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List of works by Claus-Michael Lehr

16HBE14o- human bronchial epithelial cell layers express P-glycoprotein, lung resistance-related protein, and caveolin-1.

scientific article published in April 2003

A 3D co-culture of three human cell lines to model the inflamed intestinal mucosa for safety testing of nanomaterials

scientific article published on 4 March 2015

A Design of Experiment Study of Nanoprecipitation and Nano Spray Drying as Processes to Prepare PLGA Nano- and Microparticles with Defined Sizes and Size Distributions

scientific article published on 13 February 2015

A Model for the Transient Subdiffusive Behavior of Particles in Mucus

scientific article published on January 2017

A comparative evaluation of corneal epithelial cell cultures for assessing ocular permeability.

scientific article

A dynamic ratio of the alpha+ and alpha- isoforms of the tight junction protein ZO-1 is characteristic of Caco-2 cells and correlates with their degree of differentiation

scientific article published on 7 May 2010

A hydrophobic starch polymer for nanoparticle-mediated delivery of docetaxel

scientific article published on 29 November 2011

A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes

scientific article published in January 2018

A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations

scientific article published on 14 October 2010

A nonviral DNA delivery system based on surface modified silica-nanoparticles can efficiently transfect cells in vitro.

scientific article published on November 2000

A novel cell compatible impingement system to study in vitro drug absorption from dry powder aerosol formulations

scientific article published on 17 August 2008

A strategy for in-silico prediction of skin absorption in man.

scientific article published on 29 May 2015

A three-dimensional coculture of enterocytes, monocytes and dendritic cells to model inflamed intestinal mucosa in vitro

scientific article published on November 2010

An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier

scientific article

Anti-infectives in Drug Delivery-Overcoming the Gram-Negative Bacterial Cell Envelope

scientific article published on 5 March 2016

Antibiotic-free nanotherapeutics: ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors

scientific article

Antigen delivery via hydrophilic PEG-b-PAGE-b-PLGA nanoparticles boosts vaccination induced T cell immunity

scientific article

Aspherical and Spherical InvA497-Functionalized Nanocarriers for Intracellular Delivery of Anti-Infective Agents

scholarly article by Arianna Castoldi et al published 5 December 2018 in Pharmaceutical Research

Assessing transferrin modification of liposomes by atomic force microscopy and transmission electron microscopy

scientific article published on 01 July 2005

Assessment of mucoadhesion by a resonant mirror biosensor.

scientific article published on 23 June 2006

Assessment of transport rates of proteins and peptides across primary human alveolar epithelial cell monolayers

scientific article published on 14 March 2006

Atomic force microscopy and analytical ultracentrifugation for probing nanomaterial protein interactions

scientific article published on 25 May 2012

Author Correction: Extracellular vesicles protect glucuronidase model enzymes during freeze-drying

scientific article published on 25 October 2019

Autologous co-culture of primary human alveolar macrophages and epithelial cells for investigating aerosol medicines. Part I: model characterisation.

scientific article published in September 2016

Autologous co-culture of primary human alveolar macrophages and epithelial cells for investigating aerosol medicines. Part II: evaluation of IL-10-loaded microparticles for the treatment of lung inflammation.

scientific article published in September 2016

Automated measurement of permeation and dissolution of propranolol HCl tablets using sequential injection analysis

scientific article published on 05 August 2006

Bacteriomimetic invasin-functionalized nanocarriers for intracellular delivery

scientific article published on 29 October 2015

Binding and transport of some bioadhesive plant lectins across Caco-2 cell monolayers

scientific article published on December 1993

Binding, uptake, and transport of hypericin by Caco-2 cell monolayers

scientific article published on 01 October 1997

Biodegradable microparticles as a two-drug controlled release formulation: a potential treatment of inflammatory bowel disease

scientific article

Biodegradable monodispersed nanoparticles prepared by pressure homogenization-emulsification

scientific article

Biodegradable starch derivatives with tunable charge density-synthesis, characterization, and transfection efficiency

scientific article

Biological barriers and nanomedicine--timely challenges in advanced drug delivery research

scientific article published on 11 April 2009

Biological barriers--a need for novel tools in nanotoxicology and nanomedicine. Preface

scientific article published on 01 April 2011

Biopharmaceutical characterization of the telomerase inhibitor BRACO19.

