expressed across the entire human life span but repertoire diversity declines in old age.

scientific article published on 11 February 2012

The nucleotide excision repair of DNA in human cells and its association with xeroderma pigmentosum.

scientific article published on January 2008

The receptor for interleukin-17E is induced by Th2 cytokines in antigen-presenting cells

scientific article published on 01 September 2004

Tumor Associated Macrophages in Kidney Cancer

scientific article

[Cutaneous non-Langerhans' cell histiocytoses]

scientific article published on 01 June 2003

[Increased methylation of promotor region suppresses expression of MUC2 gene in colon carcinoma cells]

scientific article

[Interaction of native and modified low density lipoprotein with intimal cells in atherosclerotic lesion]

[beta-catenin overexpression in metastasized colorectal carcinoma--an important mechanism in progression of the disease?].

scientific article

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