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List of works by Peter Fedorocko

3,6-bis(3-alkylguanidino)acridines as DNA-intercalating antitumor agents

scientific article published on 23 September 2012

Administration of the bacterial extract Broncho-Vaxom enhances radiation recovery and myelopoietic regeneration

scientific article published in September 1994

Antitumor effect of the combination of manumycin A and Immodin is associated with antiplatelet activity and increased granulocyte tumor infiltration in a 4T1 breast tumor model.

scientific article published on 22 November 2016

Breast cancer resistance protein is the enemy of hypericin accumulation and toxicity of hypericin-mediated photodynamic therapy

scientific article published on 27 November 2018

Combined modality radioprotection: enhancement of survival and hematopoietic recovery in gamma-irradiated mice by the joint use of liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) and indomethacin

scientific article published on 01 May 1996

Conjunction of glutathione level, NAD(P)H/FAD redox status and hypericin content as a potential factor affecting colon cancer cell resistance to photodynamic therapy with hypericin.

scientific article published on 25 May 2013

Cytotoxic activity of proflavine diureas: synthesis, antitumor, evaluation and DNA binding properties of 1',1''-(acridin-3,6-diyl)-3',3''-dialkyldiureas

scientific article published on 19 January 2008

DNA-protective activities of hyperforin and aristoforin

scientific article published on 9 February 2015

Degradation of HER2 receptor through hypericin-mediated photodynamic therapy

scientific article

Downregulation of BCRP and anti-apoptotic proteins by proadifen (SKF-525A) is responsible for the enhanced mitoxantrone accumulation and toxicity in mitoxantrone-resistant human promyelocytic leukemia cells

scientific article published on 6 August 2015

Drug efflux transporters, MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells.

scientific article published on 23 October 2009

Drug membrane transporters and CYP3A4 are affected by hypericin, hyperforin or aristoforin in colon adenocarcinoma cells

scientific article published on 8 April 2016

Effect of acetazolamide on hypericin photocytotoxicity

scientific article published in July 2002

Enhanced antiproliferative and apoptotic response of HT-29 adenocarcinoma cells to combination of photoactivated hypericin and farnesyltransferase inhibitor manumycin A

scientific article published on 29 November 2011

Erythropoietin inhibits apoptosis induced by photodynamic therapy in ovarian cancer cells

scientific article

Flow cytometric determination of 5-bromo-2'-deoxyuridine pharmacokinetics in blood serum after intraperitoneal administration to rats and mice.

scientific article published on 25 July 2014

Histomorphological changes in murine fibrosarcoma after hypericin-based photodynamic therapy

scientific article

Histone deacetylase inhibitors potentiate photodynamic therapy in colon cancer cells marked by chromatin-mediated epigenetic regulation of CDKN1A.

scientific article

Human erythropoietin increases the pro-angiogenic potential of A2780 ovarian adenocarcinoma cells under hypoxic conditions.

scientific article published on 26 June 2013

Hypericin affects cancer side populations via competitive inhibition of BCRP.

scientific article published on 20 February 2018

Hypericin in the Light and in the Dark: Two Sides of the Same Coin

scientific article

Hypericin-induced photocytotoxicity is connected with G2/M arrest in HT-29 and S-phase arrest in U937 cells

scientific article published on September 2006

Hypericin-mediated photocytotoxic effect on HT-29 adenocarcinoma cells is reduced by light fractionation with longer dark pause between two unequal light doses

scientific article

Imunomodulative effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) on mice with alveolar echinococcosis and treated with albendazole

scientific article published on 29 June 2008

In vitro proliferation of fibrosarcoma cells depends on intact functions of lipoxygenases and cytochrome P-450-monooxygenase

scientific article

Influence of age and K, Mg aspartate (Cardilan) on murine haemopoiesis

scientific article published on 01 November 2000

Inhibition of DNA topoisomerases I and II and growth inhibition of HL-60 cells by novel acridine-based compounds.

scientific article published on 8 May 2015

Inhibition of GSK-3β reverses the pro-apoptotic effect of proadifen (SKF-525A) in HT-29 colon adenocarcinoma cells.

scientific article published on 7 June 2012

Interaction of cholinesterase modulators with DNA and their cytotoxic activity.