scientific article published on 4 May 2006

Biopharmaceutical in vitro characterization of CPZEN-45, a drug candidate for inhalation therapy of tuberculosis

scientific article published on 01 August 2013

Budesonide Loaded PLGA Nanoparticles for Targeting the Inflamed Intestinal Mucosa--Pharmaceutical Characterization and Fluorescence Imaging

scientific article published on 30 December 2015

Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections.

scientific article

Can lifecycle management safeguard innovation in the pharmaceutical industry?

article

Carrier interactions with the biological barriers of the lung: advanced in vitro models and challenges for pulmonary drug delivery

scientific article published on 29 May 2014

Cationic poly(lactide-co-glycolide) nanoparticles as efficient in vivo gene transfection agents.

scientific article

Cationic silica nanoparticles as gene carriers: synthesis, characterization and transfection efficiency in vitro and in vivo.

scientific article published on September 2004

Cationic solid-lipid nanoparticles can efficiently bind and transfect plasmid DNA.

scientific article published on December 2001

Cell and tissue-based in vitro models for improving the development of oral inhalation drug products

scientific article

Cell culture models and nanobiotechnology--contemporary topics in advanced drug delivery research

scientific article published on 01 July 2005

Cell culture models of the respiratory tract relevant to pulmonary drug delivery.

scientific article

Cellular delivery of polynucleotides by cationic cyclodextrin polyrotaxanes.

scientific article

Cellular responses after exposure of lung cell cultures to secondary organic aerosol particles

scientific article

Characterization and evaluation of a modified PVPA barrier in comparison to Caco-2 cell monolayers for combined dissolution and permeation testing

scientific article

Characterization and evaluation of β-glucan formulations as injectable implants for protein and peptide delivery.

scientific article

Characterization of microcapsules by confocal laser scanning microscopy: structure, capsule wall composition and encapsulation rate.

scientific article

Charge-dependent interaction of self-emulsifying oil formulations with Caco-2 cells monolayers: binding, effects on barrier function and cytotoxicity

scientific article published on 01 December 2000

Chemical coupling of a monoclonal antisurfactant protein-B antibody to human urokinase for targeting surfactant-incorporating alveolar fibrin

scientific article

Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides.

scientific article published on 9 August 2007

Co-culture of human alveolar epithelial (hAELVi) and macrophage (THP-1) cell lines

scientific article published on 23 November 2017

Computational modeling of the sugar-lectin interaction

scientific article published on March 2004

Conformational change of membrane proteins leads to shape changes of red blood cells

scientific article published on 5 April 2006

Correlation between stratum corneum/water-partition coefficient and amounts of flufenamic acid penetrated into the stratum corneum

scientific article

Coupling of biotin-(poly(ethylene glycol))amine to poly(D,L-lactide-co-glycolide) nanoparticles for versatile surface modification

scientific article published on 23 June 2007

Crossing biological barriers for advanced drug delivery

scientific article published on 24 March 2013

Decomposition of the telomere-targeting agent BRACO19 in physiological media results in products with decreased inhibitory potential

scientific article published on 20 January 2008

Delivery of ethinylestradiol from film forming polymeric solutions across human epidermis in vitro and in vivo in pigs

scientific article published on 22 December 2006

Depletion of alveolar macrophages by clodronate-liposomes aggravates ischemia-reperfusion injury of the lung

scientific article published in January 2005

Design of polyamines-grafted starches for nucleotide analogues delivery: in vitro evaluation of the anticancer activity

scientific article published on 15 September 2016

Design of rolipram-loaded nanoparticles: comparison of two preparation methods

scientific article published in April 2001

Design of starch-graft-PEI polymers: an effective and biodegradable gene delivery platform

scientific article published on 11 April 2014

Development and characterization of film forming polymeric solutions for skin drug delivery

scientific article published on 27 July 2006

Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3).

