List of works - Núria Verdaguer

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

scientific article

A comparison of viral RNA-dependent RNA polymerases

scientific article published on 20 December 2005

A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules

scientific article

A novel benzonitrile analogue inhibits rhinovirus replication

scientific article

A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation

scientific article published on January 1998

Activation mechanism of a noncanonical RNA-dependent RNA polymerase

scientific article

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

scientific article

Antigenically profound amino acid substitutions occur during large population passages of foot-and-mouth disease virus

scientific article published in November 1996

Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein

scientific article

Biochemical and structural studies with neutralizing antibodies raised against foot-and-mouth disease virus.

scientific article

Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication ⬇️

scientific article

Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine

scientific article

Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus

scientific article published on 29 September 2011

Conformational changes in motif D of RdRPs as fidelity determinant.

scientific article

Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage

scientific article

Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site

scientific article published on 28 August 2019

Crystal structure of catalase HPII from Escherichia coli

scientific article

Crystallization and preliminary X-ray analysis of clade I catalases from Pseudomonas syringae and Listeria seeligeri.

scientific article published on 23 July 2001

Crystallization and preliminary X-ray analysis of human rhinovirus serotype 2 (HRV2)

scientific article published on 01 August 1999

Crystallization and preliminary X-ray analysis of swine vesicular disease virus (SVDV).

scientific article published on 21 February 2003

Crystallization and preliminary X-ray analysis of the glycogen synthase from Pyrococcus abyssi

scientific article

Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.

scientific article published on September 1996

Cyclic peptides as conformationally restricted models of viral antigens: application to foot-and-mouth disease virus.

scientific article published in January 1995

Decrease in pH destabilizes individual vault nanocages by weakening the inter-protein lateral interaction.

scientific article

Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding

scientific article published on December 1997

Epitope insertion at the N-terminal molecular switch of the rabbit hemorrhagic disease virus T = 3 capsid protein leads to larger T = 4 capsids

scientific article

Evolution of cell recognition by viruses: a source of biological novelty with medical implications

scientific article published on January 2003

Evolution subverting essentiality: dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus.

scientific article

Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: structure and neutralisation

scientific article

Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth-disease virus

scientific article published in February 1996

Infectious Bursal Disease Virus VP3 Upregulates VP1-Mediated RNA-Dependent RNA Replication

scientific article published on 26 August 2015

Infectious bursal disease virus capsid assembly and maturation by structural rearrangements of a transient molecular switch

scientific article published on 18 April 2007

Insights into minor group rhinovirus uncoating: the X-ray structure of the HRV2 empty capsid

scientific article (publication date: 2012)

Mechanical stability and reversible fracture of vault particles

scientific article

Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition

scientific article

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

scientific article

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition

scientific article published on 22 April 2015

Multiple virulence determinants of foot-and-mouth disease virus in cell culture

scientific article published on August 1998

Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding

scientific article

New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach

scientific article

Preliminary analysis of two and three dimensional crystals of vault ribonucleoprotein particles

article

Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.

scientific article published in May 2002

Purification, crystallization and preliminary X-ray diffraction analysis of the RNA-dependent RNA polymerase from Thosea asigna virus

scientific article published on 29 September 2012

RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

scientific article (publication date: August 2015)

Rapid selection in modified BHK-21 cells of a foot-and-mouth disease virus variant showing alterations in cell tropism

scientific article published on December 1998

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

scientific article published in July 2003

Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activity

scientific article published on 28 March 2013

SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations

scientific article published on 8 June 2022

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

scientific article published on 29 March 2022

Sequential structures provide insights into the fidelity of RNA replication

scientific article

Structural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2

scientific article

Structural basis for host membrane remodeling induced by protein 2B of hepatitis A virus

scientific article

Structural characterization of the Rabphilin-3A-SNAP25 interaction

scientific article published on 20 June 2017

Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase

scientific article

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

scientific article

Structural insights into the multifunctional protein VP3 of birnaviruses

scientific article

Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG)

scientific article

Structure and dsRNA-binding activity of the Birnavirus Drosophila X Virus VP3 protein

scientific article published on 25 November 2020

Structure and function of the NS5 methyltransferase domain from Usutu virus

scientific article published in December 2022

Structure and supramolecular packing features of the dipeptide Arg-Val acetate

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

scientific article

Structure of Swine Vesicular Disease Virus: Mapping of Changes Occurring during Adaptation of Human Coxsackie B5 Virus To Infect Swine

scientific article

Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation

scientific article published on 18 May 2017

Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.

