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List of works by Kai Ge

53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.

scientific article

A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex

scientific journal article

Affinity purification of MLL3/MLL4 histone H3K4 methyltransferase complex

scientific article

An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth.

scientific article

Bin2, a functionally nonredundant member of the BAR adaptor gene family

scientific article published in July 2000

Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.

scientific article published on 20 December 2017

Cloning of Glial Cell Line-derived Neurotrophic Factor Gene and Its Expression in Eukaryotic Cells

scientific article published on January 1999

Construction of Two AFP-positive Hepatoma Cell-specific Gene Regulatory Sequences

scientific article published on 01 January 1998

Constructure of a recombinant adenovirus vector with HSV-TK and it's killer effect on tumor cells in vitro

scientific article published in September 1998

DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier

scientific article published on 27 July 2014

Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.

scientific article published on 4 May 2018

Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.

scientific article

Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor γ in Adipogenesis

scientific article published on 24 October 2016

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

scientific article

EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR

scientific article

Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition

scientific article

Epigenetic regulation of adipogenesis by histone methylation.

scientific article published on 4 January 2012

Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.

scientific article

Experimental treatment for human colorectal carcinoma by tissue type specific expression of herpes simplex virus thymidine kinase gene

scientific article published in September 1998

Expression of Brain-derived Neurotrophic Factor (BDNF) Gene in Rat Myoblast Cells.

scientific article published on January 1999

Expression of Cytosine Deaminase Gene in Human Colon Carcinoma Cells by Recombinant Retroviral Vector.

scientific article published on January 1997

Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid β-oxidation

scientific article published on 18 June 2018

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

scientific article

Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis

scientific article

Genetic analysis of adipogenesis through peroxisome proliferator-activated receptor gamma isoforms

scientific article published on 27 August 2002

Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways

scientific article

Glucocorticoid Receptor Accelerates, but Is Dispensable for, Adipogenesis

scientific article published on 24 October 2016

H2A.Z facilitates access of active and repressive complexes to chromatin in embryonic stem cell self-renewal and differentiation.

scientific article published on 20 December 2012

H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development

article

H3.3K4M destabilizes enhancer epigenomic writers MLL3/4 and impairs adipose tissue development

article

H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability.

scientific article

H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

scientific article

Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer

scientific article

High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase

scientific article published on 11 July 2019

Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms.

scientific article published on 23 May 2016

Histone H3 lysine 4 methyltransferase KMT2D.

scientific article published on 29 June 2017

Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.

scientific article published on 9 January 2018

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis.

scientific article

Histone demethylases UTX and JMJD3 are required for NKT cell development in mice

scientific article

Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches

article published in the Proceedings of the National Academy of Sciences of the United States of America

Identification of H3K4me1-associated proteins at mammalian enhancers

scientific article published on 18 December 2017

In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis

scientific article published on 9 April 2018

Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration

scientific article published on 13 July 2020

Loss of function of mouse Pax-Interacting Protein 1-associated glutamate rich protein 1a (Pagr1a) leads to reduced Bmp2 expression and defects in chorion and amnion development

scientific journal article

Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma

scientific article published on 01 April 2000

Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity

article

Lysine demethylase KDM6A in differentiation, development and cancer

scientific article published on 17 August 2020

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis

scientific article

MLL3/MLL4-associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPβ and C/EBPδ

scientific article published on 29 June 2020

MLL4 mediates differentiation and tumor suppression through ferroptosis

scientific article published on 10 December 2021

MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping

scientific article published on 31 July 2017

Mammary-Stem-Cell-Based Somatic Mouse Models Reveal Breast Cancer Drivers Causing Cell Fate Dysregulation

scientific article published on September 2016

Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma.

scientific article

PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex

scientific article

PTIP promotes chromatin changes critical for immunoglobulin class switch recombination

scientific journal article

Replication fork stability confers chemoresistance in BRCA-deficient cells

scientific article

Role of mediator in transcriptional activation by the aryl hydrocarbon receptor

scientific article published on 16 January 2004

Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF

scientific article published on 24 May 2019

Spatial clustering for identification of ChIP-enriched regions (SICER) to map regions of histone methylation patterns in embryonic stem cells

scientific article

Suicide gene therapy for glioma using HSV-tk/GCV system

scientific article published in September 1997

T3 and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice.

scientific article

Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation.

scientific article

The Construction of an Adenovirus Vector Containing Cytosine Deaminase Gene and Its Application.

scientific article

The DNA damage- and transcription-associated protein paxip1 controls thymocyte development and emigration.

scientific article

The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis ⬇️

scientific article published on October 1, 2003

The c-Myc-interacting adaptor protein Bin1 activates a caspase-independent cell death program

scientific article published on 01 September 2000

The use of suicide gene systems in vascular cells in vitro

scientific article published on March 1998

Thyroid hormone-induced juxtaposition of regulatory elements/factors and chromatin remodeling of Crabp1 dependent on MED1/TRAP220.

scientific article published on September 2005

Transcriptional and Epigenomic Regulation of Adipogenesis

scientific article published on 14 May 2019

Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis

scientific article

Transduction of cytosine deaminase gene makes rat glioma cells highly sensitive to 5-fluorocytosine

scientific article published on May 1997

UTX demethylase activity is required for satellite cell-mediated muscle regeneration

scientific article published on 21 March 2016

UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia

scientific article published on March 2016

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

scientific journal article

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity ⬇️

scientific article published on September 4, 2012

UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.

scientific article

Use of Carcinoembryonic Antigen Gene Promoter in Colorectal Carcinoma-specific Suicidal Gene Therapy.

scientific article published on January 1998

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