scientific article published on 29 August 2005

Development of a new aerosol delivery system for systemic pulmonary delivery in anaesthetized and orotracheal intubated rats

scientific article published in July 2001

Development of artemether-loaded nanostructured lipid carrier (NLC) formulation for topical application

scientific article published on 5 October 2014

Developments in the area of bioadhesive drug delivery systems

scientific article

Dexamethasone-loaded nanoparticle-coated microparticles: Correlation between in vitro drug release and drug transport across Caco-2 cell monolayers

scientific article published in August 2007

Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus

scientific article published on 13 June 2016

Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages.

scientific article

Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C.

scientific article published on 12 November 2002

Differentiation potential of human pancreatic stem cells for epithelial- and endothelial-like cell types

scientific article published on 9 July 2008

Dissolution techniques for in vitro testing of dry powders for inhalation

scientific article published on 20 April 2012

Dissolution testing of powders for inhalation: influence of particle deposition and modeling of dissolution profiles

scientific article published on 23 May 2014

Drug distribution in human skin using two different in vitro test systems: comparison with in vivo data

scientific article

Drug transport across pulmonary epithelial cell monolayers: effects of particle size, apical liquid volume, and deposition technique

scientific article

Dual flow bioreactor with ultrathin microporous TEER sensing membrane for evaluation of nanoparticle toxicity

article

Effect of PEGylation on the stability of liposomes during nebulisation and in lung surfactant

scientific article published in September 2006

Effect of cationic lipid and matrix lipid composition on solid lipid nanoparticle-mediated gene transfer

scientific article published in March 2004

Efficient telomerase inhibition in human non-small cell lung cancer cells by liposomal delivery of 2'-O-methyl-RNA.

scientific article

Embryonic chicken trachea as a new in vitro model for the investigation of mucociliary particle clearance in the airways

scientific article

Enhanced cellular delivery of idarubicin by surface modification of propyl starch nanoparticles employing pteroic acid conjugated polyvinyl alcohol.

scientific article

Erratum to: Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD

article

Estimation of paracellular conductance of primary rat alveolar epithelial cell monolayers

scientific article

Expression and Activity of Breast Cancer Resistance Protein (BCRP/ABCG2) in Human Distal Lung Epithelial Cells In Vitro

scientific article

Expression and function of the epithelial sodium channel δ-subunit in human respiratory epithelial cells in vitro

scientific article published on 13 February 2015

Expression of ABC-transporters in human corneal tissue and the transformed cell line, HCE-T.

scientific article published on April 2007

Extracellular vesicles protect glucuronidase model enzymes during freeze-drying

scientific article published in Scientific Reports

Finite dose skin mass balance including the lateral part: comparison between experiment, pharmacokinetic modeling and diffusion models

scientific article published on 22 October 2012

Focused Ultrasound as a Scalable and Contact-Free Method to Manufacture Protein-Loaded PLGA Nanoparticles

scientific article published on 31 March 2015

From the structure of the skin barrier and dermal formulations to in vitro transport models for skin absorption: skin research in the Netherlands and in Germany

scientific article published on 29 July 2013

Human alveolar epithelial cells expressing tight junctions to model the air-blood barrier

scientific article published on 17 March 2016

Human skin penetration of flufenamic acid: in vivo/in vitro correlation (deeper skin layers) for skin samples from the same subject

scientific article published in March 2002

Human vascular endothelial cells in primary cell culture for the evaluation of nanoparticle bioadhesion

scientific article published in September 2006

Hyaluronic acid-modified DOTAP/DOPE liposomes for the targeted delivery of anti-telomerase siRNA to CD44-expressing lung cancer cells

scientific article

IL-17A-mediated expression of epithelial IL-17C promotes inflammation during acute Pseudomonas aeruginosa pneumonia

scientific article

Impact of PEG and PEG-b-PAGE modified PLGA on nanoparticle formation, protein loading and release

scientific article

Improved input parameters for diffusion models of skin absorption

scientific article published on 22 May 2012

Improved photostability and reduced skin permeation of tretinoin: Development of a semisolid nanomedicine

scientific article published in September 2011

In vitro and in vivo performance of biocompatible negatively-charged salbutamol-loaded nanoparticles

scientific article

In vitro assessment of transferrin-conjugated liposomes as drug delivery systems for inhalation therapy of lung cancer

scientific article published on 22 July 2006

In vitro cell response to a polymer surface micropatterned by laser interference lithography

scientific article published in May 2005

In vitro models for evaluating safety and efficacy of novel technologies for skin drug delivery

scientific article published on 6 September 2016

In vitro systems for studying epithelial transport of macromolecules

scientific article

In vitro toxicological screening of nanoparticles on primary human endothelial cells and the role of flow in modulating cell response

scientific article published on 3 September 2013

In-silico model of skin penetration based on experimentally determined input parameters. Part I: experimental determination of partition and diffusion coefficients.

