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List of works by Karl J Tronstad

A Bioactively Modified Fatty Acid Improves Survival and Impairs Metastasis in Preclinical Models of Acute Leukemia

scientific article published on 01 June 2006

A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

scientific article

Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures

scientific article published in November 2002

Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action?

scientific article

Automated quantification and integrative analysis of 2D and 3D mitochondrial shape and network properties

scientific article

Axl-inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model ⬇️

scientific article published on 05 July 2021

BMET-34DRUG REPURPOSING DISCOVERS BETA-SITOSTEROL AS AN EFFECTIVE THERAPEUTIC AGENT AGAINST MELANOMA BRAIN METASTASES IN VIVO.

scientific article

Camptothecin and khat (Catha edulis Forsk.) induced distinct cell death phenotypes involving modulation of c-FLIPL, Mcl-1, procaspase-8 and mitochondrial function in acute myeloid leukemia cell lines

scientific article

Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression: evidence for peroxisome proliferator-activated rec

scientific article published on 19 May 2003

Connexin-based signaling in acute myelogenous leukemia (AML).

scientific article published on 31 October 2009

Corrigendum: A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology

scientific article published on 19 August 2016

Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC.

scientific article published in June 2019

Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial function

scientific article published on 29 July 2016

Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status

scientific article

Human TNF-alpha in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes

scientific article published on 18 July 2002

Hyperoxia increases the uptake of 5-fluorouracil in mammary tumors independently of changes in interstitial fluid pressure and tumor stroma

scientific article

Hyperoxic treatment induces mesenchymal-to-epithelial transition in a rat adenocarcinoma model

scientific article

Impact of mitochondrial beta-oxidation in fatty acid-mediated inhibition of glioma cell proliferation

scientific article

In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation.

scientific article published in October 1999

In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum

scientific article published on 18 March 2005

Increased hepatic mitochondrial FA oxidation reduces plasma and liver TG levels and is associated with regulation of UCPs and APOC-III in rats.

scientific article published on 4 May 2017

Induction of mitochondrial biogenesis and respiration is associated with mTOR regulation in hepatocytes of rats treated with the pan-PPAR activator tetradecylthioacetic acid (TTA)

scientific article published on 07 December 2012

Introducing nano-scale quantitative polymerase chain reaction

scientific article published on 02 November 2018

Is targeted chemotherapy an alternative to immunotherapy in chronic lymphocytic leukemia?

scientific article

Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats

scientific article

Metabolic effects of 3-thia fatty acid in cancer cells

scientific article published on 01 January 1999

Metabolic effects of thia fatty acids

scientific article

Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells

scientific article published on 18 May 2021

Mitochondrial-targeted fatty acid analog induces apoptosis with selective loss of mitochondrial glutathione in promyelocytic leukemia cells

scientific article published in July 2003

Modified fatty acids and their possible therapeutic targets in malignant diseases ⬇️

scientific article published on October 1, 2003

Neural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality

scientific article published on 11 April 2019

Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth

scientific article

Peptide-mediated delivery of donor mitochondria improves mitochondrial function and cell viability in human cybrid cells with the MELAS A3243G mutation

scientific article published on 6 September 2017

Poorly oxidizable fatty acid analogues inhibit the proliferation of cancer cells in culture

scientific article published on 01 January 1999

Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB.

scientific article published on 27 September 2009

Protein lysine acetylation in normal and leukaemic haematopoiesis: HDACs as possible therapeutic targets in adult AML.

scientific article

Regulation and quantification of cellular mitochondrial morphology and content.

scientific article published on January 2014

Subcellular Distribution of NAD+ between Cytosol and Mitochondria Determines the Metabolic Profile of Human Cells.

scientific article

Targeting mitochondria in the treatment of human cancer: a coordinated attack against cancer cell energy metabolism and signalling

scientific article published on August 2007

Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways

scientific article

Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance.

scientific article

The angiogenic switch leads to a metabolic shift in human glioblastoma

scientific article published on 3 September 2016

The metabolic syndrome and the hepatic fatty acid drainage hypothesis.

scientific article

Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide

scientific article published on 11 December 2018

Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation

scientific article published on 25 July 2019

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