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List of works by Silvano Ferrini

A multi-DNA preventive vaccine for p53/Neu-driven cancer syndrome

scientific article published in May 2009

A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing

scientific article published on September 2004

A novel surface molecule expressed by long-term cultured T and natural killer cells is involved in cell activation

scientific article published on September 1991

ADAM10 correlates with uveal melanoma metastasis and promotes in vitro invasion

scientific article published on 11 September 2014

Activated leukocyte cell adhesion molecule expression and shedding in thyroid tumors

scientific article

Activated leukocyte cell adhesion molecule soluble form: a potential biomarker of epithelial ovarian cancer is increased in type II tumors

scientific article published on 13 December 2012

An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease

scientific article

An interferon-sensitive response element is involved in constitutive caspase-8 gene expression in neuroblastoma cells.

scientific article published on January 2007

Anti-human thyroglobulin autoantibodies assayed by an enzyme-linked immunosorbent assay ⬇️

scientific article published on 01 April 1983

Anti-tumor efficacy of an anti-epidermal-growth-factor-receptor monoclonal antibody and its F(ab')2 fragment against high- and low-EGFR-expressing carcinomas in nude mice

scientific article

Antimetastatic Activity of a Preventive Cancer Vaccine

scientific article (publication date: 15 November 2007)

Arginase 2 is expressed by human lung cancer, but it neither induces immune suppression, nor affects disease progression

scientific article

Bispecific monoclonal antibodies directed to CD16 and to a tumor-associated antigen induce target-cell lysis by resting NK cells and by a subset of NK clones

scientific article published on May 1991

CD133-Positive Cells from Non-Small Cell Lung Cancer Show Distinct Sensitivity to Cisplatin and Afatinib

scientific article

CIITA-induced MHC class II expression in mammary adenocarcinoma leads to a Th1 polarization of the tumor microenvironment, tumor rejection, and specific antitumor memory.

scientific article published on June 2006

Caspase-8 gene expression in neuroblastoma.

scientific article

Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery

scientific article published on July 1987

Characterization of a cyclosporin A-sensitive activation pathway in cultured T and natural killer cells.

scientific article published on April 1994

Circulating T-cell subsets in Graves' disease: differences between patients with active disease and in remission after 131I-therapy.

scientific article

Context-dependent role of IL-18 in cancer biology and counter-regulation by IL-18BP.

scientific article published on 29 December 2014

Cyclosporin-A inhibits IL-2 production by all human T-cell clones having this function, independent of the phenotype or the coexpression of cytolytic activity

scientific article published on 01 January 1986

Cytolytic T lymphocytes displaying natural killer (NK)-like activity: expression of NK-related functional receptors for HLA class I molecules (p58 and CD94) and inhibitory effect on the TCR-mediated target cell lysis or lymphokine production.

scientific article published on April 1995

Detection of a functional hybrid receptor gammac/GM-CSFRbeta in human hematopoietic CD34+ cells.

scientific article

Different levels of control prevent interferon-gamma-inducible HLA-class II expression in human neuroblastoma cells

scientific article published on October 2003

Different subcellular localization of ALCAM molecules in neuroblastoma: Association with relapse.

scientific article

Different types of effector cells involved in non-mhc-restricted cytolytic activity

scientific article published on 01 July 1988

Differential STAT3, STAT5, and NF-kappaB activation in human hematopoietic progenitors by endogenous interleukin-15: implications in the expression of functional molecules

scientific article published on 6 March 2003

Differentiation Therapy: Targeting Human Renal Cancer Stem Cells with Interleukin 15

scientific article published on 31 October 2011

Drug delivery with a calixpyrrole--trans-Pt(II) complex

scientific article

Dual Roles of IL-27 in Cancer Biology and Immunotherapy

scientific article published on February 2017

Enhancement of the antitumor properties of interleukin-2 by its targeted delivery to the tumor blood vessel extracellular matrix

scientific article published on 01 March 2002

Exocytosis of azurophil and arginase 1-containing granules by activated polymorphonuclear neutrophils is required to inhibit T lymphocyte proliferation.

scientific article

Expression and methylation of CASP8 in neuroblastoma: identification of a promoter region

scientific article published on 01 December 2002

Expression of FOXP3, CD14, and ARG1 in Neuroblastoma Tumor Tissue from High-Risk Patients Predicts Event-Free and Overall Survival.