scientific article published on 29 May 2007

In-silico model of skin penetration based on experimentally determined input parameters. Part II: mathematical modelling of in-vitro diffusion experiments. Identification of critical input parameters

scientific article published on 15 June 2007

Influence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicity

scientific article published on 17 March 2016

Influence of apical fluid volume on the development of functional intercellular junctions in the human epithelial cell line 16HBE14o-: implications for the use of this cell line as an in vitro model for bronchial drug absorption studies

scientific article published on 27 April 2002

Influence of human skin specimens consisting of different skin layers on the result of in vitro permeation experiments

scientific article published on 11 January 2008

Influence of nanoencapsulation on human skin transport of flufenamic acid

scientific article published on 04 May 2006

Influence of particle size and material properties on mucociliary clearance from the airways

scientific article published on August 2010

Influence of the application area on finite dose permeation in relation to drug type applied

scientific article published on 01 March 2012

Influence of vitamin E TPGS poly(ethylene glycol) chain length on apical efflux transporters in Caco-2 cell monolayers

scientific article published on 10 January 2006

Influences of process parameters on nanoparticle preparation performed by a double emulsion pressure homogenization technique

scientific article published in March 2000

Influences of process parameters on preparation of microparticle used as a carrier system for omega - 3 unsaturated fatty acid ethyl esters used in supplementary nutrition

scientific article

Infrared densitometry: a fast and non-destructive method for exact stratum corneum depth calculation for in vitro tape-stripping

scientific article published on 19 February 2010

Inhalable Clarithromycin Microparticles for Treatment of Respiratory Infections

scientific article

Inhalative nanomedicine--opportunities and challenges.

scientific article published on July 2009

Interaction of metal oxide nanoparticles with lung surfactant protein A

scientific article published on 05 November 2010

Interrelation of permeation and penetration parameters obtained from in vitro experiments with human skin and skin equivalents

scientific article published in August 2001

Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination

scientific article published on 18 March 2015

Isolation, cultivation, and application of human alveolar epithelial cells

scientific article published on 01 January 2012

Itaconic Acid Increases the Efficacy of Tobramycin against Pseudomonas aeruginosa Biofilms

scientific article published on 22 July 2020

Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles

scholarly article by Hanzey Yasar et al published 19 September 2018 in Journal of Nanobiotechnology

Large porous particle impingement on lung epithelial cell monolayers--toward improved particle characterization in the lung

scientific article published on May 2003

Laser ablation patterning by interference induces directional cell growth.

scientific article

Laser interference lithography as a new and efficient technique for micropatterning of biopolymer surface

scientific article published in May 2005

Lectin-functionalized liposomes for pulmonary drug delivery: effect of nebulization on stability and bioadhesion

scientific article

Lectin-mediated drug delivery: discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model

scientific article

Lectin-mediated drug delivery: the second generation of bioadhesives

scientific article

Lectin-mediated drug targeting: history and applications

scientific article published on March 2004

Lectin-sugar interaction. Calculated versus experimental binding energies

scientific article published in March 2002

Lectins and glycoconjugates in drug delivery and targeting

scientific article published in March 2004

Macrophage uptake of cylindrical microparticles investigated with correlative microscopy

scientific article

Mastering the Gram-negative bacterial barrier – Chemical approaches to increase bacterial bioavailability of antibiotics

scientific article published on 09 March 2021

Mechanism of inhibition of P-glycoprotein mediated efflux by vitamin E TPGS: influence on ATPase activity and membrane fluidity

scientific article published on 17 March 2007

Modeling the human skin barrier--towards a better understanding of dermal absorption

scientific article published on 22 December 2012

Modelling the bronchial barrier in pulmonary drug delivery: A human bronchial epithelial cell line supplemented with human tracheal mucus

scientific article

Modified hCFTR mRNA restores normal lung function in a mouse model of cystic fibrosis

scholarly article published 13 October 2017

Mono- and Cocultures of Bronchial and Alveolar Epithelial Cells Respond Differently to Proinflammatory Stimuli and Their Modulation by Salbutamol and Budesonide

scientific article

Monolayers of human alveolar epithelial cells in primary culture for pulmonary absorption and transport studies

scientific article published on 01 May 1999

Monolayers of porcine alveolar epithelial cells in primary culture as an in vitro model for drug absorption studies

scientific article

Mucociliary clearance of micro- and nanoparticles is independent of size, shape and charge--an ex vivo and in silico approach.

