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List of works by James P. Tam

A Facile Ligation Approach to Prepare Three-Helix Bundles of HIV Fusion-State Protein Mimetics

article

A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides

scientific article published on 11 March 2016

A novel PCR-based technology for rapid and non-sequencing authentication of Bombyx batryticatus using species-specific primers

scientific article published on 23 April 2018

A novel strategy for the discrimination of gelatinous Chinese medicines based on enzymatic digestion followed by nano-flow liquid chromatography in tandem with orbitrap mass spectrum detection

scientific article

A thioethylalkylamido (TEA) thioester surrogate in the synthesis of a cyclic peptide via a tandem acyl shift.

scientific article

A universal description for the experimental behavior of salt-(in)dependent oligocation-induced DNA condensation.

scientific article published on November 2009

Acid-Catalyzed Tandem Thiol Switch for Preparing Peptide Thioesters from Mercaptoethyl Esters

scientific article published on 26 April 2011

Alanine scan of endothelin: Importance of aromatic residues

scientific article published on 01 January 1994

Allotides: Proline-Rich Cystine Knot α-Amylase Inhibitors from Allamanda cathartica

scientific article published on 02 April 2015

An Orally Active Bradykinin B1 Receptor Antagonist Engineered as a Bifunctional Chimera of Sunflower Trypsin Inhibitor

scientific article

Antimicrobial Peptides from Plants

scientific article

Antimicrobial dendrimeric peptides

scientific article published in February 2002

Antiviral Cystine Knot α-Amylase Inhibitors from Alstonia scholaris.

scientific article

Astratides: Insulin-Modulating, Insecticidal, and Antifungal Cysteine-Rich Peptides from Astragalus membranaceus

scientific article published on 13 February 2019

Autoantibodies and immune complexes to oxidation-specific epitopes and progression of aortic stenosis: Results from the ASTRONOMER trial

scientific article published on 9 March 2017

Biochemical and functional characterization of Epstein-Barr virus-encoded BARF1 protein: interaction with human hTid1 protein facilitates its maturation and secretion

scientific article published on 6 March 2006

Biochemical and functional characterization of the membrane association and membrane permeabilizing activity of the severe acute respiratory syndrome coronavirus envelope protein

scientific article published on 28 February 2006

Biochemical evidence for the presence of mixed membrane topologies of the severe acute respiratory syndrome coronavirus envelope protein expressed in mammalian cells

article

Biomimetic synthesis of cyclic peptides using novel thioester surrogates

scientific article published in September 2013

Biophysical properties and supramolecular structure of self-assembled liposome/ε-peptide/DNA nanoparticles: correlation with gene delivery

scientific article published in December 2011

Bleogens: Cactus-Derived Anti-Candida Cysteine-Rich Peptides with Three Different Precursor Arrangements

scientific article published on 22 December 2017

Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis

scientific article (publication date: September 2014)

Butelase 1: A Versatile Ligase for Peptide and Protein Macrocyclization.

scientific article published on 3 December 2015

Butelase-Mediated Ligation as an Efficient Bioconjugation Method for the Synthesis of Peptide Dendrimers.

scientific article

Butelase-Mediated Macrocyclization of d-Amino-Acid-Containing Peptides

scientific article

Butelase-mediated cyclization and ligation of peptides and proteins.

scientific article published on 22 September 2016

Butelase-mediated synthesis of protein thioesters and its application for tandem chemoenzymatic ligation

scientific article published on 01 December 2015

Calcium binding and putative activity of the epidermal growth factor domain of blood coagulation Factor IX

article

Cell cycle arrest and apoptosis induced by the coronavirus infectious bronchitis virus in the absence of p53.

scientific article published on 9 May 2007

Chemically unambiguous peptide immunogen: Preparation, orientation and antigenicity of purified peptide conjugated to the multiple antigen peptide system

scientific article published on 01 June 1991

Commercial processed soy-based food product contains glycated and glycoxidated lunasin proteoforms

scientific article (publication date: 18 May 2016)