scientific article published on 16 June 2015

Expression of interleukin-18 in human ovarian carcinoma and normal ovarian epithelium: evidence for defective processing in tumor cells

scientific article

Expression of the caspase-8 gene in neuroblastoma cells is regulated through an essential interferon-sensitive response element (ISRE)

scientific article published on 01 January 2004

Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans

scientific article published in March 1999

Generation of a novel regulatory NK cell subset from peripheral blood CD34+ progenitors promoted by membrane-bound IL-15

scientific article

Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking

scientific article

Glioma immunotherapy by IL-21 gene-modified cells or by recombinant IL-21 involves antibody responses.

scientific article

Graves' disease: phenotypic and functional analysis at the clonal level of the T-cell repertoire in peripheral blood and in thyroid

scientific article published on 01 May 1988

HIV-1 Tat protein mimicry of chemokines

scientific article

Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells

scientific article

Human CD3+4-8-WT31- T lymphocyte populations expressing the putative T cell receptor gamma-gene product. A limiting dilution and clonal analysis

scientific article published on 01 September 1987

Human CD3-CD16+ natural killer cells express the hGATA-3 T cell transcription factor and an unrearranged 2.3-kb TcR delta transcript.

scientific article published on May 1993

Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions.

scientific article

Human T lymphocytes expressing gamma/delta T cell antigen receptor

scientific article published on 01 January 1989

Human renal cancer cells express a novel membrane-bound interleukin-15 that induces, in response to the soluble interleukin-15 receptor alpha chain, epithelial-to-mesenchymal transition

scientific article

IL-10 and ARG-1 concentrations in bone marrow and peripheral blood of metastatic neuroblastoma patients do not associate with clinical outcome.

scientific article published on 19 April 2015

IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions

scientific article

IL-15/IL-15R alpha intracellular trafficking in human cells and protection from apoptosis.

scientific article published on June 1999

IL-21: a pleiotropic cytokine with potential applications in oncology

scientific article published on 15 April 2015

IL-27 induces the expression of IDO and PD-L1 in human cancer cells

scientific article published on 9 December 2015

IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer

scientific article

Identification of GALNT14 as a novel neuroblastoma predisposition gene

scientific article published on 3 July 2015

Identification of a novel domain of HIV tat involved in monocyte chemotaxis

scientific article published in June 1998

Immunological imbalance in uncomplicated chronic alcoholism

scientific article published on 01 October 1983

Immunoprevention of HER-2/neu transgenic mammary carcinoma through an interleukin 12-engineered allogeneic cell vaccine

scientific article published in June 2004

Immunotherapeutic Applications of IL-15 ⬇️

scientific article published on September 1, 2012

Immunotherapy of neuroblastoma by an Interleukin-21-secreting cell vaccine involves survivin as antigen

scientific article published on 7 March 2008

In vitro and in vivo stability and anti-tumour efficacy of an anti-EGFR/anti-CD3 F(ab')2 bispecific monoclonal antibody

scientific article

Incidence of T cell subset imbalance in relatives of Graves' disease patients

scientific article published on 01 April 1984

Induction of anti-tumor immune response by bispecific monoclonal antibodies (bimAbs)

scientific article published on 01 September 1992

Interleukin (IL)-18, a biomarker of human ovarian carcinoma, is predominantly released as biologically inactive precursor

scientific article published on 6 January 2011

Interleukin 21 Controls mRNA and MicroRNA Expression in CD40-Activated Chronic Lymphocytic Leukemia Cells

scientific article published on 25 August 2015

Interleukin-15 is a major regulator of the cell-microenvironment interactions in human renal homeostasis.

scientific article published on 13 September 2012

Interleukin-15 liver gene transfer increases the number and function of IKDCs and NK cells.

scientific article published on 14 February 2008

Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

scientific article

Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells

scientific article

Internalization and recycling of ALCAM/CD166 detected by a fully human single-chain recombinant antibody

scientific article

Lack of HLA-class I antigens in human neuroblastoma cells: analysis of its relationship to TAP and tapasin expression

scientific article published on February 2001

Low doses of rIL2 after autologous bone marrow transplantation induce a "prolonged" immunostimulation of NK compartment in high-grade non-Hodgkin's lymphomas

scientific article

Magnetic resonance imaging at 1.5 T with immunospecific contrast agent in vitro and in vivo in a xenotransplant model

scientific article published on 12 December 2006

Mda-9/syntenin is expressed in uveal melanoma and correlates with metastatic progression

scientific article

Membrane-bound and soluble IL-15/IL-15Ralpha complexes display differential signaling and functions on human hematopoietic progenitors.

scientific article published on 23 June 2005

Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence.

scientific article published in February 2018

NK cells provide helper signal for CD8+ T cells by inducing the expression of membrane-bound IL-15 on DCs.

scientific article published on 26 March 2009

New perspectives for the pharmacological and biological therapy of small cell lung cancer.

scientific article

New perspectives in glioma immunotherapy.