scientific article published on 29 December 2011

Mucus as a barrier to lipophilic drugs.

scientific article published on 29 May 2013

Multilayer coating of gold nanoparticles with drug-polymer coadsorbates.

scientific article published on 21 October 2010

Multiphoton microscopy for the investigation of dermal penetration of nanoparticle-borne drugs

scientific article published on 18 May 2006

Murine alveolar epithelial cells and their lentivirus-mediated immortalisation

scientific article published on 01 May 2018

Nano- and microparticulate drug carriers for targeting of the inflamed intestinal mucosa

scientific article published on 25 January 2012

Nano- and microscaled particles for drug targeting to inflamed intestinal mucosa: a first in vivo study in human patients

scientific article

Nanoencapsulation in Lipid-Core Nanocapsules Controls Mometasone Furoate Skin Permeability Rate and Its Penetration to the Deeper Skin Layers

scientific article published in 2014

Nanoparticle Targeting to Scalp Hair Follicles: New Perspectives for a Topical Therapy for Alopecia Areata

scientific article published on 02 July 2019

Nanoparticle geometry and surface orientation influence mode of cellular uptake.

scientific article published on 22 February 2013

Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells

scientific article published on 19 August 2009

Nanoparticles for transcutaneous vaccination

scientific article published on 19 August 2011

Nanoparticles made from novel starch derivatives for transdermal drug delivery.

scientific article published on 21 August 2009

Nanoparticles made of fluorescence-labelled Poly(L-lactide-co-glycolide): preparation, stability, and biocompatibility

scientific article published on September 2006

Nanoparticles--an efficient carrier for drug delivery into the hair follicles

scientific article published in November 2006

Nano‐in‐Microparticles for Aerosol Delivery of Antibiotic‐Loaded, Fucose‐Derivatized, and Macrophage‐Targeted Liposomes to Combat Mycobacterial Infections: In Vitro Deposition, Pulmonary Barrier Interactions, and Targeted Delivery

scientific article published in 2022

New Horizons in the Development of Novel Needle-Free Immunization Strategies to Increase Vaccination Efficacy

scientific article

Non-invasive delivery of nanoparticles to hair follicles: a perspective for transcutaneous immunization

scientific article published on 2 January 2013

Nortriptyline for smoking cessation: release and human skin diffusion from patches.

scientific article

Nortriptyline hydrochloride skin absorption: development of a transdermal patch.

scientific article

Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine

scientific article published on 08 October 2015

Not ready to use – overcoming pitfalls when dispersing nanoparticles in physiological media

article

OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro

scientific article published on 07 August 2019

Online monitoring of transepithelial electrical resistance (TEER) in an apparatus for combined dissolution and permeation testing

scientific article published on 25 March 2010

Optical tweezers reveal relationship between microstructure and nanoparticle penetration of pulmonary mucus

scientific article

Optimization of the TRAP assay to evaluate specificity of telomerase inhibitors

scientific article published on December 2005

Oral endotracheal intubation of rats for intratracheal instillation and aerosol drug delivery.

scientific article published in July 2001

Organic cation transport in rabbit alveolar epithelial cell monolayers

scientific article published on August 1999

Organic cation transporter function in different in vitro models of human lung epithelium

scientific article published on 18 August 2015

P-glycoprotein (MDR1) functional activity in human alveolar epithelial cell monolayers.

scientific article

PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease

scientific article published on 29 September 2013

PLGA nanoparticles stabilized with cationic surfactant: safety studies and application in oral delivery of paclitaxel to treat chemical-induced breast cancer in rat.