Convenient preparation of sagittatoside B, a rare bioactive secondary flavonol glycoside, by recyclable and integrated biphase enzymatic hydrolysis

scientific article published on 03 December 2018

Correction of errors in tandem mass spectrum extraction enhances phosphopeptide identification.

scientific article

Correction to Immobilized Peptide Asparaginyl Ligases Enhance Stability and Facilitate Macrocyclization and Site-Specific Ligation

scientific article published on 05 March 2020

Correlations of cationic charges with salt sensitivity and microbial specificity of cystine-stabilized beta -strand antimicrobial peptides

scientific article published on 23 October 2002

Cyclization of a G4-specific peptide enhances its stability and G-quadruplex binding affinity

scientific article published on 01 January 2020

Cysteine-Rich Peptide Family with Unusual Disulfide Connectivity from Jasminum sambac

scientific article published on 10 November 2015

Cysteine-Rich Peptide Fingerprinting as a General Method for Herbal Analysis to Differentiate Radix Astragali and Radix Hedysarum

scientific article published on 31 July 2019

Dementia-linked amyloidosis is associated with brain protein deamidation as revealed by proteomic profiling of human brain tissues

scientific article published on 19 February 2016

Design and biophysical characterization of novel polycationic epsilon-peptides for DNA compaction and delivery

scientific article published on 30 November 2007

Design of Gram-negative selective antimicrobial peptides

scientific article

Design of Salt-Insensitive Glycine-Rich Antimicrobial Peptides with Cyclic Tricystine Structures†

scientific article published on 01 June 2000

Dietary phytochemical PEITC restricts tumor development via modulation of epigenetic writers and erasers

scientific article published on 12 January 2017

Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family

scientific article

Discovery of Linear Cyclotides in Monocot Plant Panicum laxum of Poaceae Family Provides New Insights into Evolution and Distribution of Cyclotides in Plants

scientific article published on November 29, 2012

Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry

scientific article

Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides. Endogenous 5-HT(2C) receptors in choroid plexus epithelial cells

scientific article published in March 2000

Eco-efficient biphasic enzymatic hydrolysis for the green production of rare baohuoside I

scientific article published on 17 September 2019

Editorial: Ligation and splicing of peptides and proteins

scientific article published on 01 January 1999

Elucidating the structure of cyclotides by partial acid hydrolysis and LC-MS/MS analysis.

scientific article published in February 2009

Engineered salt-insensitive alpha-defensins with end-to-end circularized structures

scientific article

Engineering a Catalytically Efficient Recombinant Protein Ligase.

scientific article published on 15 February 2017

Enzymatic Engineering of Live Bacterial Cell Surfaces Using Butelase 1.

scientific article published on 19 May 2017

Epitopic mapping of linear and conformation-dependent antigenic determinants on GP5 of five U.S. bluetongue viruses

scientific article published on 01 June 1992

Evaluation of the Effect of Trypsin Digestion Buffers on Artificial Deamidation

scientific article published on 22 December 2014

Expression of SARS-coronavirus envelope protein in Escherichia coli cells alters membrane permeability

scientific article published in December 2004

Formation of stable homodimer via the C-terminal alpha-helical domain of coronavirus nonstructural protein 9 is critical for its function in viral replication.

scientific article

Ginkgotides: Proline-Rich Hevein-Like Peptides from Gymnosperm Ginkgo biloba.

scientific article

Human Coronaviruses: A Review of Virus-Host Interactions.

scientific article published on 25 July 2016

Hypoxia-induced tumor exosomes promote M2-like macrophage polarization of infiltrating myeloid cells and microRNA-mediated metabolic shift

scientific article published on 12 March 2019

Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa.

scientific article published on 19 December 2016

Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein

scientific article published on 22 May 2018

Immobilization and Intracellular Delivery of Circular Proteins by Modifying a Genetically Incorporated Unnatural Amino Acid

scientific article published on 14 June 2018

Immobilized Peptide Asparaginyl Ligases Enhance Stability and Facilitate Macrocyclization and Site-Specific Ligation

scientific article published on 03 January 2020

Immunological detection and quantitation of alpha transforming growth factors in human breast carcinoma cells

article

Immunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea).