scientific article published on January 2011

New immunotherapeutic strategies for the treatment of neuroblastoma

scientific article published on January 2015

Phenotypic and functional analysis of human CD3+ and CD3- clones with "lymphokine-activated killer" (LAK) activity. Frequent occurrence of CD3+ LAK clones which produce interleukin-2

scientific article published on 01 October 1987

Potent arylsulfonamide inhibitors of tumor necrosis factor-alpha converting enzyme able to reduce activated leukocyte cell adhesion molecule shedding in cancer cell models

scientific article

Potential Role of Soluble c-Met as a New Candidate Biomarker of Metastatic Uveal Melanoma

scientific article published on 11 June 2015

Prevention of angiogenesis by naked DNA IL-12 gene transfer: angioprevention by immunogene therapy.

scientific article published in February 2004

Prevention of spontaneous neu-expressing mammary tumor development in mice transgenic for rat proto-neu by DNA vaccination.

scientific article published in January 2001

Prolactin secretion in pubertal and adult male subjects

scientific article published on 01 June 1984

Re-targeting of human lymphocytes expressing the T-cell receptor gamma/delta to ovarian carcinoma cells by the use of bispecific monoclonal antibodies

article published in 1989

Recombinant IL-21 and anti-CD4 antibodies cooperate in syngeneic neuroblastoma immunotherapy and mediate long-lasting immunity

scientific article

Role of CXCL13-CXCR5 crosstalk between malignant neuroblastoma cells and Schwannian stromal cells in neuroblastic tumors.

scientific article

Role of IL-21 in immune-regulation and tumor immunotherapy

scientific article published on 20 April 2007

Role of common-gamma chain cytokines in NK cell development and function: perspectives for immunotherapy.

scientific article

Role of methylation in the control of DeltaNp73 expression in neuroblastoma

scientific article published on 01 March 2002

Selective arylsulfonamide inhibitors of ADAM-17: hit optimization and activity in ovarian cancer cell models

scientific article published on 4 October 2013

Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibility

scientific article

Strategies for improving the water solubility of new antitumour nitronaphthylbutadiene derivatives.

scientific article published on 11 October 2010

Study of bioassayable somatomedin on renal artery and vein

scientific article published on 01 July 1979

Subcellular Localization of Activated Leukocyte Cell Adhesion Molecule Is a Molecular Predictor of Survival in Ovarian Carcinoma Patients

scientific article published on 01 March 2008

Suramin-induced growth inhibition and insulin-like growth factor-I binding blockade in human breast carcinoma cell lines: potentially related events

scientific article published on 01 January 1993

Surface markers of human lymphokine-activated killer cells and their precursors. Analysis at the population and clonal level

scientific article published on 01 January 1987

T cell clones expressing the natural killer cell-related p58 receptor molecule display heterogeneity in phenotypic properties and p58 function

scientific article published on October 1994

Targeting Tumor-Related Immunosuppression for Cancer Immunotherapy

scientific article

Targeting cancer-initiating cell drug-resistance: a roadmap to a new-generation of cancer therapies?

scientific article published on 21 February 2011

Targeting of T lymphocytes against EGF-receptor+ tumor cells by bispecific monoclonal antibodies: requirement of CD3 molecule cross-linking for T-cell activation

scientific article published on December 1993

Targeting of saporin to CD25-positive normal and neoplastic lymphocytes by an anti-saporin/anti-CD25 bispecific monoclonal antibody: in vitro evaluation

scientific article

Targeting of saporin to Hodgkin's lymphoma cells by anti-CD30 and anti-CD25 bispecific antibodies

scientific article published on 01 September 1998

The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cells

scientific article published on December 2007

The IL-18 antagonist IL-18-binding protein is produced in the human ovarian cancer microenvironment

scientific article published on 19 July 2013

The LFA-1/ICAM cell adhesion pathway is involved in tumor-cell lysis mediated by bispecific monoclonal-antibody-targeted T lymphocytes

scientific article published on 01 March 1994

The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways

scientific article

The redox state of the lung cancer microenvironment depends on the levels of thioredoxin expressed by tumor cells and affects tumor progression and response to prooxidants.

scientific article published in October 2008

Transient depletion of CD4(+) T cells augments IL-21-based immunotherapy of disseminated neuroblastoma in syngeneic mice.

scientific article published in September 2010

Tumor rejection by gene transfer of the MHC class II transactivator in murine mammary adenocarcinoma cells.

scientific article published on May 2003

Two-step in vivo tumor targeting by biotin-conjugated antibodies and superparamagnetic nanoparticles assessed by magnetic resonance imaging at 1.5 T.

scientific article published on 6 October 2009

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