scientific article published on 3 August 2004

Structure of human rhinovirus serotype 2 (HRV2)

scientific article

Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains

scientific article

Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop

scientific article published on April 1997

Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction

scientific article published on April 1995

Supramolecular arrangement of the full-length Zika virus NS5

scientific article published on 05 April 2019

The 2.6-Angstrom structure of infectious bursal disease virus-derived T=1 particles reveals new stabilizing elements of the virus capsid

scientific article published on July 2006

The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

scientific article

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

scientific article

The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases

scientific article

The T=1 capsid protein of Penicillium chrysogenum virus is formed by a repeated helix-rich core indicative of gene duplication.

scientific article

The coat protein of Rabbit hemorrhagic disease virus contains a molecular switch at the N-terminal region facing the inner surface of the capsid.

scientific article published on April 2004

The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP

scientific article

The need for a shared database infrastructure: combining X-ray crystallography and electron microscopy

scientific article published on January 2000

The structure of a protein primer-polymerase complex in the initiation of genome replication

scientific article

Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle

scientific article

Vault particles: a new generation of delivery nanodevices.

scientific article published on 06 June 2012

Viruses and viral proteins

scientific article published on 14 October 2014

X-ray crystallography of viruses

scientific article published on January 2013

X-ray structure of a minor group human rhinovirus bound to a fragment of its cellular receptor protein

scientific article published on 4 April 2004

List of works by Núria Verdaguer

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

A comparison of viral RNA-dependent RNA polymerases

A multiply substituted G-H loop from foot-and-mouth disease virus in complex with a neutralizing antibody: a role for water molecules

A novel benzonitrile analogue inhibits rhinovirus replication

A similar pattern of interaction for different antibodies with a major antigenic site of foot-and-mouth disease virus: implications for intratypic antigenic variation

Activation mechanism of a noncanonical RNA-dependent RNA polymerase

Additional binding sites for anionic phospholipids and calcium ions in the crystal structures of complexes of the C2 domain of protein kinase calpha.

Antigenically profound amino acid substitutions occur during large population passages of foot-and-mouth disease virus

Autoproteolytic Activity Derived from the Infectious Bursal Disease Virus Capsid Protein

Biochemical and structural studies with neutralizing antibodies raised against foot-and-mouth disease virus.

Both cis and trans Activities of Foot-and-Mouth Disease Virus 3D Polymerase Are Essential for Viral RNA Replication ⬇️

Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine

Cloning, purification and preliminary crystallographic studies of the 2AB protein from hepatitis A virus

Conformational changes in motif D of RdRPs as fidelity determinant.

Cryo-EM near-atomic structure of a dsRNA fungal virus shows ancient structural motifs preserved in the dsRNA viral lineage

Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site

Crystal structure of catalase HPII from Escherichia coli

Crystallization and preliminary X-ray analysis of clade I catalases from Pseudomonas syringae and Listeria seeligeri.

Crystallization and preliminary X-ray analysis of human rhinovirus serotype 2 (HRV2)

Crystallization and preliminary X-ray analysis of swine vesicular disease virus (SVDV).

Crystallization and preliminary X-ray analysis of the glycogen synthase from Pyrococcus abyssi

Crystallization and preliminary X-ray diffraction studies of the Lb proteinase from foot-and-mouth disease virus.

Cyclic peptides as conformationally restricted models of viral antigens: application to foot-and-mouth disease virus.

Decrease in pH destabilizes individual vault nanocages by weakening the inter-protein lateral interaction.