scientific article published on 9 September 2009

Particle based vaccine formulations for transcutaneous immunization

scientific article published on 18 June 2013

Penetration of topically applied nanocarriers into the hair follicles of dog and rat dorsal skin and porcine ear skin

scientific article

Permeability assessment for solid oral drug formulations based on Caco-2 monolayer in combination with a flow through dissolution cell

scientific article published on 28 October 2006

Permeability of the reconstructed human epidermis model Episkin in comparison to various human skin preparations

scientific article published in September 2006

Permutation Test (PT) and Tolerated Difference Test (TDT): two new, robust and powerful nonparametric tests for statistical comparison of dissolution profiles

scientific article published on 27 November 2012

Polysaccharide sub-MicroCarrier for Improved Pulmonary Delivery of Poorly Soluble Anti-infective Ciprofloxacin: Preparation, Characterization and Influence of Size on Cellular Uptake

scientific article published on 9 February 2018

Porcine alveolar epithelial cells in primary culture: morphological, bioelectrical and immunocytochemical characterization

scientific article published on 9 August 2006

Preclinical safety and efficacy models for pulmonary drug delivery of antimicrobials with focus on in vitro models

scientific article

Preparation and characterization of cationic PLGA nanospheres as DNA carriers.

scientific article

Preparation and characterization of chitosan and trimethyl-chitosan-modified poly-(epsilon-caprolactone) nanoparticles as DNA carriers.

scientific article published on 10 August 2005

Preparation, characterisation and in vitro antibacterial property of ciprofloxacin-loaded nanostructured lipid carrier for treatment of Bacillus subtilis infection

scientific article published on 01 January 2019

Process optimization and biocompatibility of cell carriers suitable for automated magnetic manipulation.

scientific article published on 8 September 2011

Propidium iodide labeling of nanoparticles as a novel tool for the quantification of cellular binding and uptake

scientific article published on 05 January 2011

Pulmonary cell culture models to study the safety and efficacy of innovative aerosol medicines

scientific article published on 01 June 2008

Pulmonary delivery and tissue distribution of aerosolized antisense 2′-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung ⬇️

scientific article published on May 4, 2012

Pulmonary drug delivery: from generating aerosols to overcoming biological barriers-therapeutic possibilities and technological challenges

scientific article published on 04 June 2013

Pulmonary drug delivery: medicines for inhalation.

scientific article published on January 2010

Pulmonary surfactant is indispensable in order to simulate the in vivo situation

scientific article

Recommendations for the Choice of Inhalatory Systems for Drug Prescription

scientific article published on 01 December 2001

Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile.

scientific article

Reoxygenation results in cell death of human alveolar epithelial cells

scientific article published in October 2004

Salbutamol is actively absorbed across human bronchial epithelial cell layers.

scientific article published on 27 January 2005

Scope and relevance of a pulmonary biopharmaceutical classification system AAPS/FDA/USP Workshop March 16-17th, 2015 in Baltimore, MD

article

Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane

scientific article published on 05 February 2021

Selective follicular targeting by modification of the particle sizes

scientific article published on 16 November 2010

Semi-automated nanoprecipitation-system--an option for operator independent, scalable and size adjustable nanoparticle synthesis

scientific article published on 30 December 2014

Silica nanoparticles modified with aminosilanes as carriers for plasmid DNA

scientific article published on 01 March 2000

Simultaneous in vivo visualization and localization of solid oral dosage forms in the rat gastrointestinal tract by magnetic resonance imaging (MRI)

scientific article published on 01 August 1997

Size-Limited Penetration of Nanoparticles into Porcine Respiratory Mucus after Aerosol Deposition

scientific article published on 9 March 2016

Size-dependent bioadhesion of micro- and nanoparticulate carriers to the inflamed colonic mucosa.

scientific article

Solid Phase Extraction as an Innovative Separation Method for Measuring Free and Entrapped Drug in Lipid Nanoparticles

scientific article published on 23 July 2015

Soluplus® as an effective absorption enhancer of poorly soluble drugs in vitro and in vivo

scientific article published on 08 December 2011

Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/neu by human dendritic cells

scientific article published on 26 May 2015

Squalenoylation of Chitosan: A Platform for Drug Delivery?

