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List of works by Hidemitsu Nakajima

A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon

scientific article published on 23 February 2007

A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 [2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one]: pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats

scientific article published in October 2004

A rapid, targeted, neuron-selective, in vivo knockdown following a single intracerebroventricular injection of a novel chemically modified siRNA in the adult rat brain

scientific article published on 06 November 2011

Activation of cultured astrocytes by amphotericin B: stimulation of NO and cytokines production and changes in neurotrophic factors production.

scientific article published on 28 May 2013

Active site cysteine-null glyceraldehyde-3-phosphate dehydrogenase (GAPDH) rescues nitric oxide-induced cell death

scientific article

Adenosine and ATP affect LPS-induced cytokine production in canine macrophage cell line DH82 cells.

scientific article

Amphotericin B induces glial cell line-derived neurotrophic factor in the rat brain

scientific article published on 3 October 2014

An aggregate-prone mutant of human glyceraldehyde-3-phosphate dehydrogenase augments oxidative stress-induced cell death in SH-SY5Y cells

scientific article published on 27 October 2009

Botulinum neurotoxin A subtype 2 reduces pathological behaviors more effectively than subtype 1 in a rat Parkinson's disease model

scientific article published on 5 April 2014

Botulinum neurotoxin type A subtype 2 confers greater safety than subtype 1 in a rat Parkinson's disease model

scientific article published on 21 May 2014

Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery.

scientific article

Critical role of the automodification of poly(ADP-ribose) polymerase-1 in nuclear factor-kappaB-dependent gene expression in primary cultured mouse glial cells.

scientific article

Differences in time to peak carbachol-induced contractions between circular and longitudinal smooth muscles of mouse ileum

scientific article published on 16 October 2015

Distribution and immunohistochemical localization of GDNF protein in selected neural and non-neural tissues of rats during development and changes in unilateral 6-hydroxydopamine lesions

scientific article published on August 2007

Drug delivery system for poorly water-soluble compounds using lipocalin-type prostaglandin D synthase

scientific article

Effects of Amphotericin B on the expression of neurotoxic and neurotrophic factors in cultured microglia

scientific article

Evidence that nitric oxide is a non-adrenergic non-cholinergic inhibitory neurotransmitter in the circular muscle of the mouse distal colon: a study on the mechanism of nitric oxide-induced relaxation

scientific article published on 13 September 2014

Extracellular poly(ADP-ribose) is a neurotrophic signal that upregulates glial cell line-derived neurotrophic factor (GDNF) levels in vitro and in vivo.

scientific article published on 24 January 2017

Functional interactions between the SK2 channel and the nicotinic acetylcholine receptor in enteric neurons of the guinea pig ileum

scientific article published on 22 October 2007

Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Aggregation Causes Mitochondrial Dysfunction during Oxidative Stress-induced Cell Death.

scientific article published on 06 February 2017

Glyceraldehyde-3-phosphate Dehydrogenase Aggregates Accelerate Amyloid-β Amyloidogenesis in Alzheimer Disease

scientific article published on 10 September 2015

Glyceraldehyde-3-phosphate dehydrogenase aggregate formation participates in oxidative stress-induced cell death

scientific article published on 16 October 2009

Glyceraldehyde-3-phosphate dehydrogenase aggregation inhibitor peptide: A potential therapeutic strategy against oxidative stress-induced cell death

scientific article published on 29 September 2015

Inhibitory effects of alendronate on cholinergic responses in rat lower esophageal sphincter

scientific article published on 18 March 2006

Interleukin 19 reduces inflammation in chemically induced experimental colitis

scientific article published on 23 October 2015

Interleukin-19 contributes as a protective factor in experimental Th2-mediated colitis

scientific article published on 9 December 2016

Interleukin-19 protects mice from innate-mediated colonic inflammation

scientific article published on 01 June 2010

Involvement of M(2) muscarinic receptors in relaxant response of circular muscle of mouse gastric antrum

scientific article published in March 2006

Involvements of PHI-nitric oxide and PACAP-BK channel in the sustained relaxation of mouse gastric fundus

scientific article published on 5 June 2008

Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death ⬇️

scientific article published on April 1, 2012

M2 and M3 muscarinic receptors are involved in enteric nerve-mediated contraction of the mouse ileum: Findings obtained with muscarinic-receptor knockout mouse

scientific article published on 28 September 2006

Na(+) /Ca(2+) exchanger 2-heterozygote knockout mice display decreased acetylcholine release and altered colonic motility in vivo

scientific article published on 17 October 2012

Na(+) /Ca(2+) exchanger-heterozygote knockout mice display increased relaxation in gastric fundus and accelerated gastric transit in vivo

scientific article published on 19 January 2016

Na+/Ca2+ exchanger contributes to stool transport in mice with experimental diarrhea.

scientific article

Na/Ca(2+) exchanger 1 transgenic mice display increased relaxation in the distal colon.

scientific article published on 26 November 2014

Na⁺/Ca²⁺ exchanger 1/2 double-heterozygote knockout mice display increased nitric oxide component and altered colonic motility

scientific article published on 26 October 2013

Nitric oxide and carbon monoxide act as inhibitory neurotransmitters in the longitudinal muscle of C57BL/6J mouse distal colon

scientific article published on 30 January 2010

Nuclear-translocated Glyceraldehyde-3-phosphate Dehydrogenase Promotes Poly(ADP-ribose) Polymerase-1 Activation during Oxidative/Nitrosative Stress in Stroke

scientific article

Orexin A affects ascending contraction depending on downstream cholinergic neurons and descending relaxation through independent pathways in mouse jejunum

scientific article published on 08 June 2006

Overexpression of Na+/Ca2+ exchanger 1 display enhanced relaxation in the gastric fundus.

scientific article published on 20 October 2016

PACAP provides colonic protection against dextran sodium sulfate induced colitis

scientific article

PPARα contributes to colonic protection in mice with DSS-induced colitis

scientific article published on 31 July 2010

Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascade

scientific article

Roles of Na(+)/Ca(2+) exchanger isoforms NCX1 and NCX2 in motility in mouse ileum

scientific article published on 14 July 2016

Synthesis and biological activities of novel furo[2,3,4-jk][2]benzazepin-4(3H)-one derivatives

scientific article published on 18 January 2007

The active site cysteine of the proapoptotic protein glyceraldehyde-3-phosphate dehydrogenase is essential in oxidative stress-induced aggregation and cell death

scientific article published on 05 July 2007

The role of muscarinic receptor subtypes in acetylcholine release from urinary bladder obtained from muscarinic receptor knockout mouse

scientific article published on 6 August 2008

Water-soluble ferulic acid derivatives improve amyloid-β-induced neuronal cell death and dysmnesia through inhibition of amyloid-β aggregation

scientific article published on 5 November 2015

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