Efficient neutralization of foot-and-mouth disease virus by monovalent antibody binding

Epitope insertion at the N-terminal molecular switch of the rabbit hemorrhagic disease virus T = 3 capsid protein leads to larger T = 4 capsids

Evolution of cell recognition by viruses: a source of biological novelty with medical implications

Evolution subverting essentiality: dispensability of the cell attachment Arg-Gly-Asp motif in multiply passaged foot-and-mouth disease virus.

Flexibility of the major antigenic loop of foot-and-mouth disease virus bound to a Fab fragment of a neutralising antibody: structure and neutralisation

Induced pocket to accommodate the cell attachment Arg-Gly-Asp motif in a neutralizing antibody against foot-and-mouth-disease virus

Infectious Bursal Disease Virus VP3 Upregulates VP1-Mediated RNA-Dependent RNA Replication

Infectious bursal disease virus capsid assembly and maturation by structural rearrangements of a transient molecular switch

Insights into minor group rhinovirus uncoating: the X-ray structure of the HRV2 empty capsid

Mechanical stability and reversible fracture of vault particles

Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition

Molecular and Functional Bases of Selection against a Mutation Bias in an RNA Virus.

Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition

Multiple virulence determinants of foot-and-mouth disease virus in cell culture

Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding

New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach

Preliminary analysis of two and three dimensional crystals of vault ribonucleoprotein particles

Probing degeneracy in antigen-antibody recognition at the immunodominant site of foot-and-mouth disease virus.

Purification, crystallization and preliminary X-ray diffraction analysis of the RNA-dependent RNA polymerase from Thosea asigna virus

RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

Rapid selection in modified BHK-21 cells of a foot-and-mouth disease virus variant showing alterations in cell tropism

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activity

SARS-CoV-2 Mutant Spectra at Different Depth Levels Reveal an Overwhelming Abundance of Low Frequency Mutations

SARS-CoV-2 Point Mutation and Deletion Spectra and Their Association with Different Disease Outcomes

Sequential structures provide insights into the fidelity of RNA replication

Structural and mechanistic insights into the association of PKC -C2 domain to PtdIns(4,5)P2

Structural basis for host membrane remodeling induced by protein 2B of hepatitis A virus

Structural characterization of the Rabphilin-3A-SNAP25 interaction

Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

Structural insights into the multifunctional protein VP3 of birnaviruses

Structural variability of A-DNA in crystals of the octamer d(pCpCpCpGpCpGpGpG)

Structure and dsRNA-binding activity of the Birnavirus Drosophila X Virus VP3 protein

Structure and function of the NS5 methyltransferase domain from Usutu virus

Structure and supramolecular packing features of the dipeptide Arg-Val acetate

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

Structure of Swine Vesicular Disease Virus: Mapping of Changes Occurring during Adaptation of Human Coxsackie B5 Virus To Infect Swine

Structure of eIF4E in Complex with an eIF4G Peptide Supports a Universal Bipartite Binding Mode for Protein Translation

Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA.

Structure of human rhinovirus serotype 2 (HRV2)

Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains

Structure of the complex of an Fab fragment of a neutralizing antibody with foot-and-mouth disease virus: positioning of a highly mobile antigenic loop

Structure of the major antigenic loop of foot-and-mouth disease virus complexed with a neutralizing antibody: direct involvement of the Arg-Gly-Asp motif in the interaction

Supramolecular arrangement of the full-length Zika virus NS5

The 2.6-Angstrom structure of infectious bursal disease virus-derived T=1 particles reveals new stabilizing elements of the virus capsid

The Crystal Structure of a Cardiovirus RNA-Dependent RNA Polymerase Reveals an Unusual Conformation of the Polymerase Active Site

The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases

The T=1 capsid protein of Penicillium chrysogenum virus is formed by a repeated helix-rich core indicative of gene duplication.

The coat protein of Rabbit hemorrhagic disease virus contains a molecular switch at the N-terminal region facing the inner surface of the capsid.

The mechanism of vault opening from the high resolution structure of the N-terminal repeats of MVP

The need for a shared database infrastructure: combining X-ray crystallography and electron microscopy

The structure of a protein primer-polymerase complex in the initiation of genome replication

Uncoating of common cold virus is preceded by RNA switching as determined by X-ray and cryo-EM analyses of the subviral A-particle