scientific article published on 29 July 2015

Stabilisation by freeze-drying of cationically modified silica nanoparticles for gene delivery.

scientific article published in November 2003

Starch-Chitosan Polyplexes: A Versatile Carrier System for Anti-Infectives and Gene Delivery

scientific article published on 01 March 2018

Study of beta-lactoglobulin/acacia gum complex coacervation by diffusing-wave spectroscopy and confocal scanning laser microscopy

scientific article

Sustained-release liquisolid compact tablets containing artemether-lumefantrine as alternate-day regimen for malaria treatment to improve patient compliance

scientific article

Systemic delivery of cetrorelix to rats by a new aerosol delivery system

scientific article published in June 2001

Systemic delivery of the GnRH antagonist cetrorelix by intratracheal instillation in anesthetized rats

scientific article published on 01 January 2000

TEWL measurements as a routine method for evaluating the integrity of epidermis sheets in static Franz type diffusion cells in vitro. Limitations shown by transport data testing

scientific article

Targeted delivery of Cyclosporine A by polymeric nanocarriers improves the therapy of inflammatory bowel disease in a relevant mouse model

scientific article published on 11 July 2017

Template-Assisted Polyelectrolyte Encapsulation of Nanoparticles into Dispersible, Hierarchically Nanostructured Microfibers

scientific article published on 15 February 2011

The Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) In Vitro System: Design and Experimental Protocol ⬇️

scientific article published on August 1, 2010

The buccal mucosa as a route for TiO2 nanoparticle uptake

scientific article published on 29 May 2014

The cell line NCl-H441 is a useful in vitro model for transport studies of human distal lung epithelial barrier

scientific article published on 20 February 2014

The effect of polymer size and charge of molecules on permeation through synovial membrane and accumulation in hyaline articular cartilage.

scientific article

The human epidermis models EpiSkin, SkinEthic and EpiDerm: an evaluation of morphology and their suitability for testing phototoxicity, irritancy, corrosivity, and substance transport.

scientific article

The influence of physicochemical parameters on the efficacy of non-viral DNA transfection complexes: a comparative study

scientific article published on September 2006

The interplay of lung surfactant proteins and lipids assimilates the macrophage clearance of nanoparticles

scientific article

The physicochemical parameters of marker compounds and vehicles for use in in vitro percutaneous absorption studies.

scientific article published in May 2008

The role of corneocytes in skin transport revised--a combined computational and experimental approach

scientific article published on 25 February 2009

The role of mucus on drug transport and its potential to affect therapeutic outcomes

scientific article

The use of reconstructed human epidermis for skin absorption testing: Results of the validation study

scientific article

Tight junctions form a barrier in porcine hair follicles

scientific article

Tissue distribution of moxaverine-hydrochloride in the rabbit eye and plasma

scientific article published in June 2005

Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA.

scientific article

Towards an in vitro model of cystic fibrosis small airway epithelium: characterisation of the human bronchial epithelial cell line CFBE41o-.

scientific article published on 25 October 2005

Tracing molecular and structural changes upon mucolysis with N-acetyl cysteine in human airway mucus

scientific article

Transfection with different colloidal systems: comparison of solid lipid nanoparticles and liposomes

scientific article published in June 2004

Transfollicular delivery takes root: the future for vaccine design?

scientific article published in January 2014

Transport of proteolytic enzymes across Caco-2 cell monolayers

scientific article

Treatment of lung cancer via telomerase inhibition: self-assembled nanoplexes versus polymeric nanoparticles as vectors for 2'-O-Methyl-RNA.

scientific article

Uptake of nanoparticles by alveolar macrophages is triggered by surfactant protein A.

scientific article

Visualization and quantification of polymer distribution in microcapsules by confocal laser scanning microscopy (CLSM).

scientific article

Vitamin E TPGS P-glycoprotein inhibition mechanism: influence on conformational flexibility, intracellular ATP levels, and role of time and site of access

scientific article published in June 2010

Wistar rat skin as surrogate for human skin in nortriptyline hydrochloride patch studies

scientific article published on 23 September 2009

[Pharmacy at the University of the Saarlands]

scientific article published on 01 July 1997

miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity

scientific article

pH profiles in human skin: influence of two in vitro test systems for drug delivery testing

scientific article

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