scientific article published in December 2013

Irradiation induces increased production of haemopoietic and proinflammatory cytokines in the mouse lung

scientific article published on 01 April 2002

Lichen secondary metabolites are responsible for induction of apoptosis in HT-29 and A2780 human cancer cell lines.

scientific article published on 21 January 2012

Liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) promotes haemopoietic recovery in irradiated mouse

scientific article published on 01 April 1994

Location and the functionality of erythropoietin receptor(s) in A2780 cells

scientific article published on 30 April 2012

Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin

scientific article

Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells.

scientific article published in September 2007

NF-κB is not directly responsible for photoresistance induced by fractionated light delivery in HT-29 colon adenocarcinoma cells

scientific article published on 12 August 2010

Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin

scientific article

New spiro tria(thia)zolidine-acridines as topoisomerase inhibitors, DNA binders and cytostatic compounds

scientific article published on 6 February 2016

Novel Insights into the Effect of Hyperforin and Photodynamic Therapy with Hypericin on Chosen Angiogenic Factors in Colorectal Micro-Tumors Created on Chorioallantoic Membrane

scientific article published on 19 June 2019

Novel trisubstituted acridines as human telomeric quadruplex binding ligands.

scientific article published on 10 August 2014

PUFAs enhance oxidative stress and apoptosis in tumour cells exposed to hypericin-mediated PDT.

scientific article published on 12 August 2010

Peroral administration of 5-bromo-2-deoxyuridine in drinking water is not a reliable method for labeling proliferating S-phase cells in rats.

scientific article published on 2 June 2015

Photodynamic therapy of murine fibrosarcoma with topical and systemic administration of hypericin.

scientific article

Photoinduced antitumour effect of hypericin can be enhanced by fractionated dosing.

scientific article

Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells.

scientific article published on 20 December 2005

Potentiality, Limitations, and Consequences of Different Experimental Models to Improve Photodynamic Therapy for Cancer Treatment in Relation to Antiangiogenic Mechanism

scientific article published on 30 July 2020

Potentiation of hypericin-mediated photodynamic therapy cytotoxicity by MK-886: focus on ABC transporters, GDF-15 and redox status.

scientific article published on 20 May 2015

Pre-treatment of HT-29 cells with 5-LOX inhibitor (MK-886) induces changes in cell cycle and increases apoptosis after photodynamic therapy with hypericin

scientific article

Proadifen sensitizes resistant ovarian adenocarcinoma cells to cisplatin.

scientific article published on 22 December 2015

Procedure for improved cleaning of FACSAria cuvette flow cell.

scientific article

Pulmonary fibroblasts stimulate the proliferation of cell lines from human lung adenocarcinomas

scientific article published on August 2006

Radioprotection of haemopoietic stem cells by a single injection of bacterial lysate - IRS-19 administered to mice before or after irradiation

scientific article published on 01 November 2000

Radioprotection of mice by the bacterial extract Broncho-Vaxom: haemopoietic stem cells and survival enhancement

scientific article published in April 1992

Radioprotective effects of WR-2721, Broncho-Vaxom and their combinations: survival, myelopoietic restoration and induction of colony-stimulating activity in mice

scientific article published on 01 February 1994

Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in rats

scientific article published on November 2014

Single pre-treatment with hypericin, a St. John's wort secondary metabolite, attenuates cisplatin- and mitoxantrone-induced cell death in A2780, A2780cis and HL-60 cells.

scientific article

Tacrine derivatives as dual topoisomerase I and II catalytic inhibitors.

scientific article

The effect of nonsteroidal antiinflammatory drugs ibuprofen, flurbiprofen, and diclofenac on in vitro and in vivo growth of mouse fibrosarcoma

scientific article published in January 2002

The role of p53 in the efficiency of photodynamic therapy with hypericin and subsequent long-term survival of colon cancer cells.

scientific article published on 10 September 2009

Tumor-host interactions accompanying the growth of the G:5:113 fibrosarcoma in the mouse: possibilities for a new therapeutic approach?

scientific article published on 01 April 2003

Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid ⬇️

scientific article published on September 17, 2010

YM155, a small molecule inhibitor of survivin expression, sensitizes cancer cells to hypericin-mediated photodynamic therapy.

scientific article published on 31 May 2016

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