scientific article

Importance of SARS-CoV spike protein Trp-rich region in viral infectivity

scientific article published on 18 April 2008

Infertility induced in rats by immunization with synthetic peptide segments of a sperm protein

article

Inhibition of protein kinase R activation and upregulation of GADD34 expression play a synergistic role in facilitating coronavirus replication by maintaining de novo protein synthesis in virus-infected cells

scientific article published on 23 September 2009

Interaction of the coronavirus infectious bronchitis virus membrane protein with beta-actin and its implication in virion assembly and budding

scientific article

KLF4 suppresses HDACi induced caspase activation and the SAPK pathway by targeting p57(Kip2).

scientific article published in September 2009

LIR Motif-Containing Hyperdisulfide β-Ginkgotide is Cytoprotective, Adaptogenic, and Scaffold-Ready

scientific article published on 30 June 2019

Ligase-Controlled Cyclo-oligomerization of Peptides

scientific article published on 14 February 2019

Lipophilic multiple antigen peptide system for peptide immunogen and synthetic vaccine

scientific article published on 01 October 1994

Lybatides from Lycium barbarum Contain An Unusual Cystine-stapled Helical Peptide Scaffold

scientific article

Macrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin

scientific article

Marked Increase in Membranolytic Selectivity of Novel Cyclic Tachyplesins Constrained with an Antiparallel Two-β Strand Cystine Knot Framework

scientific article published on 01 January 2000

Membrane-Active Sequences within gp41 Membrane Proximal External Region (MPER) Modulate MPER-Containing Peptidyl Fusion Inhibitor Activity and the Biosynthesis of HIV-1 Structural Proteins

scientific article published on 31 July 2015

Membranolytic selectivity of cystine-stabilized cyclic protegrins

scientific article published on 01 June 2000

Methionine ligation strategy in the biomimetic synthesis of parathyroid hormones

scientific article published on 01 October 1998

Mimicking reverse protein splicing by three-segment tandem peptide ligation

scientific article published in November 2005

Molecular diversity and function of jasmintides from Jasminum sambac

scientific article published on 11 July 2018

Morintides: cargo-free chitin-binding peptides from Moringa oleifera

scientific article

Multiple antigen peptide system

scientific article published on January 1997

Multiple antigen peptide. A novel approach to increase detection sensitivity of synthetic peptides in solid-phase immunoassays

scientific article published in November 1989

Ninhydrin as a reversible protecting group of amino-terminal cysteine

scientific article published in March 2004

Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities

scientific article

One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1

scientific article published on 21 September 2018

Optimal oxidative folding of the novel antimicrobial cyclotide from Hedyotis biflora requires high alcohol concentrations

scientific article published on 25 July 2011

Oral administration of an antigenic synthetic lipopeptide (MAP-P3C) evokes salivary antibodies and systemic humoral and cellular responses.

scientific article

Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment

scientific article published on 24 April 2012

Oxidized Phospholipids, Lipoprotein(a), and Progression of Calcific Aortic Valve Stenosis

scientific article published on September 2015

Peptide segment ligation strategy without use of protecting groups.

scientific article published on July 1994

Peptide synthesis using unprotected peptides through orthogonal coupling methods

scientific article

Peptidomic Identification of Cysteine-Rich Peptides from Plants.

scientific article published in January 2018

Phenotyping of an in vitro model of ischemic penumbra by iTRAQ-based shotgun quantitative proteomics

scientific article

Plant-derived mitochondria-targeting cysteine-rich peptide modulates cellular bioenergetics

scientific article published on 23 January 2019

Plasma proteome coverage is increased by unique peptide recovery from sodium deoxycholate precipitate.

scientific article

Potentides: New Cysteine-Rich Peptides with Unusual Disulfide Connectivity from Potentilla anserina

scientific article published on 24 June 2019

Preparation of functionally active cell-permeable peptides by single-step ligation of two peptide modules

scientific article published on August 4, 1998

Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression

scientific article

Prooxidant modifications in the cryptome of beef jerky, the deleterious post-digestion composition of processed meat snacks

scientific article published on 19 July 2019

Pulsed SILAC-based proteomic analysis unveils hypoxia- and serum starvation-induced protein synthesis with PHD finger protein 14 (PHF14) as a hypoxia sensitive epigenetic regulator in cell cycle progression

scientific article published on 15 March 2019

Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction.

scientific article

Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis

scientific article

Quantitative profiling of the rat heart myoblast secretome reveals differential responses to hypoxia and re-oxygenation stress

scientific article published on 9 January 2014

Quaternary protein mimetics of gp41 elicit neutralizing antibodies against HIV fusion-active intermediate state.

scientific article

Recent advances in multiple antigen peptides

scientific article published on September 1996

Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus.

scientific article published on 28 September 2011

Roseltide rT7 is a disulfide-rich, anionic, and cell-penetrating peptide that inhibits proteasomal degradation

scientific article published on 14 November 2019

Selection of active ScFv to G-protein-coupled receptor CCR5 using surface antigen-mimicking peptides.

scientific article

Shope fibroma virus growth factor exhibits epidermal growth factor activities in newborn mice

scientific article

Simultaneous characterization of glyco- and phosphoproteomes of mouse brain membrane proteome with electrostatic repulsion hydrophilic interaction chromatography

scientific article

Site-Specific N-Terminal Labeling of Peptides and Proteins using Butelase 1 and Thiodepsipeptide

scientific article published on 13 November 2015

Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells.

scientific article published on April 1985

Structural determinants for peptide-bond formation by asparaginyl ligases

scientific article published on 23 May 2019

Studies on the Chitin Binding Property of Novel Cysteine-Rich Peptides from Alternanthera sessilis

scientific article published on 14 October 2015

Subtilisin-Catalyzed Synthesis of Amino Acid and Peptide Esters. Application in a Two-Step Enzymatic Ligation Strategy

scientific article published on 01 December 2001

Sumoylation of the Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus by Interaction with UBC9

scientific article published on 01 January 2006

Sumoylation of the nucleocapsid protein of severe acute respiratory syndrome coronavirus

scientific article

Synthesis of biologically active rat transforming growth factor I.

scientific article published on May 1984

Synthetic peptides as antigens for the detection of humoral immunity to Plasmodium falciparum sporozoites

scientific article published in October 1986

Tandem Thiol Switch Synthesis of Peptide Thioesters via N–S Acyl Shift on Thiazolidine

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Tandem ligation of multipartite peptides with cell-permeable activity

scientific article

Tandem ligation of unprotected peptides through thiaprolyl and cysteinyl bonds in water

scientific article published in March 2001

Tandem peptide ligation for synthetic and natural biologicals.

scientific article

The effect of salt on oligocation-induced chromatin condensation

scientific article published on 29 December 2011

The sequence and optical configuration of the amino acids xentoxin.

scientific article

Thiazolidine Formation as a General and Site-Specific Conjugation Method for Synthetic Peptides and Proteins

scientific article published on 01 January 1996

Total Synthesis of Circular Bacteriocins by Butelase 1.

scientific article published on 20 May 2016

Transforming growth factor is a potent stimulator of testicular ornithine decarboxylase in immature mouse

scientific article published on 01 November 1985

Translocating proline-rich peptides from the antimicrobial peptide bactenecin 7.

scientific article published on December 2002

Tryptophan-dependent membrane interaction and heteromerization with the internal fusion peptide by the membrane proximal external region of SARS-CoV spike protein.

scientific article

Tumorigenic poxviruses: characterization of the expression of an epidermal growth factor related gene in Shope fibroma virus

scientific article

Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication

scientific article

Vaccatides: Antifungal Glutamine-Rich Hevein-Like Peptides from Vaccaria hispanica

scientific article

Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes

scientific article

Vascular Bed Molecular Profiling by Differential Systemic Decellularization In Vivo

scientific article published on 01 October 2018

Viroporin Activity of SARS-CoV E Protein

article

[46] Multiple antigenic peptide method for producing antipeptide site-specific antibodies

scientific article published on 01 January 1989

β-Ginkgotides: Hyperdisulfide-constrained peptides from Ginkgo biloba.

scientific article published on 21 July 2017